{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T18:04:27Z","timestamp":1789927467106,"version":"4.0.1"},"reference-count":109,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2024,9,26]],"date-time":"2024-09-26T00:00:00Z","timestamp":1727308800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antibiotics"],"abstract":"<jats:p>Escherichia coli is a gram-negative commensal bacterium living in human and animal intestines. Its pathogenic strains lead to high morbidity and mortality, which can adversely affect people by causing urinary tract infections, food poisoning, septic shock, or meningitis. Humans can contract E. coli by eating contaminated food\u2014such as raw or undercooked raw milk, meat products, and fresh produce sold in open markets\u2014as well as by coming into contact with contaminated settings like wastewater, municipal water, soil, and faeces. Some pathogenic strains identified in Nigeria, include Enterohemorrhagic (Verotoxigenic), Enterotoxigenic, Enteropathogenic, Enteroinvasive, and Enteroaggregative E. coli. This causes acute watery or bloody diarrhoea, stomach cramps, and vomiting. Apart from the virulence profile of E. coli, antibiotic resistance mechanisms such as the presence of blaCTX-M found in humans, animals, and environmental isolates are of great importance and require surveillance and monitoring for emerging threats in resource-limited countries. This review is aimed at understanding the underlying mechanisms of evolution and antibiotic resistance in E. coli in Nigeria and highlights the use of improving One Health approaches to combat the problem of emerging infectious diseases.<\/jats:p>","DOI":"10.3390\/antibiotics13100922","type":"journal-article","created":{"date-parts":[[2024,9,26]],"date-time":"2024-09-26T11:38:34Z","timestamp":1727350714000},"page":"922","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Antimicrobial Resistance in Diverse Escherichia coli Pathotypes from Nigeria"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2566-7982","authenticated-orcid":false,"given":"Kenneth Nnamdi","family":"Anueyiagu","sequence":"first","affiliation":[{"name":"Department of Public Health Technology, Federal College of Animal Health and Production Technology, Vom 200273, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chibuzor Gerald","family":"Agu","sequence":"additional","affiliation":[{"name":"National Veterinary Research Institute, Vom 930103, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2805-6420","authenticated-orcid":false,"given":"Uzal","family":"Umar","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology and Parasitology, University of Jos, Jos 930105, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1476-2108","authenticated-orcid":false,"given":"Bruno Silvester","family":"Lopes","sequence":"additional","affiliation":[{"name":"School of Health and Life Sciences, Teesside University, Middlesbrough TS1 3BX, UK"},{"name":"National Horizons Centre, Teesside University, Darlington DL1 1HG, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,9,26]]},"reference":[{"key":"ref_1","first-page":"515","article-title":"Die Darmbakterien des Neugeborenen und Sauglinge","volume":"3","author":"Escherich","year":"1885","journal-title":"Fortschr. 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