{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T14:23:00Z","timestamp":1787926980020,"version":"build-2784847793"},"reference-count":45,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T00:00:00Z","timestamp":1754870400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"School and Hospital of Stomatology, Fujian University","award":["AP00837OFF"],"award-info":[{"award-number":["AP00837OFF"]}]},{"name":"Clinical Division of Prosthodontics, University Clinic of Dentistry, Medical University of Vienna, Austria","award":["AP00837OFF"],"award-info":[{"award-number":["AP00837OFF"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioengineering"],"abstract":"<jats:p>Temporomandibular joint disorders (TMDs), particularly disc displacement with reduction (DDwR), are prevalent musculoskeletal conditions characterized by symptoms such as joint clicking, pain, and sometimes limited jaw movements. Accurate diagnosis requires a multidisciplinary approach, including clinical examination, imaging (MRI), and functional analysis. Among conservative treatment modalities, anterior repositioning splints (ARSs) are widely used to recapture the displaced discs and reposition the mandibular condyles. Determining the optimal therapeutic position (Th.P) for anterior repositioning splint fabrication remains challenging due to individual anatomical variability and a lack of standardized guidelines. This study introduces the controlled mandibular repositioning (CMR) method, which integrates clinical examination, imaging (MRI), computerized cephalometry, computerized condylography, neuromuscular palpation, and the Condylar Position Variator (CPV) to define an individualized Th.P. After treatment with CMR stabilizers (splints), the control MRI confirmed that in 36 out of 37 joints, the discs were repositioned to their normal position. There was a reduction in pain, as shown by VAS scores at the 6-month follow-up. This study demonstrated the effectiveness of the CMR method to find a precise therapeutic position, resulting in a 97.3% joint luxation reduction in DDwR. This study underscores the importance of precise, individualized Th.P determination for effective anterior repositioning.<\/jats:p>","DOI":"10.3390\/bioengineering12080865","type":"journal-article","created":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T17:22:07Z","timestamp":1754932927000},"page":"865","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Controlled Mandibular Repositioning: A Novel Approach for Treatment of TMDs"],"prefix":"10.3390","volume":"12","author":[{"given":"Diwakar","family":"Singh","sequence":"first","affiliation":[{"name":"Center for Clinical Research, University Clinic of Dentistry, Medical University of Vienna, 1090 Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"Landry","sequence":"additional","affiliation":[{"name":"Department of Education in Occlusion Medicine, Vienna School of Interdisciplinary Dentistry (VieSID), Advanced Education, 3400 Klosterneuburg, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6433-1085","authenticated-orcid":false,"given":"Martina","family":"Schmid-Schwap","sequence":"additional","affiliation":[{"name":"Division of Prosthodontics, University Clinic of Dentistry, Medical University of Vienna, 1090 Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Piehslinger","sequence":"additional","affiliation":[{"name":"Division of Prosthodontics, University Clinic of Dentistry, Medical University of Vienna, 1090 Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9","family":"Gahleitner","sequence":"additional","affiliation":[{"name":"Division of Radiology, University Clinic of Dentistry, Medical University of Vienna, 1090 Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-6124-2287","authenticated-orcid":false,"given":"Thomas","family":"Holzinger","sequence":"additional","affiliation":[{"name":"Center for Clinical Research, University Clinic of Dentistry, Medical University of Vienna, 1090 Vienna, Austria"},{"name":"Competence Center Artificial Intelligence in Dentistry, University Clinic of Dentistry, Medical University of Vienna, 1090 Vienna, Austria"},{"name":"Comprehensive Center for Artificial Intelligence in Medicine, Medical University of Vienna, 1090 Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yilin","family":"Wang","sequence":"additional","affiliation":[{"name":"Center for Clinical Research, University Clinic of Dentistry, Medical University of Vienna, 1090 Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiang","family":"Chen","sequence":"additional","affiliation":[{"name":"School and Hospital of Stomatology, Fujian Medical University, Fuzhou 350005, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohui","family":"Rausch-Fan","sequence":"additional","affiliation":[{"name":"Center for Clinical Research, University Clinic of Dentistry, Medical University of Vienna, 1090 Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,8,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"6","DOI":"10.11607\/jop.1151","article-title":"Diagnostic Criteria for Temporomandibular Disorders (DC\/TMD) for Clinical and Research Applications: Recommendations of the International RDC\/TMD Consortium Network* and Orofacial Pain Special Interest Group","volume":"28","author":"Schiffman","year":"2014","journal-title":"J. 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