{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T17:02:02Z","timestamp":1786122122467,"version":"build-2736575974"},"reference-count":30,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T00:00:00Z","timestamp":1786060800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antibiotics"],"abstract":"<jats:p>Background: Candidozyma auris (Candida auris) is an emerging multidrug-resistant fungal pathogen that can cause hospital outbreaks and is associated with high mortality. However, data on the clinical predictors of mortality in patients with bloodstream infection (BSI) caused by C. auris remain limited, particularly in Latin America, and the impact of guideline-based management practices on clinical outcomes has been scarcely explored. Methods: We conducted a multicenter retrospective cohort study including 134 patients with culture-proven C. auris BSI admitted to seven hospitals in Colombia between 2016 and 2021. Demographic, clinical, and therapeutic variables were evaluated to identify factors associated with 30-day mortality using a multivariate logistic regression model. Variables related to quality of care and guideline-based candidemia management, included in the EQUAL Candida Score, were also assessed. Results: The thirty-day mortality rate was 38.1%. In the multivariate analysis, older age (OR per decade: 1.37; 95% CI: 1.07\u20131.78), prior corticosteroid therapy (OR: 4.06; 95% CI: 1.70\u201310.16), and shock within 48 h of BSI (OR: 6.22; 95% CI: 2.52\u201316.52) were associated with higher mortality. Conversely, a higher EQUAL Candida Score was associated with lower 30-day mortality (OR: 0.84; 95% CI: 0.73\u20130.97). Conclusions: In this large Colombian cohort, advanced age, corticosteroid exposure, and early hemodynamic instability were significant predictors of mortality in patients with C. auris BSI. Greater adherence to recommended management practices\u2014as reflected by the EQUAL Candida Score\u2014appeared to be associated with lower mortality, underscoring the potential role of timely, structured care strategies in improving outcomes for patients with C. auris infections. To the best of our knowledge, this study is the first to evaluate the EQUAL Candida Score in a cohort of patients with C. auris BSI.<\/jats:p>","DOI":"10.3390\/antibiotics15080758","type":"journal-article","created":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T08:01:36Z","timestamp":1786089696000},"page":"758","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Risk Factors for Mortality Among Patients with Bloodstream Infection Caused by Candidozyma auris in Colombia"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8798-6690","authenticated-orcid":false,"given":"Mariana","family":"Pimiento-D\u00edaz","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Faculty of Medicine, Universidad Nacional de Colombia, Sede Bogot\u00e1 111321, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynthia","family":"Ortiz-Roa","sequence":"additional","affiliation":[{"name":"Subred Integrada de Servicios de Salud Norte E.S.E. Hospital Sim\u00f3n Bol\u00edvar, Bogot\u00e1 111221, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebasti\u00e1n Felipe","family":"Sierra-Uma\u00f1a","sequence":"additional","affiliation":[{"name":"Subred Integrada de Servicios de Salud Sur E.S.E. Hospital Tunal, Bogot\u00e1 110621, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Yesid","family":"Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Cl\u00ednica Integral de Emergencias Laura Daniela, Facultad de Ciencias M\u00e9dicas y de la Salud, Instituto Cardiovascular del Cesar, Centro de Investigaciones Microbiol\u00f3gicas del Cesar (CIMCE), Universidad de Santander, Valledupar 200001, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerardo Antonio","family":"Mu\u00f1et\u00f3n-L\u00f3pez","sequence":"additional","affiliation":[{"name":"Subred Integrada de Servicios de Salud Suroccidente E.S.E. Hospital de Kennedy, Bogot\u00e1 110871, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0530-7066","authenticated-orcid":false,"given":"Carlos Augusto","family":"Sol\u00f3rzano-Ramos","sequence":"additional","affiliation":[{"name":"Subred Integrada de Servicios de Salud Suroccidente E.S.E. Hospital de Kennedy, Bogot\u00e1 110871, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3029-118X","authenticated-orcid":false,"given":"Patricia","family":"Escand\u00f3n","sequence":"additional","affiliation":[{"name":"Grupo de Microbiolog\u00eda, Instituto Nacional de Salud, Bogot\u00e1 111321, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5419-4494","authenticated-orcid":false,"given":"Carlos Arturo","family":"\u00c1lvarez-Moreno","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Faculty of Medicine, Universidad Nacional de Colombia, Sede Bogot\u00e1 111321, Colombia"},{"name":"Cl\u00ednica Universitaria Colombia, Cl\u00ednica Colsanitas, Bogot\u00e1 111321, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0882-9652","authenticated-orcid":false,"given":"Jorge Alberto","family":"Cort\u00e9s","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Faculty of Medicine, Universidad Nacional de Colombia, Sede Bogot\u00e1 111321, Colombia"},{"name":"Infectious Diseases Unit, Hospital Universitario Nacional, Bogoot\u00e1 111321, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,8,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1924","DOI":"10.1056\/NEJMra2402635","article-title":"Candida auris Infections","volume":"391","author":"Lionakis","year":"2024","journal-title":"N. 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