{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T18:09:59Z","timestamp":1790359799816,"version":"4.1.0"},"reference-count":105,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2023,1,24]],"date-time":"2023-01-24T00:00:00Z","timestamp":1674518400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100011011","name":"Andalusian Government","doi-asserted-by":"publisher","award":["2021\/CTS-1074"],"award-info":[{"award-number":["2021\/CTS-1074"]}],"id":[{"id":"10.13039\/501100011011","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011011","name":"Andalusian Government","doi-asserted-by":"publisher","award":["BES-2012-056104"],"award-info":[{"award-number":["BES-2012-056104"]}],"id":[{"id":"10.13039\/501100011011","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011011","name":"Andalusian Government","doi-asserted-by":"publisher","award":["US-1381492"],"award-info":[{"award-number":["US-1381492"]}],"id":[{"id":"10.13039\/501100011011","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Andalusian Government","award":["2021\/CTS-1074"],"award-info":[{"award-number":["2021\/CTS-1074"]}]},{"name":"Andalusian Government","award":["BES-2012-056104"],"award-info":[{"award-number":["BES-2012-056104"]}]},{"name":"Andalusian Government","award":["US-1381492"],"award-info":[{"award-number":["US-1381492"]}]},{"name":"Andalusian Plan for Research, Development, and Innovation 2020 from the European Regional Development Fund (ERDF)","award":["2021\/CTS-1074"],"award-info":[{"award-number":["2021\/CTS-1074"]}]},{"name":"Andalusian Plan for Research, Development, and Innovation 2020 from the European Regional Development Fund (ERDF)","award":["BES-2012-056104"],"award-info":[{"award-number":["BES-2012-056104"]}]},{"name":"Andalusian Plan for Research, Development, and Innovation 2020 from the European Regional Development Fund (ERDF)","award":["US-1381492"],"award-info":[{"award-number":["US-1381492"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antioxidants"],"abstract":"<jats:p>The Mediterranean diet (MD) has beneficial effects on human health, which is evidenced by the observation of lower incidence rates of chronic diseases in Mediterranean countries. The MD dietary pattern is rich in antioxidants, such as melatonin, which is a hormone produced mainly by the pineal gland and controls several circadian rhythms. Additionally, melatonin is found in foods, such as fruit and vegetables. The purpose of this systematic review was to assess the melatonin content in Mediterranean foods and to evaluate the influence of the MD on melatonin levels in both humans and model organisms. A comprehensive search was conducted in four databases (PubMed, Scopus, Cochrane Library and Web of Science) and data were extracted. A total of 31 records were chosen. MD-related foods, such as tomatoes, olive oil, red wine, beer, nuts, and vegetables, showed high melatonin contents. The consumption of specific MD foods increases melatonin levels and improves the antioxidant status in plasma.<\/jats:p>","DOI":"10.3390\/antiox12020264","type":"journal-article","created":{"date-parts":[[2023,1,25]],"date-time":"2023-01-25T03:53:18Z","timestamp":1674618798000},"page":"264","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Mediterranean Diet and Melatonin: A Systematic Review"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4003-4400","authenticated-orcid":false,"given":"Elena","family":"Grao-Cruces","sequence":"first","affiliation":[{"name":"Department of Medical Biochemistry, Molecular Biology, and Immunology, School of Medicine, University of Seville, Avenida Sanchez Pizjuan s\/n, 41009 Seville, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Ramon","family":"Calvo","sequence":"additional","affiliation":[{"name":"Department of Medical Biochemistry, Molecular Biology, and Immunology, School of Medicine, University of Seville, Avenida Sanchez Pizjuan s\/n, 41009 Seville, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Dolores","family":"Maldonado-Aibar","sequence":"additional","affiliation":[{"name":"Department of Medical Biochemistry, Molecular Biology, and Immunology, School of Medicine, University of Seville, Avenida Sanchez Pizjuan s\/n, 41009 Seville, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria del Carmen","family":"Millan-Linares","sequence":"additional","affiliation":[{"name":"Department of Medical Biochemistry, Molecular Biology, and Immunology, School of Medicine, University of Seville, Avenida Sanchez Pizjuan s\/n, 41009 Seville, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5400-3192","authenticated-orcid":false,"given":"Sergio","family":"Montserrat-de la Paz","sequence":"additional","affiliation":[{"name":"Department of Medical Biochemistry, Molecular Biology, and Immunology, School of Medicine, University of Seville, Avenida Sanchez Pizjuan s\/n, 41009 Seville, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,1,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1007\/s10654-018-0427-3","article-title":"Evaluating Mediterranean diet and risk of chronic disease in cohort studies: An umbrella review of meta-analysis","volume":"33","author":"Galbete","year":"2018","journal-title":"Eur. 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