{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:54:27Z","timestamp":1792803267876,"version":"4.5.0"},"reference-count":353,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2024,3,10]],"date-time":"2024-03-10T00:00:00Z","timestamp":1710028800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Ministry of Science, Technological Development and Innovation of the Republic of Serbia","award":["451-03-47\/2023-01\/200125"],"award-info":[{"award-number":["451-03-47\/2023-01\/200125"]}],"id":[{"id":"https:\/\/ror.org\/01znas443","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Ministry of Science, Technological Development and Innovation of the Republic of Serbia","award":["506809"],"award-info":[{"award-number":["506809"]}],"id":[{"id":"https:\/\/ror.org\/01znas443","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Ministry of Science, Technological Development and Innovation of the Republic of Serbia","award":["100"],"award-info":[{"award-number":["100"]}],"id":[{"id":"https:\/\/ror.org\/01znas443","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Ministry of Science, Technological Development and Innovation of the Republic of Serbia","award":["156782"],"award-info":[{"award-number":["156782"]}],"id":[{"id":"https:\/\/ror.org\/01znas443","id-type":"ROR","asserted-by":"crossref"}]},{"name":"UCL discretionary fund","award":["451-03-47\/2023-01\/200125"],"award-info":[{"award-number":["451-03-47\/2023-01\/200125"]}]},{"name":"UCL discretionary fund","award":["506809"],"award-info":[{"award-number":["506809"]}]},{"name":"UCL discretionary fund","award":["100"],"award-info":[{"award-number":["100"]}]},{"name":"UCL discretionary fund","award":["156782"],"award-info":[{"award-number":["156782"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antioxidants"],"abstract":"<jats:p>Ferroptosis is a recently discovered type of programmed cell death that is mechanistically different from other types of programmed cell death such as apoptosis, necroptosis, and autophagy. It is characterized by the accumulation of intracellular iron, overproduction of reactive oxygen species, depletion of glutathione, and extensive lipid peroxidation of lipids in the cell membrane. It was discovered that ferroptosis is interconnected with many diseases, such as neurodegenerative diseases, ischemia\/reperfusion injury, cancer, and chronic kidney disease. Polyphenols, plant secondary metabolites known for many bioactivities, are being extensively researched in the context of their influence on ferroptosis which resulted in a great number of publications showing the need for a systematic review. In this review, an extensive literature search was performed. Databases (Scopus, Web of Science, PubMed, ScienceDirect, Springer) were searched in the time span from 2017 to November 2023, using the keyword \u201cferroptosis\u201d alone and in combination with \u201cflavonoid\u201d, \u201cphenolic acid\u201d, \u201cstilbene\u201d, \u201ccoumarin\u201d, \u201canthraquinone\u201d, and \u201cchalcone\u201d; after the selection of studies, we had 311 papers and 143 phenolic compounds. In total, 53 compounds showed the ability to induce ferroptosis, and 110 compounds were able to inhibit ferroptosis, and out of those compounds, 20 showed both abilities depending on the model system. The most researched compounds are shikonin, curcumin, quercetin, resveratrol, and baicalin. The most common modes of action are in the modulation of the Nrf2\/GPX4 and Nrf2\/HO-1 axis and the modulation of iron metabolism.<\/jats:p>","DOI":"10.3390\/antiox13030334","type":"journal-article","created":{"date-parts":[[2024,3,11]],"date-time":"2024-03-11T06:05:30Z","timestamp":1710137130000},"page":"334","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Beyond Mortality: Exploring the Influence of Plant Phenolics on Modulating Ferroptosis\u2014A Systematic Review"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7839-2815","authenticated-orcid":false,"given":"Nemanja","family":"\u017divanovi\u0107","sequence":"first","affiliation":[{"name":"Department of Chemistry, Biochemistry and Environmental Protection, Faculty of Sciences, University of Novi Sad, Trg Dositeja Obradovica 3, 21000 Novi Sad, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9764-9903","authenticated-orcid":false,"given":"Marija","family":"Lesjak","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Biochemistry and Environmental Protection, Faculty of Sciences, University of Novi Sad, Trg Dositeja Obradovica 3, 21000 Novi Sad, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3837-453X","authenticated-orcid":false,"given":"Nata\u0161a","family":"Simin","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Biochemistry and Environmental Protection, Faculty of Sciences, University of Novi Sad, Trg Dositeja Obradovica 3, 21000 Novi Sad, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Surjit K. S.","family":"Srai","sequence":"additional","affiliation":[{"name":"Research Department of Structural and Molecular Biology, Division of Biosciences, University College London, Darwin Building, Gower Street, London WC1E 6BT, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,3,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Ketelut-Carneiro, N., and Fitzgerald, K.A. (2022). Apoptosis, Pyroptosis, and Necroptosis-Oh My! The Many Ways a Cell Can Die. J. Mol. Biol., 434.","DOI":"10.1016\/j.jmb.2021.167378"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.semcdb.2022.09.005","article-title":"Balance between the Cell Viability and Death in 3D","volume":"144","author":"Debruyne","year":"2023","journal-title":"Semin. Cell Dev. Biol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1038\/s41418-017-0012-4","article-title":"Molecular Mechanisms of Cell Death: Recommendations of the Nomenclature Committee on Cell Death 2018","volume":"25","author":"Galluzzi","year":"2018","journal-title":"Cell Death Differ."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"2401","DOI":"10.1016\/j.cell.2022.06.003","article-title":"Ferroptosis Turns 10: Emerging Mechanisms, Physiological Functions, and Therapeutic Applications","volume":"185","author":"Stockwell","year":"2022","journal-title":"Cell"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/j.cell.2012.03.042","article-title":"Ferroptosis: An Iron-Dependent Form of Non-Apoptotic Cell Death","volume":"149","author":"Dixon","year":"2012","journal-title":"Cell"},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Lesjak, M., Simin, N., and Srai, S.K.S. (2022). Can Polyphenols Inhibit Ferroptosis?. Antioxidants, 11.","DOI":"10.3390\/antiox11010150"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"8880141","DOI":"10.1155\/2021\/8880141","article-title":"The Protective Effect of Cyanidin-3-Glucoside on Myocardial Ischemia-Reperfusion Injury through Ferroptosis","volume":"2021","author":"Shan","year":"2021","journal-title":"Oxidative Med. Cell. Longev."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"4412","DOI":"10.1002\/jcp.30901","article-title":"The Role of Ferroptosis in the Development of Acute and Chronic Kidney Diseases","volume":"237","author":"Zhou","year":"2022","journal-title":"J. Cell Physiol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"154117","DOI":"10.1016\/j.phymed.2022.154117","article-title":"Isoliquiritigenin Alleviates Liver Fibrosis through Caveolin-1-Mediated Hepatic Stellate Cells Ferroptosis in Zebrafish and Mice","volume":"101","author":"Huang","year":"2022","journal-title":"Phytomedicine"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"251","DOI":"10.24976\/Discov.Med.202335176.26","article-title":"Curcumin Induces Ferroptosis in A549 CD133+ Cells through the GSH-GPX4 and FSP1-CoQ10-NAPH Pathways","volume":"35","author":"Zhou","year":"2023","journal-title":"Discov. Med."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.semcancer.2019.12.010","article-title":"Repurposing of Plant Alkaloids for Cancer Therapy: Pharmacology and Toxicology","volume":"68","author":"Efferth","year":"2021","journal-title":"Semin. Cancer Biol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1038\/bjc.1972.33","article-title":"Apoptosis: A Basic Biological Phenomenon with Wide-Ranging Implications in Tissue Kinetics","volume":"26","author":"Kerr","year":"1972","journal-title":"Br. J. Cancer"},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Riley, J.S., and Bock, F.J. (2022). Voices from beyond the Grave: The Impact of Apoptosis on the Microenvironment. Biochim. Biophys. Acta Mol. Cell Res., 1869.","DOI":"10.1016\/j.bbamcr.2022.119341"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"119321","DOI":"10.1016\/j.lfs.2021.119321","article-title":"Effects of Non-Drug Treatment on Liver Cells Apoptosis during Hepatic Ischemia-Reperfusion Injury","volume":"275","author":"Wang","year":"2021","journal-title":"Life Sci."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.yjmcc.2019.09.001","article-title":"Molecular Machinery and Interplay of Apoptosis and Autophagy in Coronary Heart Disease","volume":"136","author":"Dong","year":"2019","journal-title":"J. Mol. Cell. Cardiol."},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Li, D., Pi, W., Sun, Z., Liu, X., and Jiang, J. (2022). Ferroptosis and Its Role in Cardiomyopathy. Biomed. Pharmacother., 153.","DOI":"10.1016\/j.biopha.2022.113279"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"101502","DOI":"10.1016\/j.molmet.2022.101502","article-title":"Role and Mechanism of Ferroptosis in Neurological Diseases","volume":"61","author":"Ou","year":"2022","journal-title":"Mol. Metab."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1038\/cr.2016.95","article-title":"Ferroptosis Is an Autophagic Cell Death Process","volume":"26","author":"Gao","year":"2016","journal-title":"Cell Res."},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Yiannikourides, A., and Latunde-Dada, G.O. (2019). A Short Review of Iron Metabolism and Pathophysiology of Iron Disorders. Medicines, 6.","DOI":"10.3390\/medicines6030085"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"111836","DOI":"10.1016\/j.exger.2022.111836","article-title":"Ferroptosis\u2014A New Target of Osteoporosis","volume":"165","author":"Gao","year":"2022","journal-title":"Exp. Gerontol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/j.jgg.2022.06.002","article-title":"Understanding the Mechanistic Regulation of Ferroptosis in Cancer: The Gene Matters","volume":"49","author":"Gao","year":"2022","journal-title":"J. Genet. Genom."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1038\/s41589-019-0330-6","article-title":"A PCBP1-BolA2 Chaperone Complex Delivers Iron for Cytosolic [2Fe-2S] Cluster Assembly","volume":"15","author":"Patel","year":"2019","journal-title":"Nat. Chem. Biol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1021\/acscentsci.9b01063","article-title":"GTP Cyclohydrolase 1\/Tetrahydrobiopterin Counteract Ferroptosis through Lipid Remodeling","volume":"6","author":"Kraft","year":"2020","journal-title":"ACS Cent. Sci."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"215854","DOI":"10.1016\/j.canlet.2022.215854","article-title":"Induction of Ferroptosis in Head and Neck Cancer: A Novel Bridgehead for Fighting Cancer Resilience","volume":"546","author":"Lee","year":"2022","journal-title":"Cancer Lett."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/j.chembiol.2020.03.011","article-title":"Breakdown of an Ironclad Defense System: The Critical Role of NRF2 in Mediating Ferroptosis","volume":"27","author":"Anandhan","year":"2020","journal-title":"Cell Chem. Biol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.freeradbiomed.2018.05.074","article-title":"The Tumor Suppressor Protein P53 and the Ferroptosis Network","volume":"133","author":"Kang","year":"2019","journal-title":"Free Radic. Biol. Med."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1038\/s41418-022-00943-y","article-title":"P53 in Ferroptosis Regulation: The New Weapon for the Old Guardian","volume":"29","author":"Liu","year":"2022","journal-title":"Cell Death Differ."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"100038","DOI":"10.1016\/j.stress.2021.100038","article-title":"Functional Aspects of Plant Secondary Metabolites in Metal Stress Tolerance and Their Importance in Pharmacology","volume":"2","author":"Anjitha","year":"2021","journal-title":"Plant Stress"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.copbio.2021.11.010","article-title":"Diversity: Current and Prospective Secondary Metabolites for Nutrition and Medicine","volume":"74","author":"Sreenivasulu","year":"2022","journal-title":"Curr. Opin. Biotechnol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1016\/j.jff.2015.06.018","article-title":"Phenolics and Polyphenolics in Foods, Beverages and Spices: Antioxidant Activity and Health Effects\u2014A Review","volume":"18","author":"Shahidi","year":"2015","journal-title":"J. Funct. Foods"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"132531","DOI":"10.1016\/j.foodchem.2022.132531","article-title":"Plant Flavonoids: Classification, Distribution, Biosynthesis, and Antioxidant Activity","volume":"383","author":"Shen","year":"2022","journal-title":"Food Chem."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"174867","DOI":"10.1016\/j.ejphar.2022.174867","article-title":"Coumarins Derivatives and Inflammation: Review of Their Effects on the Inflammatory Signaling Pathways","volume":"922","author":"Rostom","year":"2022","journal-title":"Eur. J. Pharmacol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"113128","DOI":"10.1016\/j.phytochem.2022.113128","article-title":"Stilbenes: Source Plants, Chemistry, Biosynthesis, Pharmacology, Application and Problems Related to Their Clinical Application-A Comprehensive Review","volume":"197","author":"Teka","year":"2022","journal-title":"Phytochemistry"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"121605","DOI":"10.1016\/j.ijpharm.2022.121605","article-title":"The Science of Resveratrol, Formulation, Pharmacokinetic Barriers and Its Chemotherapeutic Potential","volume":"618","author":"Robertson","year":"2022","journal-title":"Int. J. Pharm."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.sajb.2020.08.008","article-title":"Review on Tannins: Extraction Processes, Applications and Possibilities","volume":"135","author":"Das","year":"2020","journal-title":"S. Afr. J. Bot."