{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T08:25:49Z","timestamp":1780734349462,"version":"3.54.1"},"reference-count":17,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T00:00:00Z","timestamp":1750118400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000897","name":"Cystic Fibrosis Foundation","doi-asserted-by":"publisher","award":["BARTLE19D0"],"award-info":[{"award-number":["BARTLE19D0"]}],"id":[{"id":"10.13039\/100000897","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ARM"],"abstract":"<jats:p>Poor sleep quality and excessive daytime sleepiness are commonly reported by individuals with cystic fibrosis. The potential impact of comorbid sleep-disordered breathing (SDB), particularly obstructive sleep apnea (OSA), has not been extensively studied in the CF population. At present, there are no specific recommendations available to help clinicians identify patients with CF who are at increased risk of sleep disorders. Home sleep apnea testing using a validated peripheral arterial tonometry (PAT) device may offer an accurate diagnosis of OSA in a more convenient and low-cost method than in-lab polysomnography. In this single-center study of 19 adults with CF, we found an increased prevalence of OSA among individuals with CF compared to general population estimates. Although associations with an FEV &lt; 70% predicted and a modified Mallampati score \u2265 3 were observed, these odds ratios did not reach statistical significance, likely reflecting limited power in this small pilot sample. There was no association found between the self-reported presence of nocturnal cough or snoring and OSA. We also found no association between OSA and abnormal scores on commonly used, validated sleep questionnaires, suggesting that CF-specific scales may be needed for effective screening in the CF clinic.<\/jats:p>","DOI":"10.3390\/arm93030020","type":"journal-article","created":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T03:37:07Z","timestamp":1750131427000},"page":"20","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Evaluating Obstructive Sleep Apnea Utilizing Arterial Tonometry in Individuals with Cystic Fibrosis"],"prefix":"10.3390","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-2905-134X","authenticated-orcid":false,"given":"Michelle","family":"Chiu","sequence":"first","affiliation":[{"name":"Department of Pediatric Pulmonology, Mass General Brigham for Children, Boston, MA 02114, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9043-6697","authenticated-orcid":false,"given":"Bethany","family":"Bartley","sequence":"additional","affiliation":[{"name":"Department of Sleep Medicine, Brigham and Women\u2019s Hospital, Boston, MA 02115, USA"},{"name":"Division of Sleep Medicine, Harvard Medical School, Boston, MA 02115, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Gootkind","sequence":"additional","affiliation":[{"name":"Department of Pediatric Pulmonology, Mass General Brigham for Children, Boston, MA 02114, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salma","family":"Batool-Anwar","sequence":"additional","affiliation":[{"name":"Department of Sleep Medicine, Brigham and Women\u2019s Hospital, Boston, MA 02115, USA"},{"name":"Division of Sleep Medicine, Harvard Medical School, Boston, MA 02115, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald G.","family":"Keamy","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head & Neck Surgery, Mass Eye & Ear, Boston, MA 02114, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas Bernard","family":"Kinane","sequence":"additional","affiliation":[{"name":"Department of Pediatric Pulmonology, Mass General Brigham for Children, Boston, MA 02114, USA"},{"name":"Division of Sleep Medicine, Harvard Medical School, Boston, MA 02115, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lael M.","family":"Yonker","sequence":"additional","affiliation":[{"name":"Department of Pediatric Pulmonology, Mass General Brigham for Children, Boston, MA 02114, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2671-985X","authenticated-orcid":false,"given":"Kevin S.","family":"Gipson","sequence":"additional","affiliation":[{"name":"Department of Pediatric Pulmonology, Mass General Brigham for Children, Boston, MA 02114, USA"},{"name":"Division of Sleep Medicine, Harvard Medical School, Boston, MA 02115, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,6,17]]},"reference":[{"key":"ref_1","unstructured":"Cystic Fibrosis Foundation Patient Registry (2021). 2021 Annual Data Report, National Institutes of Health."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S2213-2600(19)30337-6","article-title":"The future of cystic fibrosis care: A global perspective","volume":"8","author":"Bell","year":"2020","journal-title":"Lancet Respir. 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