{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T06:48:25Z","timestamp":1782456505237,"version":"3.54.5"},"reference-count":61,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T00:00:00Z","timestamp":1781481600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antioxidants"],"abstract":"<jats:p>The genus Capsicum is widely used worldwide for its culinary value and functional potential. The objective of this study was to evaluate the bioactive compounds, antioxidant and antimicrobial activity of sweet and hot pepper at different stages of ripeness. Six varieties of peppers at five stages of ripeness were analysed. Mineral parameters (Ca, Fe, Na, K, Mg) were determined by atomic absorption spectrophotometry, while bioactive compounds (vitamin C, organic acids, carotenoids, and phenols) were analysed by liquid chromatography. Antioxidant activity was evaluated using ABTS and DPPH assays, and antimicrobial activity was assessed by minimum inhibitory concentration against bacteria and yeasts. Multivariate analyses (PCA and heatmap) were carried out at a significance level of p &lt; 0.05. The results showed that genotype was the main determinant of variability, surpassing the effect of ripeness. Potassium was the predominant mineral (3431.5 mg\/100 g DW) in Malagueta chilli M5. Variety-specific peaks were identified, notably vitamin C in Habanero chilli (M3) (10,319.5 mg\/100 g DW), capsaicin in Malagueta chilli (M5) (1949.8 mg\/100 g DW), and carotenoids in Orange medium peppers (M5) (9495.8 mg\/100 g DW). Antioxidant activity was higher in hot varieties (41.3 mmol ET\/100 g DW in Habanero chilli (M2) by DPPH), while antimicrobial activity varied against Escherichia coli (2.6 mg\/mL in Yellow medium peppers (M4)), Staphylococcus aureus (5.2 mg\/mL in Orange medium pepper), and Streptococcus mutans (2.0 mg\/mL in Jalape\u00f1o chilli), with low MIC values. Multivariate analyses confirmed that chemical and biological variability is primarily structured by genotype.<\/jats:p>","DOI":"10.3390\/antiox15060756","type":"journal-article","created":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T08:22:56Z","timestamp":1781684576000},"page":"756","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Bioactive Profile, Antioxidant, and Antimicrobial Activity of Sweet and Hot Peppers at Different Stages of Ripeness"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4495-3500","authenticated-orcid":false,"given":"Elena","family":"Coyago-Cruz","sequence":"first","affiliation":[{"name":"Carrera de Ingenier\u00eda en Biotecnolog\u00eda, Universidad Polit\u00e9cnica Salesiana, Sede Quito, Campus El Gir\u00f3n, Av. 12 de Octubre N2422 y Wilson, Quito 170109, Ecuador"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5903-6735","authenticated-orcid":false,"given":"Gabriela","family":"M\u00e9ndez","sequence":"additional","affiliation":[{"name":"Carrera de Ingenier\u00eda en Biotecnolog\u00eda, Universidad Polit\u00e9cnica Salesiana, Sede Quito, Campus El Gir\u00f3n, Av. 12 de Octubre N2422 y Wilson, Quito 170109, Ecuador"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-2994-7630","authenticated-orcid":false,"given":"Santiago","family":"Buyancela","sequence":"additional","affiliation":[{"name":"Carrera de Ingenier\u00eda en Biotecnolog\u00eda, Universidad Polit\u00e9cnica Salesiana, Sede Quito, Campus El Gir\u00f3n, Av. 12 de Octubre N2422 y Wilson, Quito 170109, Ecuador"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-1559-6010","authenticated-orcid":false,"given":"F\u00e1tima","family":"Rodr\u00edguez-Mu\u00f1oz","sequence":"additional","affiliation":[{"name":"Carrera de Ingenier\u00eda en Biotecnolog\u00eda, Universidad Polit\u00e9cnica Salesiana, Sede Quito, Campus El Gir\u00f3n, Av. 12 de Octubre N2422 y Wilson, Quito 