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 Statement: An Updated Guideline for Reporting Systematic Reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.freeradbiomed.2023.05.008","article-title":"Erianin Inhibits the Growth and Metastasis through Autophagy-Dependent Ferroptosis in KRASG13D Colorectal Cancer","volume":"204","author":"Miao","year":"2023","journal-title":"Free Radic. Biol. Med."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1016\/j.bbrc.2019.06.070","article-title":"Typhaneoside Prevents Acute Myeloid Leukemia (AML) through Suppressing Proliferation and Inducing Ferroptosis Associated with Autophagy","volume":"516","author":"Zhu","year":"2019","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"ref_39","doi-asserted-by":"crossref","unstructured":"Yue, L., Yang, Y.-R., Ma, W.-X., Wang, H.-Y., Fan, Q.-W., Wang, Y.-Y., Li, C., Wang, J., Hu, Z.-M., and Wang, X.-F. (2022). Epigallocatechin Gallate Attenuates Gentamicin-Induced Nephrotoxicity by Suppressing Apoptosis and Ferroptosis. Molecules, 27.","DOI":"10.3390\/molecules27238564"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1002\/cbin.12072","article-title":"Gambogenic Acid Inhibits Proliferation and Ferroptosis by Targeting the miR-1291\/FOXA2 and AMPK\u03b1\/SLC7A11\/GPX4 Axis in Colorectal Cancer","volume":"47","author":"Ma","year":"2023","journal-title":"Cell Biol. Int."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"775506","DOI":"10.3389\/fphar.2021.775506","article-title":"Natural Product Erianin Inhibits Bladder Cancer Cell Growth by Inducing Ferroptosis via NRF2 Inactivation","volume":"12","author":"Xiang","year":"2021","journal-title":"Front. Pharmacol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"9523491","DOI":"10.1155\/2022\/9523491","article-title":"Xanthohumol Protects the Rat Myocardium against Ischemia\/Reperfusion Injury-Induced Ferroptosis","volume":"2022","author":"Lin","year":"2022","journal-title":"Oxidative Med. Cell. Longev."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"7885","DOI":"10.1039\/D2FO00357K","article-title":"Activation of Atg7-Dependent Autophagy by a Novel Inhibitor of the Keap1-Nrf2 Protein-Protein Interaction from Penthorum Chinense Pursh. Attenuates 6-Hydroxydopamine-Induced Ferroptosis in Zebrafish and Dopaminergic Neurons","volume":"13","author":"Sun","year":"2022","journal-title":"Food Funct."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"118660","DOI":"10.1016\/j.lfs.2020.118660","article-title":"Galangin Attenuated Cerebral Ischemia-Reperfusion Injury by Inhibition of Ferroptosis through Activating the SLC7A11\/GPX4 Axis in Gerbils","volume":"264","author":"Guan","year":"2021","journal-title":"Life Sci."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1007\/s12550-023-00504-3","article-title":"Curcumin Alleviates AFB1-Induced Nephrotoxicity in Ducks: Regulating Mitochondrial Oxidative Stress, Ferritinophagy, and Ferroptosis","volume":"39","author":"Liu","year":"2023","journal-title":"Mycotoxin Res."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"629379","DOI":"10.3389\/fphar.2021.629379","article-title":"Baicalin Inhibits Ferroptosis in Intracerebral Hemorrhage","volume":"12","author":"Duan","year":"2021","journal-title":"Front. Pharmacol."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1248\/bpb.b19-00824","article-title":"Gastrodin Inhibits H2O2-Induced Ferroptosis through Its Antioxidative Effect in Rat Glioma Cell Line C6","volume":"43","author":"Jiang","year":"2020","journal-title":"Biol. Pharm. Bull."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"113644","DOI":"10.1016\/j.fct.2023.113644","article-title":"Cardamonin Alleviates Chondrocytes Inflammation and Cartilage Degradation of Osteoarthritis by Inhibiting Ferroptosis via P53 Pathway","volume":"174","author":"Gong","year":"2023","journal-title":"Food Chem. Toxicol."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1248\/bpb.b22-00174","article-title":"Puerarin Protects against Myocardial Ischemia\/Reperfusion Injury by Inhibiting Ferroptosis","volume":"46","author":"Ding","year":"2023","journal-title":"Biol. Pharm. Bull."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"e17874","DOI":"10.1016\/j.heliyon.2023.e17874","article-title":"Curcumin Preconditioning Enhances the Neuroprotective Effects of Olfactory Mucosa-Derived Mesenchymal Stem Cells on Experimental Intracerebral Hemorrhage","volume":"9","author":"Huang","year":"2023","journal-title":"Heliyon"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1111\/1759-7714.13904","article-title":"Curcumin Induces Ferroptosis in Non-Small-Cell Lung Cancer via Activating Autophagy","volume":"12","author":"Tang","year":"2021","journal-title":"Thorac. Cancer"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"2242","DOI":"10.1016\/j.fshw.2023.03.044","article-title":"Apigenin, a Natural Flavonoid, Promotes Autophagy and Ferroptosis in Human Endometrial Carcinoma Ishikawa Cells in Vitro and in Vivo","volume":"12","author":"Liang","year":"2023","journal-title":"Food Sci. Hum. Wellness"},{"key":"ref_53","doi-asserted-by":"crossref","unstructured":"Tsai, K.-Y., Wei, P.-L., Lee, C.-C., Makondi, P.T., Chen, H.-A., Chang, Y.-Y., Liu, D.-Z., Huang, C.-Y., and Chang, Y.-J. (2023). 2,3,5,4\u2032-Tetrahydroxystilbene (TG1), a Novel Compound Derived from 2,3,5,4\u2032-Tetrahydroxystilbene-2-O-\u03b2-D-Glucoside (THSG), Inhibits Colorectal Cancer Progression by Inducing Ferroptosis, Apoptosis, and Autophagy. Biomedicines, 11.","DOI":"10.3390\/biomedicines11071798"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"154881","DOI":"10.1016\/j.phymed.2023.154881","article-title":"Baicalin Induces Ferroptosis in Osteosarcomas through a Novel Nrf2\/xCT\/GPX4 Regulatory Axis","volume":"116","author":"Wen","year":"2023","journal-title":"Phytomedicine"},{"key":"ref_55","doi-asserted-by":"crossref","unstructured":"Yuan, J., Khan, S.U., Yan, J., Lu, J., Yang, C., and Tong, Q. (2023). Baicalin Enhances the Efficacy of 5-Fluorouracil in Gastric Cancer by Promoting ROS-Mediated Ferroptosis. Biomed. Pharmacother., 164.","DOI":"10.1016\/j.biopha.2023.114986"},{"key":"ref_56","doi-asserted-by":"crossref","unstructured":"Miyazaki, K., Xu, C., Shimada, M., and Goel, A. (2023). Curcumin and Andrographis Exhibit Anti-Tumor Effects in Colorectal Cancer via Activation of Ferroptosis and Dual Suppression of Glutathione Peroxidase-4 and Ferroptosis Suppressor Protein-1. Pharmaceuticals, 16.","DOI":"10.3390\/ph16030383"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"367","DOI":"10.7150\/jca.81027","article-title":"Erianin Induces Ferroptosis of Renal Cancer Stem Cells via Promoting ALOX12\/P53 mRNA N6-Methyladenosine Modification","volume":"14","author":"Shen","year":"2023","journal-title":"J. Cancer"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"6896790","DOI":"10.1155\/2023\/6896790","article-title":"Curcumin Induces Ferroptosis in Follicular Thyroid Cancer by Upregulating HO-1 Expression","volume":"2023","author":"Chen","year":"2023","journal-title":"Oxidative Med. Cell. Longev."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1080\/01635581.2022.2139398","article-title":"Curcumin Represses Colorectal Cancer Cell Proliferation by Triggering Ferroptosis via PI3K\/Akt\/mTOR Signaling","volume":"75","author":"Chen","year":"2023","journal-title":"Nutr. Cancer"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"3158","DOI":"10.21037\/tcr-21-227","article-title":"Curcumin Reverses the Sunitinib Resistance in Clear Cell Renal Cell Carcinoma (ccRCC) through the Induction of Ferroptosis via the ADAMTS18 Gene","volume":"10","author":"Xu","year":"2021","journal-title":"Transl. Cancer Res."},{"key":"ref_61","doi-asserted-by":"crossref","unstructured":"Cao, X., Li, Y., Wang, Y., Yu, T., Zhu, C., Zhang, X., and Guan, J. (2022). Curcumin Suppresses Tumorigenesis by Ferroptosis in Breast Cancer. PLoS ONE, 17.","DOI":"10.1371\/journal.pone.0261370"},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1111\/cbdd.14288","article-title":"Amentoflavone Attenuates Cell Proliferation and Induces Ferroptosis in Human Gastric Cancer by miR-496\/ATF2 Axis","volume":"102","author":"Tang","year":"2023","journal-title":"Chem. Biol. Drug Des."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"13269","DOI":"10.1080\/21655979.2022.2079256","article-title":"Amentoflavone Promotes Ferroptosis by Regulating Reactive Oxygen Species (ROS)\/5\u2032AMP-Activated Protein Kinase (AMPK)\/Mammalian Target of Rapamycin (mTOR) to Inhibit the Malignant Progression of Endometrial Carcinoma Cells","volume":"13","author":"Sun","year":"2022","journal-title":"Bioengineered"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"117425","DOI":"10.1016\/j.lfs.2020.117425","article-title":"Amentoflavone Suppresses Cell Proliferation and Induces Cell Death through Triggering Autophagy-Dependent Ferroptosis in Human Glioma","volume":"247","author":"Chen","year":"2020","journal-title":"Life Sci."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"4045","DOI":"10.1016\/j.apsb.2021.03.036","article-title":"Baicalin Induces Ferroptosis in Bladder Cancer Cells by Downregulating FTH1","volume":"11","author":"Kong","year":"2021","journal-title":"Acta Pharm. Sin. B"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1002\/tox.23832","article-title":"Erianin Suppressed Lung Cancer Stemness and Chemotherapeutic Sensitivity via Triggering Ferroptosis","volume":"39","author":"Lv","year":"2023","journal-title":"Environ. Toxicol."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1038\/s41392-020-0149-3","article-title":"Erianin, a Novel Dibenzyl Compound in Dendrobium Extract, Inhibits Lung Cancer Cell Growth and Migration via Calcium\/Calmodulin-Dependent Ferroptosis","volume":"5","author":"Chen","year":"2020","journal-title":"Signal Transduct. Target. Ther."},{"key":"ref_68","doi-asserted-by":"crossref","unstructured":"Wang, M., Cheng, H., Wu, H., Liu, C., Li, S., Li, B., Su, J., Luo, S., and Li, Q. (2022). Gambogenic Acid Antagonizes the Expression and Effects of Long Non-Coding RNA NEAT1 and Triggers Autophagy and Ferroptosis in Melanoma. Biomed. Pharmacother., 154.","DOI":"10.1016\/j.biopha.2022.113636"},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.bbrc.2021.11.101","article-title":"Auriculasin Enhances ROS Generation to Regulate Colorectal Cancer Cell Apoptosis, Ferroptosis, Oxeiptosis, Invasion and Colony Formation","volume":"587","author":"Wang","year":"2022","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"1129662","DOI":"10.3389\/fphar.2023.1129662","article-title":"Wogonin Induces Ferroptosis in Pancreatic Cancer Cells by Inhibiting the Nrf2\/GPX4 Axis","volume":"14","author":"Liu","year":"2023","journal-title":"Front. Pharmacol."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1111\/bph.15350","article-title":"Quercetin Induces P53-Independent Cancer Cell Death through Lysosome Activation by the Transcription Factor EB and Reactive Oxygen Species-Dependent Ferroptosis","volume":"178","author":"Wang","year":"2021","journal-title":"Br. J. Pharmacol."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"5299218","DOI":"10.1155\/2022\/5299218","article-title":"Quercetin Promotes TFEB Nuclear Translocation and Activates Lysosomal Degradation of Ferritin to Induce Ferroptosis in Breast Cancer Cells","volume":"2022","author":"An","year":"2022","journal-title":"Comput. Intell. Neurosci."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"154701","DOI":"10.1016\/j.phymed.2023.154701","article-title":"Shikonin and Cisplatin Synergistically Overcome Cisplatin Resistance of Ovarian Cancer by Inducing Ferroptosis via Upregulation of HMOX1 to Promote Fe2+ Accumulation","volume":"112","author":"Ni","year":"2023","journal-title":"Phytomedicine"},{"key":"ref_74","doi-asserted-by":"crossref","unstructured":"Qian, X., Zhu, L., Xu, M., Liu, H., Yu, X., Shao, Q., and Qin, J. (2023). Shikonin Suppresses Small Cell Lung Cancer Growth via Inducing ATF3-Mediated Ferroptosis to Promote ROS Accumulation. Chem. Biol. Interact., 382.","DOI":"10.1016\/j.cbi.2023.110588"},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"105627","DOI":"10.1016\/j.tiv.2023.105627","article-title":"Scoparone Induces Both Apoptosis and Ferroptosis via Multiple Mechanisms in Non-Small-Cell Lung Cancer Cells","volume":"91","author":"Shen","year":"2023","journal-title":"Toxicol In Vitro"},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/s00280-023-04549-0","article-title":"Osthole Inhibits Malignant Phenotypes and Induces Ferroptosis in KRAS-Mutant Colorectal Cancer Cells via Suppressing AMPK\/Akt Signaling","volume":"92","author":"Zhou","year":"2023","journal-title":"Cancer Chemother. Pharmacol."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"873090","DOI":"10.3389\/fphar.2022.873090","article-title":"Naringin Relieves Diabetic Cardiac Autonomic Neuropathy Mediated by P2Y14 Receptor in Superior Cervical Ganglion","volume":"13","author":"Tang","year":"2022","journal-title":"Front. Pharmacol."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1142\/S0192415X23500465","article-title":"Quercetin Ameliorates Diabetic Kidney Injury by Inhibiting Ferroptosis via Activating Nrf2\/HO-1 Signaling Pathway","volume":"51","author":"Feng","year":"2023","journal-title":"Am. J. Chin. Med."},{"key":"ref_79","doi-asserted-by":"crossref","unstructured":"Li, Y., Huang, Z., Pan, S., Feng, Y., He, H., Cheng, S., Wang, L., Wang, L., and Pathak, J.L. (2023). Resveratrol Alleviates Diabetic Periodontitis-Induced Alveolar Osteocyte Ferroptosis Possibly via Regulation of SLC7A11\/GPX4. Nutrients, 15.","DOI":"10.3390\/nu15092115"},{"key":"ref_80","doi-asserted-by":"crossref","unstructured":"Xiong, D., Hu, W., Han, X., and Cai, Y. (2023). Rhein Inhibited Ferroptosis and EMT to Attenuate Diabetic Nephropathy by Regulating the Rac1\/NOX1\/\u03b2-Catenin Axis. Front. Biosci., 28.","DOI":"10.31083\/j.fbl2805100"},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1186\/s10020-022-00481-w","article-title":"Glabridin, a Bioactive Component of Licorice, Ameliorates Diabetic Nephropathy by Regulating Ferroptosis and the VEGF\/Akt\/ERK Pathways","volume":"28","author":"Tan","year":"2022","journal-title":"Mol. Med."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"3159717","DOI":"10.1155\/2022\/3159717","article-title":"Curcumin Attenuates Ferroptosis-Induced Myocardial Injury in Diabetic Cardiomyopathy through the Nrf2 Pathway","volume":"2022","author":"Wei","year":"2022","journal-title":"Cardiovasc. Ther."