{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T12:48:58Z","timestamp":1782996538080,"version":"3.54.5"},"reference-count":24,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antioxidants"],"abstract":"<jats:p>The aim of this work is to evaluate the antioxidant activity against the radical species DPPH, the reducing capacity against Fe II ions, and the inhibitory activity on the tyrosinase enzyme of the T. triangulare. Hydromethanolic crude extract provided two fractions after the liquid\/liquid partition with chloroform. The Folin-Ciocalteu method determined the total phenolic content of the crude extract (CE) and the hydromethanolic fraction (Fraction 1), resulting in a concentration of 0.5853 g\/100 g for Fraction 1, and 0.1400 g\/100 g for the CE. Taking into account the results of the DPPH, the free radical scavenging capacity was confirmed. The formation of complexes with Fe II ions was evaluated by UV\/visible spectrometry; results showed that CE has complexing power similar to the positive control (Gingko biloba extract).The inhibitory capacity of samples against the tyrosinase enzyme was determined by the oxidation of L-DOPA, providing IC50 values of 13.3 \u03bcg\u00b7mL\u22121 (CE) and 6.6 \u03bcg\u00b7mL\u22121 (Fraction 1). The values indicate that Fraction 1 was more active and showed a higher inhibitory power on the tyrosinase enzyme than the ascorbic acid, used as positive control. The hydromethanolic extract of  T. triangulare proved to have powerful antioxidant activity and to inhibit the tyrosinase enzyme; its potential is increased after the partition with chloroform.<\/jats:p>","DOI":"10.3390\/antiox2030090","type":"journal-article","created":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T11:57:23Z","timestamp":1374062243000},"page":"90-99","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Antioxidant, Iron Chelating and Tyrosinase Inhibitory Activities of Extracts from Talinum triangulare Leach Stem"],"prefix":"10.3390","volume":"2","author":[{"given":"Ana","family":"Oliveira Amorim","sequence":"first","affiliation":[{"name":"Department of Chemistry, Institute of Exact Sciences, Universidade Federal Rural do Rio de Janeiro, Serop\u00e9dica, Rio de Janeiro 23890-000, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e1rcia","family":"Campos de Oliveira","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Institute of Exact Sciences, Universidade Federal Rural do Rio de Janeiro, Serop\u00e9dica, Rio de Janeiro 23890-000, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thiago","family":"De Azevedo Amorim","sequence":"additional","affiliation":[{"name":"Department of Botanic, Institute of Biology, Universidade Federal Rural do Rio de Janeiro, Serop\u00e9dica, Rio de Janeiro 23890-000, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aurea","family":"Echevarria","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Institute of Exact Sciences, Universidade Federal Rural do Rio de Janeiro, Serop\u00e9dica, Rio de Janeiro 23890-000, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2013,7,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1046\/j.1523-1739.2003.01315.x","article-title":"Effects of local habitat quality characteristics and landscape context on grassland butter\ufb02y diversity","volume":"17","author":"Collinge","year":"2003","journal-title":"Conserv. Biol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"317","DOI":"10.2307\/2404879","article-title":"The effects of invasion by Acacia saligna on the guild structure and regeneration capabilities of South Africa fynbos shrublands","volume":"34","author":"Holmes","year":"1997","journal-title":"J. Appl. Ecol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.foreco.2004.05.032","article-title":"Chrysanthemoides monilifera ssp. rotundata invasion alters decomposition rates in coastal areas of south-eastern Australia","volume":"198","author":"Lindsay","year":"2004","journal-title":"For. Ecol. Manag."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/j.biocon.2006.11.023","article-title":"Management regimes for a plant invader differentially impact resident communities","volume":"136","author":"Manson","year":"2007","journal-title":"Biol. Conserv."},{"key":"ref_5","unstructured":"Souza, V.C., and Lorenzi, H. (2005). Bot\u00e2nica Sistem\u00e1tica, Instituto Plantarum de Estudos da Flora Ltda."},{"key":"ref_6","first-page":"239","article-title":"Water leaf (Talinum triangulare) enhances cerebral functions in swiss albino mice","volume":"25","author":"Ofusori","year":"2008","journal-title":"J. Neurol. Sci."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"300","DOI":"10.3923\/jpt.2007.300.303","article-title":"Studies on the biochemical effects of Talinum triangulare in rat","volume":"2","author":"Ekpo","year":"2007","journal-title":"J. Pharmacol. Toxicol."