{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T15:11:22Z","timestamp":1785424282040,"version":"3.56.0"},"reference-count":32,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T00:00:00Z","timestamp":1785110400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecn\u00f3logico","award":["#401633\/2023-3"],"award-info":[{"award-number":["#401633\/2023-3"]}]},{"award":["#401633\/2023-3"],"award-info":[{"award-number":["#401633\/2023-3"]}],"id":[{"id":"https:\/\/ror.org\/03swz6y49","id-type":"ROR","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004586","name":"Funda\u00e7\u00e3o Carlos Chagas Filho de Amparo \u00e0 Pesquisa do Estado do Rio de Janeiro","doi-asserted-by":"publisher","award":["#E-26\/200.037\/2026"],"award-info":[{"award-number":["#E-26\/200.037\/2026"]}],"id":[{"id":"10.13039\/501100004586","id-type":"DOI","asserted-by":"publisher"}]},{"award":["#E-26\/200.037\/2026"],"award-info":[{"award-number":["#E-26\/200.037\/2026"]}],"id":[{"id":"https:\/\/ror.org\/03kk0s825","id-type":"ROR","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"crossref","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"crossref"}]},{"award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"https:\/\/ror.org\/00x0ma614","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Adv. Respir. Med.","ARM"],"abstract":"<jats:p>Although poverty and tuberculosis are insidiously linked, knowledge of the relationship between social determinants of health (SDoHs) and post-tuberculosis lung disease (PTLD) is limited. This study aimed to analyze the association between physical function, pulmonary function, and SDoHs in individuals with PTLD (iwPTLD), considering the impact of social inequalities on physical performance. This cross-sectional study collected social data from 69 iwPTLDs using a standardized assessment form. The patients underwent pulmonary function testing via spirometry and body plethysmography, as well as respiratory muscle strength and quadriceps muscle strength (QMS) testing. They also completed the six-minute step test (6MST). The median value of steps climbed by participants on the 6MST was 88 (57\u2013117), corresponding to 50.1% (34.9\u201373.2) of the predicted value. The mean QMS was 28.7 \u00b1 11.9 kgf, with 11 participants (17.4%) showing QMS below the cutoff point. Spirometry revealed normal, obstructive, restrictive, and mixed patterns in 19 (27.5%), 20 (29%), 18 (26.1%), and 12 (17.4%) of the participants, respectively. Performance on the 6MST showed no statistically significant association with SDoHs. QMS showed a statistically significant association with treated sewage (W = 84, p = 0.026). Forced expiratory volume in one second showed significant correlations with education level (\u03c1 = 0.248, p = 0.040), social protection (W = 207, p = 0.050, r = 0.238), and treated water (W = 24.5, p = 0.029, r = 0.264). Maximum inspiratory pressure showed significant correlations with education level (\u03c1 = 0.246, p = 0.042) and treated water (W = 20, p = 0.021, r = 0.280). The regression model for 6MST and QMS performance showed that 12% and 45% of the variability was explained by the studied variables, respectively. In iwPTLD, impairments in physical function and damage to lung function are weakly associated with the deterioration of SDoHs. While this relationship is weak, it should not be ignored because it may operate through indirect pathways.<\/jats:p>","DOI":"10.3390\/arm94040052","type":"journal-article","created":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T08:15:56Z","timestamp":1785140156000},"page":"52","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Association Between Physical Function, Pulmonary Function, and Social Determinants of Health in Individuals with Post-Tuberculosis Lung Disease"],"prefix":"10.3390","volume":"94","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-5438-1552","authenticated-orcid":false,"given":"Nielza Moreira","family":"de Souza","sequence":"first","affiliation":[{"name":"Rehabilitation Sciences Post-Graduation Program, Augusto Motta University Center (UNISUAM), Rua Dona Isabel, 94, Bonsucesso, Rio de Janeiro 21032-060, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-8417-7383","authenticated-orcid":false,"given":"Pedro