{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T00:47:17Z","timestamp":1793407637375,"version":"4.5.0"},"reference-count":41,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T00:00:00Z","timestamp":1737331200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Audiology Research"],"abstract":"<jats:p>Aim: The aim of this study was to assess the subjective experiences of adults with different cochlear implant (CI) configurations\u2014unilateral cochlear implant (UCI), bilateral cochlear implant (BCI), and bimodal stimulation (BM)\u2014focusing on their perception of speech in quiet and noisy environments, music, environmental sounds, people\u2019s voices and tinnitus. Methods: A cross-sectional survey of 130 adults who had undergone UCI, BCI, or BM was conducted. Participants completed a six-item online questionnaire, assessing difficulty levels and psychological impact across auditory domains, with responses measured on a 10-point scale. Statistical analyses were performed to compare the subjective experiences of the three groups. Results: Patients reported that understanding speech in noise and tinnitus perception were their main concerns. BCI users experienced fewer difficulties with understanding speech in both quiet (p &lt; 0.001) and noisy (p = 0.008) environments and with perceiving non-vocal sounds (p = 0.038) compared to UCI and BM users; no significant differences were found for music perception (p = 0.099), tinnitus perception (p = 0.397), or voice naturalness (p = 0.157). BCI users also reported less annoyance in quiet (p = 0.004) and noisy (p = 0.047) environments, and in the perception of voices (p = 0.009) and non-vocal sounds (p = 0.019). Tinnitus-related psychological impact showed no significant differences between groups (p = 0.090). Conclusions: Although speech perception in noise and tinnitus remain major problems for CI users, the results of our study suggest that bilateral cochlear implantation offers significant subjective advantages over unilateral implantation and bimodal stimulation in adults, particularly in difficult listening environments.<\/jats:p>","DOI":"10.3390\/audiolres15010006","type":"journal-article","created":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T10:32:15Z","timestamp":1737369135000},"page":"6","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Unilateral Versus Bilateral Cochlear Implants in Adults: A Cross-Sectional Questionnaire Study Across Multiple Hearing Domains"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-4236-4539","authenticated-orcid":false,"given":"Alessandra","family":"Pantaleo","sequence":"first","affiliation":[{"name":"Otolaryngology Unit, Department of Traslational Medicine and Neuroscience-DiBrain, University of Bari, 70124 Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Curatoli","sequence":"additional","affiliation":[{"name":"Otolaryngology Unit, Department of Traslational Medicine and Neuroscience-DiBrain, University of Bari, 70124 Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5772-6756","authenticated-orcid":false,"given":"Giada","family":"Cavallaro","sequence":"additional","affiliation":[{"name":"Otolaryngology Unit, Madonna delle Grazie Hospital of Matera, 75100 Matera, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debora","family":"Auricchio","sequence":"additional","affiliation":[{"name":"Otolaryngology Unit, Department of Traslational Medicine and Neuroscience-DiBrain, University of Bari, 70124 Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5958-8086","authenticated-orcid":false,"given":"Alessandra","family":"Murri","sequence":"additional","affiliation":[{"name":"Otolaryngology Unit, Department of Traslational Medicine and Neuroscience-DiBrain, University of Bari, 70124 Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6214-2336","authenticated-orcid":false,"given":"Nicola","family":"Quaranta","sequence":"additional","affiliation":[{"name":"Otolaryngology Unit, Department of Traslational Medicine and Neuroscience-DiBrain, University of Bari, 70124 Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,1,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2435","DOI":"10.1007\/s00405-018-5100-7","article-title":"The Impact of Rehabilitation on Quality of Life after Hearing Loss: A Systematic Review","volume":"275","author":"Brodie","year":"2018","journal-title":"Eur. Arch. Otorhinolaryngol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1080\/00016489.2023.2210618","article-title":"The Effect of Cochlear Implant and Bimodal Stimulation on Tinnitus: A Multinational Survey","volume":"143","author":"Quaranta","year":"2023","journal-title":"Acta Otolaryngol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1001\/jamaoto.2016.4642","article-title":"Addressing Estimated Hearing Loss in Adults in 2060","volume":"143","author":"Goman","year":"2017","journal-title":"JAMA Otolaryngol. Head Neck Surg."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.otc.2019.09.004","article-title":"Cochlear Implant","volume":"53","author":"Naples","year":"2020","journal-title":"Otolaryngol. Clin. N. Am."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1097\/AUD.0000000000001260","article-title":"American Cochlear Implant Alliance Task Force Guidelines for Clinical Assessment and Management of Adult Cochlear Implantation for Single-Sided Deafness","volume":"43","author":"Dillon","year":"2022","journal-title":"Ear Hear."