{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T03:25:01Z","timestamp":1791084301298,"version":"4.1.0"},"reference-count":139,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2024,11,29]],"date-time":"2024-11-29T00:00:00Z","timestamp":1732838400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Mexican National Council of Humanities, Sciences, and Technology","award":["CB-A1-S-32913"],"award-info":[{"award-number":["CB-A1-S-32913"]}]},{"name":"Mexican National Council of Humanities, Sciences, and Technology","award":["CF-2023-G-726"],"award-info":[{"award-number":["CF-2023-G-726"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antioxidants"],"abstract":"<jats:p>The \u201cOne Health approach\u201d has evidenced the significant impact of xenobiotic exposure to health, and humans are a relevant target for their toxic effects. Bisphenol A (BPA) exerts a ubiquitous exposure source in all ecosystems. Given its endocrine-disrupting and harmful consequences on health, several countries have enforced new regulations to reduce exposure to BPA. Cardiovascular diseases (CVDs) are complex conditions that lead to higher mortality worldwide, where family history, lifestyle, and environmental factors, like BPA exposure, have a remarkable contribution. This chemical compound is the most widely used in plastic and epoxy resin manufacturing and has been associated with effects on human health. Therefore, new-generation bisphenols (NGBs) are replacing BPA use, arguing that they do not harm health. Nonetheless, the knowledge about whether NGBs are secure options is scanty. Although BPA\u2019s effects on several organs and systems have been documented, the role of BPA and NGBs in CVDs has yet to be explored. This review\u2019s goals are focused on the processes of endothelial activation (EA)\u2013endothelial dysfunction (ED), a cornerstone of CVDs development, bisphenols\u2019 (BPs) effects on these processes through oxidant and antioxidant system alteration. Despite the scarce evidence on pro-oxidant effects associated with NGBs, our review demonstrated a comparable harmful effect on BPA. The results from the present review suggest that the biological mechanisms to explain BPs cardiotoxic effects are the oxidant stress \u2194\u00a0inflammatory response\u00a0\u2194\u00a0EA\u00a0\u2194\u00a0ED\u00a0\u2192\u00a0atherosclerotic plate\u00a0\u2192 coagulation promotion. Other effects contributing to CVD development include altered lipid metabolism, ionic channels, and the activation of different intracellular pathways, which contribute to ED perpetuation in a concerted manner.<\/jats:p>","DOI":"10.3390\/antiox13121468","type":"journal-article","created":{"date-parts":[[2024,11,29]],"date-time":"2024-11-29T05:02:22Z","timestamp":1732856542000},"page":"1468","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Bisphenol A and Its Emergent Substitutes: State of the Art of the Impact of These Plasticizers on Oxidative Stress and Its Role in Vascular Dysfunction"],"prefix":"10.3390","volume":"13","author":[{"given":"Jos\u00e9 R.","family":"Palacios-Valladares","sequence":"first","affiliation":[{"name":"Department of Toxicology, Center for Research and Advanced Studies of the National Polytechnic Institute, Mexico City 07360, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yesenia I.","family":"Martinez-Jimenez","sequence":"additional","affiliation":[{"name":"Department of Toxicology, Center for Research and Advanced Studies of the National Polytechnic Institute, Mexico City 07360, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa","family":"Morillon-Torres","sequence":"additional","affiliation":[{"name":"Department of Toxicology, Center for Research and Advanced Studies of the National Polytechnic Institute, Mexico City 07360, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar B.","family":"Rivera-Maya","sequence":"additional","affiliation":[{"name":"Department of Toxicology, Center for Research and Advanced Studies of the National Polytechnic Institute, Mexico City 07360, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9653-7501","authenticated-orcid":false,"given":"Rocio","family":"G\u00f3mez","sequence":"additional","affiliation":[{"name":"Department of Toxicology, Center for Research and Advanced Studies of the National Polytechnic Institute, Mexico City 07360, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8284-2217","authenticated-orcid":false,"given":"Emma S.","family":"Calderon-Aranda","sequence":"additional","affiliation":[{"name":"Department of Toxicology, Center for Research and Advanced Studies of the National Polytechnic Institute, Mexico City 07360, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,11,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Chareonrungrueangchai, K., Wongkawinwoot, K., Anothaisintawee, T., and Reutrakul, S. (2020). Dietary Factors and Risks of Cardiovascular Diseases: An umbrella review. Nutrients, 12.","DOI":"10.3390\/nu12041088"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Roerecke, M. (2021). Alcohol\u2019s Impact on the Cardiovascular System. Nutrients, 13.","DOI":"10.3390\/nu13103419"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1136\/bmj.298.6676.789","article-title":"Meta-Analysis of Relation between Cigarette Smoking and Stroke","volume":"298","author":"Shinton","year":"1989","journal-title":"Br. Med. J."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1161\/CIRCRESAHA.118.312669","article-title":"Sedentary Behavior, Exercise, and Cardiovascular Health","volume":"124","author":"Lavie","year":"2019","journal-title":"Circ. Res."