{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T11:06:51Z","timestamp":1785755211749,"version":"3.56.0"},"reference-count":151,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T00:00:00Z","timestamp":1713139200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Red Meat Research and Development Trust South Africa, and Department of Trade, Industry, and Competition","award":["THRIP\/22\/30\/11\/2017"],"award-info":[{"award-number":["THRIP\/22\/30\/11\/2017"]}]},{"name":"The Moses Kotane Institute (MKI) Research Fund","award":["THRIP\/22\/30\/11\/2017"],"award-info":[{"award-number":["THRIP\/22\/30\/11\/2017"]}]},{"name":"The FoodBev SETA Bursary","award":["THRIP\/22\/30\/11\/2017"],"award-info":[{"award-number":["THRIP\/22\/30\/11\/2017"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antibiotics"],"abstract":"<jats:p>Among the foodborne illnesses, listeriosis has the third highest case mortality rate (20\u201330% or higher). Emerging drug-resistant strains of Listeria monocytogenes, a causative bacterium of listeriosis, exacerbate the seriousness of this public health concern. Novel anti-Listerial compounds are therefore needed to combat this challenge. In recent years, marine actinobacteria have come to be regarded as a promising source of novel antimicrobials. Hence, our aim was to provide a narrative of the available literature and discuss trends regarding bioprospecting marine actinobacteria for new anti-Listerial compounds. Four databases were searched for the review: Academic Search Ultimate, Google Scholar, ScienceDirect, and South African Thesis and Dissertations. The search was restricted to peer-reviewed full-text manuscripts that discussed marine actinobacteria as a source of antimicrobials and were written in English from 1990 to December 2023. In total, for the past three decades (1990\u2013December 2023), only 23 compounds from marine actinobacteria have been tested for their anti-Listerial potential. Out of the 23 reported compounds, only 2-allyoxyphenol, adipostatins E\u2013G, 4-bromophenol, and ansamycins (seco-geldanamycin B, 4.5-dihydro-17-O-demethylgeldanamycin, and seco-geldanamycin) have been found to possess anti-Listerial activity. Thus, our literature survey reveals the scarcity of published assays testing the anti-Listerial capacity of bioactive compounds sourced from marine actinobacteria during this period.<\/jats:p>","DOI":"10.3390\/antibiotics13040362","type":"journal-article","created":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T11:53:53Z","timestamp":1713182033000},"page":"362","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["A Mini-Review of Anti-Listerial Compounds from Marine Actinobacteria (1990\u20132023)"],"prefix":"10.3390","volume":"13","author":[{"given":"Siyanda S.","family":"Ngema","sequence":"first","affiliation":[{"name":"Department of Biochemistry and Microbiology, University of Zululand, KwaDlangezwa 3886, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5400-343X","authenticated-orcid":false,"given":"Evelyn","family":"Madoroba","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Microbiology, University of Zululand, KwaDlangezwa 3886, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,4,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e12629","DOI":"10.1111\/jfs.12629","article-title":"Occurrence, serotypes, and characteristics of Listeria monocytogenes in meat and meat products in South Africa between 2014 and 2016","volume":"39","author":"Matle","year":"2019","journal-title":"J. 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