{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T18:13:36Z","timestamp":1779387216501,"version":"3.53.1"},"reference-count":39,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2026,5,10]],"date-time":"2026-05-10T00:00:00Z","timestamp":1778371200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Audiology Research"],"abstract":"<jats:p>Background: Eustachian Tube Dysfunction (ETD) presents significant diagnostic challenges, particularly in patients with chronic nasal disease, which often mimic or complicate ETD symptoms. Tubomanometry (TMM) is emerging as an objective tool for diagnosing ETD, but its application in patients with concurrent nasal pathologies remains underexplored. Methods: One hundred patients with concurrent ETD and chronic nasal disease were recruited. They were categorized into three groups: chronic rhinitis (35 patients, group A), nasal septal deviation (31 patients, group B) and chronic rhinosinusitis with polyps (34 patients, group C). Treatments included nasal irrigation, septoplasty, and nasal polypectomy with functional endoscopic sinus surgery, respectively. The TMM parameters (R, C2 and C2\u2013C1 scores) were assessed before and after interventions. The patient reported outcome measures (ETDQ-7 and NOSE scores) were also recorded and statistically correlated with TMM measures. Results: Group A showed improvements in R, C2 and C2\u2013C1 scores and mild post-treatment reductions in ETDQ-7 and NOSE scores. Similar improvements were observed in Group B, with significant symptom reduction post-septoplasty, particularly on the side of the nasal septal deviation. Group C demonstrated the greatest improvement, with significant improvements in TMM values and substantial reductions in both ETDQ-7 and NOSE scores. The statistical results revealed correlations between the treatment of nasal pathologies and ETDQ-7 and NOSE scores. Conclusions: All TMM parameters improved in each group following the nasal intervention. This study highlights the utility of TMM in evaluating ETD in the context of chronic nasal disease and suggests that treating underlying nasal conditions can significantly alleviate ETD symptoms.<\/jats:p>","DOI":"10.3390\/audiolres16030070","type":"journal-article","created":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T16:46:18Z","timestamp":1779381978000},"page":"70","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Tubomanometry and Symptom Outcomes in Eustachian Tube Dysfunction Associated with Chronic Nasal Disease"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4355-2070","authenticated-orcid":false,"given":"Sofia","family":"Anastasiadou","sequence":"first","affiliation":[{"name":"1st Academic ENT Department, Aristotle University of Thessaloniki, AHEPA Hospital, No. 1, Stilponos Kyriakidi St., 546 36 Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2488-5539","authenticated-orcid":false,"given":"Petros","family":"Karkos","sequence":"additional","affiliation":[{"name":"1st Academic ENT Department, Aristotle University of Thessaloniki, AHEPA Hospital, No. 1, Stilponos Kyriakidi St., 546 36 Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jannis","family":"Constantinidis","sequence":"additional","affiliation":[{"name":"1st Academic ENT Department, Aristotle University of Thessaloniki, AHEPA Hospital, No. 1, Stilponos Kyriakidi St., 546 36 Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3509-6519","authenticated-orcid":false,"given":"George","family":"Psillas","sequence":"additional","affiliation":[{"name":"1st Academic ENT Department, Aristotle University of Thessaloniki, AHEPA Hospital, No. 1, Stilponos Kyriakidi St., 546 36 Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,5,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"5135","DOI":"10.1007\/s00405-024-08724-8","article-title":"Assessing the usefulness of tubomanometry as a diagnostic tool in Eustachian tube dysfunction","volume":"281","author":"Herrera","year":"2024","journal-title":"Eur. 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