{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T00:10:20Z","timestamp":1787962220069,"version":"build-2784847793"},"reference-count":32,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2023,4,25]],"date-time":"2023-04-25T00:00:00Z","timestamp":1682380800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Universidad Cient\u00edfica del Sur. Beca Cabieses","award":["2020-1"],"award-info":[{"award-number":["2020-1"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antibiotics"],"abstract":"<jats:p>Introduction: Surgical site infections (SSI) can be as high in gynecology and obstetrics surgeries compared to other areas. Antimicrobial prophylaxis is an effective tool in the prevention of SSIs; however, it is often not adequately administered, so this study aimed to understand the compliance and factors associated with the use of the clinical practice guidelines for antibiotic prophylaxis in gynecological surgeries in two hospitals in the city of Huanuco, Peru. Methods: An analytical cross-sectional study of all gynecologic surgeries performed during 2019 was performed. Compliance was determined based on the antibiotic chosen, dose, administration time, redosing, and prophylaxis duration. Age, hospital of origin, presence of comorbidities, surgery performed, as well as its duration, types of surgery, and anesthesia were considered as related factors. Results: We collected 529 medical records of patients undergoing gynecological surgery with a median age of 33 years. The prophylactic antibiotic was correctly indicated in 55.5% of cases, and the dose was correct in 31.2%. Total compliance with the five variables evaluated was only 3.9%. Cefazolin was the most commonly used antibiotic. Conclusion: Low compliance with the institutional clinical practice guidelines for antibiotic prophylaxis was identified, showing that antimicrobial prophylaxis in the hospitals studied was inadequate.<\/jats:p>","DOI":"10.3390\/antibiotics12050808","type":"journal-article","created":{"date-parts":[[2023,4,25]],"date-time":"2023-04-25T02:06:35Z","timestamp":1682388395000},"page":"808","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Compliance with Antibiotic Prophylaxis in Obstetric and Gynecological Surgeries in Two Peruvian Hospitals"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0182-703X","authenticated-orcid":false,"given":"Kovy","family":"Arteaga-Livias","sequence":"first","affiliation":[{"name":"Maestr\u00eda en Epidemiologia Clinica y Bioestadistica, Universidad Cient\u00edfica del Sur, Lima 15014, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2445-4854","authenticated-orcid":false,"given":"Vicky","family":"Panduro-Correa","sequence":"additional","affiliation":[{"name":"Facultad de Medicina, Universidad Nacional Hermilio Valdiz\u00e1n, Hu\u00e1nuco 10000, Peru"},{"name":"Escuela de Medicina, Universidad San Juan Bautista, Lima 15067, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4136-7795","authenticated-orcid":false,"given":"Jorge L.","family":"Magui\u00f1a","sequence":"additional","affiliation":[{"name":"Maestr\u00eda en Epidemiologia Clinica y Bioestadistica, Universidad Cient\u00edfica del Sur, Lima 15014, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Osada","sequence":"additional","affiliation":[{"name":"Maestr\u00eda en Epidemiologia Clinica y Bioestadistica, Universidad Cient\u00edfica del Sur, Lima 15014, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6774-9847","authenticated-orcid":false,"given":"Ali A.","family":"Rabaan","sequence":"additional","affiliation":[{"name":"Molecular Diagnostic Laboratory, Johns Hopkins Aramco Healthcare, Dhahran 31311, Saudi Arabia"},{"name":"College of Medicine, Alfaisal University, Riyadh 11533, Saudi Arabia"},{"name":"Department of Public Health and Nutrition, The University of Haripur, Haripur 22610, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiara","family":"Lijarza-Ushinahua","sequence":"additional","affiliation":[{"name":"Facultad de Medicina, Universidad Nacional Hermilio Valdiz\u00e1n, Hu\u00e1nuco 10000, Peru"},{"name":"Sociedad Cient\u00edfica de Estudiantes de Medicina (SOCIEM-HCO), Universidad Nacional Hermilio Vadliz\u00e1n, Hu\u00e1nuco 10000, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2896-1407","authenticated-orcid":false,"given":"Joshuan J.","family":"Barboza","sequence":"additional","affiliation":[{"name":"Vicerrectorado de Investigaci\u00f3n, Universidad Norbert Wiener, Lima 15046, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0706-7614","authenticated-orcid":false,"given":"Walter","family":"Gomez-Gonzales","sequence":"additional","affiliation":[{"name":"Escuela de Medicina-Filial Ica, Universidad Privada San Juan Bautista, Ica 11001, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9773-2192","authenticated-orcid":false,"given":"Alfonso J.","family":"Rodriguez-Morales","sequence":"additional","affiliation":[{"name":"Maestr\u00eda en Epidemiologia Clinica y Bioestadistica, Universidad Cient\u00edfica del Sur, Lima 15014, Peru"},{"name":"Grupo de Investigaci\u00f3n Biomedicina, Faculty of Medicine, Fundaci\u00f3n Universitaria Aut\u00f3noma de las Am\u00e9ricas, Pereira 660005, Colombia"},{"name":"GIlbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Beirut P.O. Box 36, Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,4,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1007\/s11096-018-0702-0","article-title":"Utilization of Surgical Antibiotic Prophylaxis for Obstetrics and Gynaecology Surgeries in Northern Nigeria","volume":"40","author":"Abubakar","year":"2018","journal-title":"Int. J. Clin. Pharm."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"e08529","DOI":"10.1016\/j.heliyon.2021.e08529","article-title":"The Effect of Intraoperative Glycemic Control on Surgical Site Infections among Diabetic Patients Undergoing Coronary Artery Bypass Graft (CABG) Surgery","volume":"7","author":"Hweidi","year":"2021","journal-title":"Heliyon"},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Abubakar, U., Syed Sulaiman, S.A., and Adesiyun, A.G. (2019). 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