{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T05:10:18Z","timestamp":1758949818580,"version":"3.44.0"},"reference-count":31,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T00:00:00Z","timestamp":1758758400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"NSTC","award":["112-2221-E-A49-009-MY3","111-2327-B-A49-006","112-2327-B-A49-002"],"award-info":[{"award-number":["112-2221-E-A49-009-MY3","111-2327-B-A49-006","112-2327-B-A49-002"]}]}],"content-domain":{"domain":["www.mdpi.com"],"crossmark-restriction":true},"short-container-title":["Bioengineering"],"abstract":"<jats:p>Schatzker type V bicondylar tibial plateau fractures present a major challenge due to the difficulty of achieving stable fixation with minimally invasive strategies. This study introduces a dual-thread lag and locking plate (DLLP) design that integrates lag screw compression with unilateral locking plate fixation. A custom-built compression evaluation platform and standardized 3D-printed fracture models were employed to assess biomechanical performance. DLLP produced measurable interfragmentary compression during screw insertion, with a mean displacement of 1.22 \u00b1 0.11 mm compared with 0.02 \u00b1 0.04 mm for conventional single lateral locking plates (SLLPs) (p &lt; 0.05). In static testing, DLLP demonstrated a significantly greater maximum failure force (7801.51 \u00b1 358.95 N) than SLLP (6224.84 \u00b1 411.20 N, p &lt; 0.05) and improved resistance to lateral displacement at 2 mm (3394.85 \u00b1 392.81 N vs. 2766.36 \u00b1 64.51 N, p = 0.03). Under dynamic fatigue loading simulating one year of functional use, all DLLP constructs survived 1 million cycles with &lt;2 mm displacement, while all SLLP constructs failed prematurely (mean fatigue life: 408,679 \u00b1 128,286 cycles). These findings highlight the critical role of lag screw compression in maintaining fracture stability and demonstrate that DLLP provides superior biomechanical performance compared with SLLP, supporting its potential as a less invasive alternative to dual plating in the treatment of complex tibial plateau fractures.<\/jats:p>","DOI":"10.3390\/bioengineering12101023","type":"journal-article","created":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T06:02:52Z","timestamp":1758866572000},"page":"1023","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Dual-Thread Lag\u2013Locking Screw Enhances Single Lateral Plate Fixation in Bicondylar Tibial Plateau Fractures: A Biomechanical Study"],"prefix":"10.3390","volume":"12","author":[{"given":"Ya-Han","family":"Chan","sequence":"first","affiliation":[{"name":"Department of Biomedical Engineering, National Yang Ming Chaio Tung University, Hsinchu 112304, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hsuan-Wen","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, National Yang Ming Chaio Tung University, Hsinchu 112304, Taiwan"},{"name":"Medical Device Innovation & Translation Center, National Yang Ming Chiao Tung University, Hsinchu 112304, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei-Che","family":"Tsai","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, National Yang Ming Chaio Tung University, Hsinchu 112304, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5958-0949","authenticated-orcid":false,"given":"Chun-Li","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, National Yang Ming Chaio Tung University, Hsinchu 112304, Taiwan"},{"name":"Medical Device Innovation & Translation Center, National Yang Ming Chiao Tung University, Hsinchu 112304, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,9,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/j.injury.2018.01.025","article-title":"A systematic literature review of tibial plateau fractures: What classifications are used and how reliable and useful are they?","volume":"49","author":"Millar","year":"2018","journal-title":"Injury"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/s12306-017-0514-8","article-title":"A review of the management of tibial plateau fractures","volume":"102","author":"Mthethwa","year":"2018","journal-title":"Musculoskelet. 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