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"137404","DOI":"10.1016\/j.neulet.2023.137404","article-title":"Dihydromyricetin Alleviates Hippocampal Ferroptosis in Type 2 Diabetic Cognitive Impairment Rats via Inhibiting the JNK-Inflammatory Factor Pathway","volume":"812","author":"Wang","year":"2023","journal-title":"Neurosci. Lett."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"175642","DOI":"10.1016\/j.ejphar.2023.175642","article-title":"Ferulic Acid Alleviates High Fat Diet-Induced Cognitive Impairment by Inhibiting Oxidative Stress and Apoptosis","volume":"946","author":"Mei","year":"2023","journal-title":"Eur. J. Pharmacol."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"1730","DOI":"10.1016\/j.fshw.2023.02.035","article-title":"Isoforsythiaside Confers Neuroprotection against Alzheimer\u2019s Disease by Attenuating Ferroptosis and Neuroinflammation in Vivo and in Vitro","volume":"12","author":"Wang","year":"2023","journal-title":"Food Sci. Hum. Wellness"},{"key":"ref_86","doi-asserted-by":"crossref","unstructured":"Luo, J., Lu, Q., Sun, B., Shao, N., Huang, W., Hu, G., Cai, B., and Si, W. (2023). Chrysophanol Improves Memory Impairment and Cell Injury by Reducing the Level of Ferroptosis in A\u03b225\u201335 Treated Rat and PC12 Cells. 3 Biotech, 13.","DOI":"10.1007\/s13205-023-03769-8"},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"110290","DOI":"10.1016\/j.intimp.2023.110290","article-title":"Sennoside A Restrains TRAF6 Level to Modulate Ferroptosis, Inflammation and Cognitive Impairment in Aging Mice with Alzheimer\u2019s Disease","volume":"120","author":"Li","year":"2023","journal-title":"Int. Immunopharmacol."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"14756","DOI":"10.1002\/jcb.28736","article-title":"Eriodictyol Alleviates Lipopolysaccharide-Triggered Oxidative Stress and Synaptic Dysfunctions in BV-2 Microglial Cells and Mouse Brain","volume":"120","author":"He","year":"2019","journal-title":"J. Cell. Biochem."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s10020-022-00442-3","article-title":"Eriodictyol Ameliorates Cognitive Dysfunction in APP\/PS1 Mice by Inhibiting Ferroptosis via Vitamin D Receptor-Mediated Nrf2 Activation","volume":"28","author":"Li","year":"2022","journal-title":"Mol. Med."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1080\/13880209.2022.2123941","article-title":"Echinatin Mitigates Sevoflurane-Induced Hippocampal Neurotoxicity and Cognitive Deficits through Mitigation of Iron Overload and Oxidative Stress","volume":"60","author":"Xu","year":"2022","journal-title":"Pharm. Biol."},{"key":"ref_91","doi-asserted-by":"crossref","unstructured":"Li, Y., Zhang, E., Yang, H., Chen, Y., Tao, L., Xu, Y., Chen, T., and Shen, X. (2022). Gastrodin Ameliorates Cognitive Dysfunction in Vascular Dementia Rats by Suppressing Ferroptosis via the Regulation of the Nrf2\/Keap1-GPx4 Signaling Pathway. Molecules, 27.","DOI":"10.3390\/molecules27196311"},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"104715","DOI":"10.1016\/j.tiv.2019.104715","article-title":"Gastrodin Protects against Glutamate-Induced Ferroptosis in HT-22 Cells through Nrf2\/HO-1 Signaling Pathway","volume":"62","author":"Jiang","year":"2020","journal-title":"Toxicol In Vitro"},{"key":"ref_93","first-page":"11546","article-title":"Icariin Improves Cognitive Impairment by Inhibiting Ferroptosis of Nerve Cells","volume":"15","author":"Yang","year":"2023","journal-title":"Aging"},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.freeradbiomed.2022.09.001","article-title":"Quercetin Alleviates Kainic Acid-Induced Seizure by Inhibiting the Nrf2-Mediated Ferroptosis Pathway","volume":"191","author":"Xie","year":"2022","journal-title":"Free Radic. Biol. Med."},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"7769355","DOI":"10.1155\/2022\/7769355","article-title":"Quercetin Protects against MPP+\/MPTP-Induced Dopaminergic Neuron Death in Parkinson\u2019s Disease by Inhibiting Ferroptosis","volume":"2022","author":"Lin","year":"2022","journal-title":"Oxidative Med. Cell. Longev."},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"154762","DOI":"10.1016\/j.phymed.2023.154762","article-title":"Salidroside Alleviates Cognitive Impairment by Inhibiting Ferroptosis via Activation of the Nrf2\/GPX4 Axis in SAMP8 Mice","volume":"114","author":"Yang","year":"2023","journal-title":"Phytomedicine"},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1186\/s13020-022-00634-3","article-title":"Salidroside Attenuates Neuronal Ferroptosis by Activating the Nrf2\/HO1 Signaling Pathway in A\u03b21-42-Induced Alzheimer\u2019s Disease Mice and Glutamate-Injured HT22 Cells","volume":"17","author":"Yang","year":"2022","journal-title":"Chin. Med."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"108002","DOI":"10.1016\/j.intimp.2021.108002","article-title":"Tetrahydroxy Stilbene Glycoside Ameliorates Alzheimer\u2019s Disease in APP\/PS1 Mice via Glutathione Peroxidase Related Ferroptosis","volume":"99","author":"Gao","year":"2021","journal-title":"Int. Immunopharmacol."},{"key":"ref_99","doi-asserted-by":"crossref","unstructured":"Liu, P., Chen, W., Kang, Y., Wang, C., Wang, X., Liu, W., Hayashi, T., Qiu, Z., Mizuno, K., and Hattori, S. (2023). Silibinin Ameliorates STING-Mediated Neuroinflammation via Downregulation of Ferroptotic Damage in a Sporadic Alzheimer\u2019s Disease Model. Arch. Biochem. Biophys., 744.","DOI":"10.1016\/j.abb.2023.109691"},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.bbrc.2021.03.108","article-title":"Polydatin Alleviates Traumatic Brain Injury: Role of Inhibiting Ferroptosis","volume":"556","author":"Huang","year":"2021","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"ref_101","doi-asserted-by":"crossref","unstructured":"Huang, Y., Wu, H., Hu, Y., Zhou, C., Wu, J., Wu, Y., Wang, H., Lenahan, C., Huang, L., and Nie, S. (2022). Puerarin Attenuates Oxidative Stress and Ferroptosis via AMPK\/PGC1\u03b1\/Nrf2 Pathway after Subarachnoid Hemorrhage in Rats. Antioxidants, 11.","DOI":"10.3390\/antiox11071259"},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"114568","DOI":"10.1016\/j.expneurol.2023.114568","article-title":"Anacardic Acid Improves Neurological Deficits in Traumatic Brain Injury by Anti-Ferroptosis and Anti-Inflammation","volume":"370","author":"Liu","year":"2023","journal-title":"Exp. Neurol."},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"638","DOI":"10.3389\/fphar.2019.00638","article-title":"Baicalein Exerts Neuroprotective Effects in FeCl3-Induced Posttraumatic Epileptic Seizures via Suppressing Ferroptosis","volume":"10","author":"Li","year":"2019","journal-title":"Front. Pharmacol."},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"7794","DOI":"10.1080\/21655979.2021.1975999","article-title":"Baicalin Suppresses Autophagy-Dependent Ferroptosis in Early Brain Injury after Subarachnoid Hemorrhage","volume":"12","author":"Zheng","year":"2021","journal-title":"Bioengineered"},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"52","DOI":"10.5500\/wjt.v5.i2.52","article-title":"Update on Ischemia-Reperfusion Injury in Kidney Transplantation: Pathogenesis and Treatment","volume":"5","author":"Salvadori","year":"2015","journal-title":"World J. Transplant."},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.gene.2018.05.009","article-title":"Isorhamnetin Protects against Hypoxia\/Reoxygenation-Induced Injure by Attenuating Apoptosis and Oxidative Stress in H9c2 Cardiomyocytes","volume":"666","author":"Zhao","year":"2018","journal-title":"Gene"},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.freeradbiomed.2022.03.033","article-title":"Old Targets, New Strategy: Apigenin-7-O-\u03b2-d-(-6\u2033-p-Coumaroyl)-Glucopyranoside Prevents Endothelial Ferroptosis and Alleviates Intestinal Ischemia-Reperfusion Injury through HO-1 and MAO-B Inhibition","volume":"184","author":"Feng","year":"2022","journal-title":"Free Radic. Biol. Med."},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"2495","DOI":"10.2147\/DDDT.S409232","article-title":"Galangin Attenuates Myocardial Ischemic Reperfusion-Induced Ferroptosis by Targeting Nrf2\/Gpx4 Signaling Pathway","volume":"17","author":"Yang","year":"2023","journal-title":"Drug Des. Dev. Ther."},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"e22569","DOI":"10.1096\/fj.202200935R","article-title":"Galangin Inhibited Ferroptosis through Activation of the PI3K\/AKT Pathway in Vitro and in Vivo","volume":"36","author":"Chen","year":"2022","journal-title":"FASEB J."},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1093\/bbb\/zbac048","article-title":"Resveratrol Pretreatment Protects Neurons from Oxygen-Glucose Deprivation\/Reoxygenation and Ischemic Injury through Inhibiting Ferroptosis","volume":"86","author":"Zhu","year":"2022","journal-title":"Biosci. Biotechnol. Biochem."},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"145968","DOI":"10.1016\/j.gene.2021.145968","article-title":"Resveratrol Protects against Myocardial Ischemia-Reperfusion Injury via Attenuating Ferroptosis","volume":"808","author":"Li","year":"2022","journal-title":"Gene"},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1186\/s10020-023-00730-6","article-title":"Resveratrol Reduces ROS-Induced Ferroptosis by Activating SIRT3 and Compensating the GSH\/GPX4 Pathway","volume":"29","author":"Wang","year":"2023","journal-title":"Mol. Med."},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"114541","DOI":"10.1016\/j.expneurol.2023.114541","article-title":"Rhein Attenuates Cerebral Ischemia-Reperfusion Injury via Inhibition of Ferroptosis through NRF2\/SLC7A11\/GPX4 Pathway","volume":"369","author":"Liu","year":"2023","journal-title":"Exp. Neurol."},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1007\/s11064-022-03829-0","article-title":"Vitexin Improves Cerebral Ischemia-reperfusion Injury by Attenuating Oxidative Injury and Ferroptosis via Keap1\/Nrf2\/HO-1signaling","volume":"48","author":"Guo","year":"2023","journal-title":"Neurochem. Res."},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"10924","DOI":"10.1080\/21655979.2021.1995994","article-title":"Naringenin Alleviates Myocardial Ischemia\/Reperfusion Injury by Regulating the Nuclear Factor-Erythroid Factor 2-Related Factor 2 (Nrf2)\/System Xc-\/Glutathione Peroxidase 4 (GPX4) Axis to Inhibit Ferroptosis","volume":"12","author":"Xu","year":"2021","journal-title":"Bioengineered"},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"154729","DOI":"10.1016\/j.phymed.2023.154729","article-title":"Loureirin C Inhibits Ferroptosis after Cerebral Ischemia Reperfusion through Regulation of the Nrf2 Pathway in Mice","volume":"113","author":"Liu","year":"2023","journal-title":"Phytomedicine"},{"key":"ref_117","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1038\/s41401-023-01177-5","article-title":"Caffeic Acid Alleviates Cerebral Ischemic Injury in Rats by Resisting Ferroptosis via Nrf2 Signaling Pathway","volume":"45","author":"Li","year":"2023","journal-title":"Acta Pharmacol. Sin."},{"key":"ref_118","doi-asserted-by":"crossref","unstructured":"Li, M., Meng, Z., Yu, S., Li, J., Wang, Y., Yang, W., and Wu, H. (2022). Baicalein Ameliorates Cerebral Ischemia-Reperfusion Injury by Inhibiting Ferroptosis via Regulating GPX4\/ACSL4\/ACSL3 Axis. Chem. Biol. Interact., 366.","DOI":"10.1016\/j.cbi.2022.110137"},{"key":"ref_119","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.ijcard.2022.12.018","article-title":"Baicalein and Luteolin Inhibit Ischemia\/Reperfusion-Induced Ferroptosis in Rat Cardiomyocytes","volume":"375","author":"Wang","year":"2023","journal-title":"Int. J. Cardiol."},{"key":"ref_120","doi-asserted-by":"crossref","unstructured":"Yuan, Y., Zhai, Y., Chen, J., Xu, X., and Wang, H. (2021). Kaempferol Ameliorates Oxygen-Glucose Deprivation\/Reoxygenation-Induced Neuronal Ferroptosis by Activating Nrf2\/SLC7A11\/GPX4 Axis. Biomolecules, 11.","DOI":"10.3390\/biom11070923"},{"key":"ref_121","doi-asserted-by":"crossref","unstructured":"Dai, C., Li, H., Wang, Y., Tang, S., Velkov, T., and Shen, J. (2021). Inhibition of Oxidative Stress and ALOX12 and NF-\u03baB Pathways Contribute to the Protective Effect of Baicalein on Carbon Tetrachloride-Induced Acute Liver Injury. Antioxidants, 10.","DOI":"10.3390\/antiox10060976"},{"key":"ref_122","doi-asserted-by":"crossref","first-page":"7692","DOI":"10.1039\/D3FO01684F","article-title":"Nobiletin Protects against Ferroptosis to Alleviate Sepsis-Associated Acute Liver Injury by Modulating the Gut Microbiota","volume":"14","author":"Huang","year":"2023","journal-title":"Food Funct."},{"key":"ref_123","doi-asserted-by":"crossref","first-page":"7427","DOI":"10.1021\/acs.jafc.3c01378","article-title":"Quercetin Alleviates Acrylamide-Induced Liver Injury by Inhibiting Autophagy-Dependent Ferroptosis","volume":"71","author":"Huang","year":"2023","journal-title":"J. Agric. Food Chem."},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"115331","DOI":"10.1016\/j.ecoenv.2023.115331","article-title":"Salidroside Ameliorates Acetaminophen-Induced Acute Liver Injury through the Inhibition of Endoplasmic Reticulum Stress-Mediated Ferroptosis by Activating the AMPK\/SIRT1 Pathway","volume":"262","author":"Xu","year":"2023","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"ref_125","doi-asserted-by":"crossref","first-page":"1884","DOI":"10.1039\/D2FO02716J","article-title":"Kaempferol Prevents Acetaminophen-Induced Liver Injury by Suppressing Hepatocyte Ferroptosis via Nrf2 Pathway Activation","volume":"14","author":"Li","year":"2023","journal-title":"Food Funct."},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"1148814","DOI":"10.3389\/fphar.2023.1148814","article-title":"Epigallocatechin Gallate Alleviates High-Fat Diet-Induced Hepatic Lipotoxicity by Targeting Mitochondrial ROS-Mediated Ferroptosis","volume":"14","author":"Ding","year":"2023","journal-title":"Front. Pharmacol."},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"4230","DOI":"10.1002\/ptr.7558","article-title":"Wogonoside Attenuates Liver Fibrosis by Triggering Hepatic Stellate Cell Ferroptosis through SOCS1\/P53\/SLC7A11 Pathway","volume":"36","author":"Liu","year":"2022","journal-title":"Phytother. Res."},{"key":"ref_128","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.jphs.2020.07.014","article-title":"Chrysophanol Attenuates Hepatitis B Virus X Protein-Induced Hepatic Stellate Cell Fibrosis by Regulating Endoplasmic Reticulum Stress and Ferroptosis","volume":"144","author":"Kuo","year":"2020","journal-title":"J. Pharmacol. Sci."