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"k4247","DOI":"10.1136\/bmj.k4247","article-title":"Sex Differences in Risk Factors for Myocardial Infarction: Cohort Study of UK Biobank Participants","volume":"363","author":"Millett","year":"2018","journal-title":"BMJ"},{"key":"ref_6","first-page":"2","article-title":"Ethnic Minorities and Coronary Heart Disease: An Update and Future Directions","volume":"18","author":"Alvarez","year":"2016","journal-title":"Curr. Atheroscler. Rep."},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Meraz-R\u00edos, M.A., Majluf-Cru-z, A., Santana, C., Noris, G., Camacho-Mejorado, R., Acosta-Saavedra, L.C., Calder\u00f3n-Aranda, E.S., Hern\u00e1ndez-Ju\u00e1rez, J., Maga\u00f1a, J.J., and G\u00f3mez, R. (2014). Association of VWA and TPOX Polymorphisms with Venous Thrombosis in Mexican Mestizos. BioMed Res. Int., 2014.","DOI":"10.1155\/2014\/697689"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"e027684","DOI":"10.1161\/JAHA.122.027684","article-title":"Age-Dependent Association Between Modifiable Risk Factors and Incident Cardiovascular Disease","volume":"12","author":"Kaneko","year":"2023","journal-title":"J. Am. Heart Assoc."},{"key":"ref_9","first-page":"14","article-title":"Environmental Toxic Metal Contaminants and Risk of Cardiovascular Disease: Systematic Review and Meta-Analysis","volume":"362","author":"Chowdhury","year":"2018","journal-title":"BMJ"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"109464","DOI":"10.1016\/j.envres.2020.109464","article-title":"The Association between Environmental Endocrine Disruptors and Cardiovascular Diseases: A Systematic Review and Meta-Analysis","volume":"187","author":"Fu","year":"2020","journal-title":"Environ. Res."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"9876","DOI":"10.1021\/acs.est.9b02963","article-title":"Bisphenol A, Chlorinated Derivatives of Bisphenol A and Occurrence of Myocardial Infarction in Patients with Type 2 Diabetes: Nested Case-Control Studies in Two European Cohorts","volume":"53","author":"Hu","year":"2019","journal-title":"Environ. Sci. Technol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1146\/annurev.pathol.4.110807.092155","article-title":"Mechanisms of Endothelial Dysfunction, Injury, and Death","volume":"4","author":"Pober","year":"2009","journal-title":"Annu. Rev. Pathol. Mech. Dis."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1161\/CIRCRESAHA.115.306301","article-title":"Endothelial Cell Dysfunction and the Pathobiology of Atherosclerosis","volume":"118","author":"Gimbrone","year":"2016","journal-title":"Circ. Res."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1083\/jcb.201412052","article-title":"Recent Insights into the Cellular Biology of Atherosclerosis","volume":"209","author":"Tabas","year":"2015","journal-title":"J. Cell Biol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1056\/NEJMra043430","article-title":"Inflammation, Atherosclerosis, and Coronary Artery Disease","volume":"352","author":"Hansson","year":"2005","journal-title":"N. Engl. J. Med."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.1093\/eurheartj\/ehv044","article-title":"TLR2 and Neutrophils Potentiate Endothelial Stress, Apoptosis and Detachment: Implications for Superficial Erosion","volume":"36","author":"Quillard","year":"2015","journal-title":"Eur. Heart J."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1016\/S0735-1097(03)00994-X","article-title":"The Clinical Implications of Endothelial Dysfunction","volume":"42","author":"Widlansky","year":"2003","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1080\/10408347.2019.1626698","article-title":"Application of Molecularly Imprinted Polymers for Bisphenols Extraction from Food Samples\u2013A Review","volume":"50","author":"Kubiak","year":"2020","journal-title":"Crit. Rev. Anal. Chem."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"137952","DOI":"10.1016\/j.scitotenv.2020.137952","article-title":"Cardiovascular Toxicity and Mechanism of Bisphenol A and Emerging Risk of Bisphenol S","volume":"723","author":"Zhang","year":"2020","journal-title":"Sci. Total Environ."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"142941","DOI":"10.1016\/j.scitotenv.2020.142941","article-title":"Effects of Bisphenol A on Cardiovascular Disease: An Epidemiological Study Using National Health and Nutrition Examination Survey 2003\u20132016 and Meta-Analysis","volume":"763","author":"Moon","year":"2020","journal-title":"Sci. Total Environ."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1080\/10408444.2022.2142514","article-title":"Effects of BPA Substitutes on the Prenatal and Cardiovascular Systems","volume":"52","author":"Lorigo","year":"2022","journal-title":"Crit. Rev. Toxicol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"106031","DOI":"10.1016\/j.envint.2020.106031","article-title":"Pharmacokinetics of Bisphenol A in Humans Following Dermal Administration","volume":"144","author":"Sasso","year":"2020","journal-title":"Environ. Int."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1080\/152873901753170740","article-title":"Bioavailability and Mammary Excretion of Bisphenol a in Sprague-Dawley Rats","volume":"64","author":"Yoo","year":"2001","journal-title":"J. Toxicol. Environ. Health Part A"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.envpol.2017.06.026","article-title":"Worldwide Human Daily Intakes of Bisphenol A (BPA) Estimated from Global Urinary Concentration Data (2000\u20132016) and Its Risk Analysis","volume":"230","author":"Huang","year":"2017","journal-title":"Environ. Pollut."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1016\/j.envres.2016.03.024","article-title":"Risk Assessment Based on Urinary Bisphenol A Levels in the General Korean Population","volume":"150","author":"Park","year":"2016","journal-title":"Environ. Res."