{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T11:11:00Z","timestamp":1762081860168,"version":"build-2065373602"},"reference-count":29,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2022,12,21]],"date-time":"2022-12-21T00:00:00Z","timestamp":1671580800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Audiology Research"],"abstract":"<jats:p>Background: Cochlear implantation (CI) following endoscopic transcanal infrapromontorial vestibular schwannoma (VS) dissection is a feasible intervention in intracanalicular VS, with minimal extension into the cerebellopontine angle, but no audiologic results have ever been reported in the literature. Methods: From 2015 to 2021 in the Otorhynolaryngology Departments of Modena and Verona, three patients underwent this intervention. All were suffering from sporadic left-sided intracanalicular Koos I VS. Intraoperative electrically evoked auditory brainstem responses and electrophysiological measurements were performed before and after the placement of the electrode array, respectively. Since device activation one month after the surgery, each patient was followed up with audiometric tests, data logging, electrode impedance measurements and neural response telemetry performed at each scheduled fitting session at 15 days and 3, 6, 12 and 24 months. Results: Only in patient No. 3, an auditory benefit was observed and still evident even 36 months after activation. Impedances increased progressively in patient No. 1 and a benefit was never reported. Patient No. 2 left the follow-up for worsening comorbidities. Conclusions: CI following transcanal infrapromontorial VS resection is a beneficial intervention. The residual cochlear nerve after the tumour dissection and the course of electrophysiological measurements in the postoperative period were the main predictive factors for audiological outcomes.<\/jats:p>","DOI":"10.3390\/audiolres13010001","type":"journal-article","created":{"date-parts":[[2022,12,21]],"date-time":"2022-12-21T06:42:57Z","timestamp":1671604977000},"page":"1-11","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Cochlear Implantation Following Transcanal Infrapromontorial Approach for Vestibular Schwannoma: A Case Series"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9260-1003","authenticated-orcid":false,"given":"Virginia","family":"Dallari","sequence":"first","affiliation":[{"name":"Section of Ear, Nose and Throat (ENT), Department of Surgical Sciences, Dentistry, Gynaecology and Paediatrics, Borgo Roma Hospital, University of Verona, 37134 Verona, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0688-5770","authenticated-orcid":false,"given":"Enrico","family":"Apa","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences for Children and Adults, Otorhinolaryngology Unit, Azienda Ospedaliero-Universitaria of Modena, University of Modena and Reggio Emilia, 41125 Modena, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniele","family":"Monzani","sequence":"additional","affiliation":[{"name":"Section of Ear, Nose and Throat (ENT), Department of Surgical Sciences, Dentistry, Gynaecology and Paediatrics, Borgo Roma Hospital, University of Verona, 37134 Verona, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabetta","family":"Genovese","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences for Children and Adults, Otorhinolaryngology Unit, Azienda Ospedaliero-Universitaria of Modena, University of Modena and Reggio Emilia, 41125 Modena, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniele","family":"Marchioni","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences for Children and Adults, Otorhinolaryngology Unit, Azienda Ospedaliero-Universitaria of Modena, University of Modena and Reggio Emilia, 41125 Modena, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4814-5212","authenticated-orcid":false,"given":"Davide","family":"Soloperto","sequence":"additional","affiliation":[{"name":"Section of Ear, Nose and Throat (ENT), Department of Surgical Sciences, Dentistry, Gynaecology and Paediatrics, Borgo Roma Hospital, University of Verona, 37134 Verona, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3880-4998","authenticated-orcid":false,"given":"Luca","family":"Sacchetto","sequence":"additional","affiliation":[{"name":"Section of Ear, Nose and Throat (ENT), Department of Surgical Sciences, Dentistry, Gynaecology and Paediatrics, Borgo Roma Hospital, University