{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T14:08:48Z","timestamp":1784902128068,"version":"3.55.0"},"reference-count":67,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2019,6,23]],"date-time":"2019-06-23T00:00:00Z","timestamp":1561248000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100011128","name":"Georgia Agricultural Experiment Stations","doi-asserted-by":"publisher","award":["HATCH #GEO00795"],"award-info":[{"award-number":["HATCH #GEO00795"]}],"id":[{"id":"10.13039\/100011128","id-type":"DOI","asserted-by":"publisher"}]},{"name":"UGA Research Foundation,","award":["Faculty Research Grant to HJP"],"award-info":[{"award-number":["Faculty Research Grant to HJP"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antioxidants"],"abstract":"<jats:p>Green tea and its catechins have been shown to ameliorate high fat diet-induced oxidative stress and hyperlipidemia. However, low bioavailability of catechins limits their therapeutic potential. Lemon juice (LJ) has been suggested to enhance the bioavailability of catechins in vitro. This study investigated the antioxidative and hypolipidemic efficacy of a single dose of green tea extract (GTE) or GTE plus LJ (GTE + LJ) in high-fat diet fed pigs. Sixteen pigs ingested a single dose of GTE (190 mg\/kg\/day) or GTE + LJ (0.75 mL\/kg\/day) mixed with low-fat (LF; 5% fat) or high-fat (HF; 22% fat) diets and blood samples were collected for 24 h. Plasma catechin level peaked at two hours, and gradually returned to baseline after six hours following the intake. The addition of LJ significantly increased plasma catechin level. The diet containing GTE did not lower plasma cholesterol and triacylglycerol (TG) concentrations, superoxide dismutase (SOD) and catalase activity, or malondialdehyde concentration in 24 h in HF-fed pigs. Addition of a single dose of LJ, however, significantly decreased plasma TG level in LF groups but did not cause further changes on any other markers compared to the GTE alone. Our findings indicate limited effect of a single meal containing GTE on plasma antioxidant enzymes, lipid profile, and lipid peroxidation in pigs and no significant synergistic\/additive action of adding LJ to GTE within 24 h in pigs. A study with a longer treatment period is warranted to further understand the potential role of GTE in reducing HF diet-induced oxidative stress and the possible synergistic role of LJ.<\/jats:p>","DOI":"10.3390\/antiox8060195","type":"journal-article","created":{"date-parts":[[2019,6,24]],"date-time":"2019-06-24T02:37:40Z","timestamp":1561343860000},"page":"195","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Effect of Acute Ingestion of Green Tea Extract and Lemon Juice on Oxidative Stress and Lipid Profile in Pigs Fed a High-Fat Diet"],"prefix":"10.3390","volume":"8","author":[{"given":"Xi","family":"Fang","sequence":"first","affiliation":[{"name":"Department of Foods and Nutrition, University of Georgia, Athens, GA 30602, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Azain","sequence":"additional","affiliation":[{"name":"Department of Animal and Dairy Science, University of Georgia, Athens, GA 30602, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2497-4582","authenticated-orcid":false,"given":"Kristi","family":"Crowe-White","sequence":"additional","affiliation":[{"name":"Department of Human Nutrition, University of Alabama, Tuscaloosa, AL 35487, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Mumaw","sequence":"additional","affiliation":[{"name":"Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janet A.","family":"Grimes","sequence":"additional","affiliation":[{"name":"Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chad","family":"Schmiedt","sequence":"additional","affiliation":[{"name":"Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Barletta","sequence":"additional","affiliation":[{"name":"Department of Large Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3550-6741","authenticated-orcid":false,"given":"Srujana","family":"Rayalam","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, Philadelphia College of Osteopathic Medicine, Suwanee, GA 30024, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hea Jin","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Foods and Nutrition, University of Georgia, Athens, GA 30602, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2019,6,23]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e330","DOI":"10.1016\/j.orcp.2013.05.004","article-title":"Increased oxidative stress in obesity: Implications for metabolic syndrome, diabetes, hypertension, dyslipidemia, atherosclerosis, and cancer","volume":"7","author":"Matsuda","year":"2013","journal-title":"Obes. Res. Clin. Pract."