{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T11:00:03Z","timestamp":1793444403931,"version":"4.5.0"},"reference-count":30,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2022,10,31]],"date-time":"2022-10-31T00:00:00Z","timestamp":1667174400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antibiotics"],"abstract":"<jats:p>There are growing concerns regarding the rise of antimicrobial-resistant bacteria in companion animals. This study aimed to bring new insights into the current scenario of Portugal\u2019s antimicrobial resistance bacteria isolated from companion animals with urinary tract infections and is the first to be performed during a long period on a large scale. Of a total of 17472 urine samples analyzed, 12,166 (69.6%) (CI 12,200\u201312,200) were negative for bacterial growth, and 5306 (30.4%) (95% CI 5310\u20135310) had bacterial growth. Of the culture-positive samples, 5224 (96.6%) (95% CI 5220\u20135220) were pure cultures and 82 (3.2%) (95% CI 81.9\u201382.1) had mixed growth. Escherichia coli was the most frequently isolated bacteria (n = 2360, 44.5%) (95% CI 2360\u20132360), followed by Proteus mirabilis (n = 585, 11%) (95% CI 583\u2013583), Enterococcus faecium (n = 277, 5.2%) (95% CI 277\u2013277) and Staphylococcus pseudintermedius (n = 226, 4.3%) (95% CI 226\u2013226). The overall susceptibility rates were low for erythromycin (45.3%) and clindamycin (51.3%), and high for aminoglycosides (96.3%), carbapenems (92.4%), trimethoprim-sulfamethoxazole (81.2%), and quinolones (79.9%). E. coli also showed considerable resistance to amoxicillin-clavulanic acid. The rates of multidrug-resistant bacteria are still high compared to the northern countries of Europe. This study\u2019s findings show the emergence of antibiotic resistance in the antibiotic agents commonly used in the treatment of UTIs in dogs and cats in Portugal.<\/jats:p>","DOI":"10.3390\/antibiotics11111520","type":"journal-article","created":{"date-parts":[[2022,10,31]],"date-time":"2022-10-31T23:26:32Z","timestamp":1667258792000},"page":"1520","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Bacterial Isolates from Urinary Tract Infection in Dogs and Cats in Portugal, and Their Antibiotic Susceptibility Pattern: A Retrospective Study of 5 Years (2017\u20132021)"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7940-3141","authenticated-orcid":false,"given":"Andreia","family":"Garc\u00eas","sequence":"first","affiliation":[{"name":"Inno-Servi\u00e7os Especializados em Veterin\u00e1ria, R. C\u00e2ndido de Sousa 15, 4710-300 Braga, Portugal"},{"name":"Centre for the Research and Technology of Agro-Environmental and Biological Sciences (CITAB), University of Tr\u00e1s-os-Montes and Alto Douro, Quinta de Prados, 5000-801 Vila Real, Portugal"},{"name":"Cooperativa de Ensino Superior Polit\u00e9cnico e Universit\u00e1rio (CRL-CESPU), R. Central Dada Gandra, 1317, 4585-116 Gandra, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9339-9932","authenticated-orcid":false,"given":"Ricardo","family":"Lopes","sequence":"additional","affiliation":[{"name":"Inno-Servi\u00e7os Especializados em Veterin\u00e1ria, R. C\u00e2ndido de Sousa 15, 4710-300 Braga, Portugal"},{"name":"Cooperativa de Ensino Superior Polit\u00e9cnico e Universit\u00e1rio (CRL-CESPU), R. Central Dada Gandra, 1317, 4585-116 Gandra, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-3992-3771","authenticated-orcid":false,"given":"Augusto","family":"Silva","sequence":"additional","affiliation":[{"name":"Inno-Servi\u00e7os Especializados em Veterin\u00e1ria, R. C\u00e2ndido de Sousa 15, 4710-300 Braga, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filipe","family":"Sampaio","sequence":"additional","affiliation":[{"name":"Inno-Servi\u00e7os Especializados em Veterin\u00e1ria, R. C\u00e2ndido de Sousa 15, 4710-300 Braga, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Duque","sequence":"additional","affiliation":[{"name":"Inno-Servi\u00e7os Especializados em Veterin\u00e1ria, R. 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