{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T03:27:51Z","timestamp":1788406071163,"version":"build-2803163510"},"reference-count":67,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T00:00:00Z","timestamp":1780444800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Natural Science Foundation Project of Sichuan Province","award":["2025ZNSFSC1049"],"award-info":[{"award-number":["2025ZNSFSC1049"]}]},{"name":"Sichuan Provincial Administration of Traditional Chinese Medicine\u2019s 2025 Special Project for Medical Research in Traditional Chinese Medicine","award":["25MSZX569"],"award-info":[{"award-number":["25MSZX569"]}]},{"name":"Pioneer and Leading Goose R&D Project of Zhejiang Province","award":["2026C04014"],"award-info":[{"award-number":["2026C04014"]}]},{"name":"Sichuan Academy of Agricultural Sciences https:\/\/ror.org\/05f0php28","award":["1+9KJGG007"],"award-info":[{"award-number":["1+9KJGG007"]}]},{"award":["1+9KJGG007"],"award-info":[{"award-number":["1+9KJGG007"]}],"id":[{"id":"https:\/\/ror.org\/05f0php28","id-type":"ROR","asserted-by":"publisher"}]},{"name":"Innovation Team Project of Sichuan Province Authentic Chinese Medicine","award":["SCCXTD-2020-19"],"award-info":[{"award-number":["SCCXTD-2020-19"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antioxidants"],"abstract":"<jats:p>In this study, 20% ethanol elution fraction(PC-20), 40% ethanol elution fraction(PC-40), 60% ethanol elution fraction(PC-60), and 80% ethanol elution fraction (PC-80)of Penthorum chinense polyphenols were obtained using AB-8 macroporous resin . Their in vitro bioactivities were compared to explore potential applications. A comprehensive phytochemical analysis identified 85 compounds, including 16 phenolic acids, 36 flavonoids, 24 hydrolyzed tannins, 7 anthocyanins, and 2 others. The results showed clear ethanol concentration-dependent variations in both compound composition and bioactivity. PC-20 had the highest levels of total polyphenols (418.45 mg\/g), proanthocyanidins (84.95 mg\/g), and tannins (10.61 mg\/g), and also showed the best antioxidant capacity. PC-40 contained the most flavonoids (227.55 mg\/g). PC-60 gave the strongest \u03b1-glucosidase inhibition (IC50 = 0.79 \u00b5g\/mL), while PC-20 was most effective against pancreatic lipase (IC50 = 101.06 \u00b5g\/mL) and also significantly activated the enzymes ADH and ALDH. Overall, PC-20 appears more suitable for applications aimed at antioxidant, anti-obesity, or liver-protective effects, whereas PC-60 is more promising for blood glucose control. This work provides a practical basis for selecting different ethanol fractions of P. chinense polyphenols according to specific functional needs.<\/jats:p>","DOI":"10.3390\/antiox15060709","type":"journal-article","created":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T18:08:07Z","timestamp":1780510087000},"page":"709","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Macroporous Resin Purification of Phenolics from Penthorumchinense Leaves: Phenolic Identification, Composition Analysis, and Biological Activities"],"prefix":"10.3390","volume":"15","author":[{"given":"Qian","family":"Lai","sequence":"first","affiliation":[{"name":"Gulin County Agricultural Technology Extension and Service Center, Gulin 646500, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junlin","family":"Deng","sequence":"additional","affiliation":[{"name":"Institute of Agro-Products Processing Science and Technology (Institute of Food Nutrition and Health), Sichuan Academy of Agricultural Sciences, 60 Shizishan Road, Chengdu 610066, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8321-5741","authenticated-orcid":false,"given":"Manyou","family":"Yu","sequence":"additional","affiliation":[{"name":"Institute of Agro-Products Processing Science and Technology (Institute of Food Nutrition and Health), Sichuan Academy of Agricultural Sciences, 60 Shizishan Road, Chengdu 610066, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Gan","sequence":"additional","affiliation":[{"name":"Institute of Agro-Products Processing Science and Technology (Institute of Food Nutrition and Health), Sichuan Academy of Agricultural Sciences, 60 Shizishan Road, Chengdu 610066, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongqing","family":"Zhu","sequence":"additional","affiliation":[{"name":"Institute of Agro-Products Processing Science and Technology (Institute of Food Nutrition and Health), Sichuan Academy of Agricultural Sciences, 60 Shizishan Road, Chengdu 610066, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Xia","sequence":"additional","affiliation":[{"name":"Institute of Agro-Products Processing Science and Technology (Institute of Food Nutrition and Health), Sichuan Academy of Agricultural Sciences, 60 Shizishan Road, Chengdu 610066, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youmin","family":"Ying","sequence":"additional","affiliation":[{"name":"College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhuoya","family":"Xiang","sequence":"additional","affiliation":[{"name":"Institute of Agro-Products Processing Science and Technology (Institute of Food Nutrition and Health), Sichuan Academy of Agricultural Sciences, 60 Shizishan Road, Chengdu 610066, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,6,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"4254051","DOI":"10.1155\/2023\/4254051","article-title":"An Updated Review on Efficiency of Penthorum chinense Pursh in Traditional Uses, Toxicology, and Clinical Trials","volume":"2023","author":"Nabi","year":"2023","journal-title":"Biomed. 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