{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T19:57:10Z","timestamp":1778097430042,"version":"3.51.4"},"reference-count":64,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2021,5,31]],"date-time":"2021-05-31T00:00:00Z","timestamp":1622419200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Hasso Plattner Foundation","award":["LBUS-IRG-2020-06"],"award-info":[{"award-number":["LBUS-IRG-2020-06"]}]},{"DOI":"10.13039\/501100015999","name":"Universitatea &quot;Lucian Blaga&quot; din Sibiu","doi-asserted-by":"publisher","award":["LBUS-IRG-2020-06"],"award-info":[{"award-number":["LBUS-IRG-2020-06"]}],"id":[{"id":"10.13039\/501100015999","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Applied Sciences"],"abstract":"<jats:p>Grape seeds are a by-product of the wine industry. They represent 38\u201352% of grape pomace and about 5% of the weight of grapes. The main objective of this study is to establish some important characteristics of grape seeds from red varieties cultivated in Romania. The analyzed grape varieties were Cabernet Sauvignon, Merlot, Pinot noir, Burgund Mare, Cadarc\u0103, Syrah, Novac. The grape seeds were dried and ground and the following determinations were made: determination of total polyphenol content, antioxidant capacity, antiradical capacity and determination of phenolic compounds. The analyses were performed on the first day after obtaining the grape extract, on the 14th day and the 30th day. The obtained results demonstrate that all the analyzed samples have a high content of polyphenols and show antioxidant and antiradical capacity. The highest values were obtained on the first day after separation, drying, grinding and extraction of the grape seeds and began to decrease almost constantly in time, so that for 30 days from storage the values obtained could ensure good operating yields. The seeds from the Novac grape variety obtained the best results throughout the analysis period. In the case of the total polyphenol content, the average value of the three samples Novac was 394.57 mgGAE\/g dry extract and the average value of antioxidant capacity was 284.35 mgAAE\/g dry extract. The greatest antiradical capacity was presented by the seeds of the Syrah and Novac varieties. The average value of the three samples from the Syrah variety was 62.1%, and in the case of the Novac variety was 61.33%. The paper demonstrates the opportunity of superior capitalization of seeds from the seven grape varieties cultivated on the territory of Romania due to the characteristics it possesses. At present, there is a major interest of consumers in the most natural products, with a major contribution to increasing the body\u2019s immunity. The use of natural compounds in the food and pharmaceutical industry can be an important alternative.<\/jats:p>","DOI":"10.3390\/app11115124","type":"journal-article","created":{"date-parts":[[2021,5,31]],"date-time":"2021-05-31T21:42:06Z","timestamp":1622497326000},"page":"5124","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Identification and Quantification of Valuable Compounds in Red Grape Seeds"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5094-581X","authenticated-orcid":false,"given":"Ovidiu","family":"Ti\u021ba","sequence":"first","affiliation":[{"name":"Department of Agricultural Sciences and Food Engineering, Lucian Blaga University of Sibiu, Doctor Ion Ra\u021biu 7, 550012 Sibiu, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ecaterina","family":"Lengyel","sequence":"additional","affiliation":[{"name":"Department of Agricultural Sciences and Food Engineering, Lucian Blaga University of Sibiu, Doctor Ion Ra\u021biu 7, 550012 Sibiu, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3442-3760","authenticated-orcid":false,"given":"Diana Ionela","family":"Steg\u0103ru\u0219","sequence":"additional","affiliation":[{"name":"National Research and Development Institute for Cryogenics and Isotopic Technologies\u2014ICSI R\u00e2mnicu V\u00e2lcea, Uzinei 4, 240050 R\u00e2mnicu V\u00e2lcea, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petre","family":"S\u0103vescu","sequence":"additional","affiliation":[{"name":"Faculty of Agronomy, University of Craiova, Libertatii 19, 200421 Craiova, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandru Bogdan","family":"Ciubara","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Pharmacy, Dun\u0103rea de Jos University of Gala\u021bi, Alexandru Ioan Cuza 35, 800008 Gala\u021bi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6033-4737","authenticated-orcid":false,"given":"Maria Adelina","family":"Constantinescu","sequence":"additional","affiliation":[{"name":"Department of Agricultural Sciences and Food Engineering, Lucian Blaga University of Sibiu, Doctor Ion Ra\u021biu 7, 550012 Sibiu, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1235-3367","authenticated-orcid":false,"given":"Mihaela Adriana","family":"Ti\u021ba","sequence":"additional","affiliation":[{"name":"Department of Agricultural Sciences and Food Engineering, Lucian Blaga University of Sibiu, Doctor Ion Ra\u021biu 7, 550012 Sibiu, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana","family":"Ra\u021b\u0103","sequence":"additional","affiliation":[{"name":"SC ADEFARM Plus SRL, Str. Nicolae B\u0103lcescu 9, 550159 Sibiu, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anamaria","family":"Ciubara","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Pharmacy, Dun\u0103rea de Jos University of Gala\u021bi, Alexandru Ioan Cuza 35, 800008 Gala\u021bi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,5,31]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Silva, A., Silva, V., Igrejas, G., Gaiv\u00e3o, I., Aires, A., Klibi, N., Dapkevicius, M.E., Valent\u00e3o, P., Falco, V., and Poeta, P. (2021). Valorization of winemaking by-products as a novel source of antibacterial properties: New strategies to fight antibiotic resistance. Molecules, 26.","DOI":"10.3390\/molecules26082331"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Arvanitoyannis, I.S. (2008). 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