{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T04:18:20Z","timestamp":1760242700499,"version":"build-2065373602"},"reference-count":70,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2016,2,15]],"date-time":"2016-02-15T00:00:00Z","timestamp":1455494400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antibiotics"],"abstract":"<jats:p>Antimicrobial stewardship programs (ASPs) focus on improving the utilization of broad spectrum antibiotics to decrease the incidence of multidrug-resistant Gram positive and Gram negative pathogens. Hospital admission for both medical and surgical intra-abdominal infections (IAIs) commonly results in the empiric use of broad spectrum antibiotics such as fluoroquinolones, beta-lactam beta-lactamase inhibitors, and carbapenems that can select for resistant organisms. This review will discuss the management of uncomplicated and complicated IAIs as well as highlight stewardship initiatives focusing on the proper use of broad spectrum antibiotics.<\/jats:p>","DOI":"10.3390\/antibiotics5010011","type":"journal-article","created":{"date-parts":[[2016,2,15]],"date-time":"2016-02-15T06:23:07Z","timestamp":1455517387000},"page":"11","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Treatment Modalities and Antimicrobial Stewardship Initiatives in the Management of Intra-Abdominal Infections"],"prefix":"10.3390","volume":"5","author":[{"given":"Charles","family":"Hoffmann","sequence":"first","affiliation":[{"name":"Wegmans School of Pharmacy, St. John Fisher College, Rochester, NY 14618, USA"},{"name":"Department of Pharmacy, University of Rochester Medical Center, Rochester, NY 14642, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Zak","sequence":"additional","affiliation":[{"name":"Wegmans School of Pharmacy, St. John Fisher College, Rochester, NY 14618, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Avery","sequence":"additional","affiliation":[{"name":"Wegmans School of Pharmacy, St. John Fisher College, Rochester, NY 14618, USA"},{"name":"St. Joseph\u2019s Hospital Health Center, Syracuse, NY 13203, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jack","family":"Brown","sequence":"additional","affiliation":[{"name":"Wegmans School of Pharmacy, St. John Fisher College, Rochester, NY 14618, USA"},{"name":"Department of Pharmacy, University of Rochester Medical Center, Rochester, NY 14642, USA"},{"name":"Department of Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2016,2,15]]},"reference":[{"key":"ref_1","first-page":"694","article-title":"Updated guideline on diagnosis and treatment of intra-abdominal infections","volume":"82","author":"Armstrong","year":"2010","journal-title":"Am. 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