{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T14:59:31Z","timestamp":1780066771496,"version":"3.54.0"},"reference-count":39,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T00:00:00Z","timestamp":1768953600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002848","name":"Agencia Nacional de Investigaci\u00f3n y Desarrollo, ANID","doi-asserted-by":"publisher","award":["1231676"],"award-info":[{"award-number":["1231676"]}],"id":[{"id":"10.13039\/501100002848","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Programa de Apoyo e Incentivo a las publicaciones at PUCV"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antibiotics"],"abstract":"<jats:p>Background\/Objectives: The genus Tristerix comprises at least ten species, found from southern Chile to Colombia in South America. In Chile, several species of these hemiparasitic plants are known as quitral or quintral. Quitral, mainly T. corymbosus (syn. T. tetrandus), is used in alternative medicine for its anti-inflammatory, digestive, hemostatic, hypocholesterolemic, and wound-healing properties. This study investigates the phytochemical composition and antimicrobial properties of T. corymbosus. Methods: A hydroalcoholic extract of T. corymbosus was prepared from leaves and small branches. The addition of methanol, on the extract, produced precipitation allowing us to isolate a methanol-soluble fraction, a brown powder obtained after filtration, and a tar-like residue remaining in the flask. These fractions were resuspended and tested for antimicrobial activity. Results: All fractions showed activity against Streptococcus pyogenes, but not E. coli. The brown powder exhibits the strongest potency against Gram-positive bacteria, some Gram-negative and C. albicans. HPLC-MS analysis revealed presence of lipidic compounds with surfactant properties. Conclusions: The abundant lipidic molecules present in the analyzed fraction likely account for the antimicrobial effects through affecting membrane structure of microorganisms supporting the traditional wound-healing uses of T. corymbosus in ancestral medicine.<\/jats:p>","DOI":"10.3390\/antibiotics15010105","type":"journal-article","created":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T11:11:17Z","timestamp":1768993877000},"page":"105","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Phytochemical Characterization and Antimicrobial Properties of a Hydroalcoholic Extract of Tristerix corymbosus (L) Kuijt, a Chilean Mistletoe Species Hosted on Salix babylonica (L)"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7788-3185","authenticated-orcid":false,"given":"Alejandro A.","family":"Hidalgo","sequence":"first","affiliation":[{"name":"Escuela de Qu\u00edmica y Farmacia, Facultad de Medicina, Universidad Andres Bello, Santiago 8370134, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5811-2433","authenticated-orcid":false,"given":"Sergio A.","family":"Bucarey","sequence":"additional","affiliation":[{"name":"Departamento de Ciencias Biol\u00f3gicas Animales, Facultad de Ciencias Veterinarias y Pecuarias, Universidad de Chile, Santiago 8820808, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatriz","family":"Sep\u00falveda","sequence":"additional","affiliation":[{"name":"Departamento de Ciencias Qu\u00edmicas, Facultad de Ciencias Exactas, Universidad Andres Bello, Santiago 8370134, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-5540-0992","authenticated-orcid":false,"given":"Sebasti\u00e1n","family":"Cumsille-Escandar","sequence":"additional","affiliation":[{"name":"Escuela de Qu\u00edmica y Farmacia, Facultad de Medicina, Universidad Andres Bello, Santiago 8370134, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9226-7033","authenticated-orcid":false,"given":"Alejandro","family":"Charmell","sequence":"additional","affiliation":[{"name":"Escuela de Qu\u00edmica y Farmacia, Facultad de Medicina, Universidad Andres Bello, Santiago 8370134, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7446-1932","authenticated-orcid":false,"given":"Nicol\u00e1s A.","family":"Villagra","sequence":"additional","affiliation":[{"name":"Departamento de Ciencias Biol\u00f3gicas, Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago 8370134, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4375-4155","authenticated-orcid":false,"given":"Andr\u00e9s","family":"Barriga","sequence":"additional","affiliation":[{"name":"Centro de Estudios Para el Desarrollo de la Qu\u00edmica (CEPEDEQ), Facultad de Ciencias Qu\u00edmicas y, Farmac\u00e9uticas, Universidad de Chile, Santiago 8380492, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-8843-1828","authenticated-orcid":false,"given":"Consuelo F.","family":"Mart\u00ednez-Contreras","sequence":"additional","affiliation":[{"name":"Escuela de Qu\u00edmica y Farmacia, Facultad de Medicina, Universidad Andres Bello, Santiago 8370134, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2879-0126","authenticated-orcid":false,"given":"Jorge","family":"Escobar","sequence":"additional","affiliation":[{"name":"Laboratorio de Qu\u00edmica Biol\u00f3gica, Facultad de Ciencias, Pontificia Universidad Cat\u00f3lica de Valpara\u00edso, Valpara\u00edso 2340000, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0177-4847","authenticated-orcid":false,"given":"Jos\u00e9 L.","family":"Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Departamento de Ingenier\u00eda Metal\u00fargica, Facultad de Ingenier\u00eda, Universidad de Santiago de Chile, Estaci\u00f3n Central, Santiago 9160000, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4165-8461","authenticated-orcid":false,"given":"Mait\u00e9","family":"Rodr\u00edguez-D\u00edaz","sequence":"additional","affiliation":[{"name":"Departamento de Qu\u00edmica, Escuela de Qu\u00edmica, Facultad de Ciencias Naturales, Matem\u00e1tica y del Medio Ambiente, Universidad Tecnol\u00f3gica Metropolitana, Santiago 7800003, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,1,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"4645","DOI":"10.4067\/S0717-97072019000404645","article-title":"Determination of Reducing Power and Phytochemical Profile of the Chilean Mistletoe \u201cQuintral\u201d (Tristerix corymbosus (L) Kuijt) Hosted in \u201cMaqui\u201d (Aristotelia chilensis), \u201cHuay\u00fan\u201d (Rhaphitamnus spinosus) and \u201cPoplar\u201d (Populus nigra)","volume":"64","author":"Torres","year":"2019","journal-title":"J. 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