},{"key":"ref_2","first-page":"73","article-title":"Adherence to Mediterranean diet and 10-year incidence (2002\u20132012) of diabetes: Correlations with inflammatory and oxidative stress biomarkers in the ATTICA cohort study","volume":"32","author":"Koloverou","year":"2016","journal-title":"Diabetes"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1016\/j.metabol.2008.03.010","article-title":"Increased oxidative stress precedes the onset of high-fat diet-induced insulin resistance and obesity","volume":"57","author":"Takamura","year":"2008","journal-title":"Metabolism"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1186\/1475-2891-10-122","article-title":"Effects of acute ingestion of different fats on oxidative stress and inflammation in overweight and obese adults","volume":"10","author":"Peairs","year":"2011","journal-title":"Nutr. J."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1016\/j.bcp.2011.07.093","article-title":"Green tea catechin, epigallocatechin-3-gallate (EGCG): Mechanisms, perspectives and clinical applications","volume":"82","author":"Singh","year":"2011","journal-title":"Biochem. Pharmacol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1189\/jlb.69.5.719","article-title":"Green tea polyphenol (\u2212)-epigallocatechin-3-gallate treatment to mouse skin prevents UVB-induced infiltration of leukocytes, depletion of antigen-presenting cells, and oxidative stress","volume":"69","author":"Katiyar","year":"2001","journal-title":"J. Leukoc. Biol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0378-8741(02)00217-9","article-title":"Anti-diabetic activity of green tea polyphenols and their role in reducing oxidative stress in experimental diabetes","volume":"83","author":"Sabu","year":"2002","journal-title":"J. Ethnopharmacol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1017\/S0007114515002329","article-title":"Tea consumption and mortality of all cancers, CVD and all causes: A meta-analysis of eighteen prospective cohort studies","volume":"114","author":"Tang","year":"2015","journal-title":"Br. J. Nutr."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.tiv.2017.05.005","article-title":"Oxidative stress-induced Akt downregulation mediates green tea toxicity towards prostate cancer cells","volume":"42","author":"Posadino","year":"2017","journal-title":"Toxicol. In Vitro"},{"key":"ref_10","first-page":"201","article-title":"The Effect of Green Tea Extract on Oxidative Stress and Spatial Learning in Streptozotocin-diabetic Rats","volume":"16","author":"Sharifzadeh","year":"2017","journal-title":"Iran. J. Pharm. Res."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1080\/07315724.2016.1194236","article-title":"Short-term Effects of Green Tea on Blood Pressure, Endothelial Function, and Metabolic Profile in Obese Prehypertensive Women: A Crossover Randomized Clinical Trial","volume":"36","author":"Nogueira","year":"2017","journal-title":"J. Am. Coll. Nutr."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1139\/apnm-2016-0169","article-title":"Short-term green tea extract supplementation attenuates the postprandial blood glucose and insulin response following exercise in overweight men","volume":"41","author":"Martin","year":"2016","journal-title":"Appl. Physiol. Nutr. Metab."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"481","DOI":"10.18388\/abp.2013_2010","article-title":"Single dose of green tea extract decreases lipid digestion and absorption from a test meal in humans","volume":"60","author":"Walkowiak","year":"2013","journal-title":"Acta. Biochim. Pol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1123\/ijsnem.2013-0202","article-title":"No Effect of Short-Term Green Tea Extract Supplementation on Metabolism at Rest or During Exercise in the Fed State","volume":"24","author":"Martin","year":"2014","journal-title":"Int. J. Sport Nutr. Exerc. Metab."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1038\/oby.2010.181","article-title":"Influence of Short-Term Consumption of the Caffeine-Free, Epigallocatechin-3-Gallate Supplement, Teavigo, on Resting Metabolism and the Thermic Effect of Feeding","volume":"19","author":"Lonac","year":"2011","journal-title":"Obesity"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1123\/ijsnem.22.6.486","article-title":"Effect of a single dose of green tea polyphenols on the blood markers of exercise-induced oxidative stress in soccer players","volume":"22","author":"Jowko","year":"2012","journal-title":"Int. J. Sport Nutr. Exerc. Metab."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1111\/j.1753-4887.2011.00440.x","article-title":"Therapeutic potential of green tea in nonalcoholic fatty liver disease","volume":"70","author":"Masterjohn","year":"2012","journal-title":"Nutr. Rev."