{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T01:26:28Z","timestamp":1784942788886,"version":"3.55.0"},"reference-count":96,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T00:00:00Z","timestamp":1733961600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antioxidants"],"abstract":"<jats:p>Papaya fruit is commonly known for its nutritional and medicinal value. It is a perennial, herbaceous, and trioecious cross-pollinated species with male, female, and hermaphrodite plants. The Chilean papaya, originating from South America, has been extensively spread throughout the Andean nations, cultivated primarily in the Coquimbo and Valpara\u00edso valleys in Chile, between 34\u00b041\u2032 and 36\u00b033\u2032 latitude south. Its intense aroma, yellow color, and oblong shape characterize this fruit. It also stands out for its high content of carotenoids, vitamins, proteins, and polysaccharides, which make it a great functional food. Also, papaya contains bioactive compounds with antifungal, anti-inflammatory, and wound-healing effects. For years, the fruit has been used to produce canned fruit, juice, and candies to satisfy the local market. Chilean papaya has significant economic importance, supplying both local and international markets. This review aims to consolidate the evidence-based information on the native Chilean papaya (Vasconcellea pubescens) as a food matrix. The fruit\u2019s ripening process, nutritional composition, industrial applications, and health-promoting properties, including its antioxidant and antidiabetic effects, are thoroughly examined. Additionally, the extraction of papaya oil, encapsulation of bioactive compounds, industrial and artisanal processing techniques, and patents are explored, highlighting the diverse applications and potential benefits of this fruit.<\/jats:p>","DOI":"10.3390\/antiox13121521","type":"journal-article","created":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T09:38:15Z","timestamp":1733996295000},"page":"1521","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Chilean Papaya (Vasconcellea pubescens): A Native Fruit with a High Health-Promoting Functional Potential"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1252-2573","authenticated-orcid":false,"given":"Roberto","family":"Lemus-Mondaca","sequence":"first","affiliation":[{"name":"Department of Food Science and Chemical Technology, Faculty of Chemical Sciences and Pharmaceutical, Universidad de Chile, St. Dr. Carlos Lorca 964, Independencia, Santiago 8380494, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5214-8766","authenticated-orcid":false,"given":"Luis","family":"Puente-D\u00edaz","sequence":"additional","affiliation":[{"name":"Department of Food Science and Chemical Technology, Faculty of Chemical Sciences and Pharmaceutical, Universidad de Chile, St. Dr. Carlos Lorca 964, Independencia, Santiago 8380494, Chile"},{"name":"Department of Agricultural, Food & Nutritional Science, University of Alberta, Edmonton, AB T6G 2P5, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ang\u00e9lica","family":"Cifuentes","sequence":"additional","affiliation":[{"name":"Department of Food Science and Chemical Technology, Faculty of Chemical Sciences and Pharmaceutical, Universidad de Chile, St. Dr. Carlos Lorca 964, Independencia, Santiago 8380494, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Lizama","sequence":"additional","affiliation":[{"name":"Department of Food Science and Chemical Technology, Faculty of Chemical Sciences and Pharmaceutical, Universidad de Chile, St. Dr. Carlos Lorca 964, Independencia, Santiago 8380494, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Department of Food Science and Chemical Technology, Faculty of Chemical Sciences and Pharmaceutical, Universidad de Chile, St. Dr. Carlos Lorca 964, Independencia, Santiago 8380494, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,12,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"347532","DOI":"10.1155\/2015\/347532","article-title":"Extraction techniques for bioactive compounds and antioxidant capacity determination of Chilean papaya (Vasconcellea pubescens) fruit","volume":"2015","author":"Uribe","year":"2015","journal-title":"J. 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