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1097\/AUD.0000000000001204","article-title":"American Cochlear Implant Alliance Task Force Guidelines for Clinical Assessment and Management of Cochlear Implantation in Children with Single-Sided Deafness","volume":"43","author":"Park","year":"2022","journal-title":"Ear Hear."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1177\/0194599818764329","article-title":"Minimum Reporting Standards for Adult Cochlear Implantation","volume":"159","author":"Adunka","year":"2018","journal-title":"Otolaryngol. Head. Neck Surg."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1097\/MAO.0000000000001620","article-title":"Meta-Analysis of Cochlear Implantation Outcomes Evaluated With General Health-Related Patient-Reported Outcome Measures","volume":"39","author":"McRackan","year":"2018","journal-title":"Otol. Neurotol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"915","DOI":"10.3109\/00016489.2014.909604","article-title":"Development and Validation of a Questionnaire for Hearing Implant Users to Self-Assess Their Auditory Abilities in Everyday Communication Situations: The Hearing Implant Sound Quality Index (HISQUI19)","volume":"134","author":"Amann","year":"2014","journal-title":"Acta Otolaryngol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1080\/14992020400050014","article-title":"The Speech, Spatial and Qualities of Hearing Scale (SSQ)","volume":"43","author":"Gatehouse","year":"2004","journal-title":"Int. J. Audiol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1097\/AUD.0000000000000601","article-title":"A Cross-Sectional Questionnaire Study of Tinnitus Awareness and Impact in a Population of Adult Cochlear Implant Users","volume":"40","author":"Gomersall","year":"2019","journal-title":"Ear Hear."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"2331216516669329","DOI":"10.1177\/2331216516669329","article-title":"Perception of Sung Speech in Bimodal Cochlear Implant Users","volume":"20","author":"Crew","year":"2016","journal-title":"Trends Hear."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1159\/000355700","article-title":"Availability of Binaural Cues for Bilateral Implant Recipients and Bimodal Listeners with and without Preserved Hearing in the Implanted Ear","volume":"19","author":"Gifford","year":"2014","journal-title":"Audiol. Neurootol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1097\/AUD.0000000000000657","article-title":"Bimodal Hearing or Bilateral Cochlear Implants? Ask the Patient","volume":"40","author":"Gifford","year":"2019","journal-title":"Ear Hear."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"2331216520902001","DOI":"10.1177\/2331216520902001","article-title":"Frequency Following Response and Speech Recognition Benefit for Combining a Cochlear Implant and Contralateral Hearing Aid","volume":"24","author":"Kessler","year":"2020","journal-title":"Trends Hear."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1044\/2020_JSLHR-19-00304","article-title":"Clinical Application of Spectral Modulation Detection: Speech Recognition Benefit for Combining a Cochlear Implant and Contralateral Hearing Aid","volume":"63","author":"Kessler","year":"2020","journal-title":"J. Speech Lang. Hear. Res."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"2331216517699530","DOI":"10.1177\/2331216517699530","article-title":"Self-Reported Usage, Functional Benefit, and Audiologic Characteristics of Cochlear Implant Patients Who Use a Contralateral Hearing Aid","volume":"21","author":"Neuman","year":"2017","journal-title":"Trends Hear."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.heares.2011.11.014","article-title":"Contrasting Benefits from Contralateral Implants and Hearing Aids in Cochlear Implant Users","volume":"288","year":"2012","journal-title":"Hear. Res."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"2331216518771173","DOI":"10.1177\/2331216518771173","article-title":"Effects of Cochlear Implantation on Binaural Hearing in Adults With Unilateral Hearing Loss","volume":"22","author":"Buss","year":"2018","journal-title":"Trends Hear."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1097\/01.aud.0000246816.50820.42","article-title":"Simultaneous Bilateral Cochlear Implantation in Adults: A Multicenter Clinical Study","volume":"27","author":"Litovsky","year":"2006","journal-title":"Ear Hear."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1682","DOI":"10.1097\/MAO.0000000000000632","article-title":"From Hearing with a Cochlear Implant and a Contralateral Hearing Aid (CI\/HA) to Hearing with Two Cochlear Implants (CI\/CI): A within-Subject Design Comparison","volume":"35","author":"Luntz","year":"2014","journal-title":"Otol. Neurotol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"760","DOI":"10.3766\/jaaa.18.9.5","article-title":"A Meta-Analytic Comparison of Binaural Benefits between Bilateral Cochlear Implants and Bimodal Stimulation","volume":"18","author":"Schafer","year":"2007","journal-title":"J. Am. Acad. Audiol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1044\/1059-0889(2013\/11-0031)","article-title":"Transitioning from Bimodal to Bilateral Cochlear Implant Listening: Speech Recognition and Localization in Four Individuals","volume":"23","author":"Potts","year":"2014","journal-title":"Am. J. Audiol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1097\/MAO.0000000000001750","article-title":"Bilateral Cochlear Implantation Versus Bimodal Hearing in Patients With Functional Residual Hearing: A Within-Subjects Comparison of Audiologic Performance and Quality of Life","volume":"39","author":"Yawn","year":"2018","journal-title":"Otol. Neurotol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1097\/00129492-200103000-00014","article-title":"Tinnitus Suppression in Patients with Cochlear Implants","volume":"22","author":"Ruckenstein","year":"2001","journal-title":"Otol. Neurotol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1001\/archotol.1992.01880120017004","article-title":"Tinnitus Suppression Following Cochlear Implantation. A Multifactorial Investigation","volume":"118","author":"Souliere","year":"1992","journal-title":"Arch. Otolaryngol. Head. Neck Surg."