{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T04:53:32Z","timestamp":1781931212091,"version":"3.54.5"},"reference-count":40,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2022,6,21]],"date-time":"2022-06-21T00:00:00Z","timestamp":1655769600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Audiology Research"],"abstract":"<jats:p>The Weber tuning fork test is a standard otologic examination tool in patients with unilateral hearing loss. Sound should typically lateralize to the contralateral side in unilateral sensorineural hearing loss. The observation that the Weber test does not lateralize in some patients with longstanding unilateral deafness has been previously described but remains poorly understood. In the present study, we conducted a retrospective analysis of the medical records of patients with unilateral profound hearing loss (single-sided deafness or asymmetric hearing loss) for at least ten years. In this patient cohort, childhood-onset unilateral profound hearing loss was significantly associated with the lack of lateralization of the Weber tuning fork test (Fisher\u2019s exact test, p &lt; 0.05) and the absence of tinnitus in the affected ear (Fisher\u2019s exact test, p &lt; 0.001). The findings may imply a central adaptation process due to chronic unilateral auditory deprivation starting before the critical period of auditory maturation. This notion may partially explain the poor outcome of adult cochlear implantation in longstanding single-sided deafness. The findings may suggest a role for the Weber test as a simple, quick, and economical tool for screening poor cochlear implant candidates, thus potentially supporting the decision-making and counseling of patients with longstanding single-sided deafness.<\/jats:p>","DOI":"10.3390\/audiolres12040036","type":"journal-article","created":{"date-parts":[[2022,6,21]],"date-time":"2022-06-21T04:39:55Z","timestamp":1655786395000},"page":"347-356","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Lateralization Pattern of the Weber Tuning Fork Test in Longstanding Unilateral Profound Hearing Loss: Implications for Cochlear Implantation"],"prefix":"10.3390","volume":"12","author":[{"given":"Mohamed","family":"Bassiouni","sequence":"first","affiliation":[{"name":"Corporate Member of Freie Universit\u00e4t Berlin, Berlin Institute of Health, Charit\u00e9platz 1, Humboldt-Universit\u00e4t zu Berlin, 10117 Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophia Marie","family":"H\u00e4u\u00dfler","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, University Medical Center Hamburg-Eppendorf, Martinistra\u00dfe 52, 20246 Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Gr\u00e4bel","sequence":"additional","affiliation":[{"name":"Corporate Member of Freie Universit\u00e4t Berlin, Berlin Institute of Health, Charit\u00e9platz 1, Humboldt-Universit\u00e4t zu Berlin, 10117 Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9292-6606","authenticated-orcid":false,"given":"Agnieszka J.","family":"Szczepek","sequence":"additional","affiliation":[{"name":"Corporate Member of Freie Universit\u00e4t Berlin, Berlin Institute of Health, Charit\u00e9platz 1, Humboldt-Universit\u00e4t zu Berlin, 10117 Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heidi","family":"Olze","sequence":"additional","affiliation":[{"name":"Corporate Member of Freie Universit\u00e4t Berlin, Berlin Institute of Health, Charit\u00e9platz 1, Humboldt-Universit\u00e4t zu Berlin, 10117 Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,6,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"395","DOI":"10.3109\/00016487009123384","article-title":"Lateralization of bone conduction into the better ear in conductive deafness. 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