{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T11:01:45Z","timestamp":1783422105662,"version":"3.54.6"},"reference-count":43,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2018,2,27]],"date-time":"2018-02-27T00:00:00Z","timestamp":1519689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antioxidants"],"abstract":"<jats:p>Guava leaf (Psidium guajava L.) extracts are used in both traditional medicine and the pharmaceutical industry. The antioxidant compounds in P. guajava leaves can have positive effects including anti-inflammatory, anti-hyperglycemic, hepatoprotective, analgesic, anti-cancer effects, as well as protecting against cardiovascular diseases. In the present study, phenolic compounds and in vitro antioxidant capacity were measured in extracts obtained with polar and non-polar solvents from leaves of two varieties of guava, Calvillo Siglo XXI and Hidrozac. The quantity of total phenolics and total flavonoids were expressed as equivalents of gallic acid and quercetin, respectively. Hydroxyl radical, 2,2\u2032-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS), 2,2-diphenyl-1-picrylhydrazyl (DPPH), and Oxygen Radical Absorbance Capacity using fluorescein (ORAC-FL) in vitro tests were used to assess the radical scavenging abilities of the extracts. The total phenolics were higher in the aqueous fraction of the variety Calvillo Siglo XXI, while in the Hidrozac variety total phenolics were higher in the acetone and chloroform fractions. Total flavonoids were higher in all fractions in the variety Calvillo Siglo XXI. Total phenolics showed a highly positive correlation for ORAC-FL, and a moderately positive correlation with hydroxyl radicals. Finally, total flavonoids showed a slightly positive correlation for ORAC-FL and hydroxyl radicals. Both varieties of guava leaf extract showed excellent antioxidant properties.<\/jats:p>","DOI":"10.3390\/antiox7030034","type":"journal-article","created":{"date-parts":[[2018,2,27]],"date-time":"2018-02-27T14:18:08Z","timestamp":1519741088000},"page":"34","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":51,"title":["Quantification of Phenolic Compounds and In Vitro Radical Scavenging Abilities with Leaf Extracts from Two Varieties of Psidium guajava L."],"prefix":"10.3390","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0142-8282","authenticated-orcid":false,"given":"Julio","family":"Camarena-Tello","sequence":"first","affiliation":[{"name":"Programa Institucional de Doctorado en Ciencias Biol\u00f3gicas, Universidad Michoacana de San Nicol\u00e1s de Hidalgo, Morelia 58240, Mich., Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9ctor","family":"Mart\u00ednez-Flores","sequence":"additional","affiliation":[{"name":"Facultad de Qu\u00edmico Farmacobiolog\u00eda, Universidad Michoacana de San Nicol\u00e1s de Hidalgo, Morelia 58240, Mich., M\u00e9xico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ma.","family":"Garnica-Romo","sequence":"additional","affiliation":[{"name":"Facultad de Ingenier\u00eda Civil, Universidad Michoacana de San Nicol\u00e1s de Hidalgo, Morelia 58240, Mich., M\u00e9xico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Padilla-Ram\u00edrez","sequence":"additional","affiliation":[{"name":"Instituto Nacional de Investigaciones Forestales, Agr\u00edcolas y Pecuarias, Centro de Investigaci\u00f3n Regional Norte-Centro, Campo Experimental Pabell\u00f3n, Pabell\u00f3n de Arteaga 20660, Aguascalientes, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfredo","family":"Saavedra-Molina","sequence":"additional","affiliation":[{"name":"Instituto de Investigaciones Qu\u00edmico Biol\u00f3gicas, Universidad Michoacana de San Nicol\u00e1s de Hidalgo, Morelia 58030, Mich., Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osvaldo","family":"Alvarez-Cortes","sequence":"additional","affiliation":[{"name":"Departamento de Bioqu\u00edmica, Instituto Tecnol\u00f3gico de Morelia, Morelia 58120, Mich., Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda","family":"Bartolom\u00e9-Camacho","sequence":"additional","affiliation":[{"name":"Facultad de Qu\u00edmico Farmacobiolog\u00eda, Universidad Michoacana de San Nicol\u00e1s de Hidalgo, Morelia 58240, Mich., M\u00e9xico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Rodiles-L\u00f3pez","sequence":"additional","affiliation":[{"name":"Facultad de Qu\u00edmico Farmacobiolog\u00eda, Universidad Michoacana de San Nicol\u00e1s de Hidalgo, Morelia 58240, Mich., M\u00e9xico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2018,2,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1007\/978-94-007-2534-8_95","article-title":"Psidium guajava","volume":"Volume 3","author":"Lim","year":"2012","journal-title":"Edible Medicinal and Non-Medicinal Plants"},{"key":"ref_2","unstructured":"SAGARPA Aumenta 8.2 por ciento producci\u00f3n de guayaba en M\u00e9xico en el \u00faltimo trienio. 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