{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:56:07Z","timestamp":1792803367541,"version":"4.5.0"},"reference-count":84,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2023,2,13]],"date-time":"2023-02-13T00:00:00Z","timestamp":1676246400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001824","name":"Czech Science Foundation","doi-asserted-by":"publisher","award":["22-06771S"],"award-info":[{"award-number":["22-06771S"]}],"id":[{"id":"10.13039\/501100001824","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001824","name":"Czech Science Foundation","doi-asserted-by":"publisher","award":["SGS05\/LF\/2022"],"award-info":[{"award-number":["SGS05\/LF\/2022"]}],"id":[{"id":"10.13039\/501100001824","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Internal Grant Agency of the University of Ostrava","award":["22-06771S"],"award-info":[{"award-number":["22-06771S"]}],"id":[{"id":"https:\/\/ror.org\/00pyqav47","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Internal Grant Agency of the University of Ostrava","award":["SGS05\/LF\/2022"],"award-info":[{"award-number":["SGS05\/LF\/2022"]}],"id":[{"id":"https:\/\/ror.org\/00pyqav47","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antibiotics"],"abstract":"<jats:p>Aspergillus fumigatus has been designated by the World Health Organization as a critical priority fungal pathogen. Some commercially available diagnostics for many forms of aspergillosis rely on fungal metabolites. These encompass intracellular molecules, cell wall components, and extracellular secretomes. This review summarizes the shortcomings of antibody tests compared to tests of fungal products in body fluids and highlights the application of \u03b2-d-glucan, galactomannan, and pentraxin 3 in bronchoalveolar lavage fluids. We also discuss the detection of nucleic acids and next-generation sequencing, along with newer studies on Aspergillus metallophores.<\/jats:p>","DOI":"10.3390\/antibiotics12020385","type":"journal-article","created":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T02:41:56Z","timestamp":1676342516000},"page":"385","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Current and Future Pathways in Aspergillus Diagnosis"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4299-9169","authenticated-orcid":false,"given":"Radim","family":"Dobi\u00e1\u0161","sequence":"first","affiliation":[{"name":"Department of Bacteriology and Mycology, Public Health Institute in Ostrava, Partyz\u00e1nsk\u00e9 N\u00e1m\u011bst\u00ed 2633\/7, 702 00 Ostrava, Czech Republic"},{"name":"Institute of Laboratory Medicine, Faculty of Medicine, University of Ostrava, Syllabova 19, 703 00 Ostrava, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Stevens","sequence":"additional","affiliation":[{"name":"California Institute for Medical Research, 2260 Clove Drive, San Jose, CA 95128, USA"},{"name":"Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, CA 95128, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8614-7059","authenticated-orcid":false,"given":"Vladim\u00edr","family":"Havl\u00ed\u010dek","sequence":"additional","affiliation":[{"name":"Institute of Microbiology of the Czech Academy of Sciences, V\u00edde\u0148sk\u00e1 1083, 142 20 Prague, Czech Republic"},{"name":"Department of Analytical Chemistry, Faculty of Science, Palack\u00fd University, 17. Listopadu 12, 771 46 Olomouc, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,2,13]]},"reference":[{"key":"ref_1","unstructured":"World Health Organization (2022, November 11). Fungal Priority Pathogens List to Guide Research, Development and Public Health Action. Available online: https:\/\/www.who.int\/publications\/i\/item\/9789240060241."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.rmed.2018.06.029","article-title":"The spectrum of pulmonary aspergillosis","volume":"141","author":"Kanj","year":"2018","journal-title":"Respir. Med."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"S121","DOI":"10.1093\/cid\/ciaa1751","article-title":"EORTC\/MSGERC Definitions of Invasive Fungal Diseases: Summary of Activities of the Intensive Care Unit Working Group","volume":"72","author":"Bassetti","year":"2021","journal-title":"Clin. Infect. 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