{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T15:17:05Z","timestamp":1779203825276,"version":"3.51.4"},"reference-count":129,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2023,1,4]],"date-time":"2023-01-04T00:00:00Z","timestamp":1672790400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioengineering"],"abstract":"<jats:p>The ayurvedic herb Emblica officinalis (E. officinalis) is a gift to mankind to acquire a healthy lifestyle. It has great therapeutic and nutritional importance. Emblica officinalis, also known as Indian gooseberry or Amla, is a member of the Euphorbiaceae family. Amla is beneficial for treating illnesses in all its forms. The most crucial component is a fruit, which is also the most common. It is used frequently in Indian medicine as a restorative, diuretic, liver tonic, refrigerant, stomachic, laxative, antipyretic, hair tonic, ulcer preventive, and for the common cold and fever. Hyperlipidemia is also known as high cholesterol or an increase in one or more lipid-containing blood proteins. Various phytocompounds, including polyphenols, vitamins, amino acids, fixed oils, and flavonoids, are present in the various parts of E. officinalis. E. officinalis has been linked to a variety of pharmacological effects in earlier studies, including hepatoprotective, immunomodulatory, antimicrobial, radioprotective, and hyperlipidemic effects. The amla-derived active ingredients and food products nevertheless encounter challenges such as instability and interactions with other food matrices. Considering the issue from this perspective, food component nanoencapsulation is a young and cutting-edge field for controlled and targeted delivery with a range of preventative activities. The nanoformulation of E. officinalis facilitates the release of active components or food ingredients, increased bioaccessibility, enhanced therapeutic activities, and digestion in the human body. Accordingly, the current review provides a summary of the phytoconstituents of E. officinalis, pharmacological actions detailing the plant E. officinalis\u2019s traditional uses, and especially hyperlipidemic activity. Correspondingly, the article describes the uses of nanotechnology in amla therapeutics and functional ingredients.<\/jats:p>","DOI":"10.3390\/bioengineering10010064","type":"journal-article","created":{"date-parts":[[2023,1,5]],"date-time":"2023-01-05T02:28:53Z","timestamp":1672885733000},"page":"64","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Attenuation of Hyperlipidemia by Medicinal Formulations of Emblica officinalis Synergized with Nanotechnological Approaches"],"prefix":"10.3390","volume":"10","author":[{"given":"Puttasiddaiah","family":"Rachitha","sequence":"first","affiliation":[{"name":"P.G. Department of Biotechnology, Teresian College, Siddarthanagar, Mysuru 570011, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krupashree","family":"Krishnaswamy","sequence":"additional","affiliation":[{"name":"Biochemistry Department, Central Food Technological Research Institute, Mysore 570006, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renal Antoinette","family":"Lazar","sequence":"additional","affiliation":[{"name":"P.G. Department of Biotechnology, Teresian College, Siddarthanagar, Mysuru 570011, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1565-5918","authenticated-orcid":false,"given":"Vijai Kumar","family":"Gupta","sequence":"additional","affiliation":[{"name":"Biorefining and Advanced Materials Research Center, Scotland\u2019s Rural College (SRUC), Edinburgh EH9 3JG, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4301-7614","authenticated-orcid":false,"given":"Baskaran Stephen","family":"Inbaraj","sequence":"additional","affiliation":[{"name":"Department of Food Science, Fu Jen Catholic University, New Taipei City 242 05, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vinay Basavegowda","family":"Raghavendra","sequence":"additional","affiliation":[{"name":"P.G. Department of Biotechnology, Teresian College, Siddarthanagar, Mysuru 570011, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6493-5217","authenticated-orcid":false,"given":"Minaxi","family":"Sharma","sequence":"additional","affiliation":[{"name":"Haute Ecole Provinciale de Hainaut-Condorcet, 7800 Ath, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6174-0024","authenticated-orcid":false,"given":"Kandi","family":"Sridhar","sequence":"additional","affiliation":[{"name":"Department of Food Technology, Koneru Lakshmaiah Education Foundation Deemed to be University, Vaddeswaram 522502, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,1,4]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Ezeh, K.J., and Ezeudemba, O. (2021). 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