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1002\/mnfr.200700086","article-title":"Common tea formulations modulate in vitro digestive recovery of green tea catechins","volume":"51","author":"Green","year":"2007","journal-title":"Mol. Nutr. Food Res."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.foodres.2009.08.016","article-title":"Formulation with ascorbic acid and sucrose modulates catechin bioavailability from green tea","volume":"43","author":"Peters","year":"2010","journal-title":"Food Res. Int."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"169","DOI":"10.2188\/jea.JE20100084","article-title":"Frequency of citrus fruit intake is associated with the incidence of cardiovascular disease: The Jichi Medical School cohort study","volume":"21","author":"Yamada","year":"2011","journal-title":"J. Epidemiol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/s12929-015-0149-8","article-title":"5-hydroxytryptamine has an endothelium-derived hyperpolarizing factor-like effect on coronary flow in isolated rat hearts","volume":"22","author":"Chien","year":"2015","journal-title":"J. Biomed. Sci."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.jpba.2009.07.027","article-title":"Natural bioactive compounds of Citrus limon for food and health","volume":"51","author":"Moreno","year":"2010","journal-title":"J. Pharm. Biomed. Anal."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1002\/fsn3.268","article-title":"Phytochemical, antimicrobial, and antioxidant activities of different citrus juice concentrates","volume":"4","author":"Oikeh","year":"2016","journal-title":"Food Sci. Nutr."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"651","DOI":"10.3181\/0709-MR-262","article-title":"The pig as an experimental model for elucidating the mechanisms governing dietary influence on mineral absorption","volume":"233","author":"Patterson","year":"2008","journal-title":"Exp. Biol. Med."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"179","DOI":"10.7150\/ijbs.3.179","article-title":"Advances in swine biomedical model genomics","volume":"3","author":"Lunney","year":"2007","journal-title":"Int. J. Biol. Sci."},{"key":"ref_26","unstructured":"National Research Council (U.S.), and Committee on Nutrient Requirements of Swine (2012). Nutrient Requirements of Swine, National Academies Press. [11th rev. ed.]."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1093\/ajcn\/81.1.122","article-title":"Ingestion of a tea rich in catechins leads to a reduction in body fat and malondialdehyde-modified LDL in men","volume":"81","author":"Nagao","year":"2005","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"264","DOI":"10.3945\/jn.108.098293","article-title":"Green tea catechin consumption enhances exercise-induced abdominal fat loss in overweight and obese adults","volume":"139","author":"Maki","year":"2009","journal-title":"J. Nutr."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1038\/oby.2009.256","article-title":"Effects of catechin enriched green tea on body composition","volume":"18","author":"Wang","year":"2010","journal-title":"Obes. (Silver Spring)"},{"key":"ref_30","unstructured":"(2005). Estimating the Maximum Safe Starting Dose in Initial Clinical Trials for Therapeutics in Adult Healthy Volunteers."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1001\/jama.296.10.1255","article-title":"Green tea consumption and mortality due to cardiovascular disease, cancer, and all causes in Japan: The Ohsaki study","volume":"296","author":"Kuriyama","year":"2006","journal-title":"JAMA"},{"key":"ref_32","unstructured":"(2016). Food Labeling: Serving Sizes of Foods That Can Reasonably Be Consumed At One Eating Occasion; Dual-Column Labeling; Updating, Modifying, and Establishing Certain Reference Amounts Customarily Consumed; Serving Size for Breath Mints; and Technical Amendments."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1093\/chromsci\/bmw197","article-title":"A Rapid UPLC Method for Simultaneous Analysis of Caffeine and 13 Index Polyphenols in Black Tea","volume":"55","author":"Pan","year":"2017","journal-title":"J. Chromatogr. Sci."},{"key":"ref_34","first-page":"763","article-title":"Lipid profile in mice fed a high-fat diet after exogenous leptin administration","volume":"55","author":"Kalaivanisailaja","year":"2003","journal-title":"Pol. J. Pharmacol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.alcohol.2006.12.006","article-title":"Combined effects of high-fat diet and ethanol induce oxidative stress in rat liver","volume":"40","author":"Demori","year":"2006","journal-title":"Alcohol"},{"key":"ref_36","first-page":"823","article-title":"Effect of (+)-catechin hydrate on oxidative stress induced by high sucrose and high fat diet in male Wistar rats","volume":"51","author":"Mehra","year":"2013","journal-title":"Indian J. Exp. Biol."