},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Lauretta, R., Sansone, A., Sansone, M., Romanelli, F., and Appetecchia, M. (2019). Endocrine Disrupting Chemicals: Effects on Endocrine Glands. Front. Endocrinol., 10.","DOI":"10.3389\/fendo.2019.00178"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1038\/nrcardio.2015.152","article-title":"Environmental Factors in Cardiovascular Disease","volume":"12","author":"Cosselman","year":"2015","journal-title":"Nat. Rev. Cardiol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"110300","DOI":"10.1016\/j.ecoenv.2020.110300","article-title":"Relationship between Urinary Bisphenol a Levels and Cardiovascular Diseases in the U.S. Adult Population, 2003\u20132014","volume":"192","author":"Cai","year":"2020","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"120106","DOI":"10.1016\/j.envpol.2022.120106","article-title":"Relationship between Emergent BPA-Substitutes and Renal and Cardiovascular Diseases in Adult Population","volume":"313","year":"2022","journal-title":"Environ. Pollut."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.atherosclerosis.2011.05.001","article-title":"Circulating Levels of Bisphenol A and Phthalates Are Related to Carotid Atherosclerosis in the Elderly","volume":"218","author":"Lind","year":"2011","journal-title":"Atherosclerosis"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.scitotenv.2011.11.064","article-title":"Circulating Levels of Metals Are Related to Carotid Atherosclerosis in Elderly","volume":"416","author":"Lind","year":"2012","journal-title":"Sci. Total Environ."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"114845","DOI":"10.1016\/j.taap.2019.114845","article-title":"Toxicokinetics of Bisphenol S in Rats for Predicting Human Bisphenol S Clearance from Allometric Scaling","volume":"386","author":"Gayrard","year":"2020","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"ref_33","doi-asserted-by":"crossref","unstructured":"Zhu, Z., Long, X., Wang, J., Cao, Q., Yang, H., and Zhang, Y. (2023). Bisphenol A Has a Sex-Dependent Disruptive Effect on Hepatic Lipid Metabolism in Zebrafish. Comp. Biochem. Physiol. Part C Toxicol. Pharmacol., 268.","DOI":"10.1016\/j.cbpc.2023.109616"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"e000492","DOI":"10.1161\/JAHA.113.000492","article-title":"Bisphenol A Increases Atherosclerosis in Pregnane X Receptor-Humanized ApoE Deficient Mice","volume":"3","author":"Sui","year":"2014","journal-title":"J. Am. Heart Assoc."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"200167","DOI":"10.1098\/rsos.200167","article-title":"Correction to \u2018ALOX5, LPA, MMP9 and TPO Gene Polymorphisms Increase Atherothrombosis Susceptibility in Middle-Aged Mexicans\u2019","volume":"7","author":"Noris","year":"2020","journal-title":"R. Soc. Open Sci."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.tox.2014.08.006","article-title":"Adverse Effects of Long-Term Exposure to Bisphenol A during Adulthood Leading to Hyperglycaemia and Hypercholesterolemia in Mice","volume":"325","author":"Marmugi","year":"2014","journal-title":"Toxicology"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"122211","DOI":"10.1016\/j.envpol.2023.122211","article-title":"G Protein-Coupled Estrogen Receptor Activation by Bisphenol-A Disrupts Lipid Metabolism and Induces Ferroptosis in the Liver","volume":"334","author":"He","year":"2023","journal-title":"Environ. Pollut."},{"key":"ref_38","doi-asserted-by":"crossref","unstructured":"Hong, L., Xu, Y., Wang, D., Zhang, Q., Li, X., Xie, C., Wu, J., Zhong, C., Fu, J., and Geng, S. (2023). Sulforaphane Ameliorates Bisphenol A-Induced Hepatic Lipid Accumulation by Inhibiting Endoplasmic Reticulum Stress. Sci. Rep., 13.","DOI":"10.1038\/s41598-023-28395-5"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"113041","DOI":"10.1016\/j.ecoenv.2021.113041","article-title":"Bisphenol A Disrupts Apolipoprotein E Expression through Estrogen-Related Receptor Gamma and DNA Methlylation in the Liver of Male Rare Minnow Gobiocypris Rarus","volume":"228","author":"Zhang","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"105999","DOI":"10.1016\/j.aquatox.2021.105999","article-title":"Bisphenol A Regulates Apolipoprotein A1 Expression through Estrogen Receptors and DNA Methlylation and Leads to Cholesterol Disorder in Rare Minnow Testis","volume":"241","author":"Zhang","year":"2021","journal-title":"Aquat. Toxicol."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1002\/tox.22889","article-title":"Bisphenols B, E, F, and S and 4-Cumylphenol Induce Lipid Accumulation in Mouse Adipocytes Similarly to Bisphenol A","volume":"35","author":"Svingen","year":"2020","journal-title":"Environ. Toxicol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"111298","DOI":"10.1016\/j.fct.2020.111298","article-title":"Bisphenol A Analogues (BPS and BPF) Present a Greater Obesogenic Capacity in 3T3-L1 Cell Line","volume":"140","author":"Blanco","year":"2020","journal-title":"Food Chem. Toxicol."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"108331","DOI":"10.1016\/j.envint.2023.108331","article-title":"Bisphenol S Remodels Red Blood Cell Membrane Lipids by Altering Plasma Lipid Levels, Causing the Risk of Venous Thrombosis in SD Rats and Zebrafish Embryos","volume":"182","author":"Li","year":"2023","journal-title":"Environ. Int."