{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T17:13:51Z","timestamp":1789578831071,"version":"build-2803163510"},"reference-count":22,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2020,10,29]],"date-time":"2020-10-29T00:00:00Z","timestamp":1603929600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antibiotics"],"abstract":"<jats:p>Actinomycosis is a chronic bacterial infection characterized by continuous local spread, irrespective of anatomical barriers, and granulomatous suppurative inflammation. Due to its expansive local growth, it can simulate a malignant tumour. Subsequent hematogenous dissemination to distant organs can mimic metastases and further increase suspicion for malignancy. A case of severe disseminated pelvic actinomycosis associated with intrauterine device is described here. The patient presented with a pelvic mass mimicking a tumour, bilateral ureteral obstruction, ascites, multinodular involvement of the liver, lungs and spleen, inferior vena cava thrombosis and extreme cachexia. Actinomycosis was diagnosed by liver biopsy and confirmed by culture of Actinomyces naeslundii from extracted intrauterine contraceptive device (IUD). Prolonged treatment with aminopenicillin and surgery resulted in recovery with moderate sequelae.<\/jats:p>","DOI":"10.3390\/antibiotics9110748","type":"journal-article","created":{"date-parts":[[2020,10,29]],"date-time":"2020-10-29T09:44:53Z","timestamp":1603964693000},"page":"748","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Disseminated Pelvic Actinomycosis Caused by Actinomyces Naeslundii"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7535-6210","authenticated-orcid":false,"given":"Olga","family":"D\u017eupov\u00e1","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases, Third Faculty of Medicine, Charles University, 100 00 Prague, Czech Republic"},{"name":"Department of Infectious Diseases, Hospital Na Bulovce, 100 81 Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6649-8292","authenticated-orcid":false,"given":"Jana","family":"Kulichov\u00e1","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Hospital Na Bulovce, 100 81 Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji\u0159\u00ed","family":"Bene\u0161","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Third Faculty of Medicine, Charles University, 100 00 Prague, Czech Republic"},{"name":"Department of Infectious Diseases, Hospital Na Bulovce, 100 81 Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,10,29]]},"reference":[{"key":"ref_1","first-page":"3071","article-title":"Agents of Actinomycosis","volume":"Volume 2","author":"Bennett","year":"2020","journal-title":"Mandell, Douglas, and Bennett\u00b4s Principles and Practice of Infectious Diseases"},{"key":"ref_2","first-page":"e2721","article-title":"Rare abdominopelvic Actinomycosis causing an intestinal band obstruction and mimicking an ovarian malignancy","volume":"10","author":"Kandhasamy","year":"2018","journal-title":"Cureus"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"555","DOI":"10.3349\/ymj.2009.50.4.555","article-title":"Clinical features of abdominopelvic Actinomycosis: Report of twenty cases and literature review","volume":"50","author":"Choi","year":"2009","journal-title":"Yonsei Med. 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