{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T20:20:38Z","timestamp":1792182038203,"version":"4.4.0"},"reference-count":90,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2023,2,27]],"date-time":"2023-02-27T00:00:00Z","timestamp":1677456000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antioxidants"],"abstract":"<jats:p>Taking into account the increasing number of antibiotic-resistant bacteria, actual research focused on plant extracts is vital. The aim of our study was to investigate leaf and stem ethanolic extracts of Artemisia absinthium L. and Artemisia annua L. in order to explore their antioxidant and antibacterial activities. Total phenolic content (TPC) was evaluated spectrophotometrically. Antioxidant activity was evaluated by DPPH and ABTS. The antibacterial activity of wormwood extracts was assessed by minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) in Escherichia coli, Staphylococcus aureus, Listeria monocytogenes, and Salmonella enteritidis cultures, and by zone of inhibition in Klebsiella carbapenem-resistant enterobacteriaceae (CRE) and Escherichia coli extended-spectrum \u03b2-lactamases cultures (ESBL). The Artemisia annua L. leaf extract (AnL) exhibited the highest TPC (518.09 mg\/mL) and the highest expression of sinapic acid (285.69 \u00b1 0.002 \u00b5g\/mL). Nevertheless, the highest antioxidant capacity (1360.51 \u00b1 0.04 \u00b5M Trolox\/g DW by ABTS and 735.77 \u00b1 0.02 \u00b5M Trolox\/g DW by DPPH) was found in Artemisia absinthium L. leaf from the second year of vegetation (AbL2). AnL extract exhibited the lowest MIC and MBC for all tested bacteria and the maximal zone of inhibition for Klebsiella CRE and Escherichia\u00a0coli ESBL. Our study revealed that AbL2 exhibited the best antioxidant potential, while AnL extract had the strongest antibacterial effect.<\/jats:p>","DOI":"10.3390\/antiox12030596","type":"journal-article","created":{"date-parts":[[2023,2,28]],"date-time":"2023-02-28T03:00:38Z","timestamp":1677553238000},"page":"596","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":59,"title":["Antibacterial and Phytochemical Screening of Artemisia Species"],"prefix":"10.3390","volume":"12","author":[{"given":"Maria-Evelina","family":"Bordean","sequence":"first","affiliation":[{"name":"Faculty of Food Science and Technology, University of Agricultural Sciences and Veterinary Medicine, 64 Calea Floresti, 400509 Cluj-Napoca, Romania"},{"name":"Centre for Technology Transfer-BioTech, 64 Calea Flore\u0219ti, 400509 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodica Ana","family":"Ungur","sequence":"additional","affiliation":[{"name":"Department of Medical Specialties, Faculty of Medicine, \u201cIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, 8 Victor Babe\u0219 Street, 400012 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3930-5920","authenticated-orcid":false,"given":"Dan Alexandru","family":"Toc","sequence":"additional","affiliation":[{"name":"Department of Microbiology, \u201cIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6337-8831","authenticated-orcid":false,"given":"Ileana Monica","family":"Borda","sequence":"additional","affiliation":[{"name":"Department of Medical Specialties, Faculty of Medicine, \u201cIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, 8 Victor Babe\u0219 Street, 400012 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5543-2001","authenticated-orcid":false,"given":"Georgiana Smaranda","family":"Mar\u021bi\u0219","sequence":"additional","affiliation":[{"name":"Faculty of Food Science and Technology, University of Agricultural Sciences and Veterinary Medicine, 64 Calea Floresti, 400509 Cluj-Napoca, Romania"},{"name":"Centre for Technology Transfer-BioTech, 64 Calea Flore\u0219ti, 400509 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7798-3397","authenticated-orcid":false,"given":"Carmen Rodica","family":"Pop","sequence":"additional","affiliation":[{"name":"Faculty of Food Science and Technology, University of Agricultural Sciences and Veterinary Medicine, 64 Calea Floresti, 400509 Cluj-Napoca, Romania"},{"name":"Centre for Technology Transfer-BioTech, 64 Calea Flore\u0219ti, 400509 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6536-7696","authenticated-orcid":false,"given":"Miu\u021ba","family":"Filip","sequence":"additional","affiliation":[{"name":"Raluca Ripan Institute for Research in Chemistry, Babe\u0219-Bolyai University, 30 F\u00e2nt\u00e2nele Street, 400294 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mihaela","family":"Vlassa","sequence":"additional","affiliation":[{"name":"Raluca Ripan Institute for Research in Chemistry, Babe\u0219-Bolyai University, 30 F\u00e2nt\u00e2nele Street, 400294 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5682-0225","authenticated-orcid":false,"given":"Bogdana Adriana","family":"Nasui","sequence":"additional","affiliation":[{"name":"Department of Community Health, \u201cIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, 6 Louis Pasteur Street, 400349 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3582-1258","authenticated-orcid":false,"given":"Anamaria","family":"Pop","sequence":"additional","affiliation":[{"name":"Faculty of Food Science and Technology, University of Agricultural Sciences and Veterinary Medicine, 64 Calea Floresti, 400509 Cluj-Napoca, Romania"},{"name":"Centre for Technology Transfer-BioTech, 64 Calea Flore\u0219ti, 400509 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delia","family":"Cintez\u0103","sequence":"additional","affiliation":[{"name":"9th Department-Physical Medicine and Rehabilitation, Carol Davila Univerity of Medicine and Pharmacy, 050474 Bucure\u0219ti, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florina Ligia","family":"Popa","sequence":"additional","affiliation":[{"name":"Physical Medicine and Rehabilitation Department, Faculty of Medicine, \u201cLucian 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