170109, Ecuador"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7620-9140","authenticated-orcid":false,"given":"Jorge","family":"Heredia-Moya","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica (CENBIO), Facultad de Ciencias de la Salud Eugenio Espejo, Universidad UTE, Quito 170527, Ecuador"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,6,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Bharti, H., Hemalatha, N., Malita, R., Sharma, V.K., Bharadwaj, R., and Babu, P. (2026). Phytochemical Characterization and Correlation Analysis of Nutritional Value in Sweet Pepper (Capsicum annuum L.) Genotypes at Various Growth Stages. Front. Plant Sci., 16.","DOI":"10.3389\/fpls.2025.1719537"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3897\/phytokeys.200.71667","article-title":"Monograph of Wild and Cultivated Chili Peppers (Capsicum L., Solanaceae)","volume":"200","author":"Barboza","year":"2022","journal-title":"PhytoKeys"},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Akbar, Z., Mustika, H., Rini, D., Manik, L., Indrawati, A., Fefirenta, A., and Djarwaningsih, T. (2021). An Ontology-Driven Personalized Faceted Search for Exploring Knowledge Bases of Capsicum. Futur. Internet, 13.","DOI":"10.3390\/fi13070172"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"3100","DOI":"10.2135\/cropsci2016.02.0128","article-title":"Deciphering Genetic Diversity in the Origins of Pepper (Capsicum spp.) and Comparison with Worldwide Variability","volume":"56","author":"Silvar","year":"2016","journal-title":"Crop Sci."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"13","DOI":"10.3329\/sja.v21i1.62443","article-title":"Morphogenetic Divergence in Sweet Pepper (Capsicum annum L.) Genotypes","volume":"21","author":"Nadim","year":"2023","journal-title":"SAARC J. Agric."},{"key":"ref_6","first-page":"434","article-title":"Comparative Study on Morphological Characteristics, Ethno Botanical and Ethno Pharmacological Importance of Capsicum annuum L. Var. Annuum and Capsicum annuum L. Var. Frutescens","volume":"44","author":"Kalpana","year":"2024","journal-title":"Agric. Sci. Dig."},{"key":"ref_7","first-page":"1802","article-title":"Genetic Variability Studies in Chilli (Capsicum annuum L.) Genotypes under the Mid Hill Region of Himachal Pradesh, India","volume":"29","author":"TimmaRaro","year":"2023","journal-title":"Ecol. Environ. Conserv."},{"key":"ref_8","first-page":"83","article-title":"Evaluation of Chili Nazla IPB as an Ornamental Chilli for Releasing Variety","volume":"23","author":"Hakim","year":"2023","journal-title":"J. Biol. Trop."},{"key":"ref_9","unstructured":"(2025, April 18). FAO FAOSTAT. Available online: https:\/\/www.fao.org\/statistics\/es."},{"key":"ref_10","first-page":"6050","article-title":"LC-MS\/MS Analysis Elucidates the Different Effects of Industrial and Culinary Processing on Total and Individual (Poly)Phenolic Compounds of Piquillo Pepper (Capsicum annuum Cv. Piquillo)","volume":"71","author":"Cid","year":"2022","journal-title":"J. Agric. Food Chem."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"4563","DOI":"10.1021\/acsomega.1c06532","article-title":"Identification of Phenolic Compounds in Australian-Grown Bell Peppers by Liquid Chromatography Coupled with Electrospray Ionization-Quadrupole-Time-of-Flight-Mass Spectrometry and Estimation of Their Antioxidant Potential","volume":"7","author":"Leng","year":"2022","journal-title":"ACS Omega"},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Guevara, L., Dom\u00ednguez-Anaya, M., Ortigosa, A., Gonz\u00e1lez-Gordo, S., D\u00edaz, C., Vicente, F., Corpas, F., P\u00e9rez, J., and Palma, J. (2021). Identification of Compounds with Potential Therapeutic Uses from Sweet Pepper (Capsicum annuum L.) Fruits and Their Modulation by Nitric Oxide (No). Int. J. Mol. Sci., 22.","DOI":"10.20944\/preprints202103.0675.v1"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"e2572","DOI":"10.1590\/s0102-0536-2023-e2572","article-title":"Vegetables and Their By-Products: Total Phenolic Compound Content, Total Flavonoids, and Antioxidant Activity","volume":"41","author":"Gomes","year":"2023","journal-title":"Hortic. Bras."