{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T20:23:59Z","timestamp":1792441439268,"version":"4.5.0"},"reference-count":61,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2023,2,16]],"date-time":"2023-02-16T00:00:00Z","timestamp":1676505600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioengineering"],"abstract":"<jats:p>(1) Background: Mitochondrial dysfunction and redox imbalance seem to be involved in fibromyalgia (FM) pathogenesis. The results of our previous studies suggest that whole-body vibration training (WBVT) would improve redox status markers, increase blood irisin levels, and ameliorate the body composition of women with FM. (2) Objective: The current study aimed to investigate WBVT on oxidative stress markers, plasma irisin levels, and body composition in women with FM. (3) Methods: Forty women with FM were randomized into WBVT or untrained (UN) groups. Before and after 6 weeks of WBVT, body composition was assessed by dual-energy radiological absorptiometry (DXA), and inflammatory marker activities were measured by enzymatic assay. (4) Results: Body composition, blood irisin levels, and oxidative stress markers were similar between UN and WBVT groups before the intervention. After 6 weeks of intervention, the WBVT group presented higher irisin levels (WBVT: 316.98 \u00b1 109.24 mg\u00b7dL\u00b3, WBVT: 477.61 \u00b1 267.92 mg\u00b7dL\u00b3, p = 0.01) and lower TBARS levels (UN: 0.39 \u00b1 0.02 nmol MDA\/mg protein, WBVT: 0.24 \u00b1 0.06 nmol MDA\/mg protein, p = 0.001) and visceral adipose tissue mass (UN: 1.37 \u00b1 0.49 kg, WBVT: 0.69 \u00b1 0.54 kg, p = 0.001) compared to the UN group. (5) Conclusions: Six weeks of WBVT improves blood redox status markers, increases irisin levels, and reduces visceral adipose tissue mass, favoring less cell damage and more outstanding oxidative balance in women with FM.<\/jats:p>","DOI":"10.3390\/bioengineering10020260","type":"journal-article","created":{"date-parts":[[2023,2,16]],"date-time":"2023-02-16T04:51:46Z","timestamp":1676523106000},"page":"260","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Whole-Body Vibration Training on Oxidative Stress Markers, Irisin Levels, and Body Composition in Women with Fibromyalgia: A Randomized Controlled Trial"],"prefix":"10.3390","volume":"10","author":[{"given":"Jousielle M\u00e1rcia","family":"dos Santos","sequence":"first","affiliation":[{"name":"Multicenter Graduate Program in Physiological Sciences, Brazilian Society of Physiology, Diamantina 39100-000, Brazil"},{"name":"Graduate Program in Functional Performance and Rehabilitation, Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina 39100-000, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0227-3884","authenticated-orcid":false,"given":"Redha","family":"Taiar","sequence":"additional","affiliation":[{"name":"MAT\u00e9riaux et Ing\u00e9nierie M\u00e9canique, Universit\u00e9 de Reims Champagne Ardenne, 51100 Reims, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3809-7285","authenticated-orcid":false,"given":"Vanessa Gon\u00e7alves C\u00e9sar","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"Multicenter Graduate Program in Physiological Sciences, Brazilian Society of Physiology, Diamantina 39100-000, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0381-5622","authenticated-orcid":false,"given":"Vanessa Kelly","family":"da Silva Lage","sequence":"additional","affiliation":[{"name":"Multicenter Graduate Program in Physiological Sciences, Brazilian Society of Physiology, Diamantina 39100-000, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro Henrique","family":"Scheidt Figueiredo","sequence":"additional","affiliation":[{"name":"Graduate Program in Functional Performance and Rehabilitation, Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina 39100-000, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrique Silveira","family":"Costa","sequence":"additional","affiliation":[{"name":"Graduate Program in Functional Performance and Rehabilitation, Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina 39100-000, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa","family":"Pereira Lima","sequence":"additional","affiliation":[{"name":"Graduate Program in Functional Performance and Rehabilitation, Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina 39100-000, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9969-9573","authenticated-orcid":false,"given":"Borja","family":"Sa\u00f1udo","sequence":"additional","affiliation":[{"name":"Department of Physical Education and Sports, Universidad de Sevilla, 41013 Seville, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4718-448X","authenticated-orcid":false,"given":"M\u00e1rio","family":"Bernardo-Filho","sequence":"additional","affiliation":[{"name":"Mechanical Vibration Laboratory and Integrative Practices, Department of Biophysics and Biometrics, Institute of Biology Roberto Alc\u00e2ntara Gomes and Piquet Carneiro Polyclinic, Rio de Janeiro State University, Rio de Janeiro 20950-003, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9263-1576","authenticated-orcid":false,"given":"Dan\u00fabia da Cunha de","family":"S\u00e1-Caputo","sequence":"additional","affiliation":[{"name":"Mechanical Vibration Laboratory and Integrative Practices, Department of Biophysics and Biometrics, Institute of Biology Roberto Alc\u00e2ntara Gomes and Piquet Carneiro Polyclinic, Rio de Janeiro State University, Rio de Janeiro 20950-003, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco Fabr\u00edcio","family":"Dias Peixoto","sequence":"additional","affiliation":[{"name":"Multicenter Graduate Program in Physiological Sciences, Brazilian Society of Physiology, Diamantina 39100-000, Brazil"},{"name":"Graduate Program in Health Sciences, Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina 39100-00, 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