{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:57:02Z","timestamp":1791928622915,"version":"4.3.4"},"reference-count":64,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2022,10,21]],"date-time":"2022-10-21T00:00:00Z","timestamp":1666310400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Zagazig, Suez Canal and Port Said Universities","award":["PNURSP2022R155"],"award-info":[{"award-number":["PNURSP2022R155"]}]},{"name":"Zagazig, Suez Canal and Port Said Universities","award":["TURSP 2020\/257"],"award-info":[{"award-number":["TURSP 2020\/257"]}]},{"name":"Taif University Researchers","award":["PNURSP2022R155"],"award-info":[{"award-number":["PNURSP2022R155"]}]},{"name":"Taif University Researchers","award":["TURSP 2020\/257"],"award-info":[{"award-number":["TURSP 2020\/257"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antibiotics"],"abstract":"<jats:p>Listeriosis is one of the most common foodborne diseases caused by Listeria monocytogenes (L. monocytogenes). A poor prognosis has been recorded for the invasive listeriosis, especially neurolisteriosis. In several countries throughout the world, foodborne infections with L. monocytogenes exceeded the legal safety limits in animal sourced foods. Therefore, we decided to investigate the variability, virulence and antimicrobial resistance profiles of this pathogen. Both phenotypic and genotypic methods were used for identifying L. monocytogenes isolates and confirming their virulence profiles. The antimicrobial resistances and their correlation analysis with the existence of virulence genes were detected. Additionally, sequencing and phylogenetic analysis based on L. monocytogenes inlA and inlB genes were undertaken. The prevalence rate (11.9%) and the resistance profiles of L. monocytogenes were shocking. The multi-drug resistance (MDR) phenotypes were common among our isolates (64.9%). Fortunately, the resistance phenotypes were always associated with low virulence arrays and the MDR strains possessed low virulence fitness. Herein, the high genotypic and phenotypic diversity of L. monocytogenes isolates and their weak clonality and adaptability highlighted the difficulty in controlling and managing this pathogen. Therefore, it is important to add more restriction guidelines from national authorities on the consumption of ready to eat foods.<\/jats:p>","DOI":"10.3390\/antibiotics11101447","type":"journal-article","created":{"date-parts":[[2022,10,23]],"date-time":"2022-10-23T20:43:50Z","timestamp":1666557830000},"page":"1447","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["New Insights into Listeria monocytogenes Antimicrobial Resistance, Virulence Attributes and Their Prospective Correlation"],"prefix":"10.3390","volume":"11","author":[{"given":"Mahmoud E.","family":"Elsayed","sequence":"first","affiliation":[{"name":"Department of Bacteriology, Immunology, and Mycology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia 41522, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1560-6158","authenticated-orcid":false,"given":"Marwa I.","family":"Abd El-Hamid","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Faculty of Veterinary Medicine, Zagazig University, Zagazig 44511, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Attia","family":"El-Gedawy","sequence":"additional","affiliation":[{"name":"Department of Bacteriology, Animal Health Research Institute, Dokki, Giza 12618, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1788-0038","authenticated-orcid":false,"given":"Mahmoud M.","family":"Bendary","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, Faculty of Pharmacy, Port Said University, Port Said 42511, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8273-2747","authenticated-orcid":false,"given":"Reham M.","family":"ELTarabili","sequence":"additional","affiliation":[{"name":"Department of Bacteriology, Immunology, and Mycology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia 41522, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9798-0962","authenticated-orcid":false,"given":"Majid","family":"Alhomrani","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratories Sciences, The Faculty of Applied Medical Science, Taif University, Taif 26432, Saudi Arabia"},{"name":"Centre of Biomedical Science Research (CBSR), Deanship of Scientific Research, Taif University, Taif 26432, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3174-0434","authenticated-orcid":false,"given":"Abdulhakeem S.","family":"Alamri","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratories Sciences, The Faculty of Applied Medical Science, Taif University, Taif 26432, Saudi Arabia"},{"name":"Centre of Biomedical Science Research (CBSR), Deanship of Scientific Research, Taif University, Taif 26432, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saleh A.","family":"Alghamdi","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratories Sciences, The Faculty of Applied Medical Science, Taif University, Taif 26432, Saudi Arabia"},{"name":"Centre of Biomedical Science Research (CBSR), Deanship of Scientific Research, Taif University, Taif 26432, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marwa","family":"Arnout","sequence":"additional","affiliation":[{"name":"Veterinary Quarantine, Cairo Airport, Zagazig 44511, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dalal N.","family":"Binjawhar","sequence":"additional","affiliation":[{"name":"Department of Chemistry, College of Science, Princess Nourah Bint Abdulrahman University, Riyadh 11671, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9820-4022","authenticated-orcid":false,"given":"Mohammad M.","family":"Al-Sanea","sequence":"additional","affiliation":[{"name":"Pharmaceutical Chemistry Department, College of Pharmacy, Jouf University, Sakaka 72341, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amira I.","family":"Abousaty","sequence":"additional","affiliation":[{"name":"Microbiology Department, Faculty of Science, Zagazig University, Zagazig 44511, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,10,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"529","DOI":"10.3934\/microbiol.2017.3.529","article-title":"Foodborne pathogens","volume":"3","author":"Bintsis","year":"2017","journal-title":"AIMS 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