},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1002\/fsn3.3065","article-title":"Danshensu Attenuated Lipopolysaccharide-Induced LX-2 and T6 Cells Activation through Regulation of Ferroptosis","volume":"11","author":"Wang","year":"2023","journal-title":"Food Sci. Nutr."},{"key":"ref_130","doi-asserted-by":"crossref","first-page":"118","DOI":"10.3892\/ijmm.2023.5321","article-title":"Quercetin Alleviates Lipopolysaccharide-induced Acute Lung Injury by Inhibiting Ferroptosis via the Sirt1\/Nrf2\/Gpx4 Pathway","volume":"52","author":"Deng","year":"2023","journal-title":"Int. J. Mol. Med."},{"key":"ref_131","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1186\/s12964-022-00994-1","article-title":"Salidroside Attenuates HALI via IL-17A-Mediated Ferroptosis of Alveolar Epithelial Cells by Regulating Act1-TRAF6-P38 MAPK Pathway","volume":"20","author":"Guo","year":"2022","journal-title":"Cell Commun. Signal."},{"key":"ref_132","doi-asserted-by":"crossref","first-page":"706327","DOI":"10.3389\/fped.2021.706327","article-title":"Puerarin Inhibits Ferroptosis and Inflammation of Lung Injury Caused by Sepsis in LPS Induced Lung Epithelial Cells","volume":"9","author":"Xu","year":"2021","journal-title":"Front. Pediatr."},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.intimp.2018.10.042","article-title":"Chicoric Acid Alleviates Lipopolysaccharide-Induced Acute Lung Injury in Mice through Anti-Inflammatory and Anti-Oxidant Activities","volume":"66","author":"Ding","year":"2019","journal-title":"Int. Immunopharmacol."},{"key":"ref_134","doi-asserted-by":"crossref","first-page":"2286","DOI":"10.1080\/13880209.2022.2147549","article-title":"Ferulic Acid Alleviates Alveolar Epithelial Barrier Dysfunction in Sepsis-Induced Acute Lung Injury by Activating the Nrf2\/HO-1 Pathway and Inhibiting Ferroptosis","volume":"60","author":"Tang","year":"2022","journal-title":"Pharm. Biol."},{"key":"ref_135","doi-asserted-by":"crossref","first-page":"121127","DOI":"10.1016\/j.lfs.2022.121127","article-title":"Naringenin Attenuates Inflammation, Apoptosis, and Ferroptosis in Silver Nanoparticle-Induced Lung Injury through a Mechanism Associated with Nrf2\/HO-1 Axis: In Vitro and in Vivo Studies","volume":"311","author":"Zhang","year":"2022","journal-title":"Life Sci."},{"key":"ref_136","doi-asserted-by":"crossref","first-page":"154102","DOI":"10.1016\/j.phymed.2022.154102","article-title":"Agrimonolide Inhibits Cancer Progression and Induces Ferroptosis and Apoptosis by Targeting SCD1 in Ovarian Cancer Cells","volume":"101","author":"Liu","year":"2022","journal-title":"Phytomedicine"},{"key":"ref_137","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1139\/bcb-2021-0399","article-title":"Alloimperatorin Activates Apoptosis, Ferroptosis, and Oxeiptosis to Inhibit the Growth and Invasion of Breast Cancer Cells in Vitro","volume":"100","author":"Zhang","year":"2022","journal-title":"Biochem. Cell Biol."},{"key":"ref_138","doi-asserted-by":"crossref","unstructured":"Liu, R., Rong, G., Liu, Y., Huang, W., He, D., and Lu, R. (2021). Delivery of Apigenin-Loaded Magnetic Fe2O3\/Fe3O4@mSiO2 Nanocomposites to A549 Cells and Their Antitumor Mechanism. Mater. Sci. Eng. C Mater. Biol. Appl., 120.","DOI":"10.1016\/j.msec.2020.111719"},{"key":"ref_139","doi-asserted-by":"crossref","first-page":"1783485","DOI":"10.1155\/2021\/1783485","article-title":"Bavachin Induces Ferroptosis through the STAT3\/P53\/SLC7A11 Axis in Osteosarcoma Cells","volume":"2021","author":"Luo","year":"2021","journal-title":"Oxidative Med. Cell. Longev."},{"key":"ref_140","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1021\/acs.jnatprod.2c00959","article-title":"Ginkgo Biflavones Cause P53 Wild-Type Dependent Cell Death in a Transcription-Independent Manner of P53","volume":"86","author":"Zhang","year":"2023","journal-title":"J. Nat. Prod."},{"key":"ref_141","doi-asserted-by":"crossref","unstructured":"Zhou, L., Yang, C., Zhong, W., Wang, Q., Zhang, D., Zhang, J., Xie, S., and Xu, M. (2021). Chrysin Induces Autophagy-Dependent Ferroptosis to Increase Chemosensitivity to Gemcitabine by Targeting CBR1 in Pancreatic Cancer Cells. Biochem. Pharmacol., 193.","DOI":"10.1016\/j.bcp.2021.114813"},{"key":"ref_142","doi-asserted-by":"crossref","first-page":"3469840","DOI":"10.1155\/2020\/3469840","article-title":"Transcriptome Investigation and In Vitro Verification of Curcumin-Induced HO-1 as a Feature of Ferroptosis in Breast Cancer Cells","volume":"2020","author":"Li","year":"2020","journal-title":"Oxidative Med. Cell. Longev."},{"key":"ref_143","doi-asserted-by":"crossref","first-page":"1951","DOI":"10.1080\/15384101.2023.2247248","article-title":"3,5-diCQA Suppresses Colorectal Cancer Cell Growth through ROS\/AMPK\/mTOR Mediated Mitochondrial Dysfunction and Ferroptosis","volume":"22","author":"Wang","year":"2023","journal-title":"Cell Cycle"},{"key":"ref_144","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.freeradbiomed.2022.06.010","article-title":"Flavonoid 4,4\u2032-Dimethoxychalcone Induced Ferroptosis in Cancer Cells by Synergistically Activating Keap1\/Nrf2\/HMOX1 Pathway and Inhibiting FECH","volume":"188","author":"Yang","year":"2022","journal-title":"Free Radic. Biol. Med."},{"key":"ref_145","doi-asserted-by":"crossref","unstructured":"Oh, E.S., Ryu, H.W., Song, Y.N., Kang, M.-J., Huh, Y.H., Park, J.-Y., Oh, S.M., Lee, S.-Y., Park, Y.J., and Kim, D.-Y. (2023). Diplacone Isolated from Paulownia Tomentosa Mature Fruit Induces Ferroptosis-Mediated Cell Death through Mitochondrial Ca2+ Influx and Mitochondrial Permeability Transition. Int. J. Mol. Sci., 24.","DOI":"10.3390\/ijms24087057"},{"key":"ref_146","doi-asserted-by":"crossref","first-page":"1702","DOI":"10.1002\/jat.4509","article-title":"Emodin Disrupts the Notch1\/Nrf2\/GPX4 Antioxidant System and Promotes Renal Cell Ferroptosis","volume":"43","author":"Xing","year":"2023","journal-title":"J. Appl. Toxicol."},{"key":"ref_147","doi-asserted-by":"crossref","first-page":"10089","DOI":"10.18632\/aging.205049","article-title":"Eriocitrin Inhibits Epithelial-Mesenchymal Transformation (EMT) in Lung Adenocarcinoma Cells via Triggering Ferroptosis","volume":"15","author":"Gao","year":"2023","journal-title":"Aging"},{"key":"ref_148","doi-asserted-by":"crossref","unstructured":"Wang, X., Chen, J., Tie, H., Tian, W., Zhao, Y., Qin, L., Guo, S., Li, Q., and Bao, C. (2023). Eriodictyol Regulated Ferroptosis, Mitochondrial Dysfunction, and Cell Viability via Nrf2\/HO-1\/NQO1 Signaling Pathway in Ovarian Cancer Cells. J. Biochem. Mol. Toxicol., 37.","DOI":"10.1002\/jbt.23368"},{"key":"ref_149","doi-asserted-by":"crossref","first-page":"611","DOI":"10.2147\/JHC.S395617","article-title":"Inhibitory Effects of Esculetin on Liver Cancer Through Triggering NCOA4 Pathway-Mediation Ferritinophagy in Vivo and in Vitro","volume":"10","author":"Xiu","year":"2023","journal-title":"J. Hepatocell. Carcinoma"},{"key":"ref_150","doi-asserted-by":"crossref","first-page":"4607966","DOI":"10.1155\/2022\/4607966","article-title":"Ferulic Acid Mitigates Growth and Invasion of Esophageal Squamous Cell Carcinoma through Inducing Ferroptotic Cell Death","volume":"2022","author":"Cao","year":"2022","journal-title":"Dis. Markers"},{"key":"ref_151","doi-asserted-by":"crossref","unstructured":"Xie, J., Wang, H., Xie, W., Liu, Y., and Chen, Y. (2023). Gallic Acid Promotes Ferroptosis in Hepatocellular Carcinoma via Inactivating Wnt\/\u03b2-Catenin Signaling Pathway. Naunyn Schmiedebergs Arch. Pharmacol., in press.","DOI":"10.1007\/s00210-023-02770-5"},{"key":"ref_152","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/s12935-020-1100-y","article-title":"Anti-Cancer Effect of Gallic Acid in Presence of Low Level Laser Irradiation: ROS Production and Induction of Apoptosis and Ferroptosis","volume":"20","author":"Khorsandi","year":"2020","journal-title":"Cancer Cell Int."},{"key":"ref_153","doi-asserted-by":"crossref","unstructured":"Tang, H.M., and Cheung, P.C.K. (2019). Gallic Acid Triggers Iron-Dependent Cell Death with Apoptotic, Ferroptotic, and Necroptotic Features. Toxins, 11.","DOI":"10.3390\/toxins11090492"},{"key":"ref_154","doi-asserted-by":"crossref","unstructured":"Liu, Z., Wang, X., Li, J., Yang, X., Huang, J., Ji, C., Li, X., Li, L., Zhou, J., and Hu, Y. (2023). Gambogenic Acid Induces Cell Death in Human Osteosarcoma through Altering Iron Metabolism, Disturbing the Redox Balance, and Activating the P53 Signaling Pathway. Chem. Biol. Interact., 382.","DOI":"10.1016\/j.cbi.2023.110602"},{"key":"ref_155","doi-asserted-by":"crossref","first-page":"115110","DOI":"10.1016\/j.taap.2020.115110","article-title":"Gambogenic Acid Induces Ferroptosis in Melanoma Cells Undergoing Epithelial-to-Mesenchymal Transition","volume":"401","author":"Wang","year":"2020","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"ref_156","doi-asserted-by":"crossref","first-page":"187","DOI":"10.3892\/ol.2022.13307","article-title":"6-Gingerol Suppresses Cell Viability, Migration and Invasion via Inhibiting EMT, and Inducing Autophagy and Ferroptosis in LPS-Stimulated and LPS-Unstimulated Prostate Cancer Cells","volume":"23","author":"Liu","year":"2022","journal-title":"Oncol. Lett."},{"key":"ref_157","doi-asserted-by":"crossref","first-page":"598555","DOI":"10.3389\/fphar.2020.598555","article-title":"The Inhibitory Effect of 6-Gingerol on Ubiquitin-Specific Peptidase 14 Enhances Autophagy-Dependent Ferroptosis and Anti-Tumor in Vivo and in Vitro","volume":"11","author":"Tsai","year":"2020","journal-title":"Front. Pharmacol."},{"key":"ref_158","doi-asserted-by":"crossref","first-page":"153370","DOI":"10.1016\/j.phymed.2020.153370","article-title":"Ginkgetin Derived from Ginkgo Biloba Leaves Enhances the Therapeutic Effect of Cisplatin via Ferroptosis-Mediated Disruption of the Nrf2\/HO-1 Axis in EGFR Wild-Type Non-Small-Cell Lung Cancer","volume":"80","author":"Lou","year":"2021","journal-title":"Phytomedicine"},{"key":"ref_159","doi-asserted-by":"crossref","first-page":"897791","DOI":"10.3389\/fphar.2022.897791","article-title":"Honokiol Induces Ferroptosis by Upregulating HMOX1 in Acute Myeloid Leukemia Cells","volume":"13","author":"Lai","year":"2022","journal-title":"Front. Pharmacol."},{"key":"ref_160","first-page":"3039","article-title":"Honokiol Induces Ferroptosis in Colon Cancer Cells by Regulating GPX4 Activity","volume":"11","author":"Guo","year":"2021","journal-title":"Am. J. Cancer Res."},{"key":"ref_161","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1002\/biof.1927","article-title":"Effects of Icariin and Curcumol on Autophagy, Ferroptosis, and Lipid Metabolism Based on miR-7\/m-TOR\/SREBP1 Pathway on Prostate Cancer","volume":"49","author":"Xu","year":"2023","journal-title":"Biofactors"},{"key":"ref_162","doi-asserted-by":"crossref","first-page":"154182","DOI":"10.1016\/j.phymed.2022.154182","article-title":"Icariside II Induces Ferroptosis in Renal Cell Carcinoma Cells by Regulating the miR-324-3p\/GPX4 Axis","volume":"102","author":"Yu","year":"2022","journal-title":"Phytomedicine"},{"key":"ref_163","doi-asserted-by":"crossref","first-page":"2210","DOI":"10.1097\/CM9.0000000000002675","article-title":"Isoliquiritigenin Induces HMOX1 and GPX4-Mediated Ferroptosis in Gallbladder Cancer Cells","volume":"136","author":"Wang","year":"2023","journal-title":"Chin. Med. J."},{"key":"ref_164","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1080\/08923973.2023.2165943","article-title":"Isoliquiritin Modulates Ferroptosis via NF-\u03baB Signaling Inhibition and Alleviates Doxorubicin Resistance in Breast Cancer","volume":"45","author":"Wang","year":"2023","journal-title":"Immunopharmacol. Immunotoxicol."},{"key":"ref_165","doi-asserted-by":"crossref","first-page":"175853","DOI":"10.1016\/j.ejphar.2023.175853","article-title":"Isoorientin Reverses Lung Cancer Drug Resistance by Promoting Ferroptosis via the SIRT6\/Nrf2\/GPX4 Signaling Pathway","volume":"954","author":"Feng","year":"2023","journal-title":"Eur. J. Pharmacol."},{"key":"ref_166","doi-asserted-by":"crossref","unstructured":"Luo, X., Gong, Y., Jiang, Q., Wang, Q., Li, S., and Liu, L. (2023). Isoquercitrin Promotes Ferroptosis and Oxidative Stress in Nasopharyngeal Carcinoma via the AMPK\/NF-\u03baB Pathway. J. Biochem. Mol. Toxicol., 38.","DOI":"10.1002\/jbt.23542"},{"key":"ref_167","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1002\/pros.24642","article-title":"Luteolin Induces Ferroptosis in Prostate Cancer Cells by Promoting TFEB Nuclear Translocation and Increasing Ferritinophagy","volume":"84","author":"Fu","year":"2023","journal-title":"Prostate"},{"key":"ref_168","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1016\/j.freeradbiomed.2023.09.014","article-title":"Luteolin Exhibits Synergistic Therapeutic Efficacy with Erastin to Induce Ferroptosis in Colon Cancer Cells through the HIC1-Mediated Inhibition of GPX4 Expression","volume":"208","author":"Zheng","year":"2023","journal-title":"Free Radic. Biol. Med."},{"key":"ref_169","doi-asserted-by":"crossref","first-page":"1366957","DOI":"10.1155\/2022\/1366957","article-title":"Lysionotin Induces Ferroptosis to Suppress Development of Colorectal Cancer via Promoting Nrf2 Degradation","volume":"2022","author":"Gao","year":"2022","journal-title":"Oxidative Med. Cell. Longev."},{"key":"ref_170","doi-asserted-by":"crossref","first-page":"865073","DOI":"10.3389\/fgene.2022.865073","article-title":"Nobiletin Induces Ferroptosis in Human Skin Melanoma Cells Through the GSK3\u03b2-Mediated Keap1\/Nrf2\/HO-1 Signalling Pathway","volume":"13","author":"Feng","year":"2022","journal-title":"Front. Genet."},{"key":"ref_171","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1080\/01635581.2023.2216922","article-title":"Puerarin Induces Ferroptosis in Colorectal Cancer Cells via Triggering NCOA4 Upregulation","volume":"75","author":"Lian","year":"2023","journal-title":"Nutr. Cancer"},{"key":"ref_172","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.freeradbiomed.2023.03.263","article-title":"Plumbagin Is a Novel GPX4 Protein Degrader That Induces Apoptosis in Hepatocellular Carcinoma Cells","volume":"203","author":"Yao","year":"2023","journal-title":"Free Radic. Biol. Med."},{"key":"ref_173","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1186\/s40001-022-00934-2","article-title":"Quercetin Inhibits the Progression of Endometrial HEC-1-A Cells by Regulating Ferroptosis-a Preliminary Study","volume":"27","author":"Li","year":"2022","journal-title":"Eur. J. Med. Res."