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"709","DOI":"10.3109\/1061186X.2010.551402","article-title":"Elastic liposomes as carriers for oral delivery and the brain distribution of (+)-catechin","volume":"19","author":"Huang","year":"2011","journal-title":"J. Drug Target."},{"key":"ref_38","first-page":"1025","article-title":"Pharmacokinetics of tea catechins after ingestion of green tea and (\u2212)-epigallocatechin-3-gallate by humans: Formation of different metabolites and individual variability","volume":"11","author":"Lee","year":"2002","journal-title":"Cancer Epidemiol. Biomark. Prev."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1080\/07388550290789478","article-title":"Thermodynamic aspects of biopolymer functionality in biological systems, foods, and beverages","volume":"22","author":"Tolstoguzov","year":"2002","journal-title":"Crit. Rev. Biotechnol."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0308-8146(01)00108-X","article-title":"Effect of pH on cream particle formation and solids extraction yield of black tea","volume":"74","author":"Liang","year":"2001","journal-title":"Food Chem."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1046\/j.1365-2621.2002.00589.x","article-title":"Comparative study of cream in infusions of black tea and green tea [Camellia sinensis (L.) O. Kuntze]","volume":"37","author":"Liang","year":"2002","journal-title":"Int. J. Food Sci. Technol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"2512","DOI":"10.1021\/jf971022g","article-title":"Stabilizing Effect of Ascorbic Acid on Green Tea Catechins","volume":"46","author":"Chen","year":"1998","journal-title":"J. Agric. Food Chem."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/S0022-2275(20)38520-5","article-title":"Postprandial plasma lipoprotein changes in human subjects of different ages","volume":"29","author":"Cohn","year":"1988","journal-title":"J. Lipid Res."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.jjcc.2015.12.001","article-title":"Postprandial hyperlipidemia as a potential residual risk factor","volume":"67","author":"Nakamura","year":"2016","journal-title":"J. Cardiol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/s12937-015-0009-0","article-title":"Postprandial triglyceride response in normolipidemic, hyperlipidemic and obese subjects\u2014The influence of polydextrose, a non-digestible carbohydrate","volume":"14","author":"Tiihonen","year":"2015","journal-title":"Nutr. J."},{"key":"ref_46","doi-asserted-by":"crossref","unstructured":"Metzler-Zebeli, B.U., Eberspacher, E., Grull, D., Kowalczyk, L., Molnar, T., and Zebeli, Q. (2015). Enzymatically Modified Starch Ameliorates Postprandial Serum Triglycerides and Lipid Metabolome in Growing Pigs. PLoS ONE, 10.","DOI":"10.1371\/journal.pone.0130553"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"640","DOI":"10.3945\/jn.108.103341","article-title":"Dietary green tea extract lowers plasma and hepatic triglycerides and decreases the expression of sterol regulatory element-binding protein-1c mRNA and its responsive genes in fructose-fed, ovariectomized rats","volume":"139","author":"Shrestha","year":"2009","journal-title":"J. Nutr."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1038\/ijo.2011.136","article-title":"Acute effects of epigallocatechin gallate from green tea on oxidation and tissue incorporation of dietary lipids in mice fed a high-fat diet","volume":"36","author":"Friedrich","year":"2012","journal-title":"Int. J. Obes. (Lond.)"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1079\/BJN20041379","article-title":"Effect of tea catechins on postprandial plasma lipid responses in human subjects","volume":"93","author":"Unno","year":"2005","journal-title":"Br. J. Nutr."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1017\/S0007114511002091","article-title":"Antioxidant enzymes induced by repeated intake of excess energy in the form of high-fat, high-carbohydrate meals are not sufficient to block oxidative stress in healthy lean individuals","volume":"106","author":"Lim","year":"2011","journal-title":"Br. J. Nutr."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.jsps.2016.04.011","article-title":"Serum TNF-alpha, GTH and MDA of high-fat diet-induced obesity and obesity resistant rats","volume":"24","author":"Wu","year":"2016","journal-title":"Saudi Pharm. J."},{"key":"ref_52","doi-asserted-by":"crossref","unstructured":"Montes-Nieto, R., Insenser, M., Murri, M., Fernandez-Duran, E., Ojeda-Ojeda, M., Martinez-Garcia, M.A., Luque-Ramirez, M., and Escobar-Morreale, H.F. (2017). Plasma thiobarbituric acid reactive substances (TBARS) in young adults: Obesity increases fasting levels only in men whereas glucose ingestion, and not protein or lipid intake, increases postprandial concentrations regardless of sex and obesity. Mol. Nutr. Food Res., 61.","DOI":"10.1002\/mnfr.201700425"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1139\/h11-028","article-title":"Vascular consequences of a high-fat meal in physically active and inactive adults","volume":"36","author":"Johnson","year":"2011","journal-title":"Appl. Physiol. Nutr. Metab."