{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T19:52:49Z","timestamp":1778010769844,"version":"3.51.4"},"reference-count":43,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2019,11,28]],"date-time":"2019-11-28T00:00:00Z","timestamp":1574899200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antibiotics"],"abstract":"<jats:p>The objective of this work was to evaluate the phytochemical composition and the antibacterial and antibiotic-modulating activities of the essential oils of Eugenia brasiliensis Lam (OEEb) and Piper mosenii C. DC (OEPm) singly or in association with blue LED (Light-emitting diode) light. The antibacterial and antibiotic-modulatory activities of the essential oils on the activity of aminoglycosides were evaluated to determine the minimum inhibitory concentration (MIC, \u03bcg\/mL) in the presence or absence of exposure to blue LED light. The chemical analysis showed \u03b1-pinene and bicyclogermacrene as major constituents of OEPm, whereas \u03b1-muurolol was the main compound of OEEb. Both OEEb and OEPm showed MIC \u2265 512 \u03bcg\/mL against the strains under study. However, the association of these oils with the blue LED light enhanced the action of the aminoglycosides amikacin and gentamicin. In conclusion, the association of aminoglycosides with the blue LED light and essential oils was effective against resistant bacteria.<\/jats:p>","DOI":"10.3390\/antibiotics8040242","type":"journal-article","created":{"date-parts":[[2019,11,28]],"date-time":"2019-11-28T10:54:10Z","timestamp":1574938450000},"page":"242","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Photoinduced Antibacterial Activity of the Essential Oils from Eugenia brasiliensis Lam and Piper mosenii C. DC. by Blue Led Light"],"prefix":"10.3390","volume":"8","author":[{"given":"Rakel Olinda","family":"Macedo da Silva","sequence":"first","affiliation":[{"name":"Department of Biomedicine, University Center Dr. Le\u00e3o Sampaio, Juazeiro do Norte 63040-005, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Walber","family":"Gon\u00e7alves Castro","sequence":"additional","affiliation":[{"name":"Department of Biomedicine, University Center Dr. Le\u00e3o Sampaio, Juazeiro do Norte 63040-005, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Orlando","family":"de Menezes Dantas Junior","sequence":"additional","affiliation":[{"name":"Department of Biomedicine, University Center Dr. Le\u00e3o Sampaio, Juazeiro do Norte 63040-005, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Carolina","family":"Justino de Ara\u00fajo","sequence":"additional","affiliation":[{"name":"Department of Biological Chemistry, Regional University of Cariri, Crato 63105-000, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Karollyna","family":"do Nascimento Silva Leandro","sequence":"additional","affiliation":[{"name":"Department of Biomedicine, University Center Dr. Le\u00e3o Sampaio, Juazeiro do Norte 63040-005, Brazil"},{"name":"Department of Biological Chemistry, Regional University of Cariri, Crato 63105-000, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ra\u00edra Justino","family":"Oliveira Costa","sequence":"additional","affiliation":[{"name":"Department of Biomedicine, University Center Dr. Le\u00e3o Sampaio, Juazeiro do Norte 63040-005, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luciely","family":"Leite Pinto","sequence":"additional","affiliation":[{"name":"Department of Biomedicine, University Center Dr. Le\u00e3o Sampaio, Juazeiro do Norte 63040-005, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00edvia Maria","family":"Garcia Leandro","sequence":"additional","affiliation":[{"name":"Department of Biomedicine, University Center Dr. Le\u00e3o Sampaio, Juazeiro do Norte 63040-005, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2332-3553","authenticated-orcid":false,"given":"Luiz E. da","family":"Silva","sequence":"additional","affiliation":[{"name":"Setor Litoral, Federal University of Paran\u00e1, Curitiba 80.060-000, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wanderlei","family":"do Amaral","sequence":"additional","affiliation":[{"name":"Setor Litoral, Federal University of Paran\u00e1, Curitiba 80.060-000, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucas D.","family":"Parabocz","sequence":"additional","affiliation":[{"name":"Setor Litoral, Federal University of Paran\u00e1, Curitiba 80.060-000, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aurea P.","family":"Ferriani","sequence":"additional","affiliation":[{"name":"Setor Litoral, Federal University of Paran\u00e1, Curitiba 80.060-000, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruna","family":"Garcia","sequence":"additional","affiliation":[{"name":"Setor Litoral, Federal University of Paran\u00e1, Curitiba 80.060-000, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beatriz H. L. N.","family":"Sales Maia","sequence":"additional","affiliation":[{"name":"Setor Litoral, Federal University of Paran\u00e1, Curitiba 80.060-000, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jana\u00edna","family":"Esmeraldo Rocha","sequence":"additional","affiliation":[{"name":"Department of Biological Chemistry, Regional University of Cariri, Crato 63105-000, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camila","family":"Fonseca Bezerra","sequence":"additional","affiliation":[{"name":"Department of Biological Chemistry, Regional University of Cariri, Crato 63105-000, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thiago","family":"Sampaio de Freitas","sequence":"additional","affiliation":[{"name":"Department of Biological Chemistry, Regional University of Cariri, Crato 63105-000, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Socorro Costa","sequence":"additional","affiliation":[{"name":"Department of Biological Chemistry, Regional University of Cariri, Crato 63105-000, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F\u00e1bia","family":"Ferreira Campina","sequence":"additional","affiliation":[{"name":"Department of Biological Chemistry, Regional University of Cariri, Crato 63105-000, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edinardo Fagner","family":"Ferreira Matias","sequence":"additional","affiliation":[{"name":"Department of Biomedicine, University Center Dr. Le\u00e3o Sampaio, Juazeiro do Norte 63040-005, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5063-1236","authenticated-orcid":false,"given":"Marcello","family":"Iriti","sequence":"additional","affiliation":[{"name":"Department of Agricultural and Environmental Sciences, Milan State University, via G. 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