Henrique Perpetuo","family":"de Lima Silva","sequence":"additional","affiliation":[{"name":"Rehabilitation Sciences Post-Graduation Program, Augusto Motta University Center (UNISUAM), Rua Dona Isabel, 94, Bonsucesso, Rio de Janeiro 21032-060, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-3380-130X","authenticated-orcid":false,"given":"Estephane Ramos","family":"de Souza Penna","sequence":"additional","affiliation":[{"name":"Faculty of Physiotherapy, Augusto Motta University Center (UNISUAM), Av. Paris, 84, Bonsucesso, Rio de Janeiro 21041-020, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-1013-5585","authenticated-orcid":false,"given":"Amanda Oliveira","family":"dos Anjos","sequence":"additional","affiliation":[{"name":"Faculty of Physiotherapy, Augusto Motta University Center (UNISUAM), Av. Paris, 84, Bonsucesso, Rio de Janeiro 21041-020, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0262-0006","authenticated-orcid":false,"given":"Al\u00edcia Sales","family":"Carneiro","sequence":"additional","affiliation":[{"name":"Department of Pulmonology, Pedro Ernesto University Hospital, Universidade do Estado do Rio de Janeiro (UERJ), Boulevard 28 de Setembro, 77, Vila Isabel, Rio de Janeiro 20551-030, Brazil"},{"name":"Postgraduate Program in Medical Sciences, School of Medical Sciences, Universidade do Estado do Rio de Janeiro (UERJ), Avenida Professor Manoel de Abreu, 444, 2\u00ba Andar, Vila Isabel, Rio de Janeiro 20550-170, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0831-8585","authenticated-orcid":false,"given":"Walter","family":"Costa","sequence":"additional","affiliation":[{"name":"Department of Pulmonology, Pedro Ernesto University Hospital, Universidade do Estado do Rio de Janeiro (UERJ), Boulevard 28 de Setembro, 77, Vila Isabel, Rio de Janeiro 20551-030, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0255-1696","authenticated-orcid":false,"given":"Bruna Cuoco","family":"Provenzano","sequence":"additional","affiliation":[{"name":"Department of Pulmonology, Pedro Ernesto University Hospital, Universidade do Estado do Rio de Janeiro (UERJ), Boulevard 28 de Setembro, 77, Vila Isabel, Rio de Janeiro 20551-030, Brazil"},{"name":"Postgraduate Program in Medical Sciences, School of Medical Sciences, Universidade do Estado do Rio de Janeiro (UERJ), Avenida Professor Manoel de Abreu, 444, 2\u00ba Andar, Vila Isabel, Rio de Janeiro 20550-170, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5226-4372","authenticated-orcid":false,"given":"Ana Paula","family":"Santos","sequence":"additional","affiliation":[{"name":"Department of Pulmonology, Pedro Ernesto University Hospital, Universidade do Estado do Rio de Janeiro (UERJ), Boulevard 28 de Setembro, 77, Vila Isabel, Rio de Janeiro 20551-030, Brazil"},{"name":"Postgraduate Program in Medical Sciences, School of Medical Sciences, Universidade do Estado do Rio de Janeiro (UERJ), Avenida Professor Manoel de Abreu, 444, 2\u00ba Andar, Vila Isabel, Rio de Janeiro 20550-170, Brazil"},{"name":"Medical School and Institute of Thorax Diseases, Universidade Federal do Rio de Janeiro (UFRJ), Rua Prof. Rodolpho Paulo Rocco, 255, Sala 01D 58\/60, Cidade Universit\u00e1ria, Rio de Janeiro 21941-913, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8598-4878","authenticated-orcid":false,"given":"Agnaldo Jos\u00e9","family":"Lopes","sequence":"additional","affiliation":[{"name":"Rehabilitation Sciences Post-Graduation Program, Augusto Motta University Center (UNISUAM), Rua Dona Isabel, 94, Bonsucesso, Rio de Janeiro 21032-060, Brazil"},{"name":"Department of Pulmonology, Pedro Ernesto University Hospital, Universidade do Estado do Rio de Janeiro (UERJ), Boulevard 28 de Setembro, 77, Vila Isabel, Rio de Janeiro 20551-030, Brazil"},{"name":"Postgraduate Program in Medical Sciences, School of Medical Sciences, Universidade do Estado do Rio de Janeiro (UERJ), Avenida Professor Manoel de Abreu, 444, 2\u00ba Andar, Vila Isabel, Rio de Janeiro 20550-170, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,7,27]]},"reference":[{"key":"ref_1","first-page":"e20230055","article-title":"Diagnosis and management of post-tuberculosis lung disease","volume":"49","author":"Silva","year":"2023","journal-title":"J. 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