{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T05:21:00Z","timestamp":1765862460561,"version":"3.48.0"},"reference-count":25,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T00:00:00Z","timestamp":1765670400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005668","name":"Funda\u00e7\u00e3o de Apoio \u00e0 Pesquisa do Distrito Federal","doi-asserted-by":"crossref","award":["09\/2023\u2014Demanda Espont\u00e2nea"],"award-info":[{"award-number":["09\/2023\u2014Demanda Espont\u00e2nea"]}],"id":[{"id":"10.13039\/501100005668","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100005668","name":"Funda\u00e7\u00e3o de Apoio \u00e0 Pesquisa do Distrito Federal","doi-asserted-by":"crossref","award":["00193-00001858\/2023-30"],"award-info":[{"award-number":["00193-00001858\/2023-30"]}],"id":[{"id":"10.13039\/501100005668","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100005668","name":"Funda\u00e7\u00e3o de Apoio \u00e0 Pesquisa do Distrito Federal","doi-asserted-by":"crossref","award":["08\/2023\u2014Participa"],"award-info":[{"award-number":["08\/2023\u2014Participa"]}],"id":[{"id":"10.13039\/501100005668","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100005668","name":"Funda\u00e7\u00e3o de Apoio \u00e0 Pesquisa do Distrito Federal","doi-asserted-by":"crossref","award":["00193-00001809\/2023-05"],"award-info":[{"award-number":["00193-00001809\/2023-05"]}],"id":[{"id":"10.13039\/501100005668","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003593","name":"National Council for Scientific and Technological Development","doi-asserted-by":"crossref","award":["408339\/2023-3"],"award-info":[{"award-number":["408339\/2023-3"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antibiotics"],"abstract":"<jats:p>Background: Surface contamination in healthcare environments plays a key role in the persistence and transmission of microorganisms. Long-lasting antimicrobial coatings based on copper\u2013polymer complexes offer a promising passive strategy to minimize environmental contamination and healthcare-associated infections. Methods: This study evaluated a copper-alloy polymeric tape through physicochemical, in vitro, and hospital-based assessments. Structural analyses (XRD, Raman, SEM, EDX) were used to characterize the material, while antimicrobial efficacy was determined against Gram-positive and Gram-negative bacteria following ISO 22196:2011. A randomized 19-week clinical study was conducted in the Emergency and Urgent Unit of the University Hospital of Bras\u00edlia to quantify microbial loads on high-touch surfaces covered with the copper-alloy tape or a non-antimicrobial control. Results: Structural characterization techniques validated the integrity and heterogeneous distribution of copper within the polymeric matrix. All tested bacterial strains exhibited complete growth inhibition on the copper-alloy tape, with final counts consistently below the detection threshold (&lt;1.00 log10 CFU\/mL). Human keratinocytes analyzed by SEM showed preserved morphology. In hospital conditions, treated surfaces maintained significantly lower microbial loads than controls over 19 weeks. The number of yeast-positive samples was small compared to the total number of samples collected during the study, but Candida parapsilosis was the most frequently identified species. Conclusions: These findings support its use as a sustainable intervention to reduce environmental contamination and infection risks in healthcare settings.<\/jats:p>","DOI":"10.3390\/antibiotics14121262","type":"journal-article","created":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T09:36:39Z","timestamp":1765791399000},"page":"1262","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Antimicrobial Activity and Characterization of a Validated Copper-Complexed Polymer Tape for Surface Disinfectant Applications"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9651-1598","authenticated-orcid":false,"given":"Andreanne G.","family":"Vasconcelos","sequence":"first","affiliation":[{"name":"People&Science Pesquisa Desenvolvimento e Inova\u00e7\u00e3o Ltda, Centro de Apoio ao Desenvolvimento Tecnol\u00f3gico (CDT), University of Bras\u00edlia (UnB), Bras\u00edlia 70910-900, DF, Brazil"},{"name":"Research Center in Applied Morphology and Immunology (NuPMIA), Faculty of Medicine, University of Bras\u00edlia (UnB), Bras\u00edlia 70910-900, DF, Brazil"},{"name":"Centro Universit\u00e1rio do Distrito Federal (UDF), Bras\u00edlia 70390-045, DF, Brazil"},{"name":"The Bridge, University of Lincoln, Joseph Ruston Building, Lincoln LN6 7EL, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William D.","family":"Amorim","sequence":"additional","affiliation":[{"name":"Centro Universit\u00e1rio do Distrito Federal (UDF), Bras\u00edlia 70390-045, DF, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3644-4792","authenticated-orcid":false,"given":"Bruno S.","family":"S\u00e1","sequence":"additional","affiliation":[{"name":"Research Center in Applied Morphology and Immunology (NuPMIA), Faculty of Medicine, University of Bras\u00edlia (UnB), Bras\u00edlia 70910-900, DF, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luan B. V.","family":"Costa","sequence":"additional","affiliation":[{"name":"Research Center in Applied Morphology and Immunology (NuPMIA), Faculty of Medicine, University of Bras\u00edlia (UnB), Bras\u00edlia 70910-900, DF, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gustavo S. de","family":"Araujo","sequence":"additional","affiliation":[{"name":"Programa de P\u00f3s-Gradua\u00e7\u00e3o em Patologia Molecular, Faculty of Medicine, University of Bras\u00edlia (UnB), Bras\u00edlia 70910-900, DF, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6141-2362","authenticated-orcid":false,"given":"Helder Andrey R.","family":"Gomes","sequence":"additional","affiliation":[{"name":"Centro Universit\u00e1rio do Distrito Federal (UDF), Bras\u00edlia 70390-045, DF, Brazil"},{"name":"Laborat\u00f3rio Central de Sa\u00fade P\u00fablica (LACEN-DF), Bras\u00edlia 70830-010, DF, 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