{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T04:54:45Z","timestamp":1781672085827,"version":"3.54.5"},"reference-count":31,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T00:00:00Z","timestamp":1781222400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioengineering"],"abstract":"<jats:p>(1) Background: Dental implant stability is influenced by multiple biomechanical, implant-related, and systemic factors, including bone density, implant geometry, biomechanical loading, smoking, osteoporosis, and diabetes mellitus. Computational bioengineering approaches may facilitate theoretical assessment of implant stability and support future risk-evaluation strategies. The aim of this study was to develop a conceptual computational framework for assessing theoretical implant instability using clinically relevant biomechanical and systemic parameters. (2) Methods: A multivariable computational framework was developed by integrating bone density, implant dimensions, implant mobility indicators, biomechanical loading conditions, smoking status, osteoporosis, and diabetes mellitus into a conceptual Implant Stability Index (ISI). Computational simulations and theoretical risk stratification procedures were used to evaluate framework behavior under different simulated conditions. (3) Results: The framework demonstrated the theoretical ability to differentiate between favorable and unfavorable implant stability conditions. Reduced bone density, increased implant mobility indicators, excessive biomechanical loading, and adverse systemic factors resulted in lower calculated ISI values and a higher theoretical instability risk. The framework further enabled the classification of simulated conditions into high-, moderate-, and increased-instability-risk categories. (4) Conclusions: The proposed Implant Stability Index represents a conceptual computational framework for integrating biomechanical, implant-related, and systemic factors associated with implant stability. Although not clinically validated, the framework may provide a proof-of-concept foundation for future studies involving clinical datasets, biomechanical simulations, and advanced computational modeling approaches.<\/jats:p>","DOI":"10.3390\/bioengineering13060684","type":"journal-article","created":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T03:27:21Z","timestamp":1781666841000},"page":"684","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Development of a Conceptual Implant Stability Index Framework for Computational Risk Assessment in Implant Dentistry"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7701-2307","authenticated-orcid":false,"given":"Liliana","family":"Sachelarie","sequence":"first","affiliation":[{"name":"Department of Dental Medicine, Apollonia University, 700511 Iasi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corina Laura","family":"\u0218tef\u0103nescu","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry, Ovidius University, 900527 Constanta, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodica Maria","family":"Murineanu","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry, Ovidius University, 900527 Constanta, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0772-2842","authenticated-orcid":false,"given":"Mircea","family":"Grigorian","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry, Ovidius University, 900527 Constanta, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agripina","family":"Zaharia","sequence":"additional","affiliation":[{"name":"Private Dental Practice, 900162 Constanta, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3803-9405","authenticated-orcid":false,"given":"Loredana Liliana","family":"Hurjui","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy, University Street 16, 700115 Iasi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,6,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Matijevi\u0107, L., Ivani\u0161evi\u0107, Z., Tomas, M., and Matijevi\u0107, M. (2026). Assessment of Implant Stability Using ISQ, Periotest, and CBCT in a Split-Mouth Pilot Study. Appl. Sci., 16.","DOI":"10.3390\/app16052358"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1111\/j.1600-0501.2012.02546.x","article-title":"A systematic review of the survival and complication rates of implant-supported fixed dental prostheses after a mean observation period of at least 5 years","volume":"23","author":"Pjetursson","year":"2012","journal-title":"Clin. Oral Implant. 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