{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:31:48Z","timestamp":1787027508434,"version":"build-2736575974"},"reference-count":134,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2022,12,18]],"date-time":"2022-12-18T00:00:00Z","timestamp":1671321600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Shandong University of Technology"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antioxidants"],"abstract":"<jats:p>As people are paying more and more attention to dental health, various dental treatment procedures have emerged, such as tooth bleaching, dental implants, and dental restorations. However, a large number of free radicals are typically produced during the dental procedures. When the imbalance in distribution of reactive oxygen species (ROS) is induced, oxidative stress coupled with oxidative damage occurs. Oral inflammations such as those in periodontitis and pulpitis are also unavoidable. Therefore, the applications of exogenous antioxidants in oral environment have been proposed. In this article, the origin of ROS during dental procedures, the types of antioxidants, and their working mechanisms are reviewed. Additionally, antioxidants delivery in the complicated dental procedures and their feasibility for clinical applications are also covered. Finally, the importance of safety assessment of these materials and future work to take the challenge in antioxidants development are proposed for perspective.<\/jats:p>","DOI":"10.3390\/antiox11122492","type":"journal-article","created":{"date-parts":[[2022,12,19]],"date-time":"2022-12-19T06:58:29Z","timestamp":1671433109000},"page":"2492","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Applications of Antioxidants in Dental Procedures"],"prefix":"10.3390","volume":"11","author":[{"given":"Fan","family":"Qi","sequence":"first","affiliation":[{"name":"School of Chemistry and Chemical Engineering, Shandong University of Technology, 266 Xincun Road, Zibo 255000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haofei","family":"Huang","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering, Shandong University of Technology, 266 Xincun Road, Zibo 255000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering, Shandong University of Technology, 266 Xincun Road, Zibo 255000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weifeng","family":"Rong","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering, Shandong University of Technology, 266 Xincun Road, Zibo 255000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3405-1765","authenticated-orcid":false,"given":"Jing","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering, Shandong University of Technology, 266 Xincun Road, Zibo 255000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.cden.2007.12.002","article-title":"Patient-and population-reported outcomes in public health dentistry: Oral health-related quality of life","volume":"52","author":"Rozier","year":"2008","journal-title":"Dent. 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