of Verona, 37134 Verona, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"E2312","DOI":"10.1002\/lary.29436","article-title":"Early Outcomes of Simultaneous Translabyrinthine Resection and Cochlear Implantation","volume":"131","author":"Conway","year":"2021","journal-title":"Laryngoscope"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1007\/s00405-012-2137-x","article-title":"From external to internal auditory canal: Surgical anatomy by an exclusive endoscopic approach","volume":"270","author":"Marchioni","year":"2013","journal-title":"Eur. Arch. Otorhinolaryngol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1093\/neuros\/nyy409","article-title":"Koos Classification of Vestibular Schwannomas: A Reliability Study","volume":"85","author":"Erickson","year":"2019","journal-title":"Neurosurgery"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"2862","DOI":"10.1002\/lary.24072","article-title":"Cochlear schwannoma removed through the external auditory canal by a transcanal exclusive endoscopic technique","volume":"123","author":"Presutti","year":"2013","journal-title":"Laryngoscope"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1016\/j.otc.2016.05.014","article-title":"The Fully Endoscopic Acoustic Neuroma Surgery","volume":"49","author":"Marchioni","year":"2016","journal-title":"Otolaryngol. Clin. N. Am."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"2608","DOI":"10.1002\/lary.26559","article-title":"Expanded transcanal transpromontorial approach to the internal auditory canal: Pilot clinical experience","volume":"127","author":"Presutti","year":"2017","journal-title":"Laryngoscope"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1177\/0194599818756592","article-title":"Expanded Transcanal Transpromontorial Approach: A Novel Surgical Technique for Cerebellopontine Angle Vestibular Schwannoma Removal","volume":"158","author":"Marchioni","year":"2018","journal-title":"Otolaryngol. Head Neck Surg."},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Molinari, G., Calvaruso, F., Presutti, L., Marchioni, D., Alicandri-Ciufelli, M., Friso, F., Fernandez, I.J., Francoli, P., and Di Maro, F. (2022). Vestibular schwannoma removal through expanded transcanal transpromontorial approach: A multicentric experience. Eur. Arch. Otorhinolaryngol.","DOI":"10.1007\/s00405-022-07682-3"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1097\/MAO.0000000000001980","article-title":"Hearing Restoration During Vestibular Schwannoma Surgery With Transcanal Approach: Anatomical and Functional Preliminary Report","volume":"39","author":"Marchioni","year":"2018","journal-title":"Otol. Neurotol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1007\/s00405-020-05821-2","article-title":"Transcanal infrapromontorial approach for internal auditory canal surgery and cochlear implantation","volume":"277","author":"Rubini","year":"2020","journal-title":"Eur. Arch. Otorhinolaryngol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"103486","DOI":"10.1016\/j.amjoto.2022.103486","article-title":"Expanded transcanal transpromontorial approach for vestibular schwannoma","volume":"43","author":"Marchioni","year":"2022","journal-title":"Am. J. Otolaryngol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1097\/MAO.0000000000002747","article-title":"Simultaneous Vestibular Schwannoma Resection and Cochlear Implantation Using Electrically Evoked Auditory Brainstem Response Audiometry for Decision-making","volume":"41","author":"Dahm","year":"2020","journal-title":"Otol. Neurotol."},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Clark, G. (2003). Neurobiology. COCHLEAR IMPLANTS Fundamentals and Applications, Springer. [1st ed.].","DOI":"10.1007\/b97263"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1097\/MAO.0b013e31827c9d71","article-title":"How well do cochlear implant intraoperative impedance measures predict postoperative electrode function?","volume":"34","author":"Goehring","year":"2013","journal-title":"Otol. Neurotol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1097\/MAO.0b013e3182423175","article-title":"An evidence-based algorithm for intraoperative monitoring during cochlear implantation","volume":"33","author":"Cosetti","year":"2012","journal-title":"Otol. Neurotol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1097\/PRS.0000000000000905","article-title":"Facial nerve grading instruments: Systematic review of the literature and suggestion for uniformity","volume":"135","author":"Fattah","year":"2015","journal-title":"Plast. Reconstr. Surg."