{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T18:03:36Z","timestamp":1779386616893,"version":"3.53.1"},"reference-count":31,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2023,6,12]],"date-time":"2023-06-12T00:00:00Z","timestamp":1686528000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82271993"],"award-info":[{"award-number":["82271993"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81871354"],"award-info":[{"award-number":["81871354"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["61931013"],"award-info":[{"award-number":["61931013"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82171886"],"award-info":[{"award-number":["82171886"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["2019QL023"],"award-info":[{"award-number":["2019QL023"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["2022FY066"],"award-info":[{"award-number":["2022FY066"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Academic promotion program of Shandong First Medical University","award":["82271993"],"award-info":[{"award-number":["82271993"]}]},{"name":"Academic promotion program of Shandong First Medical University","award":["81871354"],"award-info":[{"award-number":["81871354"]}]},{"name":"Academic promotion program of Shandong First Medical University","award":["61931013"],"award-info":[{"award-number":["61931013"]}]},{"name":"Academic promotion program of Shandong First Medical University","award":["82171886"],"award-info":[{"award-number":["82171886"]}]},{"name":"Academic promotion program of Shandong First Medical University","award":["2019QL023"],"award-info":[{"award-number":["2019QL023"]}]},{"name":"Academic promotion program of Shandong First Medical University","award":["2022FY066"],"award-info":[{"award-number":["2022FY066"]}]},{"name":"Foundation of Youth Talent of Shandong Provincial Hospital (YG)","award":["82271993"],"award-info":[{"award-number":["82271993"]}]},{"name":"Foundation of Youth Talent of Shandong Provincial Hospital (YG)","award":["81871354"],"award-info":[{"award-number":["81871354"]}]},{"name":"Foundation of Youth Talent of Shandong Provincial Hospital (YG)","award":["61931013"],"award-info":[{"award-number":["61931013"]}]},{"name":"Foundation of Youth Talent of Shandong Provincial Hospital (YG)","award":["82171886"],"award-info":[{"award-number":["82171886"]}]},{"name":"Foundation of Youth Talent of Shandong Provincial Hospital (YG)","award":["2019QL023"],"award-info":[{"award-number":["2019QL023"]}]},{"name":"Foundation of Youth Talent of Shandong Provincial Hospital (YG)","award":["2022FY066"],"award-info":[{"award-number":["2022FY066"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioengineering"],"abstract":"<jats:p>Sigmoid sinus wall dehiscence (SSWD) is an important etiology of venous pulsatile tinnitus (VPT) and is treated by sigmoid sinus wall reconstruction (SSWR). This study aimed to investigate the therapeutic effects of the different degrees of SSWR and the prognostic effect in patients with VPT. Personalized models of three patients with SSWD (control), 3\/4SSWD, 1\/2SSWD, 1\/4SSWD, and 0SSWD were reconstructed. A multiphysics interaction approach was applied to elucidate the biomechanical and acoustic changes. Results revealed that after SSWR, the average pressure of venous vessel on the SSWD region reduced by 33.70 \u00b1 12.53%, 35.86 \u00b1 12.39%, and 39.70 \u00b1 12.45% (mean \u00b1 SD) in three patients with 3\/4SSWD, 1\/2SSWD, and 1\/4SSWD. The maximum displacement of the SSWR region reduced by 25.91 \u00b1 30.20%, 37.20 \u00b1 31.47%, 52.60 \u00b1 34.66%, and 79.35 \u00b1 18.13% (mean \u00b1 SD) in three patients with 3\/4SSWD, 1\/2SSWD, 1\/4SSWD, and 0SSWD, with a magnitude approximately 10\u22123 times that of the venous vessel in the SSWD region. The sound pressure level at the tympanum reduced by 23.72 \u00b1 1.91%, 31.03 \u00b1 14.40%, 45.62 \u00b1 19.11%, and 128.46 \u00b1 15.46% (mean \u00b1 SD). The SSWR region was still loaded with high stress in comparison to the surrounding region. The SSWR region of the temporal bone effectively shielded the high wall pressure and blocked the transmission of venous vessel vibration to the inner ear. Patients with inadequate SSWR still had residual VPT symptoms despite the remission of VPT symptoms. Complete SSWR could completely solve VPT issues. High-stress distribution of the SSWR region may be the cause of the recurrence of VPT symptoms.<\/jats:p>","DOI":"10.3390\/bioengineering10060715","type":"journal-article","created":{"date-parts":[[2023,6,13]],"date-time":"2023-06-13T02:56:34Z","timestamp":1686624994000},"page":"715","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Multiphysics Interaction Analysis of the Therapeutic Effects of the Sigmoid Sinus Wall Reconstruction in Patients with Venous Pulsatile Tinnitus"],"prefix":"10.3390","volume":"10","author":[{"given":"Zhenxia","family":"Mu","sequence":"first","affiliation":[{"name":"Department of Radiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lihui","family":"Zhuang","sequence":"additional","affiliation":[{"name":"Department of Radiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pengfei","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Gao","sequence":"additional","affiliation":[{"name":"Faculty of Environment and Life Science, Beijing University of Technology, Beijing 100124, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youjun","family":"Liu","sequence":"additional","affiliation":[{"name":"Faculty of Environment and Life Science, Beijing University of Technology, Beijing 100124, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenchang","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shifeng","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Radiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ximing","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Radiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,6,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2896","DOI":"10.1007\/s00330-020-07415-2","article-title":"CT venography correlate of transverse sinus stenosis and venous transstenotic pressure gradient in unilateral pulsatile tinnitus patients with sigmoid sinus wall anomalies","volume":"31","author":"Zhao","year":"2021","journal-title":"Eur. 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