{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T22:01:59Z","timestamp":1763071319054,"version":"build-2065373602"},"reference-count":0,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T00:00:00Z","timestamp":1716336000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Cancer Institute","award":["1U01CA248226-01","1R01NR019585-01A1","1R01HL165218-01A1","2320952","W81XWH-21-1-0345","W81XWH 19-1-0668","W81XWH-21-1-0725"],"award-info":[{"award-number":["1U01CA248226-01","1R01NR019585-01A1","1R01HL165218-01A1","2320952","W81XWH-21-1-0345","W81XWH 19-1-0668","W81XWH-21-1-0725"]}]},{"name":"National Institute of Nursing Research","award":["1U01CA248226-01","1R01NR019585-01A1","1R01HL165218-01A1","2320952","W81XWH-21-1-0345","W81XWH 19-1-0668","W81XWH-21-1-0725"],"award-info":[{"award-number":["1U01CA248226-01","1R01NR019585-01A1","1R01HL165218-01A1","2320952","W81XWH-21-1-0345","W81XWH 19-1-0668","W81XWH-21-1-0725"]}]},{"name":"National Heart, Lung, and Blood Institute","award":["1U01CA248226-01","1R01NR019585-01A1","1R01HL165218-01A1","2320952","W81XWH-21-1-0345","W81XWH 19-1-0668","W81XWH-21-1-0725"],"award-info":[{"award-number":["1U01CA248226-01","1R01NR019585-01A1","1R01HL165218-01A1","2320952","W81XWH-21-1-0345","W81XWH 19-1-0668","W81XWH-21-1-0725"]}]},{"name":"National Science Foundation","award":["1U01CA248226-01","1R01NR019585-01A1","1R01HL165218-01A1","2320952","W81XWH-21-1-0345","W81XWH 19-1-0668","W81XWH-21-1-0725"],"award-info":[{"award-number":["1U01CA248226-01","1R01NR019585-01A1","1R01HL165218-01A1","2320952","W81XWH-21-1-0345","W81XWH 19-1-0668","W81XWH-21-1-0725"]}]},{"name":"DOD Peer Reviewed Cancer Research Program","award":["1U01CA248226-01","1R01NR019585-01A1","1R01HL165218-01A1","2320952","W81XWH-21-1-0345","W81XWH 19-1-0668","W81XWH-21-1-0725"],"award-info":[{"award-number":["1U01CA248226-01","1R01NR019585-01A1","1R01HL165218-01A1","2320952","W81XWH-21-1-0345","W81XWH 19-1-0668","W81XWH-21-1-0725"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioengineering"],"abstract":"<jats:p>The umbilical or L3 vertebral body level is often used for body fat quantification using computed tomography. To explore the feasibility of using clinically acquired pelvic magnetic resonance imaging (MRI) for visceral fat measurement, we examined the correlation of visceral fat parameters at the umbilical and L5 vertebral body levels. We retrospectively analyzed T2-weighted half-Fourier acquisition single-shot turbo spin echo (HASTE) MR axial images from Crohn\u2019s disease patients who underwent MRI enterography of the abdomen and pelvis over a three-year period. We determined the area\/volume of subcutaneous and visceral fat from the umbilical and L5 levels and calculated the visceral fat ratio (VFR = visceral fat\/subcutaneous fat) and visceral fat index (VFI = visceral fat\/total fat). Statistical analyses involved correlation analysis between both levels, inter-rater analysis between two investigators, and inter-platform analysis between two image-analysis platforms. Correlational analysis of 32 patients yielded significant associations for VFI (r = 0.85; p &lt; 0.0001) and VFR (r = 0.74; p &lt; 0.0001). Intraclass coefficients for VFI and VFR were 0.846 and 0.875 (good agreement) between investigators and 0.831 and 0.728 (good and moderate agreement) between platforms. Our study suggests that the L5 level on clinically acquired pelvic MRIs may serve as a reference point for visceral fat quantification.<\/jats:p>","DOI":"10.3390\/bioengineering11060528","type":"journal-article","created":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T10:00:11Z","timestamp":1716372011000},"page":"528","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Quantification of Visceral Fat at the L5 Vertebral Body Level in Patients with Crohn\u2019s Disease Using T2-Weighted MRI"],"prefix":"10.3390","volume":"11","author":[{"given":"Favour","family":"Garuba","sequence":"first","affiliation":[{"name":"School of Medical Education, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9023-1683","authenticated-orcid":false,"given":"Aravinda","family":"Ganapathy","sequence":"additional","affiliation":[{"name":"School of Medical Education, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Spencer","family":"McKinley","sequence":"additional","affiliation":[{"name":"School of Medical Education, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2221-3512","authenticated-orcid":false,"given":"Karan H.","family":"Jani","sequence":"additional","affiliation":[{"name":"Mallinckrodt Institute of Radiology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriene","family":"Lovato","sequence":"additional","affiliation":[{"name":"Mallinckrodt Institute of Radiology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4550-8337","authenticated-orcid":false,"given":"Satish E.","family":"Viswanath","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, School of Engineering, Case Western Reserve University, Cleveland, OH 44106, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott","family":"McHenry","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Parakkal","family":"Deepak","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7470-3364","authenticated-orcid":false,"given":"David H.","family":"Ballard","sequence":"additional","affiliation":[{"name":"Mallinckrodt Institute of Radiology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,5,22]]},"container-title":["Bioengineering"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2306-5354\/11\/6\/528\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T14:46:36Z","timestamp":1760107596000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2306-5354\/11\/6\/528"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,22]]},"references-count":0,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2024,6]]}},"alternative-id":["bioengineering11060528"],"URL":"https:\/\/doi.org\/10.3390\/bioengineering11060528","relation":{},"ISSN":["2306-5354"],"issn-type":[{"type":"electronic","value":"2306-5354"}],"subject":[],"published":{"date-parts":[[2024,5,22]]}}}