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"C63","DOI":"10.1152\/ajpcell.00175.2019","article-title":"Bisphenol AF Promotes Inflammation in Human White Adipocytes","volume":"318","author":"Chernis","year":"2019","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1111\/j.1474-9726.2010.00557.x","article-title":"Short-term calorie restriction reverses vascular endothelial dysfunction in old mice by increasing nitric oxide and reducing oxidative stress","volume":"9","author":"Rippe","year":"2010","journal-title":"Aging Cell"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.ccc.2018.11.014","article-title":"Therapeutic Opportunities for Hepcidin in Acute Care Medicine","volume":"35","author":"Chawla","year":"2019","journal-title":"Crit. Care Clin."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1161\/01.HYP.37.2.529","article-title":"Superoxide Excess in Hypertension and Aging a Common Cause of Endothelial Dysfunction","volume":"37","author":"Hamilton","year":"2001","journal-title":"Hypertension"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1161\/01.HYP.28.3.488","article-title":"Nitrotyrosine Residues in Placenta","volume":"28","author":"Myatt","year":"1996","journal-title":"Hypertension"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1093\/gerona\/glr092","article-title":"Age-Associated Vascular Oxidative Stress, Nrf2 Dysfunction, and NF-KB Activation in the Nonhuman Primate Macaca Mulatta","volume":"66","author":"Ungvari","year":"2011","journal-title":"J. Gerontol. Ser. A Biol. Sci. Med. Sci."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"H1417","DOI":"10.1152\/ajpheart.00089.2013","article-title":"Role of Mitochondrial Oxidative Stress in Hypertension","volume":"305","author":"Dikalov","year":"2013","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1161\/01.RES.87.10.840","article-title":"Endothelial Dysfunction in Cardiovascular Diseases: The Role of Oxidant Stress","volume":"87","author":"Cai","year":"2000","journal-title":"Circ. Res."},{"key":"ref_52","doi-asserted-by":"crossref","unstructured":"Ponnuswamy, P., Schr\u00f6ttle, A., Ostermeier, E., Gr\u00fcner, S., Huang, P.L., Ertl, G., Hoffmann, U., Nieswandt, B., and Kuhlencordt, P.J. (2012). eNOS Protects from Atherosclerosis despite Relevant Superoxide Production by the Enzyme in apoE-\/- Mice. PLoS ONE, 7.","DOI":"10.1371\/journal.pone.0030193"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"H2227","DOI":"10.1152\/ajpheart.00325.2009","article-title":"Abnormal Nitric Oxide Production in Aged Rat Mesenteric Arteries Is Mediated by NAD(P)H Oxidase-Derived Peroxide","volume":"297","author":"Zhou","year":"2009","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1111\/omi.12252","article-title":"The roles of NADPH oxidase in modulating neutrophil effector responses. Molecular oral microbiology","volume":"34","author":"Zeng","year":"2020","journal-title":"Mol. Oral Microbiol."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11010-019-03667-9","article-title":"ROS and Diseases: Role in Metabolism and Energy Supply","volume":"467","author":"Yang","year":"2020","journal-title":"Mol. Cell. Biochem."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1152\/physrev.00026.2013","article-title":"Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release","volume":"94","author":"Zorov","year":"2014","journal-title":"Physiol. Rev."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1042\/CS20080196","article-title":"Role of TNF-\u03b1 in Vascular Dysfunction","volume":"116","author":"Zhang","year":"2009","journal-title":"Clin. Sci."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1165\/ajrcmb.24.6.4228","article-title":"Rapid Reactive Oxygen Species Production by Mitochondria in Endothelial Cells Exposed to Tumor Necrosis Factor-Is Mediated by Ceramide","volume":"24","author":"Corda","year":"2001","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1161\/01.ATV.20.4.1116","article-title":"Upregulation of Endothelial Receptor for Oxidized LDL (LOX-1) by Oxidized LDL and Implications in Apoptosis of Human Coronary Artery Endothelial Cells Evidence From Use of Antisense LOX-1 MRNA and Chemical Inhibitors","volume":"20","author":"Li","year":"2000","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"2932","DOI":"10.1002\/jnr.21739","article-title":"Signaling Pathways of Bisphenol A-Induced Apoptosis in Hippocampal Neuronal Cells: Role of Calcium-Induced Reactive Oxygen Species, Mitogen-Activated Protein Kinases, and Nuclear Factor-\u039aB","volume":"86","author":"Lee","year":"2008","journal-title":"J. Neurosci. Res."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1007\/s10753-014-9971-5","article-title":"MAPK and NF-\u039aB Pathways Are Involved in Bisphenol A-Induced TNF-\u03b1 and IL-6 Production in BV2 Microglial Cells","volume":"38","author":"Zhu","year":"2015","journal-title":"Inflammation"},{"key":"ref_62","doi-asserted-by":"crossref","unstructured":"Lu, S., Liu, M., Liu, H., Yang, C., Zhu, J., Ling, Y., and Kuang, H. (2024). Gestational Exposure to Bisphenol AF Causes Endocrine Disorder of Corpus Luteum by Altering Ovarian SIRT-1\/Nrf2\/NF-KB Expressions and Macrophage Proangiogenic Function in Mice. Biochem. Pharmacol., 220.","DOI":"10.1016\/j.bcp.2023.115954"},{"key":"ref_63","doi-asserted-by":"crossref","unstructured":"Odetayo, A.F., Adeyemi, W.J., and Olayaki, L.A. (2023). Omega-3 Fatty Acid Ameliorates Bisphenol F-Induced Testicular Toxicity by Modulating Nrf2\/NFkB Pathway and Apoptotic Signaling. Front. Endocrinol., 14.","DOI":"10.3389\/fendo.2023.1256154"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"116051","DOI":"10.1016\/j.envpol.2020.116051","article-title":"Bisphenol AF Induces Apoptosis via Estrogen Receptor Beta (ER\u03b2) and ROS-ASK1-JNK MAPK Pathway in Human Granulosa Cell Line KGN","volume":"270","author":"Huang","year":"2021","journal-title":"Environ. Pollut."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"122549","DOI":"10.1016\/j.jhazmat.2020.122549","article-title":"Mechanism Investigation on Bisphenol S-Induced Oxidative Stress and Inflammation in Murine RAW264.7 Cells: The Role of NLRP3 Inflammasome, TLR4, Nrf2 and MAPK","volume":"394","author":"Xie","year":"2020","journal-title":"J. Hazard. Mater."