{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T22:45:10Z","timestamp":1784673910308,"version":"3.55.0"},"reference-count":45,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2024,10,24]],"date-time":"2024-10-24T00:00:00Z","timestamp":1729728000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005357","name":"Slovak Research and Development Agency","doi-asserted-by":"publisher","award":["APVV 20-0184"],"award-info":[{"award-number":["APVV 20-0184"]}],"id":[{"id":"10.13039\/501100005357","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005357","name":"Slovak Research and Development Agency","doi-asserted-by":"publisher","award":["2\/0032\/23"],"award-info":[{"award-number":["2\/0032\/23"]}],"id":[{"id":"10.13039\/501100005357","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Slovak Grant Agency of the Ministry of Education of the Slovak Republic and the Slovak Academy of Sciences","award":["APVV 20-0184"],"award-info":[{"award-number":["APVV 20-0184"]}]},{"name":"Slovak Grant Agency of the Ministry of Education of the Slovak Republic and the Slovak Academy of Sciences","award":["2\/0032\/23"],"award-info":[{"award-number":["2\/0032\/23"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioengineering"],"abstract":"<jats:p>A tetracalcium phosphate\/monetite\/calcium sulfate hemihydrate powder cement mixture (CAS) in the form of a paste was used as a socket preservative to prevent alveolar ridge resorption after the extraction of the second premolar tooth in the mandible of a pig model. During the post-surgery period, the animals were monitored daily. No signs of inflammation, infection, or other complications were observed in the defect site for six months. Six months after surgery, the mandible defects in pigs were evaluated using macroscopic, histological, and radiological techniques. Treatment of the extraction sites with CAS biocement resulted in the uniform filling of the defects with alveolar bone tissue, characterized by a relatively smooth and homogeneous gum surface with no visible biocement residues. The formation of new bone tissue with osteoblasts, osteocytes, and mineralized matrices was confirmed. The results showed the similar morphology, thickness, and complete integration of the newly formed bone with the surrounding tissue. CAS biocement could be an effective material to prevent alveolar bone reduction as well as soft tissue loss and could support dental implant placement with long-term functionality.<\/jats:p>","DOI":"10.3390\/bioengineering11111057","type":"journal-article","created":{"date-parts":[[2024,10,24]],"date-time":"2024-10-24T04:11:38Z","timestamp":1729743098000},"page":"1057","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Tetracalcium Phosphate\/Monetite\/Calcium Sulfate Hemihydrate Biocement for Alveolar Bone Augmentation After Tooth Extraction in Pig Mandible"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5727-7180","authenticated-orcid":false,"given":"Katar\u00edna","family":"Vdoviakov\u00e1","sequence":"first","affiliation":[{"name":"Department of Morphological Disciplines, University of Veterinary Medicine and Pharmacy in Ko\u0161ice, Komenskeho 73, 041 81 Ko\u0161ice, 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