},{"key":"ref_174","doi-asserted-by":"crossref","first-page":"131","DOI":"10.14715\/cmb\/2023.69.7.21","article-title":"Resveratrol Drives Ferroptosis of Acute Myeloid Leukemia Cells through Hsa-miR-335-5p\/NFS1\/GPX4 Pathway in a ROS-Dependent Manner","volume":"69","author":"Liu","year":"2023","journal-title":"Cell. Mol. Biol."},{"key":"ref_175","doi-asserted-by":"crossref","unstructured":"Shan, G., Minchao, K., Jizhao, W., Rui, Z., Guangjian, Z., Jin, Z., and Meihe, L. (2023). Resveratrol Improves the Cytotoxic Effect of CD8 +T Cells in the Tumor Microenvironment by Regulating HMMR\/Ferroptosis in Lung Squamous Cell Carcinoma. J. Pharm. Biomed. Anal., 229.","DOI":"10.1016\/j.jpba.2023.115346"},{"key":"ref_176","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1620\/tjem.2022.J061","article-title":"Rhamnazin Inhibits Hepatocellular Carcinoma Cell Aggressiveness in Vitro via Glutathione Peroxidase 4-Dependent Ferroptosis","volume":"258","author":"Mei","year":"2022","journal-title":"Tohoku J. Exp. Med."},{"key":"ref_177","doi-asserted-by":"crossref","unstructured":"Xie, Y., Zhou, X., Li, J., Yao, X.-C., Liu, W.-L., Kang, F.-H., Zou, Z.-X., Xu, K.-P., Xu, P.-S., and Tan, G.-S. (2021). Identification of a New Natural Biflavonoids against Breast Cancer Cells Induced Ferroptosis via the Mitochondrial Pathway. Bioorganic Chem., 109.","DOI":"10.1016\/j.bioorg.2021.104744"},{"key":"ref_178","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1021\/acschemneuro.2c00308","article-title":"Mitochondrial Inhibitor Rotenone Triggers and Enhances Neuronal Ferroptosis Following Intracerebral Hemorrhage","volume":"14","author":"Cheng","year":"2023","journal-title":"ACS Chem. Neurosci."},{"key":"ref_179","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.7150\/ijms.74569","article-title":"Rotenone, an Environmental Toxin, Causes Abnormal Methylation of the Mouse Brain Organoid\u2019s Genome and Ferroptosis","volume":"19","author":"Huang","year":"2022","journal-title":"Int. J. Med. Sci."},{"key":"ref_180","doi-asserted-by":"crossref","first-page":"153576","DOI":"10.1016\/j.prp.2021.153576","article-title":"Resveratrol Attenuates Rotenone-Induced Inflammation and Oxidative Stress via STAT1 and Nrf2\/Keap1\/SLC7A11 Pathway in a Microglia Cell Line","volume":"225","author":"Sun","year":"2021","journal-title":"Pathol. Res. Pract."},{"key":"ref_181","doi-asserted-by":"crossref","first-page":"973611","DOI":"10.3389\/fphar.2022.973611","article-title":"S-3\u2032-Hydroxy-7\u2032, 2\u2032, 4\u2032-Trimethoxyisoxane, a Novel Ferroptosis Inducer, Promotes NSCLC Cell Death through Inhibiting Nrf2\/HO-1 Signaling Pathway","volume":"13","author":"Chen","year":"2022","journal-title":"Front. Pharmacol."},{"key":"ref_182","doi-asserted-by":"crossref","first-page":"2083","DOI":"10.2147\/DDDT.S364441","article-title":"Shikonin Could Be Used to Treat Tubal Pregnancy via Enhancing Ferroptosis Sensitivity","volume":"16","author":"Lai","year":"2022","journal-title":"Drug Des. Dev. Ther."},{"key":"ref_183","doi-asserted-by":"crossref","first-page":"1025067","DOI":"10.3389\/fonc.2022.1025067","article-title":"Shikonin Induces Ferroptosis in Multiple Myeloma via GOT1-Mediated Ferritinophagy","volume":"12","author":"Li","year":"2022","journal-title":"Front. Oncol."},{"key":"ref_184","doi-asserted-by":"crossref","first-page":"e2101926","DOI":"10.1002\/adhm.202101926","article-title":"Fe(III)-Shikonin Supramolecular Nanomedicine for Combined Therapy of Tumor via Ferroptosis and Necroptosis","volume":"11","author":"Feng","year":"2022","journal-title":"Adv. Healthc. Mater."},{"key":"ref_185","doi-asserted-by":"crossref","first-page":"8966368","DOI":"10.1155\/2022\/8966368","article-title":"Theaflavin-3,3\u2032-Digallate Plays a ROS-Mediated Dual Role in Ferroptosis and Apoptosis via the MAPK Pathway in Human Osteosarcoma Cell Lines and Xenografts","volume":"2022","author":"He","year":"2022","journal-title":"Oxidative Med. Cell. Longev."},{"key":"ref_186","doi-asserted-by":"crossref","first-page":"102116","DOI":"10.1016\/j.tice.2023.102116","article-title":"Tiliroside Induces Ferroptosis to Repress the Development of Triple-Negative Breast Cancer Cells","volume":"83","author":"Hu","year":"2023","journal-title":"Tissue Cell"},{"key":"ref_187","doi-asserted-by":"crossref","first-page":"154668","DOI":"10.1016\/j.phymed.2023.154668","article-title":"Tiliroside Targets TBK1 to Induce Ferroptosis and Sensitize Hepatocellular Carcinoma to Sorafenib","volume":"111","author":"Yang","year":"2023","journal-title":"Phytomedicine"},{"key":"ref_188","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.bbrc.2022.12.014","article-title":"The Natural Flavone Acacetin Protects against High-Fat Diet-Induced Lipid Accumulation in the Liver via the Endoplasmic Reticulum Stress\/Ferroptosis Pathway","volume":"640","author":"Jiang","year":"2023","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"ref_189","doi-asserted-by":"crossref","first-page":"202","DOI":"10.3892\/mmr.2023.13089","article-title":"Acetyl Zingerone Ameliorates Osteoarthritis by Inhibiting Chondrocyte Programmed Cell Death","volume":"28","author":"Chen","year":"2023","journal-title":"Mol. Med. Rep."},{"key":"ref_190","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.freeradbiomed.2023.06.025","article-title":"Aloe-Emodin Alleviates Doxorubicin-Induced Cardiotoxicity via Inhibition of Ferroptosis","volume":"206","author":"He","year":"2023","journal-title":"Free Radic. Biol. Med."},{"key":"ref_191","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.freeradbiomed.2021.12.262","article-title":"Hydroxysafflor Yellow A and Anhydrosafflor Yellow B Alleviate Ferroptosis and Parthanatos in PC12 Cells Injured by OGD\/R","volume":"179","author":"Chen","year":"2022","journal-title":"Free Radic. Biol. Med."},{"key":"ref_192","doi-asserted-by":"crossref","first-page":"113089","DOI":"10.1016\/j.fct.2022.113089","article-title":"Apigenin Ameliorates Di(2-Ethylhexyl) Phthalate-Induced Ferroptosis: The Activation of Glutathione Peroxidase 4 and Suppression of Iron Intake","volume":"164","author":"Han","year":"2022","journal-title":"Food Chem. Toxicol."},{"key":"ref_193","doi-asserted-by":"crossref","unstructured":"Chen, B., Li, X., Ouyang, X., Liu, J., Liu, Y., and Chen, D. (2021). Comparison of Ferroptosis-Inhibitory Mechanisms between Ferrostatin-1 and Dietary Stilbenes (Piceatannol and Astringin). Molecules, 26.","DOI":"10.3390\/molecules26041092"},{"key":"ref_194","doi-asserted-by":"crossref","first-page":"3326","DOI":"10.1111\/jcmm.17905","article-title":"Avicularin Alleviates Acute Liver Failure by Regulation of the TLR4\/MyD88\/NF-\u03baB and Nrf2\/HO-1\/GPX4 Pathways to Reduce Inflammation and Ferroptosis","volume":"27","author":"Shi","year":"2023","journal-title":"J. Cell. Mol. Med."},{"key":"ref_195","doi-asserted-by":"crossref","first-page":"1568","DOI":"10.1111\/cbdd.14349","article-title":"Baicalein, a Component of Banxia Xiexin Decoction, Alleviates CPT-11-Induced Gastrointestinal Dysfunction by Inhibiting ALOX15-Mediated Ferroptosis","volume":"102","author":"Pei","year":"2023","journal-title":"Chem. Biol. Drug Des."},{"key":"ref_196","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1097\/SHK.0000000000002058","article-title":"Baicalein Relieves Brain Injury via Inhibiting Ferroptosis and Endoplasmic Reticulum Stress in a Rat Model of Cardiac Arrest","volume":"59","author":"Ye","year":"2023","journal-title":"Shock"},{"key":"ref_197","doi-asserted-by":"crossref","unstructured":"Yu, M., Li, H., Wang, B., Wu, Z., Wu, S., Jiang, G., Wang, H., and Huang, Y. (2023). Baicalein Ameliorates Polymyxin B-Induced Acute Renal Injury by Inhibiting Ferroptosis via Regulation of SIRT1\/P53 Acetylation. Chem. Biol. Interact., 382.","DOI":"10.1016\/j.cbi.2023.110607"},{"key":"ref_198","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.freeradbiomed.2023.01.006","article-title":"Baicalein Limits Osteoarthritis Development by Inhibiting Chondrocyte Ferroptosis","volume":"196","author":"Wan","year":"2023","journal-title":"Free Radic. Biol. Med."},{"key":"ref_199","doi-asserted-by":"crossref","first-page":"6189","DOI":"10.3390\/cimb44120422","article-title":"Baicalein Relieves Ferroptosis-Mediated Phagocytosis Inhibition of Macrophages in Ovarian Endometriosis","volume":"44","author":"Yi","year":"2022","journal-title":"Curr. Issues Mol. Biol."},{"key":"ref_200","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.bbrc.2021.05.010","article-title":"Baicalein Inhibits RLS3-Induced Ferroptosis in Melanocytes","volume":"561","author":"Yang","year":"2021","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"ref_201","doi-asserted-by":"crossref","first-page":"628988","DOI":"10.3389\/fphar.2021.628988","article-title":"Baicalin Prevents Myocardial Ischemia\/Reperfusion Injury Through Inhibiting ACSL4 Mediated Ferroptosis","volume":"12","author":"Fan","year":"2021","journal-title":"Front. Pharmacol."},{"key":"ref_202","doi-asserted-by":"crossref","unstructured":"He, Q., Yang, J., Pan, Z., Zhang, G., Chen, B., Li, S., Xiao, J., Tan, F., Wang, Z., and Chen, P. (2023). Biochanin A Protects against Iron Overload Associated Knee Osteoarthritis via Regulating Iron Levels and NRF2\/System Xc-\/GPX4 Axis. Biomed. Pharmacothery, 157.","DOI":"10.1016\/j.biopha.2022.113915"},{"key":"ref_203","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.freeradbiomed.2022.01.001","article-title":"Cannabinol Inhibits Oxytosis\/Ferroptosis by Directly Targeting Mitochondria Independently of Cannabinoid Receptors","volume":"180","author":"Liang","year":"2022","journal-title":"Free Radic. Biol. Med."},{"key":"ref_204","doi-asserted-by":"crossref","unstructured":"Liu, H., Zhao, Z., Yan, M., Zhang, Q., Jiang, T., and Xue, J. (2023). Calycosin Decreases Cerebral Ischemia\/Reperfusion Injury by Suppressing ACSL4-Dependent Ferroptosis. Arch. Biochem. Biophys., 734.","DOI":"10.1016\/j.abb.2022.109488"},{"key":"ref_205","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1080\/13880209.2022.2067572","article-title":"Calycosin Plays a Protective Role in Diabetic Kidney Disease through the Regulation of Ferroptosis","volume":"60","author":"Huang","year":"2022","journal-title":"Pharm. Biol."},{"key":"ref_206","doi-asserted-by":"crossref","first-page":"52","DOI":"10.3892\/ijmm.2021.4885","article-title":"Carthamin Yellow Improves Cerebral Ischemia-reperfusion Injury by Attenuating Inflammation and Ferroptosis in Rats","volume":"47","author":"Guo","year":"2021","journal-title":"Int. J. Mol. Med."},{"key":"ref_207","doi-asserted-by":"crossref","unstructured":"Yang, L., Liu, Y., Zhang, W., Hua, Y., Chen, B., Wu, Q., Chen, D., Liu, S., and Li, X. (2021). Ferroptosis-Inhibitory Difference between Chebulagic Acid and Chebulinic Acid Indicates Beneficial Role of HHDP. Molecules, 26.","DOI":"10.3390\/molecules26144300"},{"key":"ref_208","doi-asserted-by":"crossref","first-page":"109435","DOI":"10.1016\/j.intimp.2022.109435","article-title":"Protective Effects of Chicoric Acid on LPS-Induced Endometritis in Mice via Inhibiting Ferroptosis by Nrf2\/HO-1 Signal Axis","volume":"113","author":"Wang","year":"2022","journal-title":"Int. Immunopharmacol."},{"key":"ref_209","doi-asserted-by":"crossref","first-page":"568","DOI":"10.4103\/1673-5374.350203","article-title":"Chlorogenic Acid Alleviates Hypoxic-Ischemic Brain Injury in Neonatal Mice","volume":"18","author":"Li","year":"2023","journal-title":"Neural Regen. Res."},{"key":"ref_210","doi-asserted-by":"crossref","first-page":"116479","DOI":"10.1016\/j.taap.2023.116479","article-title":"Chlorogenic Acid, Rutin, and Quercetin from Lysimachia Christinae Alleviate Triptolide-Induced Multi-Organ Injury in Vivo by Modulating Immunity and AKT\/mTOR Signal Pathway to Inhibit Ferroptosis and Apoptosis","volume":"467","author":"Wu","year":"2023","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"ref_211","doi-asserted-by":"crossref","first-page":"4353","DOI":"10.1021\/acs.jafc.2c01196","article-title":"Chlorogenic Acid Alleviates Chronic Stress-Induced Duodenal Ferroptosis via the Inhibition of the IL-6\/JAK2\/STAT3 Signaling Pathway in Rats","volume":"70","author":"Zhao","year":"2022","journal-title":"J. Agric. Food Chem."},{"key":"ref_212","doi-asserted-by":"crossref","unstructured":"Shang, J., Jiao, J., Yan, M., Wang, J., Li, Q., Shabuerjiang, L., Lu, Y., Song, Q., Bi, L., and Huang, G. (2023). Chrysin Protects against Cerebral Ischemia-Reperfusion Injury in Hippocampus via Restraining Oxidative Stress and Transition Elements. Biomed. Pharmacother., 161.","DOI":"10.1016\/j.biopha.2023.114534"},{"key":"ref_213","doi-asserted-by":"crossref","first-page":"122176","DOI":"10.1016\/j.lfs.2023.122176","article-title":"Corilagin Attenuates Intestinal Ischemia\/Reperfusion Injury in Mice by Inhibiting Ferritinophagy-Mediated Ferroptosis through Disrupting NCOA4-Ferritin Interaction","volume":"334","author":"Wang","year":"2023","journal-title":"Life Sci."},{"key":"ref_214","doi-asserted-by":"crossref","first-page":"118356","DOI":"10.1016\/j.lfs.2020.118356","article-title":"Curculigoside Inhibits Ferroptosis in Ulcerative Colitis through the Induction of GPX4","volume":"259","author":"Wang","year":"2020","journal-title":"Life Sci."},{"key":"ref_215","doi-asserted-by":"crossref","first-page":"102114","DOI":"10.1016\/j.tice.2023.102114","article-title":"LoxBlock-1 or Curcumin Attenuates Liver, Pancreas and Cardiac Ferroptosis, Oxidative Stress and Injury in Ischemia\/Reperfusion-Damaged Rats by Facilitating ACSL\/GPx4 Signaling","volume":"82","author":"Kar","year":"2023","journal-title":"Tissue Cell"},{"key":"ref_216","doi-asserted-by":"crossref","first-page":"154539","DOI":"10.1016\/j.phymed.2022.154539","article-title":"Protective Effect of Curcumin on Hepatolenticular Degeneration through Copper Excretion and Inhibition of Ferroptosis","volume":"113","author":"Sun","year":"2023","journal-title":"Phytomedicine"},{"key":"ref_217","doi-asserted-by":"crossref","unstructured":"Wang, Y., Lin, H., Huang, W., Liu, Z., Chen, Z., Zhao, X., Ding, T., Qin, W., and Shen, Y. (2023). Curcumin Attenuates Periodontal Injury via Inhibiting Ferroptosis of Ligature-Induced Periodontitis in Mice. Int. J. Mol. Sci., 24.","DOI":"10.3390\/ijms24129835"},{"key":"ref_218","doi-asserted-by":"crossref","unstructured":"Wu, L., Dong, B., Chen, Q., Wang, Y., Han, D., Zhu, X., Liu, H., Zhang, Z., Yang, Y., and Xie, S. (2023). Effects of Curcumin on Oxidative Stress and Ferroptosis in Acute Ammonia Stress-Induced Liver Injury in Gibel Carp (Carassius Gibelio). Int. J. Mol. Sci., 24.","DOI":"10.3390\/ijms24076441"},{"key":"ref_219","doi-asserted-by":"crossref","first-page":"e20163","DOI":"10.1016\/j.heliyon.2023.e20163","article-title":"Curcumin Reverses Erastin-Induced Chondrocyte Ferroptosis by Upregulating Nrf2","volume":"9","author":"Zhou","year":"2023","journal-title":"Heliyon"},{"key":"ref_220","doi-asserted-by":"crossref","unstructured":"Olanlokun, J.O., Abiodun, W.O., Ebenezer, O., Koorbanally, N.A., and Olorunsogo, O.O. (2022). Curcumin Modulates Multiple Cell Death, Matrix Metalloproteinase Activation and Cardiac Protein Release in Susceptible and Resistant Plasmodium Berghei-Infected Mice. Biomed. Pharmacother., 146.","DOI":"10.1016\/j.biopha.2021.112454"},{"key":"ref_221","doi-asserted-by":"crossref","first-page":"S753","DOI":"10.1177\/09603271211059497","article-title":"Effect of Curcumin on Lung Epithelial Injury and Ferroptosis Induced by Cigarette Smoke","volume":"40","author":"Tang","year":"2021","journal-title":"Hum. Exp. Toxicol."