{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T13:38:13Z","timestamp":1767879493041,"version":"3.49.0"},"reference-count":18,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2020,11,14]],"date-time":"2020-11-14T00:00:00Z","timestamp":1605312000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Audiology Research"],"abstract":"<jats:p>Introduction\u2014Although auditory brainstem response (ABR) testing is among the most frequently used investigations in pediatric audiology and it often requires sedation or general anesthesia. In recent years, melatonin has been successfully used as an alternative way of inducing sleep, particularly in children undergoing magnetic resonance imaging (MRI) or electroencephalography (EEG). Purpose\u2014To assess the effectiveness of orally administered melatonin as an alternative to sedation or general anesthesia during ABR testing. Method\u2014In total, 33 children with suspected hearing loss underwent ABR tests in melatonin-induced sleep. Each patient received an initial dose of 5 mg, which was re-administered in case of failure to obtain sleep. Click-induced ABR tests were performed on both ears. Results\u2014ABR tests were successfully performed in 72.7% of the patients. The average total length of time needed to obtain sleep and complete the ABR testing was 45 min. There was no significant difference between the patients who completed the examination and those who did not in terms of age or psychomotor development. There was a statistically significant association between receiving a maintenance dose and successful completion of the test (p &lt; 0.001). There was also a significant connection between the degree of hearing loss and the success rate of the ABR tests (p &lt; 0.001). Conclusions\u2014Melatonin-induced sleep is a good and safer alternative to anesthesia to perform ABR testing in young children. It is easily administered, tolerated by the patients, and accepted by parents.<\/jats:p>","DOI":"10.3390\/audiolres10020009","type":"journal-article","created":{"date-parts":[[2020,11,16]],"date-time":"2020-11-16T22:53:52Z","timestamp":1605567232000},"page":"50-54","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Efficiency of Melatonin as a Sedative for Auditory Brainstem Response in Children"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9980-2254","authenticated-orcid":false,"given":"Anass","family":"Chaouki","sequence":"first","affiliation":[{"name":"Faculty of Medicine of Casablanca, Casablanca 20 000, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zineb","family":"El Krimi","sequence":"additional","affiliation":[{"name":"Faculty of Medicine of Casablanca, Casablanca 20 000, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amine","family":"Mkhatri","sequence":"additional","affiliation":[{"name":"Faculty of Medicine of Casablanca, Casablanca 20 000, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oukessou","family":"Youssef","sequence":"additional","affiliation":[{"name":"Faculty of Medicine of Casablanca, Casablanca 20 000, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sami","family":"Rouadi","sequence":"additional","affiliation":[{"name":"Faculty of Medicine of Casablanca, Casablanca 20 000, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reda","family":"Abada","sequence":"additional","affiliation":[{"name":"Faculty of Medicine of Casablanca, Casablanca 20 000, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Roubal","sequence":"additional","affiliation":[{"name":"Faculty of Medicine of Casablanca, Casablanca 20 000, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Mahtar","sequence":"additional","affiliation":[{"name":"Faculty of Medicine of Casablanca, Casablanca 20 000, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2020,11,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1016\/j.ijporl.2005.04.011","article-title":"Comparison of propofol with propofol\u2013ketamine combination in pediatric patients undergoing auditory brainstem response testing","volume":"69","author":"Akin","year":"2005","journal-title":"Int. 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