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This paper aims to highlight these characteristics to facilitate the selection of extracts according to market needs. The analyzed parameters can provide valuable insights into the compositional variability of the five red flower plants, as new sources of bioactive compounds and natural antioxidants of plant origin. Five plants with red flowers (Magnolia liliiflora, Chrysanthemum morifolium, Hibiscus sabdariffa, Petunia grandiflora, Rosa hybrida L.) were selected and investigated regarding their polyphenol concentration, total anthocyanins, antioxidant activity, phenolic compounds, and antimicrobial activity. Total polyphenols were found in concentrations ranging from 75.17 \u00b1 0.16 mgGAE\/g (C. morifolium) to 107.49 \u00b1 0.19 mgGAE\/g (R. hybrida L.), and total anthocyanins between 14.99 \u00b1 0.13 mg Cy-3-Glu\/g and 21.66 \u00b1 0.18 mg Cy-3-Glu\/g. The antioxidant activity DPPH\/IC50 mg\/mL for the extract from R. hybrida L. flowers reached a value of 29.35 \u00b1 0.17 mg\/g, with ABTS and FRAP achieving maximum values of 49.89 \u00b1 0.24 mmol TE\/g and 48.68 \u00b1 0.23 mmol TE\/g, respectively. The antibacterial activity was particularly evident against strains commonly encountered in human pathology, Escherichia coli and Staphylococcus aureus, with reduced or no impact on strains of Pseudomonas fluorescens and Proteus mirabilis. The results demonstrated that the extracts from the selected, red-flowered plants contain valuable biologically active compounds in generous quantities, thus recommending their use in the food, pharmaceutical, and medical sectors.<\/jats:p>","DOI":"10.3390\/antiox14020151","type":"journal-article","created":{"date-parts":[[2025,1,27]],"date-time":"2025-01-27T09:42:23Z","timestamp":1737970943000},"page":"151","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Investigation of Phytochemical Composition, Antioxidant and Antibacterial Activity of Five Red Flower Extracts"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3442-3760","authenticated-orcid":false,"given":"Diana Ionela","family":"Popescu (Stegarus)","sequence":"first","affiliation":[{"name":"National Research and Development Institute for Cryogenic and Isotopic Technologies\u2014ICSI Ramnicu Valcea, 240050 Ramnicu Valcea, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0972-9813","authenticated-orcid":false,"given":"Oana Romina","family":"Botoran","sequence":"additional","affiliation":[{"name":"National Research and Development Institute for Cryogenic and Isotopic Technologies\u2014ICSI Ramnicu Valcea, 240050 Ramnicu Valcea, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8411-1207","authenticated-orcid":false,"given":"Ramona Maria (Iancu)","family":"Cristea","sequence":"additional","affiliation":[{"name":"Department of Agricultural Science and Food Engineering, \u201cLucian Blaga\u201d University of Sibiu, 7-9 Dr. Ion Ratiu, 550024 Sibiu, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,1,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1515\/aucft-2015-0009","article-title":"Antimicrobial Effect of E. coli on Essential Oils Derived from Romanian Aromatic Plants","volume":"19","year":"2015","journal-title":"Acta Univ. 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