},{"key":"ref_222","doi-asserted-by":"crossref","first-page":"8049","DOI":"10.2147\/IJN.S334965","article-title":"Curcumin Nanoparticles Inhibiting Ferroptosis for the Enhanced Treatment of Intracerebral Hemorrhage","volume":"16","author":"Yang","year":"2021","journal-title":"Int. J. Nanomed."},{"key":"ref_223","doi-asserted-by":"crossref","first-page":"8961","DOI":"10.1096\/fj.201900077R","article-title":"Curcumin Reduces Renal Damage Associated with Rhabdomyolysis by Decreasing Ferroptosis-Mediated Cell Death","volume":"33","author":"Herencia","year":"2019","journal-title":"FASEB J."},{"key":"ref_224","doi-asserted-by":"crossref","unstructured":"Kose, T., Vera-Aviles, M., Sharp, P.A., and Latunde-Dada, G.O. (2019). Curcumin and (\u2212)- Epigallocatechin-3-Gallate Protect Murine MIN6 Pancreatic Beta-Cells against Iron Toxicity and Erastin-Induced Ferroptosis. Pharmaceuticals, 12.","DOI":"10.3390\/ph12010026"},{"key":"ref_225","doi-asserted-by":"crossref","first-page":"4404","DOI":"10.1039\/C8FO00466H","article-title":"Curcumin Attenuates Doxorubicin-Induced Cardiotoxicity via Suppressing Oxidative Stress and Preventing Mitochondrial Dysfunction Mediated by 14-3-3\u03b3","volume":"9","author":"He","year":"2018","journal-title":"Food Funct."},{"key":"ref_226","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/s10020-023-00642-5","article-title":"Cyanidin-3-Glucoside Inhibits Ferroptosis in Renal Tubular Cells after Ischemia\/Reperfusion Injury via the AMPK Pathway","volume":"29","author":"Du","year":"2023","journal-title":"Mol. Med."},{"key":"ref_227","doi-asserted-by":"crossref","unstructured":"Zhang, P., Rong, K., Guo, J., Cui, L., Kong, K., Zhao, C., Yang, H., Xu, H., Qin, A., and Ma, P. (2023). Cynarin Alleviates Intervertebral Disc Degeneration via Protecting Nucleus Pulposus Cells from Ferroptosis. Biomed. Pharmacother., 165.","DOI":"10.1016\/j.biopha.2023.115252"},{"key":"ref_228","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/j.chom.2023.04.002","article-title":"Liberation of Daidzein by Gut Microbial \u03b2-Galactosidase Suppresses Acetaminophen-Induced Hepatotoxicity in Mice","volume":"31","author":"Zeng","year":"2023","journal-title":"Cell Host Microbe"},{"key":"ref_229","doi-asserted-by":"crossref","first-page":"154756","DOI":"10.1016\/j.phymed.2023.154756","article-title":"Dihydromyricetin Attenuates Intracerebral Hemorrhage by Reversing the Effect of LCN2 via the System Xc- Pathway","volume":"115","author":"Liu","year":"2023","journal-title":"Phytomedicine"},{"key":"ref_230","doi-asserted-by":"crossref","first-page":"116595","DOI":"10.1016\/j.taap.2023.116595","article-title":"Dihydromyricetin Attenuates Cisplatin-Induced Acute Kidney Injury by Reducing Oxidative Stress, Inflammation and Ferroptosis","volume":"473","author":"Xu","year":"2023","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"ref_231","doi-asserted-by":"crossref","first-page":"3071","DOI":"10.2147\/DDDT.S378786","article-title":"Dihydromyricetin Attenuates Cerebral Ischemia Reperfusion Injury by Inhibiting SPHK1\/mTOR Signaling and Targeting Ferroptosis","volume":"16","author":"Xie","year":"2022","journal-title":"Drug Des. Dev. Ther."},{"key":"ref_232","doi-asserted-by":"crossref","first-page":"397","DOI":"10.3892\/mmr.2021.12036","article-title":"Dihydromyricetin Inhibits Oxidative Stress and Apoptosis in Oxygen and Glucose Deprivation\/Reoxygenation-induced HT22 Cells by Activating the Nrf2\/HO-1 Pathway","volume":"23","author":"Zhang","year":"2021","journal-title":"Mol. Med. Rep."},{"key":"ref_233","doi-asserted-by":"crossref","first-page":"153894","DOI":"10.1016\/j.phymed.2021.153894","article-title":"Dihydroquercetin Suppresses Cigarette Smoke Induced Ferroptosis in the Pathogenesis of Chronic Obstructive Pulmonary Disease by Activating Nrf2-Mediated Pathway","volume":"96","author":"Liu","year":"2022","journal-title":"Phytomedicine"},{"key":"ref_234","doi-asserted-by":"crossref","first-page":"845600","DOI":"10.3389\/fphar.2022.845600","article-title":"Dihydroquercetin Attenuates Silica-Induced Pulmonary Fibrosis by Inhibiting Ferroptosis Signaling Pathway","volume":"13","author":"Yuan","year":"2022","journal-title":"Front. Pharmacol."},{"key":"ref_235","doi-asserted-by":"crossref","first-page":"e13082","DOI":"10.7717\/peerj.13082","article-title":"3,4-Dihydroxyphenylethyl Alcohol Glycoside Reduces Acetaminophen-Induced Acute Liver Failure in Mice by Inhibiting Hepatocyte Ferroptosis and Pyroptosis","volume":"10","author":"Liu","year":"2022","journal-title":"PeerJ"},{"key":"ref_236","doi-asserted-by":"crossref","first-page":"122060","DOI":"10.1016\/j.lfs.2023.122060","article-title":"Diosmetin Alleviates S. aureus-Induced Mastitis by Inhibiting SIRT1\/GPX4 Mediated Ferroptosis","volume":"331","author":"Zhao","year":"2023","journal-title":"Life Sci."},{"key":"ref_237","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.matbio.2023.03.007","article-title":"Echinatin Maintains Glutathione Homeostasis in Vascular Smooth Muscle Cells to Protect against Matrix Remodeling and Arterial Stiffening","volume":"119","author":"Zhang","year":"2023","journal-title":"Matrix Biol."},{"key":"ref_238","doi-asserted-by":"crossref","unstructured":"Wang, Y., Shen, Z., Pei, C., Zhao, S., Jia, N., Huang, D., Wang, X., Wu, Y., Shi, S., and He, Y. (2022). Eleutheroside B Ameliorated High Altitude Pulmonary Edema by Attenuating Ferroptosis and Necroptosis through Nrf2-Antioxidant Response Signaling. Biomed. Pharmacother., 156.","DOI":"10.1016\/j.biopha.2022.113982"},{"key":"ref_239","first-page":"7673","article-title":"Emodin Attenuates Diabetic Kidney Disease by Inhibiting Ferroptosis via Upregulating Nrf2 Expression","volume":"15","author":"Ji","year":"2023","journal-title":"Aging"},{"key":"ref_240","doi-asserted-by":"crossref","first-page":"102040","DOI":"10.1016\/j.tice.2023.102040","article-title":"Engeletin Alleviates Erastin-Induced Oxidative Stress and Protects against Ferroptosis via Nrf2\/Keap1 Pathway in Bone Marrow Mesenchymal Stem Cells","volume":"82","author":"Huang","year":"2023","journal-title":"Tissue Cell"},{"key":"ref_241","doi-asserted-by":"crossref","unstructured":"Li, F., Hao, S., Gao, J., and Jiang, P. (2023). EGCG Alleviates Obesity-Exacerbated Lung Cancer Progression by STAT1\/SLC7A11 Pathway and Gut Microbiota. J. Nutr. Biochem., 120.","DOI":"10.1016\/j.jnutbio.2023.109416"},{"key":"ref_242","doi-asserted-by":"crossref","unstructured":"Yang, C., Wu, A., Tan, L., Tang, D., Chen, W., Lai, X., Gu, K., Chen, J., Chen, D., and Tang, Q. (2023). Epigallocatechin-3-Gallate Alleviates Liver Oxidative Damage Caused by Iron Overload in Mice through Inhibiting Ferroptosis. Nutrients, 15.","DOI":"10.3390\/nu15081993"},{"key":"ref_243","doi-asserted-by":"crossref","first-page":"154999","DOI":"10.1016\/j.phymed.2023.154999","article-title":"EGCG Attenuated Acute Myocardial Infarction by Inhibiting Ferroptosis via miR-450b-5p\/ACSL4 Axis","volume":"119","author":"Yu","year":"2023","journal-title":"Phytomedicine"},{"key":"ref_244","doi-asserted-by":"crossref","unstructured":"He, H., Wang, L., Qiao, Y., Yang, B., Yin, D., and He, M. (2021). Epigallocatechin-3-Gallate Pretreatment Alleviates Doxorubicin-Induced Ferroptosis and Cardiotoxicity by Upregulating AMPK\u03b12 and Activating Adaptive Autophagy. Redox Biol., 48.","DOI":"10.1016\/j.redox.2021.102185"},{"key":"ref_245","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1515\/tnsci-2020-0119","article-title":"EGCG Modulates PKD1 and Ferroptosis to Promote Recovery in ST Rats","volume":"11","author":"Wang","year":"2020","journal-title":"Transl. Neurosci."},{"key":"ref_246","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.freeradbiomed.2020.10.012","article-title":"Green Tea Derivative (-)-Epigallocatechin-3-Gallate (EGCG) Confers Protection against Ionizing Radiation-Induced Intestinal Epithelial Cell Death Both in Vitro and in Vivo","volume":"161","author":"Xie","year":"2020","journal-title":"Free Radic. Biol. Med."},{"key":"ref_247","doi-asserted-by":"crossref","first-page":"5644","DOI":"10.1002\/jcb.27848","article-title":"Eriodictyol Inhibits High Glucose-Induced Oxidative Stress and Inflammation in Retinal Ganglial Cells","volume":"120","author":"Lv","year":"2019","journal-title":"J. Cell. Biochem."},{"key":"ref_248","doi-asserted-by":"crossref","first-page":"511","DOI":"10.33549\/physiolres.935040","article-title":"Farrerol Alleviates Hypoxic-Ischemic Encephalopathy by Inhibiting Ferroptosis in Neonatal Rats via the Nrf2 Pathway","volume":"72","author":"Li","year":"2023","journal-title":"Physiol. Res."},{"key":"ref_249","doi-asserted-by":"crossref","first-page":"3483","DOI":"10.1111\/jcmm.17388","article-title":"Farrerol Alleviates Collagenase-Induced Tendinopathy by Inhibiting Ferroptosis in Rats","volume":"26","author":"Wu","year":"2022","journal-title":"J. Cell. Mol. Med."},{"key":"ref_250","doi-asserted-by":"crossref","unstructured":"Kose, T., Sharp, P.A., and Latunde-Dada, G.O. (2022). Upregulation of Nrf2 Signalling and the Inhibition of Erastin-Induced Ferroptosis by Ferulic Acid in MIN6 Cells. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms232415886"},{"key":"ref_251","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1097\/FJC.0000000000001199","article-title":"Ferulic Acid Alleviates Myocardial Ischemia Reperfusion Injury Via Upregulating AMPK\u03b12 Expression-Mediated Ferroptosis Depression","volume":"79","author":"Liu","year":"2021","journal-title":"J. Cardiovasc. Pharmacol."},{"key":"ref_252","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1038\/s41401-023-01156-w","article-title":"Fisetin Ameliorates Fibrotic Kidney Disease in Mice via Inhibiting ACSL4-Mediated Tubular Ferroptosis","volume":"45","author":"Wang","year":"2023","journal-title":"Acta Pharmacol. Sin."},{"key":"ref_253","doi-asserted-by":"crossref","first-page":"808480","DOI":"10.3389\/fphar.2021.808480","article-title":"Fisetin Attenuates Doxorubicin-Induced Cardiomyopathy In Vivo and In Vitro by Inhibiting Ferroptosis Through SIRT1\/Nrf2 Signaling Pathway Activation","volume":"12","author":"Li","year":"2021","journal-title":"Front. Pharmacol."},{"key":"ref_254","doi-asserted-by":"crossref","first-page":"121331","DOI":"10.1016\/j.lfs.2022.121331","article-title":"Formononetin Ameliorates Ferroptosis-Associated Fibrosis in Renal Tubular Epithelial Cells and in Mice with Chronic Kidney Disease by Suppressing the Smad3\/ATF3\/SLC7A11 Signaling","volume":"315","author":"Zhu","year":"2023","journal-title":"Life Sci."},{"key":"ref_255","doi-asserted-by":"crossref","first-page":"1999","DOI":"10.1007\/s00011-023-01800-5","article-title":"Fraxetin Alleviates BLM-Induced Idiopathic Pulmonary Fibrosis by Inhibiting NCOA4-Mediated Epithelial Cell Ferroptosis","volume":"72","author":"Zhai","year":"2023","journal-title":"Inflamm. Res."},{"key":"ref_256","first-page":"10315","article-title":"Fraxetin Attenuates Ferroptosis in Myocardial Infarction via AKT\/Nrf2\/HO-1 Signaling","volume":"13","author":"Xu","year":"2021","journal-title":"Am. J. Transl. Res."},{"key":"ref_257","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1021\/acschemneuro.2c00532","article-title":"Gallic Acid Improves Comorbid Chronic Pain and Depression Behaviors by Inhibiting P2X7 Receptor-Mediated Ferroptosis in the Spinal Cord of Rats","volume":"14","author":"Yang","year":"2023","journal-title":"ACS Chem. Neurosci."},{"key":"ref_258","doi-asserted-by":"crossref","first-page":"117282","DOI":"10.1016\/j.jep.2023.117282","article-title":"Gastrodin Alleviates Cisplatin Nephrotoxicity by Inhibiting Ferroptosis via the SIRT1\/FOXO3A\/GPX4 Signaling Pathway","volume":"319","author":"Qiu","year":"2023","journal-title":"J. Ethnopharmacol."},{"key":"ref_259","doi-asserted-by":"crossref","unstructured":"Zhang, H., Yuan, B., Huang, H., Qu, S., Yang, S., and Zeng, Z. (2018). Gastrodin Induced HO-1 and Nrf2 up-Regulation to Alleviate H2O2-Induced Oxidative Stress in Mouse Liver Sinusoidal Endothelial Cells through P38 MAPK Phosphorylation. Braz. J. Med. Biol. Res., 51, Erratum in Braz. J. Med. Biol. Res.\u00a02019, 52, e7439erratum.","DOI":"10.1590\/1414-431x20197439erratum"},{"key":"ref_260","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1002\/open.202000255","article-title":"Ferroptosis-Inhibitory Effect and Possible Mechanisms of Ellagitannin Geraniin","volume":"10","author":"Chen","year":"2021","journal-title":"ChemistryOpen"},{"key":"ref_261","doi-asserted-by":"crossref","first-page":"12525","DOI":"10.1021\/acs.jafc.2c05262","article-title":"Gingerenone A Alleviates Ferroptosis in Secondary Liver Injury in Colitis Mice via Activating Nrf2-Gpx4 Signaling Pathway","volume":"70","author":"Chen","year":"2022","journal-title":"J. Agric. Food Chem."},{"key":"ref_262","doi-asserted-by":"crossref","first-page":"3027514","DOI":"10.1155\/2022\/3027514","article-title":"6-Gingerol Alleviates Ferroptosis and Inflammation of Diabetic Cardiomyopathy via the Nrf2\/HO-1 Pathway","volume":"2022","author":"Wu","year":"2022","journal-title":"Oxidative Med. Cell. Longev."},{"key":"ref_263","doi-asserted-by":"crossref","unstructured":"Yang, J., Wang, M., Zheng, S., Huang, R., Wen, G., Zhou, P., Wang, W., Zhou, S., Jiang, X., and Liu, S. (2023). Mesoporous Polydopamine Delivering 8-Gingerol for the Target and Synergistic Treatment to the Spinal Cord Injury. J. Nanobiotechnology, 21.","DOI":"10.1186\/s12951-023-01896-1"},{"key":"ref_264","doi-asserted-by":"crossref","unstructured":"Lin, J.-H., Yang, K.-T., Ting, P.-C., Luo, Y.-P., Lin, D.-J., Wang, Y.