{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T20:44:36Z","timestamp":1783975476854,"version":"3.55.0"},"reference-count":37,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2024,7,12]],"date-time":"2024-07-12T00:00:00Z","timestamp":1720742400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Shanghai Municipal Science and Technology Major Project","award":["21Y11903400"],"award-info":[{"award-number":["21Y11903400"]}]},{"name":"Shanghai Municipal Science and Technology Major Project","award":["2023ZDFC0303"],"award-info":[{"award-number":["2023ZDFC0303"]}]},{"name":"Shanghai Municipal Science and Technology Major Project","award":["YG2021QN70"],"award-info":[{"award-number":["YG2021QN70"]}]},{"name":"Shanghai Municipal Health Commission Key Supporting Disciplines","award":["21Y11903400"],"award-info":[{"award-number":["21Y11903400"]}]},{"name":"Shanghai Municipal Health Commission Key Supporting Disciplines","award":["2023ZDFC0303"],"award-info":[{"award-number":["2023ZDFC0303"]}]},{"name":"Shanghai Municipal Health Commission Key Supporting Disciplines","award":["YG2021QN70"],"award-info":[{"award-number":["YG2021QN70"]}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["21Y11903400"],"award-info":[{"award-number":["21Y11903400"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["2023ZDFC0303"],"award-info":[{"award-number":["2023ZDFC0303"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["YG2021QN70"],"award-info":[{"award-number":["YG2021QN70"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioengineering"],"abstract":"<jats:p>We aimed to verify the feasibility of using shear wave elastography (SWE) to quantify knee scars and the elastic modulus of scar tissues. Overall, 16 participants underwent SWE assessments and range-of-motion measurement and completed the Knee Injury and Osteoarthritis Outcome Score. The inter-rater reliability for SWE in the suprapatellar bursa, below the patellar tendon, and in the medial and lateral trochlear groove remained within 0.861\u20130.907. The SWE values in the four regions increased with increasing knee angle, and significant differences were observed between the values for below the patellar tendon and the suprapatellar bursa at knee flexion angles of 60\u00b0 and 90\u00b0. The SWE values of the medial and lateral trochlear groove at 30\u00b0, 60\u00b0, and 90\u00b0 knee flexion were higher on the affected side. A negative correlation was observed between the SWE values for the lateral trochlear groove at 0\u00b0, 30\u00b0, and 60\u00b0 and those for below the patellar tendon at 0\u00b0 and the suprapatellar bursa at 30\u00b0 with both active and passive knee extension. The suprapatellar bursa value at 60\u00b0 exhibited a positive correlation with both knee flexion and passive knee flexion, whereas that of the suprapatellar bursa at 90\u00b0 exhibited a positive correlation with both the range of motion and passive range of motion. SWE is a replicable and effective method for detecting scar strength in the knee joint.<\/jats:p>","DOI":"10.3390\/bioengineering11070706","type":"journal-article","created":{"date-parts":[[2024,7,12]],"date-time":"2024-07-12T08:16:57Z","timestamp":1720772217000},"page":"706","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Ultrasound Elastography Assessment of Knee Intra-Articular Adhesions at Varying Knee Angles"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6887-6442","authenticated-orcid":false,"given":"Jiling","family":"Ye","sequence":"first","affiliation":[{"name":"Rehabilitation Department, Shanghai Ninth People\u2019s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linjing","family":"Peng","sequence":"additional","affiliation":[{"name":"Med-X Research Institute, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200030, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angang","family":"Ding","sequence":"additional","affiliation":[{"name":"Ultrasound Medicine Department, Shanghai Ninth People\u2019s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0757-765X","authenticated-orcid":false,"given":"Shijie","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Computer Science, School of Computing, Tokyo Institute of Technology, Ookayama, Meguro-ku, Tokyo 152-8550, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Cai","sequence":"additional","affiliation":[{"name":"Rehabilitation Department, Shanghai Ninth People\u2019s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9809-0996","authenticated-orcid":false,"given":"Yifei","family":"Yao","sequence":"additional","affiliation":[{"name":"Med-X Research Institute, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200030, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,7,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1097\/01.bot.0000171881.11205.80","article-title":"Staged management of high-energy proximal tibia fractures (OTA types 41): The results of a prospective, standardized protocol","volume":"19","author":"Egol","year":"2005","journal-title":"J. Orthop. Trauma"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1177\/036354659202000503","article-title":"Loss of motion after anterior cruciate ligament reconstruction","volume":"20","author":"Harner","year":"1992","journal-title":"Am. J. Sports Med."