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/s12640-012-9353-4","article-title":"Neurotoxic Effects of Bisphenol AF on Calcium-Induced ROS and MAPKs","volume":"23","author":"Lee","year":"2013","journal-title":"Neurotox. Res."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"111299","DOI":"10.1016\/j.ecoenv.2020.111299","article-title":"Bisphenol A(BPA), BPS and BPB-Induced Oxidative Stress and Apoptosis Mediated by Mitochondria in Human Neuroblastoma Cell Lines","volume":"207","author":"Wang","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1177\/0748233719831528","article-title":"Bisphenol A Analogues Bisphenol B, Bisphenol F, and Bisphenol S Induce Oxidative Stress, Disrupt Daily Sperm Production, and Damage DNA in Rat Spermatozoa: A Comparative in Vitro and in Vivo Study","volume":"35","author":"Ullah","year":"2019","journal-title":"Toxicol. Ind. Health"},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"4719","DOI":"10.1096\/fj.14-252460","article-title":"Oral Administration of Bisphenol A Induces High Blood Pressure through Angiotensin II\/CaMKII-Dependent Uncoupling of ENOS","volume":"28","author":"Saura","year":"2014","journal-title":"FASEB J."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1172\/JCI200314172","article-title":"Oxidation of Tetrahydrobiopterin Leads to Uncoupling of Endothelial Cell Nitric Oxide Synthase in Hypertension","volume":"111","author":"Landmesser","year":"2003","journal-title":"J. Clin. Investig."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"123600","DOI":"10.1016\/j.envpol.2024.123600","article-title":"Bisphenols and Brominated Bisphenols Induced Endothelial Dysfunction via Its Disruption of Endothelial Nitric Oxide Synthase","volume":"346","author":"Hu","year":"2024","journal-title":"Environ. Pollut."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1007\/s00204-011-0766-2","article-title":"Proangiogenic Effects of Environmentally Relevant Levels of Bisphenol a in Human Primary Endothelial Cells","volume":"86","author":"Andersson","year":"2012","journal-title":"Arch. Toxicol."},{"key":"ref_73","doi-asserted-by":"crossref","unstructured":"Magnifico, M.C., Xhani, M., Sprovera, B., Buttari, B., Abballe, G., Desideri, F., Panieri, E., Saso, L., and Arese, M. (2022). Nitro-Oxidative Stress and Mitochondrial Dysfunction in Human Cell Lines Exposed to the Environmental Contaminants PFOA and BPA. Front. Biosci., 27.","DOI":"10.31083\/j.fbl2710292"},{"key":"ref_74","doi-asserted-by":"crossref","unstructured":"Wang, F., Ma, X., Sun, Q., Zhang, Y., Liu, Y., Gu, J., and Wang, L. (2023). Bisphenol B Induces Developmental Toxicity in Zebrafish via Oxidative Stress. Environ. Sci. Pollut. Res., 1\u20132.","DOI":"10.1007\/s11356-023-31161-9"},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.tiv.2017.02.018","article-title":"Bisphenol A, Bisphenol S, Bisphenol F and Bisphenol AF Induce Different Oxidative Stress and Damage in Human Red Blood Cells (in Vitro Study)","volume":"41","author":"Cyrkler","year":"2017","journal-title":"Toxicol. Vitr."},{"key":"ref_76","doi-asserted-by":"crossref","unstructured":"Xia, T., Guo, J., Zhang, B., Song, C., Zhao, Q., Cui, B., and Liu, Y. (2022). Bisphenol A Promotes the Progression of Colon Cancer Through Dual-Targeting of NADPH Oxidase and Mitochondrial Electron-Transport Chain to Produce ROS and Activating HIF-1\u03b1\/VEGF\/PI3K\/AKT Axis. Front. Endocrinol., 13.","DOI":"10.3389\/fendo.2022.933051"},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"114667","DOI":"10.1016\/j.fct.2024.114667","article-title":"SWATH-MS Reveals That Bisphenol A and Its Analogs Regulate Pathways Leading to Disruption in Insulin Signaling and Fatty Acid Metabolism","volume":"188","author":"Kulsange","year":"2024","journal-title":"Food Chem. Toxicol."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"2566","DOI":"10.1021\/acs.jafc.2c07236","article-title":"New Insights into How Melatonin Ameliorates Bisphenol A-Induced Colon Damage: Inhibition of NADPH Oxidase","volume":"71","author":"Yao","year":"2023","journal-title":"J. Agric. Food Chem."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"107603","DOI":"10.1016\/j.envint.2022.107603","article-title":"Exploring Oxidative Stress and Endothelial Dysfunction as a Mechanism Linking Bisphenol S Exposure to Vascular Disease in Human Umbilical Vein Endothelial Cells and a Mouse Model of Postnatal Exposure","volume":"170","author":"Easson","year":"2022","journal-title":"Environ. Int."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"15093","DOI":"10.1007\/s11356-020-08048-0","article-title":"Protective Effects of Quercetin against Oxidative Stress Induced by Bisphenol-A in Rat Cardiac Mitochondria","volume":"27","author":"Vanani","year":"2020","journal-title":"Environ. Sci. Pollut. Res."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1080\/01480545.2018.1504958","article-title":"Protective Effect of Naringin against BPA-Induced Cardiotoxicity through Prevention of Oxidative Stress in Male Wistar Rats","volume":"43","author":"Khodayar","year":"2020","journal-title":"Drug Chem. Toxicol."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1083\/jcb.200609074","article-title":"The Qo Site of the Mitochondrial Complex III Is Required for the Transduction of Hypoxic Signaling via Reactive Oxygen Species Production","volume":"177","author":"Bell","year":"2007","journal-title":"J. Cell Biol."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"194829","DOI":"10.1155\/2012\/194829","article-title":"Bisphenol a Induces Hepatotoxicity through Oxidative Stress in Rat Model","volume":"2012","author":"Hassan","year":"2012","journal-title":"Oxidative Med. Cell. Longev."