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1080\/14992020400050033","article-title":"Tinnitus and Cochlear Implantation","volume":"43","author":"Quaranta","year":"2004","journal-title":"Int. J. Audiol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"S99","DOI":"10.1080\/14992020600783079","article-title":"Self-Reported Benefits from Successive Bilateral Cochlear Implantation in Post-Lingually Deafened Adults: Randomised Controlled Trial","volume":"45","author":"Barton","year":"2006","journal-title":"Int. J. Audiol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1002\/lary.25493","article-title":"Effect of Unilateral and Simultaneous Bilateral Cochlear Implantation on Tinnitus: A Prospective Study","volume":"126","author":"Smulders","year":"2016","journal-title":"Laryngoscope"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1177\/108471380400800203","article-title":"Music Perception with Cochlear Implants: A Review","volume":"8","author":"McDermott","year":"2004","journal-title":"Trends Amplif."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1177\/0194599818760559","article-title":"Music Appreciation after Cochlear Implantation in Adult Patients: A Systematic Review","volume":"158","author":"Riley","year":"2018","journal-title":"Otolaryngol. Head. Neck Surg."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1177\/1084713807304357","article-title":"Binaural-Bimodal Fitting or Bilateral Implantation for Managing Severe to Profound Deafness: A Review","volume":"11","author":"Ching","year":"2007","journal-title":"Trends Amplif."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1044\/2020_JSLHR-20-00390","article-title":"Bimodal Benefit for Music Perception: Effect of Acoustic Bandwidth","volume":"64","author":"Gifford","year":"2021","journal-title":"J. Speech Lang. Hear. Res."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1159\/000206491","article-title":"How Much Residual Hearing Is \u201cuseful\u201d for Music Perception with Cochlear Implants?","volume":"14","author":"James","year":"2009","journal-title":"Audiol. Neurootol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1002\/lary.28285","article-title":"Safety-Relevant Environmental Sound Identification in Cochlear Implant Candidates and Users","volume":"130","author":"Hamel","year":"2020","journal-title":"Laryngoscope"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1097\/AUD.0000000000000684","article-title":"Development of the Cochlear Implant Quality of Life Item Bank","volume":"40","author":"McRackan","year":"2019","journal-title":"Ear Hear."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"292","DOI":"10.3766\/jaaa.19047","article-title":"How Does Quality of Life Relate to Auditory Abilities? A Subitem Analysis of the Nijmegen Cochlear Implant Questionnaire","volume":"31","author":"Vasil","year":"2020","journal-title":"J. Am. Acad. Audiol."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1001\/jamaoto.2017.1182","article-title":"Use of Adult Patient Focus Groups to Develop the Initial Item Bank for a Cochlear Implant Quality-of-Life Instrument","volume":"143","author":"McRackan","year":"2017","journal-title":"JAMA Otolaryngol. Head. Neck Surg."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"788899","DOI":"10.3389\/fnins.2021.788899","article-title":"Perception of Environmental Sounds in Cochlear Implant Users: A Systematic Review","volume":"15","author":"Shafiro","year":"2021","journal-title":"Front. Neurosci."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"e964","DOI":"10.1097\/MAO.0000000000002006","article-title":"Environmental Sound Awareness in Experienced Cochlear Implant Users and Cochlear Implant Candidates","volume":"39","author":"McMahon","year":"2018","journal-title":"Otol. Neurotol."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"e1111","DOI":"10.1097\/MAO.0000000000002767","article-title":"Are There Real-World Benefits to Bimodal Listening?","volume":"41","author":"Nyirjesy","year":"2020","journal-title":"Otol. Neurotol."}],"container-title":["Audiology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2039-4349\/15\/1\/6\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T10:32:02Z","timestamp":1759919522000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2039-4349\/15\/1\/6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,20]]},"references-count":41,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,2]]}},"alternative-id":["audiolres15010006"],"URL":"https:\/\/doi.org\/10.3390\/audiolres15010006","relation":{},"ISSN":["2039-4349"],"issn-type":[{"value":"2039-4349","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,20]]}}}