{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T15:52:43Z","timestamp":1761061963647,"version":"build-2065373602"},"reference-count":71,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2024,3,6]],"date-time":"2024-03-06T00:00:00Z","timestamp":1709683200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ARM"],"abstract":"<jats:p>Background: Patients with chronic obstructive pulmonary disease (COPD) with low skeletal muscle mass and severe airway obstruction have higher mortality risks. However, the relationship between dynamic\/static lung function (LF) and thoracic skeletal muscle measurements (SMM) remains unclear. This study explored patient characteristics (weight, BMI, exacerbations, dynamic\/static LF, sex differences in LF and SMM, and the link between LF and SMM changes. Methods: A retrospective analysis of a 12-month prospective follow-up study patients with stable COPD undergoing standardized treatment, covering mild to severe stages, was conducted. The baseline and follow-up assessments included computed tomography and body plethysmography. Results: This study included 35 patients (17 females and 18 males). This study revealed that females had more stable LF but tended to have greater declines in SMM areas and indices than males (\u22125.4% vs. \u22121.9%, respectively), despite the fact that females were younger and had higher LF and less exacerbation than males. A multivariate linear regression showed a negative association between the inspiratory capacity\/total lung capacity ratio (IC\/TLC) and muscle fat area. Conclusions: The findings suggest distinct LF and BC progression patterns between male and female patients with COPD. A low IC\/TLC ratio may predict increased muscle fat. Further studies are necessary to understand these relationships better.<\/jats:p>","DOI":"10.3390\/arm92020015","type":"journal-article","created":{"date-parts":[[2024,3,6]],"date-time":"2024-03-06T05:48:01Z","timestamp":1709704081000},"page":"123-144","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Association between the Static and Dynamic Lung Function and CT-Derived Thoracic Skeletal Muscle Measurements\u2013A Retrospective Analysis of a 12-Month Observational Follow-Up Pilot Study"],"prefix":"10.3390","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5232-4651","authenticated-orcid":false,"given":"Mia","family":"Brath","sequence":"first","affiliation":[{"name":"Respiratory Research Aalborg (Reaal), Aalborg University Hospital, 9000 Aalborg, Denmark"},{"name":"Department of Clinical Medicine, Aalborg University, 9220 Aalborg, Denmark"},{"name":"Department of Respiratory Diseases, Aalborg University Hospital, 9000 Aalborg, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sisse","family":"Alsted","sequence":"additional","affiliation":[{"name":"Department of General Medicine, North Region Hospital\u2013Hj\u00f8rring, 9800 Hj\u00f8rring, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina","family":"Sahakyan","sequence":"additional","affiliation":[{"name":"Department of Radiology, Aalborg University Hospital, 9000 Aalborg, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4176-7430","authenticated-orcid":false,"given":"Esben","family":"Mark","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine, Aalborg University, 9220 Aalborg, Denmark"},{"name":"Mech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, 9000 Aalborg, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jens","family":"Fr\u00f8kj\u00e6r","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine, Aalborg University, 9220 Aalborg, Denmark"},{"name":"Department of Radiology, Aalborg University Hospital, 9000 Aalborg, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henrik","family":"Rasmussen","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine, Aalborg University, 9220 Aalborg, Denmark"},{"name":"Department of Gastroenterology and Hepatology, Aalborg University Hospital, 9000 Aalborg, Denmark"},{"name":"Danish Nutrition Science Center, Aalborg University Hospital, 9000 Aalborg, Denmark"},{"name":"Center for Nutrition and Intestinal Failure, Aalborg University Hospital, 9000 Aalborg, Denmark"},{"name":"Department of Dietetic and Nutritional Research, Copenhagen University Hospitals, Herlev and Gentofte Hospitals, 2730 Herlev, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lasse","family":"\u00d8stergaard","sequence":"additional","affiliation":[{"name":"Medical Informatics Group, Department of Health Science and Technology, Aalborg University, 9220 Aalborg, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rasmus","family":"Christensen","sequence":"additional","affiliation":[{"name":"Department of Radiology, Aalborg University Hospital, 9000 Aalborg, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1975-3654","authenticated-orcid":false,"given":"Ulla","family":"Weinreich","sequence":"additional","affiliation":[{"name":"Respiratory Research Aalborg (Reaal), Aalborg University Hospital, 9000 Aalborg, Denmark"},{"name":"Department of Clinical Medicine, Aalborg University, 9220 Aalborg, Denmark"},{"name":"Department of Respiratory Diseases, Aalborg University Hospital, 9000 Aalborg, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,3,6]]},"reference":[{"key":"ref_1","unstructured":"(2024, February 12). 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