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"507","DOI":"10.3109\/15376516.2015.1056395","article-title":"Effect of Bisphenol A on Blood Glucose, Lipid Profile and Oxidative Stress Indices in Adult Male Mice","volume":"25","author":"Moghaddam","year":"2015","journal-title":"Toxicol. Mech. Methods"},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0013-9351(03)00062-8","article-title":"Effects of Bisphenol A on the Metabolisms of Active Oxygen Species in Mouse Tissues","volume":"93","author":"Kabuto","year":"2003","journal-title":"Environ. Res."},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1021\/acs.est.2c06488","article-title":"Co-Exposure to Bisphenols, Parabens, and Antimicrobials and Association with Coronary Heart Disease: Oxidative Stress as a Potential Mediating Factor?","volume":"57","author":"Zhang","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1002\/tox.22702","article-title":"Expression of Pro-Inflammatory Cytokines and Mediators Induced by Bisphenol A via ERK-NF\u03baB and JAK1\/2-STAT3 Pathways in Macrophages","volume":"34","author":"Huang","year":"2019","journal-title":"Environ. Toxicol."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1007\/s12291-017-0667-0","article-title":"Study of the Effect of Bisphenol A on Oxidative Stress in Children with Autism Spectrum Disorders","volume":"33","author":"Metwally","year":"2018","journal-title":"Indian J. Clin. Biochem."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.envint.2018.04.023","article-title":"Advanced Data Mining Approaches in the Assessment of Urinary Concentrations of Bisphenols, Chlorophenols, Parabens and Benzophenones in Brazilian Children and Their Association to DNA Damage","volume":"116","author":"Rocha","year":"2018","journal-title":"Environ. Int."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"2217","DOI":"10.1016\/j.fct.2010.05.051","article-title":"Bisphenol A 3,4-Quinone Induces the Conversion of Xanthine Dehydrogenase into Oxidase in Vitro","volume":"48","author":"Sakuma","year":"2010","journal-title":"Food Chem. Toxicol."},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1146\/annurev.biochem.72.121801.161647","article-title":"Copper-Zinc Superoxide Dismutase and Amyotrophic Lateral Sclerosis","volume":"74","author":"Valentine","year":"2005","journal-title":"Annu. Rev. Biochem."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s12276-019-0355-7","article-title":"Mitochondrial Dysfunction and Oxidative Stress in Heart Disease","volume":"51","author":"Peoples","year":"2019","journal-title":"Exp. Mol. Med."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1161\/01.RES.86.3.347","article-title":"Transcriptional and Posttranscriptional Regulation of Endothelial Nitric Oxide Synthase Expression by Hydrogen Peroxide","volume":"86","author":"Drummond","year":"2000","journal-title":"Circ. Res."},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"967","DOI":"10.15244\/pjoes\/76038","article-title":"Effect of Bisphenol A-Induced Oxidative Stress on the Ultra Structure and Antioxidant Defence System of Arabidopsis Thialiana Leaves","volume":"27","author":"Ali","year":"2018","journal-title":"Pol. J. Environ. Stud."},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"113701","DOI":"10.1016\/j.fct.2023.113701","article-title":"Safer Alternatives? Bisphenol F and Bisphenol S Induce Oxidative Stress in Drosophila Melanogaster Larvae and Trigger Developmental Damage","volume":"175","author":"Poetini","year":"2023","journal-title":"Food Chem. Toxicol."},{"key":"ref_96","doi-asserted-by":"crossref","unstructured":"Nguyen, M., Sabry, R., Davis, O.S., and Favetta, L.A. (2022). Effects of BPA, BPS, and BPF on Oxidative Stress and Antioxidant Enzyme Expression in Bovine Oocytes and Spermatozoa. Genes, 13.","DOI":"10.3390\/genes13010142"},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.scitotenv.2019.03.129","article-title":"Searching for a Bisphenol A Substitute: Effects of Bisphenols on Catalase Molecules and Human Red Blood Cells","volume":"669","author":"Zhang","year":"2019","journal-title":"Sci. Total Environ."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1111\/j.1476-5381.2010.00687.x","article-title":"Bisphenol A Activates Maxi-K (K Ca1.1) Channels in Coronary Smooth Muscle","volume":"160","author":"Asano","year":"2010","journal-title":"Br. J. Pharmacol."},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1080\/15376516.2020.1836102","article-title":"Effects of Bisphenol A and S on Blood Coagulation: In Vivo, in Vitro and in Silico Approaches in Toxicodynamic","volume":"31","author":"Chagas","year":"2021","journal-title":"Toxicol. Mech. Methods"},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1016\/j.toxrep.2017.10.006","article-title":"Bisphenol S Impairs Blood Functions and Induces Cardiovascular Risks in Rats","volume":"4","author":"Pal","year":"2017","journal-title":"Toxicol. Rep."},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"152742","DOI":"10.1016\/j.tox.2021.152742","article-title":"Bisphenol AF Elevates Procoagulant Platelets by Inducing Necroptosis via RIPK1-Inflammasome Axis","volume":"454","author":"Vishalakshi","year":"2021","journal-title":"Toxicology"},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s00210-013-0932-6","article-title":"Bisphenol A Differently Inhibits CaV3.1, CaV3.2 and CaV3.3 Calcium Channels","volume":"387","author":"Michaela","year":"2014","journal-title":"Naunyn-Schmiedeberg\u2019s Arch. Pharmacol."},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"4127","DOI":"10.1074\/jbc.M310341200","article-title":"Characterization of Superoxide-Producing Sites in Isolated Brain Mitochondria","volume":"279","author":"Kudin","year":"2004","journal-title":"J. Biol. Chem."