{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T02:48:21Z","timestamp":1778122101829,"version":"3.51.4"},"reference-count":19,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2024,12,28]],"date-time":"2024-12-28T00:00:00Z","timestamp":1735344000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antibiotics"],"abstract":"<jats:p>Background Abdominal ultrasound (US) is a reliable method for visualizing gastric wall layers and measuring their thickness. The objective of this study is to characterize the ultrasound features of H. pylori-induced gastritis and assess its predictive potential role for this condition. Methods A cohort of 119 patients underwent gastroscopy with biopsy and abdominal US to evaluate antral wall thickness (AWT), submucosal wall thickness (SLT), mucosal wall thickness (MLT), gastric motility, and the presence of ingested material. They were divided into three groups: group A (normal mucosa without H. pylori infection), group B (gastritis H. pylori negative) and group C (gastritis H. pylori positive). Results: SLT and reduced gastric motility were significantly increased in the H. pylori gastritis group (p &lt; 0.001). Multivariate analysis identified SLT as the only significant independent predictor of H. pylori gastritis (p &lt; 0.001). An SLT threshold of 1.55 mm was determined as optimal for differentiating H. pylori-positive patients from -negative, yielding a sensitivity of 77% and a specificity of 72%. Conclusions These findings suggest that H. pylori gastritis is characterized by submucosal layer thickening and impaired gastric motility.<\/jats:p>","DOI":"10.3390\/antibiotics14010012","type":"journal-article","created":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T04:10:23Z","timestamp":1735618223000},"page":"12","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Ultrasound Features of Helicobacter pylori-Related Gastritis"],"prefix":"10.3390","volume":"14","author":[{"given":"Fulvia","family":"Terracciano","sequence":"first","affiliation":[{"name":"Division of Gastroenterology & Endoscopy, IRCCS, Fondazione \u201cCasa Sollievo della Sofferenza\u201d, 71013 San Giovanni Rotondo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonella","family":"Marra","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology & Endoscopy, IRCCS, Fondazione \u201cCasa Sollievo della Sofferenza\u201d, 71013 San Giovanni Rotondo, Italy"},{"name":"National Institute of Gastroenterology, IRCCS Saverio de Bellis Research Hospital, 70013 Castellana Grotte, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1003-8179","authenticated-orcid":false,"given":"Veronica","family":"Nassisi","sequence":"additional","affiliation":[{"name":"Internal Medicine Unit, Department of Clinical and Experimental Medicine, University of Messina, 98122 Messina, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiara","family":"Lillo","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology & Endoscopy, IRCCS, Fondazione \u201cCasa Sollievo della Sofferenza\u201d, 71013 San Giovanni Rotondo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4518-9949","authenticated-orcid":false,"given":"Fabrizio","family":"Bossa","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology & Endoscopy, IRCCS, Fondazione \u201cCasa Sollievo della Sofferenza\u201d, 71013 San Giovanni Rotondo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2054-8754","authenticated-orcid":false,"given":"Sonia","family":"Carparelli","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology & Endoscopy, IRCCS, Fondazione \u201cCasa Sollievo della Sofferenza\u201d, 71013 San Giovanni Rotondo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6992-5875","authenticated-orcid":false,"given":"Francesco","family":"Cocomazzi","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology & Endoscopy, IRCCS, Fondazione \u201cCasa Sollievo della Sofferenza\u201d, 71013 San Giovanni Rotondo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4704-8354","authenticated-orcid":false,"given":"Maria Rosa","family":"Valvano","sequence":"additional","affiliation":[{"name":"Quality and Accreditation Unit, IRCCS, Fondazione \u201cCasa Sollievo della Sofferenza\u201d, 71013 San Giovanni Rotondo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7038-3287","authenticated-orcid":false,"given":"Giuseppe","family":"Losurdo","sequence":"additional","affiliation":[{"name":"Section of Gastroenterology, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari, 70124 Bari, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2026-1200","authenticated-orcid":false,"given":"Alfredo","family":"Di Leo","sequence":"additional","affiliation":[{"name":"Section of Gastroenterology, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari, 70124 Bari, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8314-8016","authenticated-orcid":false,"given":"Francesco","family":"Perri","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology & Endoscopy, IRCCS, Fondazione \u201cCasa Sollievo della Sofferenza\u201d, 71013 San Giovanni Rotondo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,12,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1136\/gutjnl-2016-312288","article-title":"European Helicobacter and Microbiota Study Group and Consensus Panel: Guidelines for the management of Helicobacter pylori infection\u2014The Maastricht V\/Florence Consensus 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