},{"key":"ref_8","unstructured":"Amorim, A.P.O., Oliveira, M.C.C., and Echevarria, A. Novo \u00e1cido graxo acetiloxi substitu\u00eddo e espergulagenato isolados do caule de Talinum triangulare (Portulacaceae). Available online:http:\/\/sec.sbq.org.br\/cdrom\/31ra\/resumos\/T0064-1.pdf."},{"key":"ref_9","unstructured":"Cruz, E.M., Amorim, A.P.O., Oliveira, M.C.S., Carvalho, M.G., and Santos, M.A.V. Avalia\u00e7\u00e3o da atividade de extratos de Talinum triangulare e Sphagneticola trilobata sobre Trypanosoma cruzi. Available online:http:\/\/www.alice.cnptia.embrapa.br\/handle\/doc\/574897."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1016\/j.foodchem.2010.01.033","article-title":"Flavonoid content and antioxidant activity of vegetables from Indonesia","volume":"121","author":"Andarwulan","year":"2010","journal-title":"Food Chem."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.jbspin.2007.02.002","article-title":"Reactive oxygen species and superoxide dismutases: Role in joint diseases","volume":"74","author":"Afonso","year":"2007","journal-title":"Joint Bone Spine"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.biocel.2006.07.001","article-title":"Free radicals and antioxidants in normal physiological functions and human disease","volume":"39","author":"Valko","year":"2007","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/S0168-8278(03)00504-X","article-title":"Melatonin inhibits nuclear factor kappa Bactivation and oxidative stress and protects against thioacetamide induced liver damage in rats","volume":"40","author":"Bruck","year":"2004","journal-title":"J. Hepatol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.jep.2010.05.039","article-title":"Antioxidant, free radical scavenging, anti-inflammatory and hepatoprotective potential of the extract from Parathelypteris nipponica (Franch. et Sav.) Ching","volume":"130","author":"Fu","year":"2010","journal-title":"J. Ethnopharmacol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.intimp.2006.12.002","article-title":"Antioxidant activities of Sophora subprosrate polysaccharide in immunosuppressed mice","volume":"7","author":"Chen","year":"2007","journal-title":"Int. Immunopharmacol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.jep.2011.04.047","article-title":"Studies on the antioxidant and hepatoprotective activities of polyssaccharides from Talinum triangulare","volume":"136","author":"Zhou","year":"2011","journal-title":"J. Ethnopharmacol."},{"key":"ref_17","unstructured":"Matos, F.J.A. (2009). Introdu\u00e7\u00e3o \u00e0 Fitoqu\u00edmica Experimental, Edi\u00e7\u00f5es UFC. [3th ed.]."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1177\/1082013206070166","article-title":"Phenolic compounds and antioxidant activity of Olea europaea L fruits and leaves","volume":"12","author":"Silva","year":"2006","journal-title":"Food Sci. Technol. Int."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1002\/ptr.687","article-title":"Screening of Brazilian plant extracts for antioxidant activity by the use of DPPH free radical method","volume":"15","author":"Mensor","year":"2001","journal-title":"Phytoter. Res."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"1811","DOI":"10.1021\/jf021099r","article-title":"Utilization of Folin-Ciocalteu phenol reagent for the detection of certain nitrogen compounds","volume":"51","author":"Ikawa","year":"2003","journal-title":"J. Agric. Food Chem."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/j.foodchem.2005.05.024","article-title":"Antioxidant activities of Sechium edule (Jacq.) Swartz extracts","volume":"97","author":"Gomez","year":"2006","journal-title":"Food Chem."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1038\/nrn1537","article-title":"Iron, brain ageing and neurodegenerative disorders","volume":"5","author":"Zecca","year":"2004","journal-title":"Nat. Rev. Neurosci."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1590\/S0100-879X2004000200015","article-title":"Protection of plasmid DNA by a Ginkgo biloba extract from the effects of stannous chloride and the action on the labeling of blood elements with technetium-99m","volume":"37","author":"Moreno","year":"2004","journal-title":"Braz. J. Med. Biol. Res."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"3938","DOI":"10.1016\/S0021-9258(18)97132-2","article-title":"Potato phenolases: Purification and Properties","volume":"240","author":"Patil","year":"1965","journal-title":"J. Biol. Chem."}],"container-title":["Antioxidants"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-3921\/2\/3\/90\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T21:48:01Z","timestamp":1760219281000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-3921\/2\/3\/90"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,17]]},"references-count":24,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2013,9]]}},"alternative-id":["antiox2030090"],"URL":"https:\/\/doi.org\/10.3390\/antiox2030090","relation":{},"ISSN":["2076-3921"],"issn-type":[{"value":"2076-3921","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7,17]]}}}