},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/j.bbabio.2008.04.037","article-title":"The Q-Cycle Reviewed: How Well Does a Monomeric Mechanism of the Bc1 Complex Account for the Function of a Dimeric Complex?","volume":"1777","author":"Crofts","year":"2008","journal-title":"Biochim. Biophys. Acta Bioenerg."},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S0005-2728(03)00059-8","article-title":"The Nuclear Encoded Subunits of Complex I from Bovine Heart Mitochondria","volume":"1604","author":"Hirst","year":"2003","journal-title":"Biochim. Biophys. Acta Bioenerg."},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"106354","DOI":"10.1016\/j.aquatox.2022.106354","article-title":"Bisphenols Induce Cardiotoxicity in Zebrafish Embryos: Role of the Thyroid Hormone Receptor Pathway","volume":"254","author":"Qin","year":"2023","journal-title":"Aquat. Toxicol."},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1093\/toxsci\/kfu030","article-title":"Are Structural Analogues to Bisphenol a Safe Alternatives?","volume":"139","author":"Rosenmai","year":"2014","journal-title":"Toxicol. Sci."},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"160762","DOI":"10.1016\/j.scitotenv.2022.160762","article-title":"In Vitro and in Silico Assessment of GPER-Dependent Neurocytotoxicity of Emerging Bisphenols","volume":"862","author":"Wang","year":"2023","journal-title":"Sci. Total Environ."},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.pharmthera.2012.03.007","article-title":"Estrogen and the Cardiovascular System","volume":"135","author":"Knowlton","year":"2012","journal-title":"Pharmacol. Ther."},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"114197","DOI":"10.1016\/j.fct.2023.114197","article-title":"Bisphenol A (BPA) Exposure Aggravates Hepatic Oxidative Stress and Inflammatory Response under Hypertensive Milieu\u2014Impact of Low Dose on Hepatocytes and Influence of MAPK and ER Stress Pathways","volume":"183","author":"Nagarajan","year":"2024","journal-title":"Food Chem. Toxicol."},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"128997","DOI":"10.1016\/j.chemosphere.2020.128997","article-title":"Impairment of Sirtuin 1-Mediated DNA Repair Is Involved in Bisphenol A-Induced Aggravation of Macrophage Inflammation and Atherosclerosis","volume":"265","author":"Yang","year":"2021","journal-title":"Chemosphere"},{"key":"ref_112","first-page":"433","article-title":"Estrogen Receptor-Regulated SOCS3 Modulation via JAK2\/STAT3 Pathway Is Involved in BPF-Induced M1 Polarization of Macrophages","volume":"433","author":"Shi","year":"2020","journal-title":"Toxicology"},{"key":"ref_113","doi-asserted-by":"crossref","unstructured":"Ratajczak-Wrona, W., Rusak, M., Nowak, K., Dabrowska, M., Radziwon, P., and Jablonska, E. (2020). Effect of Bisphenol A on Human Neutrophils Immunophenotype. Sci. Rep., 10.","DOI":"10.1038\/s41598-020-59753-2"},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1152\/ajpcell.00242.2017","article-title":"Alterations in Human Neutrophil Function Caused by Bisphenol A","volume":"315","author":"Balistrieri","year":"2018","journal-title":"J. Physiol.-Cell Physiol."},{"key":"ref_115","first-page":"1","article-title":"Sex-Dependent Dysregulation of Human Neutrophil Responses by Bisphenol A","volume":"20","author":"Garley","year":"2021","journal-title":"Environ. Health"},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"113558","DOI":"10.1016\/j.ecoenv.2022.113558","article-title":"Cineole Alleviates the BPA-Inhibited NETs Formation by Regulating the P38 Pathway-Mediated Programmed Cell Death","volume":"237","author":"Chen","year":"2022","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"ref_117","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1002\/JLB.2MR0220-549R","article-title":"ICAM-1: A Master Regulator of Cellular Responses in Inflammation, Injury Resolution, and Tumorigenesis","volume":"108","author":"Bui","year":"2020","journal-title":"J. Leukoc. Biol."},{"key":"ref_118","doi-asserted-by":"crossref","unstructured":"Wautier, J.L., and Wautier, M.P. (2022). Vascular Permeability in Diseases. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms23073645"},{"key":"ref_119","doi-asserted-by":"crossref","unstructured":"Russo, C., Maugeri, A., Albergamo, A., Dugo, G., Navarra, M., and Cirmi, S. (2023). Protective Effects of a Red Grape Juice Extract against Bisphenol A-Induced Toxicity in Human Umbilical Vein Endothelial Cells. Toxics, 11.","DOI":"10.3390\/toxics11040391"},{"key":"ref_120","doi-asserted-by":"crossref","unstructured":"Aftabsavad, S., Noormohammadi, Z., Moini, A., and Karimipoor, M. (2021). Effect of Bisphenol A on Alterations of ICAM-1 and HLA-G Genes Expression and DNA Methylation Profiles in Cumulus Cells of Infertile Women with Poor Response to Ovarian Stimulation. Sci. Rep., 11.","DOI":"10.1038\/s41598-021-87175-1"},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.reprotox.2018.10.009","article-title":"Bisphenol-A Impairs Cellular Function and Alters DNA Methylation of Stress Pathway Genes in First Trimester Trophoblast Cells","volume":"82","author":"Basak","year":"2018","journal-title":"Reprod. Toxicol."},{"key":"ref_122","doi-asserted-by":"crossref","first-page":"109382","DOI":"10.1016\/j.envres.2020.109382","article-title":"Bisphenol A Exposure in Relation to Altered Lipid Profile and Dyslipidemia among Chinese Adults: A Repeated Measures Study","volume":"184","author":"Wang","year":"2020","journal-title":"Environ. Res."