-S., and Chang, J.-C. (2021). Gossypol Acetic Acid Attenuates Cardiac Ischemia\/Reperfusion Injury in Rats via an Antiferroptotic Mechanism. Biomolecules, 11.","DOI":"10.3390\/biom11111667"},{"key":"ref_265","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1080\/15384101.2023.2200291","article-title":"Hesperidin Mitigates Oxidative Stress-Induced Ferroptosis in Nucleus Pulposus Cells via Nrf2\/NF-\u03baB Axis to Protect Intervertebral Disc from Degeneration","volume":"22","author":"Zhu","year":"2023","journal-title":"Cell Cycle"},{"key":"ref_266","doi-asserted-by":"crossref","first-page":"5787","DOI":"10.1002\/ptr.7984","article-title":"Honokiol Attenuates High Glucose-Induced Peripheral Neuropathy via Inhibiting Ferroptosis and Activating AMPK\/SIRT1\/PGC-1\u03b1 Pathway in Schwann Cells","volume":"37","author":"Hu","year":"2023","journal-title":"Phytother. Res."},{"key":"ref_267","doi-asserted-by":"crossref","unstructured":"Ge, C., Peng, Y., Li, J., Wang, L., Zhu, X., Wang, N., Yang, D., Zhou, X., and Chang, D. (2023). Hydroxysafflor Yellow A Alleviates Acute Myocardial Ischemia\/Reperfusion Injury in Mice by Inhibiting Ferroptosis via the Activation of the HIF-1\u03b1\/SLC7A11\/GPX4 Signaling Pathway. Nutrients, 15.","DOI":"10.3390\/nu15153411"},{"key":"ref_268","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1080\/13880209.2023.2225543","article-title":"Hydroxysafflor Yellow A Inhibits Endothelial Cell Ferroptosis in Diabetic Atherosclerosis Mice by Regulating miR-429\/SLC7A11","volume":"61","author":"Rong","year":"2023","journal-title":"Pharm. Biol."},{"key":"ref_269","doi-asserted-by":"crossref","first-page":"104984","DOI":"10.1016\/j.fitote.2021.104984","article-title":"Discovery of Phloroglucinols from Hypericum Japonicum as Ferroptosis Inhibitors","volume":"153","author":"Peng","year":"2021","journal-title":"Fitoterapia"},{"key":"ref_270","doi-asserted-by":"crossref","unstructured":"Choi, J., Choi, H., and Chung, J. (2023). Icariin Supplementation Suppresses the Markers of Ferroptosis and Attenuates the Progression of Nonalcoholic Steatohepatitis in Mice Fed a Methionine Choline-Deficient Diet. Int. J. Mol. Sci., 24.","DOI":"10.3390\/ijms241512510"},{"key":"ref_271","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1007\/s10495-023-01814-8","article-title":"Inhibition of Ferroptosis by Icariin Treatment Attenuates Excessive Ethanol Consumption-Induced Atrial Remodeling and Susceptibility to Atrial Fibrillation, Role of SIRT1","volume":"28","author":"Yu","year":"2023","journal-title":"Apoptosis"},{"key":"ref_272","doi-asserted-by":"crossref","first-page":"3951","DOI":"10.1002\/ptr.7854","article-title":"Icariin Alleviates Ferroptosis-Related Atherosclerosis by Promoting Autophagy in Xo-LDL-Induced Vascular Endothelial Cell Injury and Atherosclerotic Mice","volume":"37","author":"Wang","year":"2023","journal-title":"Phytother. Res."},{"key":"ref_273","doi-asserted-by":"crossref","first-page":"937502","DOI":"10.3389\/fphar.2022.937502","article-title":"Icariin Protects Vertebral Endplate Chondrocytes against Apoptosis and Degeneration via Activating Nrf-2\/HO-1 Pathway","volume":"13","author":"Shao","year":"2022","journal-title":"Front. Pharmacol."},{"key":"ref_274","doi-asserted-by":"crossref","first-page":"2966","DOI":"10.1002\/2211-5463.13276","article-title":"Icariin Inhibits Hypoxia\/Reoxygenation-Induced Ferroptosis of Cardiomyocytes via Regulation of the Nrf2\/HO-1 Signaling Pathway","volume":"11","author":"Liu","year":"2021","journal-title":"FEBS Open Bio"},{"key":"ref_275","doi-asserted-by":"crossref","first-page":"72","DOI":"10.3892\/etm.2020.9504","article-title":"Icariin Enhances Cell Survival in Lipopolysaccharide-Induced Synoviocytes by Suppressing Ferroptosis via the Xc-\/GPX4 Axis","volume":"21","author":"Luo","year":"2021","journal-title":"Exp. Ther. Med."},{"key":"ref_276","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1111\/bph.15961","article-title":"Icariside II Preconditioning Evokes Robust Neuroprotection against Ischaemic Stroke, by Targeting Nrf2 and the OXPHOS\/NF-\u03baB\/Ferroptosis Pathway","volume":"180","author":"Gao","year":"2023","journal-title":"Br. J. Pharmacol."},{"key":"ref_277","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1080\/0886022X.2021.2003208","article-title":"Isoliquiritigenin Attenuates Septic Acute Kidney Injury by Regulating Ferritinophagy-Mediated Ferroptosis","volume":"43","author":"Tang","year":"2021","journal-title":"Ren. Fail."},{"key":"ref_278","doi-asserted-by":"crossref","first-page":"108852","DOI":"10.1016\/j.intimp.2022.108852","article-title":"Isoliquiritin Apioside Relieves Intestinal Ischemia\/Reperfusion-Induced Acute Lung Injury by Blocking Hif-1\u03b1-Mediated Ferroptosis","volume":"108","author":"Zhongyin","year":"2022","journal-title":"Int. Immunopharmacol."},{"key":"ref_279","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.cbi.2018.02.017","article-title":"Isoquercetin Attenuates Oxidative Stress and Neuronal Apoptosis after Ischemia\/Reperfusion Injury via Nrf2-Mediated Inhibition of the NOX4\/ROS\/NF-\u03baB Pathway","volume":"284","author":"Dai","year":"2018","journal-title":"Chem. Biol. Interact."},{"key":"ref_280","doi-asserted-by":"crossref","first-page":"1993","DOI":"10.1007\/s10753-021-01476-1","article-title":"Isorhamnetin Alleviates High Glucose-Aggravated Inflammatory Response and Apoptosis in Oxygen-Glucose Deprivation and Reoxygenation-Induced HT22 Hippocampal Neurons Through Akt\/SIRT1\/Nrf2\/HO-1 Signaling Pathway","volume":"44","author":"Wu","year":"2021","journal-title":"Inflammation"},{"key":"ref_281","doi-asserted-by":"crossref","first-page":"389","DOI":"10.2337\/db22-0553","article-title":"Isorhapontigenin Attenuates Cardiac Microvascular Injury in Diabetes via the Inhibition of Mitochondria-Associated Ferroptosis Through PRDX2-MFN2-ACSL4 Pathways","volume":"72","author":"Chen","year":"2023","journal-title":"Diabetes"},{"key":"ref_282","doi-asserted-by":"crossref","first-page":"1127931","DOI":"10.3389\/fphar.2023.1127931","article-title":"Kumatakenin Inhibited Iron-Ferroptosis in Epithelial Cells from Colitis Mice by Regulating the Eno3-IRP1-Axis","volume":"14","author":"Arenbaoligao","year":"2023","journal-title":"Front. Pharmacol."},{"key":"ref_283","doi-asserted-by":"crossref","first-page":"176031","DOI":"10.1016\/j.ejphar.2023.176031","article-title":"Licochalcone a Improves Cardiac Functions after Ischemia-Reperfusion via Reduction of Ferroptosis in Rats","volume":"957","author":"Lin","year":"2023","journal-title":"Eur. J. Pharmacol."},{"key":"ref_284","doi-asserted-by":"crossref","first-page":"3175","DOI":"10.1007\/s12035-023-03270-6","article-title":"Methyl Ferulic Acid Alleviates Neuropathic Pain by Inhibiting Nox4-Induced Ferroptosis in Dorsal Root Ganglia Neurons in Rats","volume":"60","author":"Liu","year":"2023","journal-title":"Mol. Neurobiol."},{"key":"ref_285","doi-asserted-by":"crossref","first-page":"153641","DOI":"10.1016\/j.phymed.2021.153641","article-title":"Identification of Prenylated Phenolics in Mulberry Leaf and Their Neuroprotective Activity","volume":"90","author":"Wen","year":"2021","journal-title":"Phytomedicine"},{"key":"ref_286","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1097\/SHK.0000000000002224","article-title":"Nobiletin Ameliorates Heatstroke-Induced Acute Lung Injury by Inhibiting Ferroptosis via P53\/SLC7A11 Pathway","volume":"61","author":"Chen","year":"2023","journal-title":"Shock"},{"key":"ref_287","doi-asserted-by":"crossref","unstructured":"Huang, Q., Tian, L., Zhang, Y., Qiu, Z., Lei, S., and Xia, Z.-Y. (2023). Nobiletin Alleviates Myocardial Ischemia-Reperfusion Injury via Ferroptosis in Rats with Type-2 Diabetes Mellitus. Biomed. Pharmacother., 163.","DOI":"10.1016\/j.biopha.2023.114795"},{"key":"ref_288","doi-asserted-by":"crossref","unstructured":"Lo, Y.-H., Yang, S.-F., Cheng, C.-C., Hsu, K.-C., Chen, Y.-S., Chen, Y.-Y., Wang, C.-W., Guan, S.-S., and Wu, C.-T. (2022). Nobiletin Alleviates Ferroptosis-Associated Renal Injury, Inflammation, and Fibrosis in a Unilateral Ureteral Obstruction Mouse Model. Biomedicines, 10.","DOI":"10.3390\/biomedicines10030595"},{"key":"ref_289","doi-asserted-by":"crossref","first-page":"16043","DOI":"10.1021\/acs.jafc.3c01497","article-title":"Phlorizin Mitigates Dextran Sulfate Sodium-Induced Colitis in Mice by Modulating Gut Microbiota and Inhibiting Ferroptosis","volume":"71","author":"Cheng","year":"2023","journal-title":"J. Agric. Food Chem."},{"key":"ref_290","doi-asserted-by":"crossref","first-page":"122162","DOI":"10.1016\/j.lfs.2023.122162","article-title":"Activation of the Nrf-2 Pathway by Pinocembrin Safeguards Vertebral Endplate Chondrocytes against Apoptosis and Degeneration Caused by Oxidative Stress","volume":"333","author":"Wang","year":"2023","journal-title":"Life Sci."},{"key":"ref_291","doi-asserted-by":"crossref","first-page":"9947191","DOI":"10.1155\/2022\/9947191","article-title":"Polydatin Attenuates Cisplatin-Induced Acute Kidney Injury by Inhibiting Ferroptosis","volume":"2022","author":"Zhou","year":"2022","journal-title":"Oxidative Med. Cell. Longev."},{"key":"ref_292","doi-asserted-by":"crossref","unstructured":"Chen, L., Huang, J., Yao, Z.-M., Sun, X.-R., Tong, X.-H., Hu, M., Zhang, Y., and Dong, S.-Y. (2023). Procyanidins Alleviated Cerebral Ischemia\/Reperfusion Injury by Inhibiting Ferroptosis via the Nrf2\/HO-1 Signaling Pathway. Molecules, 28.","DOI":"10.3390\/molecules28083582"},{"key":"ref_293","doi-asserted-by":"crossref","first-page":"121279","DOI":"10.1016\/j.lfs.2022.121279","article-title":"Proanthocyanidins Attenuates Ferroptosis against Influenza-Induced Acute Lung Injury in Mice by Reducing IFN-\u03b3","volume":"314","author":"Lv","year":"2023","journal-title":"Life Sci."},{"key":"ref_294","doi-asserted-by":"crossref","first-page":"101807","DOI":"10.1016\/j.jchemneu.2020.101807","article-title":"Proanthocyanidin Promotes Functional Recovery of Spinal Cord Injury via Inhibiting Ferroptosis","volume":"107","author":"Zhou","year":"2020","journal-title":"J. Chem. Neuroanat."},{"key":"ref_295","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1007\/s12035-016-9690-z","article-title":"Protocatechualdehyde Protects Against Cerebral Ischemia-Reperfusion-Induced Oxidative Injury Via Protein Kinase C\u03b5\/Nrf2\/HO-1 Pathway","volume":"54","author":"Guo","year":"2017","journal-title":"Mol. Neurobiol."},{"key":"ref_296","doi-asserted-by":"crossref","unstructured":"Yang, X., Sun, X., Zhou, F., Xiao, S., Zhong, L., Hu, S., Zhou, Z., Li, L., and Tan, Y. (2023). Protocatechuic Acid Alleviates Dextran-Sulfate-Sodium-Induced Ulcerative Colitis in Mice via the Regulation of Intestinal Flora and Ferroptosis. Molecules, 28.","DOI":"10.3390\/molecules28093775"},{"key":"ref_297","doi-asserted-by":"crossref","first-page":"8258354","DOI":"10.1155\/2023\/8258354","article-title":"Pterostilbene Confers Protection against Diquat-Induced Intestinal Damage with Potential Regulation of Redox Status and Ferroptosis in Broiler Chickens","volume":"2023","author":"Chen","year":"2023","journal-title":"Oxidative Med. Cell. Longev."},{"key":"ref_298","doi-asserted-by":"crossref","unstructured":"Chen, X., Song, Q.L., Li, Z.H., Ji, R., Wang, J.Y., Cao, M.L., Mu, X.F., Zhang, Y., Guo, D.Y., and Yang, J. (2023). Pterostilbene Ameliorates Oxidative Damage and Ferroptosis in Human Ovarian Granulosa Cells by Regulating the Nrf2\/HO-1 Pathway. Arch. Biochemy Biophys., 738.","DOI":"10.1016\/j.abb.2023.109561"},{"key":"ref_299","doi-asserted-by":"crossref","first-page":"e382523","DOI":"10.1590\/acb382523","article-title":"Puerarin Alleviated Oxidative Stress and Ferroptosis during Renal Fibrosis Induced by Ischemia\/Reperfusion Injury via TLR4\/Nox4 Pathway in Rats","volume":"38","author":"Jian","year":"2023","journal-title":"Acta Cir. Bras."},{"key":"ref_300","doi-asserted-by":"crossref","first-page":"3617","DOI":"10.18632\/aging.204033","article-title":"Puerarin Protects against Sepsis-Induced Myocardial Injury through AMPK-Mediated Ferroptosis Signaling","volume":"14","author":"Zhou","year":"2022","journal-title":"Aging"},{"key":"ref_301","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.bbrc.2018.02.061","article-title":"Puerarin Protects against Heart Failure Induced by Pressure Overload through Mitigation of Ferroptosis","volume":"497","author":"Liu","year":"2018","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"ref_302","doi-asserted-by":"crossref","first-page":"113717","DOI":"10.1016\/j.yexcr.2023.113717","article-title":"Punicalagin Attenuates TNF-\u03b1-Induced Oxidative Damage and Promotes Osteogenic Differentiation of Bone Mesenchymal Stem Cells by Activating the Nrf2\/HO-1 Pathway","volume":"430","author":"Huang","year":"2023","journal-title":"Exp. Cell Res."},{"key":"ref_303","doi-asserted-by":"crossref","first-page":"116","DOI":"10.3892\/ijmm.2023.5319","article-title":"Quercetin Ameliorates Ferroptosis of Rat Cardiomyocytes via Activation of the SIRT1\/P53\/SLC7A11 Signaling Pathway to Alleviate Sepsis-induced Cardiomyopathy","volume":"52","author":"Lin","year":"2023","journal-title":"Int. J. Mol. Med."},{"key":"ref_304","doi-asserted-by":"crossref","first-page":"175407","DOI":"10.1016\/j.ejphar.2022.175407","article-title":"Quercetin Alleviates Ferroptosis Accompanied by Reducing M1 Macrophage Polarization during Neutrophilic Airway Inflammation","volume":"938","author":"Wang","year":"2023","journal-title":"Eur. J. Pharmacol."},{"key":"ref_305","doi-asserted-by":"crossref","unstructured":"Wang, Y., Li, W., Wang, M., Chen, H., Li, Y., Wei, W., Liu, X., Wu, Y., Luo, S., and Liu, X. (2023). Quercetin Prevents the Ferroptosis of OPCs by Inhibiting the Id2\/Transferrin Pathway. Chem. Biol. Interact., 381.","DOI":"10.1016\/j.cbi.2023.110556"},{"key":"ref_306","doi-asserted-by":"crossref","first-page":"10761","DOI":"10.1021\/acs.jafc.3c02027","article-title":"Quercetin Alleviates Deoxynivalenol-Induced Intestinal Damage by Suppressing Inflammation and Ferroptosis in Mice","volume":"71","author":"Ye","year":"2023","journal-title":"J. Agric. Food Chem."},{"key":"ref_307","doi-asserted-by":"crossref","first-page":"113586","DOI":"10.1016\/j.fct.2022.113586","article-title":"Quercetin and Resveratrol Inhibit Ferroptosis Independently of Nrf2\u2013ARE Activation in Mouse Hippocampal HT22 Cells","volume":"172","author":"Kato","year":"2023","journal-title":"Food Chem. Toxicol."