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1017\/S0007114507844370","article-title":"Postprandial oxidative stress is exacerbated in cigarette smokers","volume":"99","author":"Bloomer","year":"2008","journal-title":"Br. J. Nutr."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"35","DOI":"10.4137\/NMI.S12215","article-title":"Influence of acute coffee consumption on postprandial oxidative stress","volume":"6","author":"Bloomer","year":"2013","journal-title":"Nutr. Metab. Insights"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"831841","DOI":"10.1155\/2014\/831841","article-title":"Biology of ageing and role of dietary antioxidants","volume":"2014","author":"Peng","year":"2014","journal-title":"BioMed Res. Int."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1139\/apnm-2012-0222","article-title":"High-fat feeding, but not strenuous exercise, increases blood oxidative stress in trained men","volume":"38","author":"McCarthy","year":"2013","journal-title":"Appl. Physiol. Nutr. Metab."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"1913","DOI":"10.1007\/s00421-014-2912-z","article-title":"Influence of acute exercise of varying intensity and duration on postprandial oxidative stress","volume":"114","author":"Canale","year":"2014","journal-title":"Eur. J. Appl. Physiol."},{"key":"ref_59","doi-asserted-by":"crossref","unstructured":"Belinova, L., Kahleova, H., Malinska, H., Topolcan, O., Vrzalova, J., Oliyarnyk, O., Kazdova, L., Hill, M., and Pelikanova, T. (2014). Differential acute postprandial effects of processed meat and isocaloric vegan meals on the gastrointestinal hormone response in subjects suffering from type 2 diabetes and healthy controls: A randomized crossover study. PLoS ONE, 9.","DOI":"10.1371\/journal.pone.0107561"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1007\/s11357-010-9199-8","article-title":"Postprandial antioxidant effect of the Mediterranean diet supplemented with coenzyme Q10 in elderly men and women","volume":"33","author":"Caballero","year":"2011","journal-title":"AGE (Dordr)"},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1002\/mnfr.200600238","article-title":"Green tea catechins upregulate superoxide dismutase and catalase in fruit flies","volume":"51","author":"Li","year":"2007","journal-title":"Mol. Nutr. Food Res."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/1477-7827-8-59","article-title":"Seasonal variations of melatonin in ram seminal plasma are correlated to those of testosterone and antioxidant enzymes","volume":"8","author":"Casao","year":"2010","journal-title":"Reprod. Biol. Endocrinol."},{"key":"ref_63","first-page":"180","article-title":"Oxidant-antioxidant status in tissue samples of oral leukoplakia","volume":"11","author":"Srivastava","year":"2014","journal-title":"Dent. Res. J. (Isfahan)"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"181","DOI":"10.4103\/1735-3327.178210","article-title":"Evaluation of oxidant-antioxidant status in tissue samples in oral cancer: A case control study","volume":"13","author":"Srivastava","year":"2016","journal-title":"Dent. Res. J. (Isfahan)"},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1038\/oby.2008.536","article-title":"Oxidative stress in severely obese persons is greater in those with insulin resistance","volume":"17","author":"Tinahones","year":"2009","journal-title":"Obes. (Silver Spring)"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.nutres.2013.10.010","article-title":"Acute exposure to high-fat diets increases hepatic expression of genes related to cell repair and remodeling in female rats","volume":"34","author":"Miller","year":"2014","journal-title":"Nutr. Res."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"469","DOI":"10.2165\/00002018-200831060-00003","article-title":"Safety of green tea extracts: A systematic review by the US Pharmacopeia","volume":"31","author":"Sarma","year":"2008","journal-title":"Drug Saf."}],"container-title":["Antioxidants"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-3921\/8\/6\/195\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:00:43Z","timestamp":1760187643000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-3921\/8\/6\/195"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,23]]},"references-count":67,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2019,6]]}},"alternative-id":["antiox8060195"],"URL":"https:\/\/doi.org\/10.3390\/antiox8060195","relation":{},"ISSN":["2076-3921"],"issn-type":[{"value":"2076-3921","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6,23]]}}}