{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T09:48:17Z","timestamp":1777024097141,"version":"3.51.4"},"reference-count":42,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T00:00:00Z","timestamp":1776902400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioengineering"],"abstract":"<jats:p>Scoliosis is a three-dimensional spinal deformity that may affect musculoskeletal alignment, respiratory mechanics, and neuromotor control. Rigid thoraco-lumbo-sacral orthoses (TLSOs) remain the primary conservative treatment during skeletal growth. Most brace systems rely on three-point pressure mechanisms that primarily generate lateral compression forces, while the contribution of shear components to corrective biomechanics has been insufficiently quantified. This study presents the experimental and analytical validation of the Canali Front-Push Orthopedic Brace, a rigid orthotic system designed to generate controlled compressive and shear forces through a frontal thrust mechanism and anterior rib cage engagement. By applying anterior force, the device reduces the frontal-plane lever arm, thereby limiting the mechanical moment that contributes to transverse plane rotation. An instrumented four-segment torso model derived from the internal CAD geometry of the brace was developed to independently measure upper compression, lower compression, and intersegmental shear forces. Controlled misalignment conditions (0 mm, 2 mm, and 4 mm) were introduced to simulate asymmetric engagement of the orthosis. Three load cell configurations (200 N and 500 N capacity) were tested. Mechanical endurance of the rack\u2013latch fastening system was also evaluated. A predictive shear\u2013misalignment relationship was derived and experimentally validated. Peak compressive forces reached approximately 370 N, while shear forces increased from less than 40 N under symmetric alignment (D0) to approximately 170 N under maximal misalignment (D4). Shear activation demonstrated near-linear proportionality to imposed geometric asymmetry (R2 &gt; 0.94). Following cyclic loading, the fastening system stabilized mechanically around 300 N. Measurement repeatability showed a coefficient of variation below 5%. These findings demonstrate that the brace produces predictable and controllable shear activation while maintaining high mechanical repeatability. The results provide a quantitative biomechanical framework for understanding shear-induced corrective mechanics in scoliosis bracing and support future studies integrating computational modeling and clinical validation. The proposed mechanical framework may contribute to the development of next-generation orthotic strategies aimed at controlling spinal rotation through vector modulation rather than purely compressive correction.<\/jats:p>","DOI":"10.3390\/bioengineering13050491","type":"journal-article","created":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T08:08:02Z","timestamp":1777018082000},"page":"491","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Mechanical Modeling and Experimental Validation of a Front-Push Orthopedic Brace: Compressive\u2013Shear Force Characterization Under Controlled Misalignment"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-1139-2989","authenticated-orcid":false,"given":"Mirko","family":"Zisi","sequence":"first","affiliation":[{"name":"Habitus et Motus, Via Nazionale 144, 40046 Alto Reno Terme, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincenzo","family":"Ricci","sequence":"additional","affiliation":[{"name":"VR Compositi di Ricci Vincenzo, Via Casale 20, 43035 Felino, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Rocchi","sequence":"additional","affiliation":[{"name":"Postura e Sport Srl, Via Alberto Savinio 26F, 43123 Parma, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincenzo","family":"Canali","sequence":"additional","affiliation":[{"name":"Postura e Sport Srl, Via Alberto Savinio 26F, 43123 Parma, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,4,23]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1097\/MOP.0b013e32833419ac","article-title":"Adolescent idiopathic scoliosis and genetic testing","volume":"22","author":"Ogilvie","year":"2010","journal-title":"Curr. 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