},{"key":"ref_123","doi-asserted-by":"crossref","first-page":"25093","DOI":"10.1007\/s11356-021-15589-5","article-title":"Urinary Phenols and Parabens Metabolites Associated with Cardiovascular Disease among Adults in the United States","volume":"30","author":"Yin","year":"2023","journal-title":"Environ. Sci. Pollut. Res."},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"42947","DOI":"10.1007\/s11356-021-18323-3","article-title":"Association between Urinary Environmental Phenols and the Prevalence of Cardiovascular Diseases in US Adults","volume":"29","author":"Chen","year":"2022","journal-title":"Environ. Sci. Pollut. Res."},{"key":"ref_125","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1161\/CIRCULATIONAHA.111.069153","article-title":"Urinary Bisphenol A Concentration and Risk of Future Coronary Artery Disease in Apparently Healthy Men and Women","volume":"125","author":"Melzer","year":"2012","journal-title":"Circulation"},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1289\/ehp.1104114","article-title":"Bisphenol A and Peripheral Arterial Disease: Results from the NHANES","volume":"120","author":"Shankar","year":"2012","journal-title":"Environ. Health Perspect."},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1093\/aje\/kws391","article-title":"Urinary Bisphenol a and Obesity in US Children","volume":"177","author":"Bhandari","year":"2013","journal-title":"Am. J. Epidemiol."},{"key":"ref_128","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1186\/s12967-015-0532-y","article-title":"Bisphenol-A Plasma Levels Are Related to Inflammatory Markers, Visceral Obesity and Insulin-Resistance: A Cross-Sectional Study on Adult Male Population","volume":"13","author":"Savastano","year":"2015","journal-title":"J. Transl. Med."},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1007\/s11356-016-7806-7","article-title":"Exposure to Bisphenol A Is Directly Associated with Inflammation in Healthy Korean Adults","volume":"24","author":"Choi","year":"2017","journal-title":"Environ. Sci. Pollut. Res."},{"key":"ref_130","doi-asserted-by":"crossref","first-page":"e2011620","DOI":"10.1001\/jamanetworkopen.2020.11620","article-title":"Association between Bisphenol A Exposure and Risk of All-Cause and Cause-Specific Mortality in US Adults","volume":"3","author":"Bao","year":"2020","journal-title":"JAMA Netw. Open"},{"key":"ref_131","doi-asserted-by":"crossref","first-page":"113639","DOI":"10.1016\/j.envpol.2019.113639","article-title":"Association of Bisphenol A and Its Alternatives Bisphenol S and F Exposure with Hypertension and Blood Pressure: A Cross-Sectional Study in China","volume":"257","author":"Jiang","year":"2020","journal-title":"Environ. Pollut."},{"key":"ref_132","doi-asserted-by":"crossref","first-page":"32580","DOI":"10.1007\/s11356-021-12805-0","article-title":"Study on the Correlation of Bisphenol A Exposure, pro-Inflammatory Gene Expression, and C-Reactive Protein with Potential Cardiovascular Disease Symptoms in Young Adults","volume":"28","author":"Tsen","year":"2021","journal-title":"Environ. Sci. Pollut. Res."},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1186\/s12940-022-00945-w","article-title":"Serum Glycolipids Mediate the Relationship of Urinary Bisphenols with NAFLD: Analysis of a Population-Based, Cross-Sectional Study","volume":"21","author":"Peng","year":"2022","journal-title":"Environ. Health"},{"key":"ref_134","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1002\/jat.4401","article-title":"Associations of Bisphenol F and S, as Substitutes for Bisphenol A, with Cardiovascular Disease in American Adults","volume":"43","author":"Lu","year":"2023","journal-title":"J. Appl. Toxicol."},{"key":"ref_135","doi-asserted-by":"crossref","unstructured":"Rubinstein, J., Pinney, S.M., Xie, C., and Wang, H.-S. (2024). Association of Same-Day Urinary Phenol Levels and Cardiac Electrical Alterations: Analysis of the Fernald Community Cohort. Environ. Health, 2.","DOI":"10.21203\/rs.3.rs-4445657\/v1"},{"key":"ref_136","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1161\/CIRCRESAHA.111.246876","article-title":"The Intersection between Aging and Cardiovascular Disease","volume":"110","author":"North","year":"2012","journal-title":"Circ. Res."},{"key":"ref_137","doi-asserted-by":"crossref","first-page":"47007","DOI":"10.1289\/EHP10293","article-title":"Maternal Phthalate and Bisphenol Urine Concentrations during Pregnancy and Early Markers of Arterial Health in Children","volume":"130","author":"Blaauwendraad","year":"2022","journal-title":"Environ. Health Perspect."},{"key":"ref_138","doi-asserted-by":"crossref","first-page":"153991","DOI":"10.1016\/j.scitotenv.2022.153991","article-title":"Triglyceride Profiles Are Associated with Subacute Exposure to Bisphenol A in Healthy Young Adults","volume":"825","author":"Lu","year":"2022","journal-title":"Sci. Total Environ."},{"key":"ref_139","doi-asserted-by":"crossref","first-page":"6141","DOI":"10.1007\/s11357-024-01193-1","article-title":"Association of Vitamin D and Bisphenol A Levels with Cardiovascular Risk in an Elderly Italian Population: Results from the InCHIANTI Study","volume":"46","author":"Brandi","year":"2024","journal-title":"Geroscience"}],"container-title":["Antioxidants"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-3921\/13\/12\/1468\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T16:42:22Z","timestamp":1760114542000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-3921\/13\/12\/1468"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,29]]},"references-count":139,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["antiox13121468"],"URL":"https:\/\/doi.org\/10.3390\/antiox13121468","relation":{},"ISSN":["2076-3921"],"issn-type":[{"value":"2076-3921","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,29]]}}}