{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T11:31:17Z","timestamp":1791718277809,"version":"4.3.4"},"reference-count":32,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2023,1,7]],"date-time":"2023-01-07T00:00:00Z","timestamp":1673049600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Key Project of Regional Innovation and Development Joint Fund of National Natural Science Foundation of China","award":["U20A2056"],"award-info":[{"award-number":["U20A2056"]}]},{"name":"Key Project of Regional Innovation and Development Joint Fund of National Natural Science Foundation of China","award":["2019RS3022"],"award-info":[{"award-number":["2019RS3022"]}]},{"name":"Key Project of Regional Innovation and Development Joint Fund of National Natural Science Foundation of China","award":["2020PB0097"],"award-info":[{"award-number":["2020PB0097"]}]},{"name":"Industry and Research Talent Support Project from Wang Kuancheng of the Chinese Academy of Sciences, Special Funds for Construction of Innovative Provinces in Hunan Province","award":["U20A2056"],"award-info":[{"award-number":["U20A2056"]}]},{"name":"Industry and Research Talent Support Project from Wang Kuancheng of the Chinese Academy of Sciences, Special Funds for Construction of Innovative Provinces in Hunan Province","award":["2019RS3022"],"award-info":[{"award-number":["2019RS3022"]}]},{"name":"Industry and Research Talent Support Project from Wang Kuancheng of the Chinese Academy of Sciences, Special Funds for Construction of Innovative Provinces in Hunan Province","award":["2020PB0097"],"award-info":[{"award-number":["2020PB0097"]}]},{"name":"Chinese Academy of Sciences President\u2019s International Fellowship Initiative","award":["U20A2056"],"award-info":[{"award-number":["U20A2056"]}]},{"name":"Chinese Academy of Sciences President\u2019s International Fellowship Initiative","award":["2019RS3022"],"award-info":[{"award-number":["2019RS3022"]}]},{"name":"Chinese Academy of Sciences President\u2019s International Fellowship Initiative","award":["2020PB0097"],"award-info":[{"award-number":["2020PB0097"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antioxidants"],"abstract":"<jats:p>Adequate crude protein (CP) levels in diets play potential roles in swine production. This study determined the impacts of different CP levels on the antioxidant capacity of pigs during different body weight (BW) stages. Three hundred and sixty Huanjiang mini-pigs were allocated to one of three independent experiments, including a 5\u201310 kg BW group, where CP levels included 14%, 16%, 18%, 20%, and 22%; a 10\u201320 kg BW group, where CP levels included 12%, 14%, 16%, 18%, and 20%; and a 20\u201330 kg BW group, where CP levels included 10%, 12%, 14%, 16%, and 18%. These independent experiments were conducted for 28, 28, and 26 days, respectively. Results showed that the 20% CP level increased (p &lt; 0.05) the plasma CAT and GSH-Px activities and the GSH concentration of pigs than in the pigs supplemented with the 14\u201318% CP levels, and the 20% CP level up-regulated (p &lt; 0.05) the ileal oxidative stress-related gene expression levels of pigs than in the pigs supplemented with the 14% CP level at the 5\u201310 kg BW. In addition, diets supplemented with 18% CP level increased (p &lt; 0.05) the ileal GSH concentration of pigs than in the pigs supplemented with the 14% and 20% CP levels, and the 16\u201318% CP levels increased (p &lt; 0.05) the jejunal SOD activity of pigs than in the pigs supplemented with the 14% CP level. At 10\u201320 kg BW, the 16% CP level presented the strongest jejunal and ileal antioxidant capacity, the 18% CP level had the lowest plasma concentrations of MDA and highest GSH, and the 14\u201316% CP levels increased the plasma CAT and SOD activities (p &lt; 0.05). Moreover, the 16\u201320% CP levels up-regulated (p &lt; 0.05) the oxidative stress-related gene expression levels. At 20\u201330 kg BW, diets supplemented with the 16% CP level increased the plasma CAT activity of pigs than in the pigs supplemented with the 12\u201314% CP levels, and the 14\u201316% CP levels decreased the MDA concentration compared with the 10% CP levels (p &lt; 0.05). In conclusion, these findings indicate adequate CP levels of 20%, 16%, and 14% for Huanjiang mini-pigs at the 5\u201310, 10\u201320, and 20\u201330 kg BW stages, respectively.<\/jats:p>","DOI":"10.3390\/antiox12010148","type":"journal-article","created":{"date-parts":[[2023,1,9]],"date-time":"2023-01-09T02:31:30Z","timestamp":1673231490000},"page":"148","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Dietary Protein Levels Modulate the Antioxidant Capacity during Different Growth Stages in Huanjiang Mini-Pigs"],"prefix":"10.3390","volume":"12","author":[{"given":"Yating","family":"Liu","sequence":"first","affiliation":[{"name":"Key Laboratory of Agro-Ecological Processes in Subtropical Region, Hunan Provincial Key Laboratory of Animal Nutritional Physiology and Metabolic Process, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China"},{"name":"College of Advanced Agricultural Sciences, University of Chinese Academy of Sciences, Beijing 100008, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0118-5708","authenticated-orcid":false,"given":"Md. Abul Kalam","family":"Azad","sequence":"additional","affiliation":[{"name":"Key Laboratory of Agro-Ecological Processes in Subtropical Region, Hunan Provincial Key Laboratory of Animal Nutritional Physiology and Metabolic Process, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China"},{"name":"College of Advanced Agricultural Sciences, University of Chinese Academy of Sciences, Beijing 100008, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xichen","family":"Zhao","sequence":"additional","affiliation":[{"name":"Key Laboratory of Agro-Ecological Processes in Subtropical Region, Hunan Provincial Key Laboratory of Animal Nutritional Physiology and Metabolic Process, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Zhu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Agro-Ecological Processes in Subtropical Region, Hunan Provincial Key Laboratory of Animal Nutritional Physiology and Metabolic Process, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China"},{"name":"College of Advanced Agricultural Sciences, University of Chinese Academy of Sciences, Beijing 100008, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8034-6682","authenticated-orcid":false,"given":"Xiangfeng","family":"Kong","sequence":"additional","affiliation":[{"name":"Key Laboratory of Agro-Ecological Processes in Subtropical Region, Hunan Provincial Key Laboratory of Animal Nutritional Physiology and Metabolic Process, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China"},{"name":"College of Advanced Agricultural Sciences, University of Chinese Academy of Sciences, Beijing 100008, China"},{"name":"Research Center of Mini-Pig, Huanjiang Observation and Research Station for Karst Ecosystems, Chinese Academy of Sciences, Huanjiang 547100, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,1,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"427318","DOI":"10.1155\/2014\/427318","article-title":"Oxidative stress in alzheimer\u2019s disease: Why did antioxidant therapy fail?","volume":"2014","author":"Persson","year":"2014","journal-title":"Oxid. 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