},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"Gonz\u00e1lez-Burgos, E., and G\u00f3mez-Serranillos, P. (2022). Effect of Phenolic Compounds on Human Health. Nutrients, 13.","DOI":"10.3390\/nu13113922"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"2972","DOI":"10.1111\/1541-4337.12634","article-title":"Capsicum annuum (Hot Pepper): An Ancient Latin-American Crop with Outstanding Bioactive Compounds and Nutraceutical Potential. A Review","volume":"19","author":"Valverde","year":"2020","journal-title":"Compr. Rev. Food Sci. Food Saf."},{"key":"ref_16","unstructured":"Kumara, M., and Ajay, S. (2024). Capsaicinoids, Springer."},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Cho, S., Kim, H., Lee, M., Kim, H., Kim, J., Choe, J., Lee, Y., and Jang, H. (2020). Antioxidant and Anti-inflammatory Activities in Relation to the Flavonoids Composition of Pepper (Capsicum annuum L.). Antioxidants, 9.","DOI":"10.3390\/antiox9100986"},{"key":"ref_18","first-page":"48","article-title":"Antioxidant and Antibacterial Potency of Red Chillies Extract (Capsicum annum Var. Longum)","volume":"8","author":"Ananta","year":"2022","journal-title":"J. Ilm. Medicam."},{"key":"ref_19","first-page":"7372101","article-title":"Effects of Different Solvents Extractions on Total Polyphenol Content, HPLC Analysis, Antioxidant Capacity, and Antimicrobial Properties of Peppers (Red, Yellow, and Green (Capsicum annum L.))","volume":"2022","author":"Mohammad","year":"2022","journal-title":"Evid.-Based Complement. Altern. Med."},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"El-Saber, G., Alqahtani, A., Adeleke, O., Shaheen, H., Wasef, L., Elzeiny, M., Ismail, M., Shalaby, M., Murata, T., and Zaragoza-Bastida, A. (2020). Biological Properties, Bioactive Constituents, and Pharmacokinetics of Some Capsicum spp. And Capsaicinoids. Int. J. Mol. Sci., 21.","DOI":"10.3390\/ijms21155179"},{"key":"ref_21","unstructured":"(2013). M\u00e9todos de Muestreo Recomendados Para La Determinaci\u00f3n de Residuos de Plaguicidas a Efectos Del Cumplimiento de Los LMR (CAC\/GL 33-1999, IDT) (Standard No. CPE-INEN-CODEX-CAC\/GL-33)."},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Coyago-Cruz, E., Guachamin, A., Villac\u00eds, M., Rivera, J., Neto, M., M\u00e9ndez, G., Heredia-Moya, J., and Vera, E. (2023). Evaluation of Bioactive Compounds and Antioxidant Activity in 51 Minor Tropical Fruits of Ecuador. Foods, 12.","DOI":"10.3390\/foods12244439"},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Coyago-Cruz, E., Salazar, I., Guachamin, A., Alomoto, M., Cerna, M., Mendez, G., Heredia-Moya, J., and Vera, E. (2025). Bioactive Compounds, Antioxidant, and Antimicrobial Activity of Seeds and Mucilage of Non-Traditional Cocoas. Antioxidants, 14.","DOI":"10.3390\/antiox14030299"},{"key":"ref_24","first-page":"236","article-title":"The Profile of Capsaicinoids and Pigments Biosynthesis as a Signal for the Ripening and Senescence Processes of Capsicum Fruits","volume":"53","author":"Calva","year":"2022","journal-title":"Rev. CENIC Cienc. Qu\u00edmicas"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1016\/j.foodchem.2017.08.028","article-title":"Antioxidants (Carotenoids and Phenolics) Profile of Cherry Tomatoes as Influenced by Deficit Irrigation, Ripening and Cluster","volume":"240","author":"Corell","year":"2018","journal-title":"Food Chem."},{"key":"ref_26","first-page":"e12710212785","article-title":"Characterization of the Centesimal Composition, Physicochemical, Bioactive Compounds and Antioxidant Capacity of Jalapeno Pepper (Capsicum annuum Var. Annuum Jalapenho)","volume":"10","author":"Ferrari","year":"2021","journal-title":"Res. Soc. Dev."