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"682","DOI":"10.5435\/00124635-200711000-00007","article-title":"Arthrofibrosis of the knee","volume":"15","author":"Magit","year":"2007","journal-title":"J. Am. Acad. Orthop. Surg."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.arthro.2016.07.029","article-title":"Long-term results of arthroscopic arthrolysis for arthrofibrosis after anterior cruciate ligament reconstruction","volume":"33","author":"Mayr","year":"2017","journal-title":"Arthroscopy"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1007\/s00776-015-0731-7","article-title":"Quadriceps tendon pie-crusting release of stiff knees in total knee arthroplasty","volume":"20","author":"Zhang","year":"2015","journal-title":"J. Orthop. Sci."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"S179","DOI":"10.1016\/j.otsr.2014.06.026","article-title":"Post-traumatic knee stiffness: Surgical techniques","volume":"101","author":"Pujol","year":"2015","journal-title":"Orthop. Traumatol. Surg. Res."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1302\/0301-620X.45B3.483","article-title":"Quadricepsplasty","volume":"45","author":"Nicoll","year":"1963","journal-title":"J. Bone Joint Surg. Br."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"16469","DOI":"10.1038\/srep16469","article-title":"Fibrosis is a common outcome following total knee arthroplasty","volume":"5","author":"Abdul","year":"2015","journal-title":"Sci. Rep."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1016\/j.bbadis.2012.12.013","article-title":"Coagulation and coagulation signalling in fibrosis","volume":"1832","author":"Mercer","year":"2013","journal-title":"Biochim. Biophys. Acta"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.arth.2017.08.002","article-title":"Risk factors, outcomes, and timing of manipulation under anesthesia after total knee arthroplasty","volume":"33","author":"Newman","year":"2018","journal-title":"J. Arthroplasty"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1007\/s00264-022-05344-x","article-title":"Treatment of arthrofibrosis and stiffness after total knee arthroplasty: An updated review of the literature","volume":"46","author":"Haffar","year":"2022","journal-title":"Int. Orthop."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s10195-020-00563-7","article-title":"Arthrofibrosis after total knee arthroplasty: Patients with keloids at risk","volume":"22","author":"Flick","year":"2021","journal-title":"J. Orthop. Traumatol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1302\/0301-620X.102B10.BJJ-2020-0841.R1","article-title":"Quantification of intra-articular fibrosis in patients with stiff knee arthroplasties using metal-reduction MRI","volume":"102-B","author":"Attard","year":"2020","journal-title":"Bone Joint J."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1177\/016173469101300201","article-title":"Elastography: A quantitative method for imaging the elasticity of biological tissues","volume":"13","author":"Ophir","year":"1991","journal-title":"Ultrason. Imaging"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1055\/s-0033-1335205","article-title":"EFSUMB guidelines and recommendations on the clinical use of ultrasound elastography. Part 1: Basic principles and technology","volume":"34","author":"Bamber","year":"2013","journal-title":"Ultraschall Med."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/j.ultrasmedbio.2022.01.014","article-title":"Ultrasound shear wave elastography of the intervertebral disc and idiopathic scoliosis: A systematic review","volume":"48","author":"Moens","year":"2022","journal-title":"Ultrasound Med. Biol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"4616","DOI":"10.1007\/s00330-022-08601-0","article-title":"Prediction of high-risk esophageal varices in patients with chronic liver disease with point and 2D shear wave elastography: A systematic review and meta-analysis","volume":"32","author":"Liu","year":"2022","journal-title":"Eur. Radiol."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Mao, Y., Lim, H., Ni, M., Yan, W., Wong, D., and Cheung, J. (2022). Breast tumour classification using ultrasound elastography with machine learning: A systematic scoping review. Cancers, 14.","DOI":"10.3390\/cancers14020367"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1007\/s40279-019-01137-2","article-title":"Comparing the effectiveness of blood flow restriction and traditional heavy load resistance training in the post-surgery rehabilitation of anterior cruciate ligament reconstruction patients: A UK national health service randomised controlled trial","volume":"49","author":"Hughes","year":"2019","journal-title":"Sports Med."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"2730","DOI":"10.1177\/0363546517718827","article-title":"Results of anterior cruciate ligament reconstruction with patellar tendon autografts: Objective factors associated with the development of osteoarthritis at 20 to 33 years after surgery","volume":"45","author":"Shelbourne","year":"2017","journal-title":"Am. J. Sports Med."