{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T00:04:05Z","timestamp":1779926645297,"version":"3.53.1"},"reference-count":62,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2020,3,31]],"date-time":"2020-03-31T00:00:00Z","timestamp":1585612800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antibiotics"],"abstract":"<jats:p>Antimicrobial resistance is a global issue that threatens the effective practice of modern medicine and global health. The emergence of multidrug-resistant (MDR) fungal strains of Candida auris and azole-resistant Aspergillus fumigatus were highlighted in the Centers for Disease Control and Prevention\u2019s (CDC) 2019 report, Antibiotic Resistance Threats in the United States. Conventional antifungals used to treat fungal infections are no longer as effective, leading to increased mortality. Compounding this issue, there are very few new antifungals currently in development. Plants from traditional medicine represent one possible research path to addressing the issue of MDR fungal pathogens. In this commentary piece, we discuss how medical ethnobotany\u2014the study of how people use plants in medicine\u2014can be used as a guide to identify plant species for the discovery and development of novel antifungal therapies.<\/jats:p>","DOI":"10.3390\/antibiotics9040150","type":"journal-article","created":{"date-parts":[[2020,3,31]],"date-time":"2020-03-31T13:27:19Z","timestamp":1585661239000},"page":"150","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Prevalence and Therapeutic Challenges of Fungal Drug Resistance: Role for Plants in Drug Discovery"],"prefix":"10.3390","volume":"9","author":[{"given":"Lewis","family":"Marquez","sequence":"first","affiliation":[{"name":"Molecular and Systems Pharmacology, Emory University, Atlanta, GA 30322, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9615-7886","authenticated-orcid":false,"given":"Cassandra L.","family":"Quave","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Center for the Study of Human Health, Emory University, Atlanta, GA 30322, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,3,31]]},"reference":[{"key":"ref_1","unstructured":"Department of Health and Human Services (2019). 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