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1590\/0103-8478cr20141795","article-title":"Qualidade P\u00f3s-Colheita e Compostos Funcionais de Pimenta Dedo-de-Mo\u00e7a \u2018BRS Mari\u2019 Em Diferentes Est\u00e1dios de Matura\u00e7\u00e3o","volume":"46","author":"Soethe","year":"2016","journal-title":"Cienc. Rura."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"97","DOI":"10.5154\/r.rchsh.2015.01.004","article-title":"The Organic Acids That Are Accumulated in the Flesh of Fruits: Occurrence, Metabolism and Factors Affecting Their Contents\u2014A Review","volume":"21","author":"Famiani","year":"2015","journal-title":"Rev. Chapingo Ser. Hortic."},{"key":"ref_29","first-page":"139","article-title":"Evaluaci\u00f3n de La Capacidad Antioxidante y Compuestos Bioactivos de Pimiento Morr\u00f3n (Capsicum annuum L.) de Diferentes Colores","volume":"5","year":"2020","journal-title":"Investig. Desarro. Cienc. Tecnol. Aliment."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"7279","DOI":"10.35759\/JAnmPlSci.v42-3.1","article-title":"The Technical Production, Storage and Conservation Routes of Chilli Peppers (Capsicum spp.) Produced in Benin and Constraints Impeding the Development of the Sector","volume":"42","author":"Glodjinon","year":"2019","journal-title":"J. Anim. Plant Sci."},{"key":"ref_31","doi-asserted-by":"crossref","unstructured":"Jim\u00e9nez-P\u00e9rez, M., Moreno-Peris, E., Adalid-Mart\u00ednez, A.M., Fita, A., Raig\u00f3n, M.D., and Rodr\u00edguez-Burruezo, A. (2026). Effect of Fertilization, Irrigation and Microbial Biostimulant on the Antioxidant Profile of Some Sweet Pepper Genotypes. Plants, 15.","DOI":"10.3390\/plants15081278"},{"key":"ref_32","doi-asserted-by":"crossref","unstructured":"Dob\u00f3n-Su\u00e1rez, A., Gim\u00e9nez, M., Castillo, S., Garc\u00eda-Pastor, M., and Zapata, P. (2021). Influence of the Phenological Stage and Harvest Date on the Bioactive Compounds Content of Green Pepper Fruit. Molecules, 26.","DOI":"10.3390\/molecules26113099"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/s10068-022-01177-x","article-title":"Physicochemical Properties and Antioxidant Activity of Colored Peppers (Capsicum annuum L.)","volume":"32","author":"Choi","year":"2023","journal-title":"Food Sci. Biotechnol."},{"key":"ref_34","doi-asserted-by":"crossref","unstructured":"Wang, J., He, J., Zhang, R., Li, N., Zhang, S., Li, J., and Sun, S. (2025). Comparative Study of Pigment Content, Nutrient Composition and Antioxidant Capacity of Different Color Peppers at Different Maturity Stages. Horticulturae, 11.","DOI":"10.3390\/horticulturae11121481"},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Hamed, M., Kalita, D., Bartolo, M.E., and Jayanty, S.S. (2019). Capsaicinoids, Polyphenols and Antioxidant Activities of Capsicum annuum: Comparative Study of the Effect of Ripening Stage and Cooking Methods. Antioxidants, 8.","DOI":"10.3390\/antiox8090364"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"427","DOI":"10.3390\/antiox4020427","article-title":"Bioactive Compounds and Antioxidant Activity in Different Grafted Varieties of Bell Pepper","volume":"4","author":"Sanchez","year":"2015","journal-title":"Antioxidants"},{"key":"ref_37","doi-asserted-by":"crossref","unstructured":"Hassan, N., Yusof, N., Yahaya, A., Rozali, N., and Othman, R. (2019). Carotenoids of Capsicum Fruits: Pigment Profile and Health-Promoting Functional Attributes. Antioxidants, 8.","DOI":"10.3390\/antiox8100469"},{"key":"ref_38","doi-asserted-by":"crossref","unstructured":"Jang, S., Kim, G., Han, K., Kim, Y., Jo, J., Lee, S., Kwon, J., and Kang, B. (2022). Investigation of Genetic Factors Regulating Chlorophyll and Carotenoid Biosynthesis in Red Pepper