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"88","DOI":"10.2519\/jospt.1998.28.2.88","article-title":"Knee Injury and Osteoarthritis Outcome Score (KOOS)\u2014Development of a self-administered outcome measure","volume":"28","author":"Roos","year":"1998","journal-title":"J. Orthop. Sports Phys. Ther."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1016\/j.joca.2016.03.010","article-title":"Knee Injury and Osteoarthritis Outcome Score (KOOS): Systematic review and meta-analysis of measurement properties","volume":"24","author":"Collins","year":"2016","journal-title":"Osteoarthritis Cartilage"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1007\/s00402-012-1647-8","article-title":"The aetiology of total knee arthroplasty failure influences the improvement in knee function","volume":"133","author":"Bieger","year":"2013","journal-title":"Arch. Orthop. Trauma Surg."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"1536","DOI":"10.1007\/s00167-013-2547-3","article-title":"Intra-articular injection of hyaluronic acid for the reduction in joint adhesion formation in a rabbit model of knee injury","volume":"22","author":"Wang","year":"2014","journal-title":"Knee Surg. Sports Traumatol. Arthrosc."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.arth.2005.03.014","article-title":"The stiff total knee arthroplasty: Causality and solution","volume":"20","author":"Scuderi","year":"2005","journal-title":"J. Arthroplasty"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"23324","DOI":"10.1038\/s41598-021-02730-0","article-title":"Correlation between elastic modulus and clinical severity of pathological scars: A cross-sectional study","volume":"11","author":"Hang","year":"2021","journal-title":"Sci. Rep."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.jbmt.2021.03.009","article-title":"Hamstring strains in professional rugby players result in increased fascial stiffness without muscle quality changes as assessed using shear wave elastography","volume":"27","author":"Kawai","year":"2021","journal-title":"J. Bodyw. Mov. Ther."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1016\/j.burns.2020.05.009","article-title":"Objective quantification of burn scar stiffness using shear-wave elastography: Initial evidence of validity","volume":"46","author":"DeJong","year":"2020","journal-title":"Burns"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1089\/wound.2021.0069","article-title":"Small leucine-rich proteoglycans in tendon wound healing","volume":"11","author":"Xu","year":"2022","journal-title":"Adv. Wound Care"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"2080","DOI":"10.1007\/s00167-017-4791-4","article-title":"Achilles tendon elastic properties remain decreased in long term after rupture","volume":"26","author":"Frankewycz","year":"2018","journal-title":"Knee Surg. Sports Traumatol. Arthrosc."},{"key":"ref_31","unstructured":"McCarthy, J.G. (1990). Keloids and hypertophic scars. Plastic Surgery, Saunders."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1097\/00000637-199108000-00012","article-title":"In search of the optimal treatment of keloids: Report of a series and a review of the literature","volume":"27","author":"Lawrence","year":"1991","journal-title":"Ann. Plast. Surg."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1002\/jor.21588","article-title":"Myofibroblast cells are preferentially expressed early in a rabbit model of joint contracture","volume":"30","author":"Abdel","year":"2012","journal-title":"J. Orthop. Res."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.orthres.2003.08.012","article-title":"Rabbit knee model of post-traumatic joint contractures: The long-term natural history of motion loss and myofibroblasts","volume":"22","author":"Hildebrand","year":"2004","journal-title":"J. Orthop. Res."},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Harkos, C., Svensson, S., Emblem, K., and Stylianopoulos, T. (2022). Inducing biomechanical heterogeneity in brain tumor modeling by MR elastography: Effects on tumor growth, vascular density and delivery of therapeutics. Cancers, 14.","DOI":"10.3390\/cancers14040884"},{"key":"ref_36","first-page":"219","article-title":"Ultrasound elastographic assessment of the stiffness of the anteromedial knee joint capsule at varying knee angles","volume":"30","author":"Wadugodapitiya","year":"2019","journal-title":"Biomed. Mater. Eng."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1148\/rg.2017160116","article-title":"Shear-wave elastography: Basic physics and musculoskeletal applications","volume":"37","author":"Taljanovic","year":"2017","journal-title":"Radiographics"}],"container-title":["Bioengineering"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2306-5354\/11\/7\/706\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T15:15:33Z","timestamp":1760109333000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2306-5354\/11\/7\/706"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,12]]},"references-count":37,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2024,7]]}},"alternative-id":["bioengineering11070706"],"URL":"https:\/\/doi.org\/10.3390\/bioengineering11070706","relation":{},"ISSN":["2306-5354"],"issn-type":[{"value":"2306-5354","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,12]]}}}