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.ijsu.2020.11.005","article-title":"The PROCESS 2020 Guideline: Updating Consensus Preferred Reporting Of CasESeries in Surgery (PROCESS) Guidelines","volume":"84","author":"Agha","year":"2020","journal-title":"Int. J. Surg."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"American Academy of Otolaryngology-Head and Neck Surgery Foundation, INC (1995). Committee on Hearing and Equilibrium guidelines for the evaluation of hearing preservation in acoustic neuroma (vestibular schwannoma). Otolaryngol. Head Neck Surg., 113, 179\u2013180.","DOI":"10.1016\/S0194-5998(95)70101-X"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/B978-0-444-63437-5.00009-1","article-title":"The caloric irrigation test","volume":"137","author":"Shepard","year":"2016","journal-title":"Handb. Clin. Neurol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1097\/MAO.0000000000002602","article-title":"Hearing Preservation Outcomes and Prognostic Factors in Acoustic Neuroma Surgery: Predicting Cutoffs","volume":"41","author":"Zanoletti","year":"2020","journal-title":"Otol. Neurotol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1097\/MAO.0000000000003258","article-title":"Simultaneous Cochlear Implantation After Translabyrinthine Vestibular Schwannoma Resection: A Report of 41 Cases","volume":"42","author":"Sanna","year":"2021","journal-title":"Otol. Neurotol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"4709","DOI":"10.1007\/s00405-021-07243-0","article-title":"Cochlear implant in vestibular schwannomas: Long-term outcomes and critical analysis of indications","volume":"279","author":"Sorrentino","year":"2022","journal-title":"Eur. Arch. Otorhinolaryngol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1159\/000448583","article-title":"Vestibular Schwannoma Resection with Ipsilateral Simultaneous Cochlear Implantation in Patients with Normal Contralateral Hearing","volume":"21","author":"Sanna","year":"2016","journal-title":"Audiol. Neurootol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1097\/MAO.0000000000002784","article-title":"Cochlear Implant Outcomes Following Vestibular Schwannoma Resection: Systematic Review","volume":"41","author":"Wick","year":"2020","journal-title":"Otol. Neurotol."},{"key":"ref_25","first-page":"1","article-title":"Is the Intraoperative Morphology of the Cochlear nerve a Good Predictor of the Results of Simultaneous Ipsilateral Cochlear Implantation in Vestibular Schwannoma Surgery?","volume":"19","author":"Marchioni","year":"2022","journal-title":"J. Laryngol. Otol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"886171","DOI":"10.3389\/fneur.2022.886171","article-title":"Cochlear Implant Electrode Impedance as Potential Biomarker for Residual Hearing","volume":"13","author":"Wimmer","year":"2022","journal-title":"Front. Neurol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1795","DOI":"10.1007\/s00405-021-06855-w","article-title":"Quality of life in vestibular schwannoma: A comparison of three surgical techniques","volume":"279","author":"Lucidi","year":"2022","journal-title":"Eur. Arch. Otorhinolaryngol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"382","DOI":"10.5152\/iao.2022.21541","article-title":"Cochlear Implantation for Patients with a Vestibular Schwannoma: Effect on Tinnitus Handicap","volume":"18","author":"West","year":"2022","journal-title":"J. Int. Adv. Otol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1093\/neuonc\/noz153","article-title":"EANO guideline on the diagnosis and treatment of vestibular schwannoma","volume":"22","author":"Goldbrunner","year":"2020","journal-title":"Neuro Oncol."}],"container-title":["Audiology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2039-4349\/13\/1\/1\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:45:26Z","timestamp":1760147126000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2039-4349\/13\/1\/1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,21]]},"references-count":29,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,2]]}},"alternative-id":["audiolres13010001"],"URL":"https:\/\/doi.org\/10.3390\/audiolres13010001","relation":{},"ISSN":["2039-4349"],"issn-type":[{"type":"electronic","value":"2039-4349"}],"subject":[],"published":{"date-parts":[[2022,12,21]]}}}