Fruit. Front. Plant Sci., 13.","DOI":"10.3389\/fpls.2022.922963"},{"key":"ref_39","doi-asserted-by":"crossref","unstructured":"Alonso-Villegas, R., Gonz\u00e1lez-Amaro, R., Figueroa-Hern\u00e1ndez, C., and Rodr\u00edguez-Buenfil, I. (2023). The Genus Capsicum: A Review of Bioactive Properties of Its Polyphenolic and Capsaicinoid Composition. Molecules, 28.","DOI":"10.3390\/molecules28104239"},{"key":"ref_40","doi-asserted-by":"crossref","unstructured":"Guilherme, R., Aires, A., Rodrigues, N., Peres, A., and Pereira, J. (2020). Phenolics and Antioxidant Activity of Green and Red Sweet Peppers from Organic and Conventional Agriculture: A Comparative Study. Agriculture, 10.","DOI":"10.3390\/agriculture10120652"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1134\/S1021443724607262","article-title":"Relationship between Fruit Maturation, Phytochemical Content, Pungency, and Pun1 Gene Expression in Capsicum Species (Capsicum spp.)","volume":"71","author":"Arpaci","year":"2024","journal-title":"Russ. J. Plant Physiol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"5434","DOI":"10.3390\/molecules19045434","article-title":"Quantification, Antioxidant and Antimicrobial Activity of Phenolics Isolated from Different Extracts of Capsicum Frutescens (Pimenta Malagueta)","volume":"19","author":"Nascimento","year":"2014","journal-title":"Molecules"},{"key":"ref_43","doi-asserted-by":"crossref","unstructured":"Periferakis, A.-T., Periferakis, A., Periferakis, K., Caruntu, A., Badarau, I., Savulescu-Fiedler, I., Scheau, C., and Caruntu, C. (2023). Antimicrobial Properties of Capsaicin: Available Data and Future Research Perspectives. Nutrients, 15.","DOI":"10.3390\/nu15194097"},{"key":"ref_44","doi-asserted-by":"crossref","unstructured":"Oulahal, N., and Degraeve, P. (2022). Phenolic-Rich Plant Extracts with Antimicrobial Anctivity: An Alternative to Food Preservatives and Biocides?. Front. Microbiol., 12.","DOI":"10.3389\/fmicb.2021.753518"},{"key":"ref_45","unstructured":"Dereli, G., Ilhan, M., and Belwal, T. (2018). Novel Drug Targets with Traditional Herbal Medicines for Overcoming Endometriosis, Springer."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.plaphy.2016.04.055","article-title":"A Comparative Study of Mucilage and Pulp Polysaccharides from Tamarillo Fruit (Solanum betaceum Cav.)","volume":"104","author":"Nascimiento","year":"2016","journal-title":"Plant Physiol. Biochem."},{"key":"ref_47","doi-asserted-by":"crossref","unstructured":"Menezes, R., De-Souza, M., Siqueira, C., Cota, S., Vieira, E., Machado, M., Scalon, L., and Gomes, C. (2022). Antimicrobial, Antivirulence, and Antiparasitic Potential of Capsicum Chinense Jacq. Extracts and Their Isolated Compound Capsaicin. Antibiotics, 11.","DOI":"10.3390\/antibiotics11091154"},{"key":"ref_48","doi-asserted-by":"crossref","unstructured":"Sorathiya, K., Melo, A., Hogg, M., and Pintado, M. (2025). Organic Acids in Food Preservation: Exploring Synergies, Molecular Insights, and Sustainable Applications. Sustainability, 17.","DOI":"10.3390\/su17083434"},{"key":"ref_49","doi-asserted-by":"crossref","unstructured":"Ji, Q.-Y., Wang, W., Yan, H., Qu, H., Liu, Y., Qian, Y., and Gu, R. (2023). The Effect of Different Organic Acids and Their Combination on the Cell Barrier and Biofilm of Escherichia coli. Foods, 12.","DOI":"10.3390\/foods12163011"},{"key":"ref_50","doi-asserted-by":"crossref","unstructured":"Prasad, R., and Rawal, M. (2014). Efflux Pump Proteins in Antifungal Resistance. Front. Pharmacol., 5.","DOI":"10.3389\/fphar.2014.00202"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"wrae073","DOI":"10.1093\/ismejo\/wrae073","article-title":"Mechanisms and Implications of Bacterial\u2014Fungal","volume":"18","author":"Wang","year":"2024","journal-title":"ISME J."