{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T00:43:33Z","timestamp":1759970613524,"version":"build-2065373602"},"reference-count":29,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2025,1,23]],"date-time":"2025-01-23T00:00:00Z","timestamp":1737590400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Recovery and Resilience Facility of the European Union within the framework of Programme Sz\u00e9chenyi Plan Plus","award":["RRF-2.3.1-21-2022-00012"],"award-info":[{"award-number":["RRF-2.3.1-21-2022-00012"]}]},{"name":"HUN-REN Hungarian Research Network","award":["RRF-2.3.1-21-2022-00012"],"award-info":[{"award-number":["RRF-2.3.1-21-2022-00012"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antioxidants"],"abstract":"<jats:p>This preliminary study was designed to determine follicular fluid (FF) vanin-1 levels, to assess their relation to serum vanin-1 and to reveal their potential to predict the outcome of in vitro fertilization (IVF). Eighteen unselected, consecutive women undergoing IVF were included. Serum and pooled FF samples were obtained simultaneously during routine IVF procedures. Vanin-1 levels were measured by using commercially available ELISA kits. As most of the values were below 0.6 ng\/mL, the data are given as optical density. It was found that vanin-1 can be detected in FF and that it is not significantly related to its maternal serum levels (p = 0.06). FF vanin-1 levels proved to be higher in non-pregnant as compared to pregnant women (p &lt; 0.04). There are significant positive relationships between the FF to serum vanin-1 ratio and body mass index (BMI, p &lt; 0.02), anti-M\u00fcllerian hormone (AMH, p &lt; 0.02) and baseline serum estradiol (p &lt; 0.01). Moreover, the FF\/serum vanin-1 ratio tended to increase with cumulative FSH dose, but this increase did not reach statistical significance (p = 0.064). It may be concluded that FF vanin-1 may serve as a biomarker to predict IVF outcome. To confirm this contention, further studies are to be performed.<\/jats:p>","DOI":"10.3390\/antiox14020133","type":"journal-article","created":{"date-parts":[[2025,1,23]],"date-time":"2025-01-23T12:24:09Z","timestamp":1737635049000},"page":"133","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Follicular Fluid Vanin-1 Levels in Patients Undergoing Ivf: A Preliminary Study"],"prefix":"10.3390","volume":"14","author":[{"given":"\u00c1kos","family":"V\u00e1rnagy","sequence":"first","affiliation":[{"name":"National Laboratory on Human Reproduction, University of P\u00e9cs, H-7624 P\u00e9cs, Hungary"},{"name":"HUN-REN\u2013PTE Human Reproduction Research Group, H-7624 P\u00e9cs, Hungary"},{"name":"Department of Obstetrics and Gynecology, School of Medicine, University of P\u00e9cs, H-7624 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P\u00e9ter","family":"Mauchart","sequence":"additional","affiliation":[{"name":"National Laboratory on Human Reproduction, University of P\u00e9cs, H-7624 P\u00e9cs, Hungary"},{"name":"HUN-REN\u2013PTE Human Reproduction Research Group, H-7624 P\u00e9cs, Hungary"},{"name":"Department of Obstetrics and Gynecology, School of Medicine, University of P\u00e9cs, H-7624 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2943-2750","authenticated-orcid":false,"given":"G\u00e1bor","family":"Nagy","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00f3zsef","family":"B\u00f3dis","sequence":"additional","affiliation":[{"name":"National Laboratory on Human Reproduction, University of P\u00e9cs, H-7624 P\u00e9cs, Hungary"},{"name":"HUN-REN\u2013PTE Human Reproduction Research Group, H-7624 P\u00e9cs, Hungary"},{"name":"Department of Obstetrics and Gynecology, School of Medicine, University of P\u00e9cs, H-7624 P\u00e9cs, Hungary"},{"name":"Doctoral School of Health Sciences, Faculty of Health Sciences, University of P\u00e9cs, H-7624 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Endre","family":"Sulyok","sequence":"additional","affiliation":[{"name":"National Laboratory on Human Reproduction, University of P\u00e9cs, H-7624 P\u00e9cs, Hungary"},{"name":"HUN-REN\u2013PTE Human Reproduction Research Group, H-7624 P\u00e9cs, Hungary"},{"name":"Doctoral School of Health Sciences, Faculty of Health Sciences, University of P\u00e9cs, H-7624 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,1,23]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/s12014-015-9077-6","article-title":"Poteomic analysis of follicular fluid from fertile women","volume":"12","author":"Zaman","year":"2015","journal-title":"Clin. 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