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Until now, patients\u2019 psychosocial characteristics have not been widely explored as a potential contributor to the overuse of antibiotics. In this study, the relationship between a patient\u2019s psychosocial characteristics (self-reported in postal surveys in 2003) and the number of antibiotics they were prescribed (recorded in Finnish national registry data between 2004\u20132006) were analyzed for 19,300 working-aged Finns. Psychosocial characteristics included life satisfaction, a sense of coherence, perceived stress, hostility, and optimism. In a structural equation model, patients\u2019 adverse psychosocial characteristics were not related to increased antibiotic prescriptions in the subsequent three years. However, these characteristics were strongly associated with poor general health status, which in turn was associated with an increased number of subsequent antibiotic prescriptions. Furthermore, mediation analysis showed that individuals who used healthcare services more frequently also received more antibiotic prescriptions. The current study does not support the view that patients\u2019 adverse psychosocial characteristics are related to an increased number of antibiotic prescriptions. This could encourage physicians to actively discuss treatment options with their patients.<\/jats:p>","DOI":"10.3390\/antibiotics12061022","type":"journal-article","created":{"date-parts":[[2023,6,7]],"date-time":"2023-06-07T02:28:45Z","timestamp":1686104925000},"page":"1022","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Do Patients\u2019 Psychosocial Characteristics Impact Antibiotic Prescription Rates?"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9945-2909","authenticated-orcid":false,"given":"S\u00e4de","family":"Stenlund","sequence":"first","affiliation":[{"name":"School of Population and Public Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada"},{"name":"BC Centre for Disease Control, Vancouver, BC V5Z 4R4, Canada"},{"name":"Department of Public Health, University of Turku, 20014 Turku, Finland"},{"name":"Research Services, Turku University Hospital, 20520 Turku, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2483-8791","authenticated-orcid":false,"given":"Louise C.","family":"M\u00e2sse","sequence":"additional","affiliation":[{"name":"School of Population and Public Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada"},{"name":"BC Children\u2019s Hospital Research Institute, University of British Columbia, Vancouver, BC V5Z 4H4, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Stenlund","sequence":"additional","affiliation":[{"name":"Department of Mathematics, University of British Columbia, Vancouver, BC V6T 1Z2, Canada"},{"name":"Faculty of Science and Engineering, \u00c5bo Akademi University, 20500 Turku, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lauri","family":"Sillanm\u00e4ki","sequence":"additional","affiliation":[{"name":"Department of Public Health, University of Turku, 20014 Turku, Finland"},{"name":"Research Services, Turku University Hospital, 20520 Turku, Finland"},{"name":"Department of Public Health, University of Helsinki, 00014 Helsinki, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-7483-7778","authenticated-orcid":false,"given":"Kirstin C.","family":"Appelt","sequence":"additional","affiliation":[{"name":"Sauder School of Business, University of British Columbia, Vancouver, BC V6T 1Z2, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heli","family":"Koivumaa-Honkanen","sequence":"additional","affiliation":[{"name":"Institute of Clinical Medicine (Psychiatry), University of Eastern Finland, 70029 Kuopio, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2795-1327","authenticated-orcid":false,"given":"P\u00e4ivi","family":"Rautava","sequence":"additional","affiliation":[{"name":"Department of Public Health, University of Turku, 20014 Turku, Finland"},{"name":"Research Services, Turku University Hospital, 20520 Turku, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6648-603X","authenticated-orcid":false,"given":"Sakari","family":"Suominen","sequence":"additional","affiliation":[{"name":"Department of Public Health, University of Turku, 20014 Turku, Finland"},{"name":"Research Services, Turku University Hospital, 20520 Turku, Finland"},{"name":"School of Health Sciences, University of Sk\u00f6vde, 54128 Sk\u00f6vde, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David M.","family":"Patrick","sequence":"additional","affiliation":[{"name":"School of Population and Public Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada"},{"name":"BC Centre for Disease Control, Vancouver, BC V5Z 4R4, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,6,7]]},"reference":[{"key":"ref_1","unstructured":"(2023, March 28). 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