},{"key":"ref_52","doi-asserted-by":"crossref","unstructured":"Zhao, Z., Shao, S., Liu, N., Liu, Q., Jacquemyn, H., and Xing, X. (2021). Extracellular Enzyme Activities and Carbon\/Nitrogen Utilization in Mycorrhizal Fungi Isolated from Epiphytic and Terrestrial Orchids. Front. Microbiol., 12.","DOI":"10.3389\/fmicb.2021.787820"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"211","DOI":"10.4067\/s0718-58392024000200211","article-title":"Phytochemical Profile of Capsicum spp. Fruits Related to Ripeness Level, Shading and Harvest Season in the Southeast of Mexico","volume":"84","year":"2024","journal-title":"Chil. J. Agric. Res."},{"key":"ref_54","doi-asserted-by":"crossref","unstructured":"Alghamdi, M., Rathinasabapathy, T., and Komarnytsky, S. (2025). Capsaicinoid Profiles, Phenolic Content, and Antioxidant Properties of Chili Peppers Grown in Urban Settings. Int. J. Mol. Sci., 26.","DOI":"10.3390\/ijms26104916"},{"key":"ref_55","doi-asserted-by":"crossref","unstructured":"Jang, H., Choi, M., and Jang, K.-S. (2024). Comprehensive Phytochemical Profiles and Antioxidant Activity of Korean Local Cultivars of Red Chili Pepper (Capsicum annuum L.). Front. Plant Sci., 15.","DOI":"10.3389\/fpls.2024.1333035"},{"key":"ref_56","doi-asserted-by":"crossref","unstructured":"Sep\u00falveda, M., Costa, J., Cay\u00fan, Y., Gallardo, V., Barr\u00eda, E., Rigotto, G., Zeska, M., Cornejo, P., and Santos, C. (2024). Chemical Composition and Antifungal Activity of Capsicum Pepper Aqueous Extracts against Plant Pathogens and Food Spoilage Fungi. Front. Cell. Infect. Microbiol., 14.","DOI":"10.3389\/fcimb.2024.1451287"},{"key":"ref_57","doi-asserted-by":"crossref","unstructured":"Giordano, D., Facchiano, A., Minasi, P., D\u2019Agostino, N., Parisi, M., and Carbone, V. (2023). Phenolic Compounds and Capsaicinoids in Three Capsicum annuum Varieties: From Analytical Characterization to In Silico Hypotheses on Biological Activity. Molecules, 28.","DOI":"10.3390\/molecules28196772"},{"key":"ref_58","doi-asserted-by":"crossref","unstructured":"Gonz\u00e1lez-L\u00f3pez, J., Rodr\u00edguez-Moar, S., and Silvar, C. (2021). Correlation Analysis of High-Throughput Fruit Phenomics and Biochemical Profiles in Native Peppers (Capsicum spp.) from the Primary Center of Diversification. Agronomy, 11.","DOI":"10.3390\/agronomy11020262"},{"key":"ref_59","doi-asserted-by":"crossref","unstructured":"Gyawali, R., Hayek, S., and Ibrahim, S. (2015). Plant Extracts as Antimicrobials in Food Products: Types, Elsevier.","DOI":"10.1016\/B978-1-78242-034-7.00002-5"},{"key":"ref_60","doi-asserted-by":"crossref","unstructured":"Kur\u0107ubi\u0107, V., Raketi\u0107, S., Ma\u0161kovi\u0107, J., Ma\u0161kovi\u0107, P., Kur\u0107ubi\u0107, L., Heinz, V., and Tomasevic, I. (2023). Evaluation of Antimicrobial Activity of Kitaibelia Vitifolia Extract against Proven Antibiotic-Susceptible and Multidrug-Resistant (MDR) Strains of Bacteria of Clinical Origin. Plants, 12.","DOI":"10.3390\/plants12183236"},{"key":"ref_61","unstructured":"Coyago-Cruz, E. (2017). Estudio Sobre El Contenido En Carotenoides y Compuestos Fen\u00f3licos de Tomates y Flores En El Contexto de La Alimentaci\u00f3n Funcional. [Ph.D. Thesis, Universidad de Sevilla, Departamento de Ciencias Agroforestale]."}],"container-title":["Antioxidants"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-3921\/15\/6\/756\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T06:25:30Z","timestamp":1782455130000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-3921\/15\/6\/756"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,15]]},"references-count":61,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2026,6]]}},"alternative-id":["antiox15060756"],"URL":"https:\/\/doi.org\/10.3390\/antiox15060756","relation":{},"ISSN":["2076-3921"],"issn-type":[{"value":"2076-3921","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,15]]}}}