},{"key":"ref_308","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1530\/JME-22-0086","article-title":"Quercetin Protects Rat BMSCs from Oxidative Stress via Ferroptosis","volume":"69","author":"Lan","year":"2022","journal-title":"J. Mol. Endocrinol."},{"key":"ref_309","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.jare.2020.07.007","article-title":"Quercetin Alleviates Acute Kidney Injury by Inhibiting Ferroptosis","volume":"28","author":"Wang","year":"2021","journal-title":"J. Adv. Res."},{"key":"ref_310","doi-asserted-by":"crossref","unstructured":"Li, D., Jiang, C., Mei, G., Zhao, Y., Chen, L., Liu, J., Tang, Y., Gao, C., and Yao, P. (2020). Quercetin Alleviates Ferroptosis of Pancreatic \u03b2 Cells in Type 2 Diabetes. Nutrients, 12.","DOI":"10.3390\/nu12102954"},{"key":"ref_311","doi-asserted-by":"crossref","unstructured":"Li, D., Song, C., Zhang, J., and Zhao, X. (2023). Resveratrol Alleviated 5-FU-Induced Cardiotoxicity by Attenuating GPX4 Dependent Ferroptosis. J. Nutr. Biochem., 112.","DOI":"10.1016\/j.jnutbio.2022.109241"},{"key":"ref_312","doi-asserted-by":"crossref","first-page":"446","DOI":"10.55730\/1300-0144.5604","article-title":"Resveratrol Attenuated High Intensity Exercise Training-Induced Inflammation and Ferroptosis via Nrf2\/FTH1\/GPX4 Pathway in Intestine of Mice","volume":"53","author":"Xu","year":"2023","journal-title":"Turk. J. Med. Sci."},{"key":"ref_313","doi-asserted-by":"crossref","first-page":"3075","DOI":"10.1111\/jcmm.17874","article-title":"Resveratrol Inhibits Ferroptosis and Decelerates Heart Failure Progression via Sirt1\/P53 Pathway Activation","volume":"27","author":"Zhang","year":"2023","journal-title":"J. Cell. Mol. Med."},{"key":"ref_314","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1055\/a-1923-4399","article-title":"Resveratrol Protects BEAS-2B Cells against Erastin-Induced Ferroptosis through the Nrf2\/Keap1 Pathway","volume":"89","author":"Huang","year":"2023","journal-title":"Planta Med."},{"key":"ref_315","doi-asserted-by":"crossref","first-page":"153589","DOI":"10.1016\/j.tox.2023.153589","article-title":"Resveratrol Protects against Deoxynivalenol-Induced Ferroptosis in HepG2 Cells","volume":"494","author":"Wang","year":"2023","journal-title":"Toxicology"},{"key":"ref_316","doi-asserted-by":"crossref","first-page":"906073","DOI":"10.3389\/fphar.2022.906073","article-title":"Resveratrol Attenuate Myocardial Injury by Inhibiting Ferroptosis Via Inducing KAT5\/GPX4 in Myocardial Infarction","volume":"13","author":"Liu","year":"2022","journal-title":"Front. Pharmacol."},{"key":"ref_317","doi-asserted-by":"crossref","first-page":"E21","DOI":"10.1152\/ajpendo.00227.2021","article-title":"Resveratrol Mediates the miR-149\/HMGB1 Axis and Regulates the Ferroptosis Pathway to Protect Myocardium in Endotoxemia Mice","volume":"323","author":"Wang","year":"2022","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"ref_318","doi-asserted-by":"crossref","first-page":"2157521","DOI":"10.1080\/08941939.2022.2157521","article-title":"Resveratrol Attenuates Sepsis-Induced Cardiomyopathy in Rats through Anti-Ferroptosis via the Sirt1\/Nrf2 Pathway","volume":"36","author":"Zeng","year":"2023","journal-title":"J. Investig. Surg."},{"key":"ref_319","doi-asserted-by":"crossref","first-page":"153048","DOI":"10.1016\/j.tox.2021.153048","article-title":"Resveratrol Protected Acrolein-Induced Ferroptosis and Insulin Secretion Dysfunction via ER-Stress- Related PERK Pathway in MIN6 Cells","volume":"465","author":"Zhang","year":"2022","journal-title":"Toxicology"},{"key":"ref_320","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1002\/cbin.11960","article-title":"Protective Effect of Rutin on Ferroptosis-Induced Oxidative Stress in Aging Laying Hens through Nrf2\/HO-1 Signaling","volume":"47","author":"Wu","year":"2023","journal-title":"Cell Biol. Int."},{"key":"ref_321","doi-asserted-by":"crossref","first-page":"507","DOI":"10.3892\/etm.2023.12206","article-title":"Salidroside Inhibits Renal Ischemia\/Reperfusion Injury-induced Ferroptosis by the PI3K\/AKT Signaling Pathway","volume":"26","author":"Tang","year":"2023","journal-title":"Exp. Ther. Med."},{"key":"ref_322","doi-asserted-by":"crossref","unstructured":"Wang, Y., Han, J., Luo, L., Kasim, V., and Wu, S. (2023). Salidroside Facilitates Therapeutic Angiogenesis in Diabetic Hindlimb Ischemia by Inhibiting Ferroptosis. Biomed. Pharmacother., 159.","DOI":"10.1016\/j.biopha.2023.114245"},{"key":"ref_323","doi-asserted-by":"crossref","first-page":"109731","DOI":"10.1016\/j.intimp.2023.109731","article-title":"Salidroside Postconditioning Attenuates Ferroptosis-Mediated Lung Ischemia-Reperfusion Injury by Activating the Nrf2\/SLC7A11 Signaling Axis","volume":"115","author":"Wang","year":"2023","journal-title":"Int. Immunopharmacol."},{"key":"ref_324","doi-asserted-by":"crossref","first-page":"153964","DOI":"10.1016\/j.phymed.2022.153964","article-title":"Salidroside Inhibits Doxorubicin-Induced Cardiomyopathy by Modulating a Ferroptosis-Dependent Pathway","volume":"99","author":"Chen","year":"2022","journal-title":"Phytomedicine"},{"key":"ref_325","doi-asserted-by":"crossref","unstructured":"Yang, S., Pei, T., Wang, L., Zeng, Y., Li, W., Yan, S., Xiao, W., and Cheng, W. (2022). Salidroside Alleviates Renal Fibrosis in SAMP8 Mice by Inhibiting Ferroptosis. Molecules, 27.","DOI":"10.3390\/molecules27228039"},{"key":"ref_326","doi-asserted-by":"crossref","first-page":"115331","DOI":"10.1016\/j.jep.2022.115331","article-title":"Salvianolate Ameliorates Renal Tubular Injury through the Keap1\/Nrf2\/ARE Pathway in Mouse Kidney Ischemia-Reperfusion Injury","volume":"293","author":"Sun","year":"2022","journal-title":"J. Ethnopharmacol."},{"key":"ref_327","doi-asserted-by":"crossref","first-page":"168073","DOI":"10.1016\/j.scitotenv.2023.168073","article-title":"Salvianolic Acid A Attenuates Arsenic-Induced Ferroptosis and Kidney Injury via HIF-2\u03b1\/DUOX1\/GPX4 and Iron Homeostasis","volume":"907","author":"Yang","year":"2023","journal-title":"Sci. Total Environ."},{"key":"ref_328","doi-asserted-by":"crossref","unstructured":"Zhao, Y., Li, Q., Jian, W., Han, X., Zhang, Y., Zeng, Y., Liu, R., Wang, Q., and Song, Q. (2023). Protective Benefits of Salvianic Acid A against Retinal Iron Overload by Inhibition of Ferroptosis. Biomed. Pharmacother., 165.","DOI":"10.1016\/j.biopha.2023.115140"},{"key":"ref_329","doi-asserted-by":"crossref","unstructured":"Xu, X., Mao, C., Zhang, C., Zhang, M., Gong, J., and Wang, X. (2023). Salvianolic Acid B Inhibits Ferroptosis and Apoptosis during Myocardial Ischemia\/Reperfusion Injury via Decreasing the Ubiquitin-Proteasome Degradation of GPX4 and the ROS-JNK\/MAPK Pathways. Molecules, 28.","DOI":"10.3390\/molecules28104117"},{"key":"ref_330","doi-asserted-by":"crossref","first-page":"109257","DOI":"10.1016\/j.intimp.2022.109257","article-title":"Protective Effects of Salvianolic Acid B on Rat Ferroptosis in Myocardial Infarction through Upregulating the Nrf2 Signaling Pathway","volume":"112","author":"Shen","year":"2022","journal-title":"Int. Immunopharmacol."},{"key":"ref_331","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/j.freeradbiomed.2018.06.035","article-title":"Cerebroprotection by Salvianolic Acid B after Experimental Subarachnoid Hemorrhage Occurs via Nrf2- and SIRT1-Dependent Pathways","volume":"124","author":"Zhang","year":"2018","journal-title":"Free Radic. Biol. Med."},{"key":"ref_332","doi-asserted-by":"crossref","first-page":"4587","DOI":"10.1002\/ptr.7928","article-title":"Scutellarein Alleviates Chronic Obstructive Pulmonary Disease through Inhibition of Ferroptosis by Chelating Iron and Interacting with Arachidonate 15-Lipoxygenase","volume":"37","author":"Liu","year":"2023","journal-title":"Phytother. Res."},{"key":"ref_333","doi-asserted-by":"crossref","first-page":"12671","DOI":"10.1039\/D1FO02913D","article-title":"Sesamin Attenuates PM2.5-Induced Cardiovascular Injury by Inhibiting Ferroptosis in Rats","volume":"12","author":"Ren","year":"2021","journal-title":"Food Funct."},{"key":"ref_334","doi-asserted-by":"crossref","unstructured":"Du, Q., Wu, X., Ma, K., Liu, W., Liu, P., Hayashi, T., Mizuno, K., Hattori, S., Fujisaki, H., and Ikejima, T. (2023). Silibinin Alleviates Ferroptosis of Rat Islet \u03b2 Cell INS-1 Induced by the Treatment with Palmitic Acid and High Glucose through Enhancing PINK1\/Parkin-Mediated Mitophagy. Arch. Biochem. Biophys., 743.","DOI":"10.1016\/j.abb.2023.109644"},{"key":"ref_335","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/s12012-023-09804-7","article-title":"Suberosin Alleviates Thiazolidinedione-Induced Cardiomyopathy in Diabetic Rats by Inhibiting Ferroptosis via Modulation of ACSL4-LPCAT3 and PI3K-AKT Signaling Pathways","volume":"23","author":"Iqbal","year":"2023","journal-title":"Cardiovasc. Toxicol."},{"key":"ref_336","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1111\/cbdd.14326","article-title":"Syringic Acid Suppresses Ferroptosis of Skeletal Muscle Cells to Alleviate Lower Limb Ischemia\/Reperfusion Injury in Mice via the HMGB1 Pathway","volume":"102","author":"Wang","year":"2023","journal-title":"Chem. Biol. Drug Des."},{"key":"ref_337","doi-asserted-by":"crossref","first-page":"12574","DOI":"10.1021\/acs.jafc.3c02934","article-title":"Tannic Acid Ameliorates Systemic Glucose and Lipid Metabolic Impairment Induced by Low-Dose T-2 Toxin Exposure","volume":"71","author":"Wang","year":"2023","journal-title":"J. Agric. Food Chem."},{"key":"ref_338","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1093\/toxres\/tfad038","article-title":"Tectorigenin Relieved Sepsis-Induced Myocardial Ferroptosis by Inhibiting the Expression of Smad3","volume":"12","author":"Fang","year":"2023","journal-title":"Toxicol. Res."},{"key":"ref_339","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1002\/ptr.7353","article-title":"Tectorigenin Protects against Unilateral Ureteral Obstruction by Inhibiting Smad3-Mediated Ferroptosis and Fibrosis","volume":"36","author":"Li","year":"2022","journal-title":"Phytother. Res."},{"key":"ref_340","doi-asserted-by":"crossref","first-page":"3531995","DOI":"10.1155\/2022\/3531995","article-title":"Theaflavin-3,3\u2032-Digallate Inhibits Erastin-Induced Chondrocytes Ferroptosis via the Nrf2\/GPX4 Signaling Pathway in Osteoarthritis","volume":"2022","author":"Xu","year":"2022","journal-title":"Oxidative Med. Cell. Longev."},{"key":"ref_341","doi-asserted-by":"crossref","first-page":"913367","DOI":"10.3389\/fphar.2022.913367","article-title":"Trilobatin, a Naturally Occurring Food Additive, Ameliorates Exhaustive Exercise-Induced Fatigue in Mice: Involvement of Nrf2\/ARE\/Ferroptosis Signaling Pathway","volume":"13","author":"Xiao","year":"2022","journal-title":"Front. Pharmacol."},{"key":"ref_342","doi-asserted-by":"crossref","first-page":"112892","DOI":"10.1016\/j.fct.2022.112892","article-title":"Umbelliferone Delays the Progression of Diabetic Nephropathy by Inhibiting Ferroptosis through Activation of the Nrf-2\/HO-1 Pathway","volume":"163","author":"Jin","year":"2022","journal-title":"Food Chem. Toxicol."},{"key":"ref_343","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1186\/s10020-023-00735-1","article-title":"Vitexin Attenuates Chronic Kidney Disease by Inhibiting Renal Tubular Epithelial Cell Ferroptosis via NRF2 Activation","volume":"29","author":"Song","year":"2023","journal-title":"Mol. Med."},{"key":"ref_344","doi-asserted-by":"crossref","first-page":"175787","DOI":"10.1016\/j.ejphar.2023.175787","article-title":"Vitexin Ameliorated Diabetic Nephropathy via Suppressing GPX4-Mediated Ferroptosis","volume":"951","author":"Zhang","year":"2023","journal-title":"Eur. J. Pharmacol."},{"key":"ref_345","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.freeradbiomed.2021.07.009","article-title":"Wedelolactone Alleviates Acute Pancreatitis and Associated Lung Injury via GPX4 Mediated Suppression of Pyroptosis and Ferroptosis","volume":"173","author":"Fan","year":"2021","journal-title":"Free Radic. Biol. Med."},{"key":"ref_346","doi-asserted-by":"crossref","unstructured":"Di Lorenzo, C., Colombo, F., Biella, S., Stockley, C., and Restani, P. (2021). Polyphenols and Human Health: The Role of Bioavailability. Nutrients, 13.","DOI":"10.3390\/nu13010273"},{"key":"ref_347","doi-asserted-by":"crossref","unstructured":"Bertelli, A., Biagi, M., Corsini, M., Baini, G., Cappellucci, G., and Miraldi, E. (2021). Polyphenols: From Theory to Practice. Foods, 10.","DOI":"10.3390\/foods10112595"},{"key":"ref_348","unstructured":"Grumezescu, A.M. (2016). Encapsulations, Academic Press. Nanotechnology in the Agri-Food Industry."},{"key":"ref_349","doi-asserted-by":"crossref","unstructured":"Lesjak, M., and Srai, K.S.S. (2019). Role of Dietary Flavonoids in Iron Homeostasis. Pharmaceuticals, 12.","DOI":"10.3390\/ph12030119"},{"key":"ref_350","doi-asserted-by":"crossref","unstructured":"Duda-Chodak, A., and Tarko, T. (2023). Possible Side Effects of Polyphenols and Their Interactions with Medicines. Molecules, 28.","DOI":"10.3390\/molecules28062536"},{"key":"ref_351","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1021\/acschembio.1c00953","article-title":"Machine Learning Classifies Ferroptosis and Apoptosis Cell Death Modalities with TfR1 Immunostaining","volume":"17","author":"Jin","year":"2022","journal-title":"ACS Chem. Biol."},{"key":"ref_352","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41420-023-01559-y","article-title":"CellDeathPred: A Deep Learning Framework for Ferroptosis and Apoptosis Prediction Based on Cell Painting","volume":"9","author":"Schorpp","year":"2023","journal-title":"Cell Death Discov."},{"key":"ref_353","doi-asserted-by":"crossref","unstructured":"Luo, L., Chen, X., and Huang, F. (2023). Machine Learning Revealed Ferroptosis Features and Ferroptosis-Related Gene-Based Immune Microenvironment in Lung Adenocarcinoma. Chem. Biol. Interact., 378.","DOI":"10.1016\/j.cbi.2023.110471"}],"container-title":["Antioxidants"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-3921\/13\/3\/334\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T14:11:30Z","timestamp":1760105490000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-3921\/13\/3\/334"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,10]]},"references-count":353,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2024,3]]}},"alternative-id":["antiox13030334"],"URL":"https:\/\/doi.org\/10.3390\/antiox13030334","relation":{},"ISSN":["2076-3921"],"issn-type":[{"value":"2076-3921","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,10]]}}}