{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T00:25:27Z","timestamp":1793406327072,"version":"4.5.0"},"reference-count":82,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2024,12,30]],"date-time":"2024-12-30T00:00:00Z","timestamp":1735516800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"MICIU\/AEI\/10.13039\/501100011033.","award":["PLEC2023-010275"],"award-info":[{"award-number":["PLEC2023-010275"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antibiotics"],"abstract":"<jats:p>Background\/Objectives: Antimicrobial resistance (AMR) in Enterococcus species from poultry production represents a significant public health threat due to the potential transmission of AMR through the food chain. This study aimed to examine the relative prevalence, resistance patterns, and mannitol fermentation capacity of Enterococcus isolates from various poultry production systems in Spain over a seven-year period (2017\u20132023). Methods: A total of 215 Enterococcus isolates were analyzed. Phenotypic assessments were conducted to determine resistance rates and metabolic capacities, while genotypic characterization focused on detecting vancomycin-resistance genes (vanA, vanB, vanC, and vanD). Results: Enterococcus faecalis (62.3%) and Enterococcus faecium (29.77%) were the predominant species, primarily isolated from broilers (74.88%), with the highest frequency observed in one-week-old chicks (31.16%). High resistance rates to tetracyclines and streptogramins were identified, while resistance to vancomycin (0.47%) and tigecycline (3.03%) was low. Interestingly, a significant reduction in tetracyclines resistance was shown in this period for Enterococcus faecalis (from 100% to 70% (2017\u20132023) and Enterococcus faecium (from 100% to 40% (2018\u20132023)). Multidrug resistance (MDR) was detected in 26.98% of isolates. Mannitol fermentation tests revealed high metabolic capacity in Enterococcus faecalis (99.25%) and Enterococcus faecium (96.88%), associated with adaptability and virulence potential. Genotypic analysis showed a very low prevalence of vanB and vanC genes. Conclusions: These findings highlight the critical need for targeted surveillance and intervention strategies in poultry production to mitigate the risks posed by MDR Enterococcus to public health.<\/jats:p>","DOI":"10.3390\/antibiotics14010016","type":"journal-article","created":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T07:34:19Z","timestamp":1735630459000},"page":"16","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Tracking the Prevalence of Antibiotic Resistance in Enterococcus Within the Spanish Poultry Industry: Insights from a One Health Approach"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-7939-3899","authenticated-orcid":false,"given":"Josep","family":"Garcia-Llorens","sequence":"first","affiliation":[{"name":"Centro de Calidad Av\u00edcola y Alimentaci\u00f3n Animal de la Comunidad Valenciana (CECAV), 12539 Alquerias del Ni\u00f1o Perdido, Spain"},{"name":"Food & Health Lab, Institute of Materials Science, University of Valencia, 46980 Valencia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1581-4811","authenticated-orcid":false,"given":"Isaac","family":"Monroy","sequence":"additional","affiliation":[{"name":"Centro de Calidad Av\u00edcola y Alimentaci\u00f3n Animal de la Comunidad Valenciana (CECAV), 12539 Alquerias del Ni\u00f1o Perdido, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3431-218X","authenticated-orcid":false,"given":"Jan","family":"Torres-Boncompte","sequence":"additional","affiliation":[{"name":"Centro de Calidad Av\u00edcola y Alimentaci\u00f3n Animal de la Comunidad Valenciana (CECAV), 12539 Alquerias del Ni\u00f1o Perdido, Spain"},{"name":"Food & Health Lab, Institute of Materials Science, University of Valencia, 46980 Valencia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2846-1311","authenticated-orcid":false,"given":"Jose","family":"Soriano","sequence":"additional","affiliation":[{"name":"Food & Health Lab, Institute of Materials Science, University of Valencia, 46980 Valencia, Spain"},{"name":"Joint Research Unit on Endocrinology, Nutrition and Clinical Dietetics, University of Valencia-Health Research Institute La Fe, 46026 Valencia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8298-102X","authenticated-orcid":false,"given":"Pablo","family":"Catal\u00e1-Gregori","sequence":"additional","affiliation":[{"name":"Centro de Calidad Av\u00edcola y Alimentaci\u00f3n Animal de la Comunidad Valenciana (CECAV), 12539 Alquerias del Ni\u00f1o Perdido, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2354-9800","authenticated-orcid":false,"given":"Sandra","family":"Sevilla-Navarro","sequence":"additional","affiliation":[{"name":"Centro de Calidad Av\u00edcola y Alimentaci\u00f3n Animal de la Comunidad Valenciana (CECAV), 12539 Alquerias del Ni\u00f1o Perdido, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,12,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e00058-18","DOI":"10.1128\/CMR.00058-18","article-title":"The Enterococcus: A Model of Adaptability to Its Environment","volume":"32","author":"Rice","year":"2019","journal-title":"Clin. 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