{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T18:38:47Z","timestamp":1793039927724,"version":"4.5.0"},"reference-count":130,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2024,6,13]],"date-time":"2024-06-13T00:00:00Z","timestamp":1718236800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antibiotics"],"abstract":"<jats:p>Antimicrobial resistance represents an alarming public health problem; its importance is related to the significant clinical implications (increased morbidity, mortality, disease duration, development of comorbidities, and epidemics), as well as its economic effects on the healthcare sector. In fact, therapeutic options are severely limited by the advent and spread of germs resistant to many antibiotics. The situation worldwide is worrying, especially in light of the prevalence of Gram-negative bacteria\u2014Klebsiella pneumoniae and Acinetobacter baumannii\u2014which are frequently isolated in hospital environments and, more specifically, in intensive care units. The problem is compounded by the ineffective treatment of infections by patients who often self-prescribe therapy. Resistant bacteria also show resistance to the latest generation antibiotics, such as carbapenems. In fact, superbacteria, grouped under the acronym extended-spectrum betalactamase (ESBL), are becoming common. Antibiotic resistance is also found in the livestock sector, with serious repercussions on animal production. In general, this phenomenon affects all members of the biosphere and can only be addressed by adopting a holistic \u201cOne Health\u201d approach. In this literature overview, a stock is taken of what has been learned about antibiotic resistance, and suggestions are proposed to stem its advance.<\/jats:p>","DOI":"10.3390\/antibiotics13060551","type":"journal-article","created":{"date-parts":[[2024,6,13]],"date-time":"2024-06-13T10:41:03Z","timestamp":1718275263000},"page":"551","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":63,"title":["Antimicrobial Resistance in Livestock: A Serious Threat to Public Health"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4173-8584","authenticated-orcid":false,"given":"Roberto","family":"Bava","sequence":"first","affiliation":[{"name":"Department of Health Sciences, University of Catanzaro Magna Gr\u00e6cia, 88100 Catanzaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9600-6401","authenticated-orcid":false,"given":"Fabio","family":"Castagna","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, University of Catanzaro Magna Gr\u00e6cia, 88100 Catanzaro, Italy"},{"name":"Mediterranean Ethnobotanical Conservatory, Sersale (CZ), 88054 Catanzaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmine","family":"Lupia","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, University of Catanzaro Magna Gr\u00e6cia, 88100 Catanzaro, Italy"},{"name":"Mediterranean Ethnobotanical Conservatory, Sersale (CZ), 88054 Catanzaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giusi","family":"Poerio","sequence":"additional","affiliation":[{"name":"ATS Val Padana, Via dei Toscani, 46100 Mantova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3031-345X","authenticated-orcid":false,"given":"Giovanna","family":"Liguori","sequence":"additional","affiliation":[{"name":"Local Health Authority, ASL, 71121 Foggia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-7759-2141","authenticated-orcid":false,"given":"Renato","family":"Lombardi","sequence":"additional","affiliation":[{"name":"IRCCS Casa Sollievo Della Sofferenza, San Giovanni Rotondo (FG), 71013 Foggia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5599-1265","authenticated-orcid":false,"given":"Maria Diana","family":"Naturale","sequence":"additional","affiliation":[{"name":"Ministry of Health, Directorate General for Health Programming, 00144 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caterina","family":"Mercuri","sequence":"additional","affiliation":[{"name":"Department of Experimental and Clinical Medicine, University \u201cMagna Graecia\u201d, 88100 Catanzaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa Maria","family":"Bulotta","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, University of Catanzaro Magna Gr\u00e6cia, 88100 Catanzaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7355-8791","authenticated-orcid":false,"given":"Domenico","family":"Britti","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, University of Catanzaro Magna Gr\u00e6cia, 88100 Catanzaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4199-207X","authenticated-orcid":false,"given":"Ernesto","family":"Palma","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, University of Catanzaro Magna Gr\u00e6cia, 88100 Catanzaro, Italy"},{"name":"Center for Pharmacological Research, Food Safety, High Tech and Health (IRC-FSH), University of Catanzaro Magna Gr\u00e6cia, 88100 Catanzaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,6,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Westblade, L.F., Errington, J., and D\u00f6rr, T. 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